Factors Influencing Symptom Severity at Discharge after Lobectomy and Sublobar Resection Through Video-assisted Thoracoscopic Surgery.

Objectives: This study investigates factors affecting symptom severity at discharge in patients who have undergone lobectomy and sublobar resection via video-assisted thoracoscopic surgery for pulmonary nodules, including both benign and malignant cases.

Methods: This retrospective analysis utilized data from a patient cohort in a randomized controlled trial at Zhongshan City People's Hospital. Symptom severity was assessed using the validated Perioperative Symptom Assessment for Lung Surgery questionnaire at 4 time points.

Boron-containing electron transport materials based on naphthalene diimide for organic solar cells: a theoretical study.

Electron transport materials (ETMs) are crucial for extracting and transporting electrons from the active layer to the cathode in organic solar cells (OSCs). In this work, we designed a series of ETM candidates (E1-E6) based on the experimentally synthesized (,-dimethylamino)propyl naphthalene diimide (NDIN) molecule by changing the nitrogen (N) atoms with boron (B) atoms at different positions. The electronic properties, electron transfer mobility, and interfacial properties were investigated using density functional theory (DFT) and time-dependent DFT (TD-DFT).

A Neutral Single-Molecule Carrier for Delivery of Phosphonate Drugs.

Phosphate/phosphonate-based drugs (PDs), as multinegative, hydrophilic molecules, face the greatest difficulty in diffusion across biological membranes, leading to poor bioavailability. Conventional drug delivery strategies to overcome this issue, including utilizing small-molecule prodrugs or nanoparticle carriers, often suffer from case-specific modifications or uncertainties in drug loading. Inspired by the anion coordination chemistry of natural phosphate transporters and artificial anion receptors, here, we present the first use of a neutral anion receptor, i.

Dithienylethene-based supramolecular chiroptical switch in phosphate-coordination-driven 2 : 2 duplexes.

Chiral photoswitches based on dithienylethenes have attracted extensive attention due to their unique chirality and optical activities, endowing them with potential applications in a multitude of fields. Herein, we present a new dithienylethene-based supramolecular chiroptical switch system driven by phosphate coordination. In the open-ring form, a mesocate structure (circular dichroism (CD) silent) is observed.

Manipulating the Isomerization of a Tris-azobenzene Cage by Anion Binding.

Here, we report a -symmetric tris-azobenzene cage comprising azobenzene cores and bis(urea) units. This system demonstrates efficient reversible photoisomerization and unprecedented anion-mediated switching modes. Specifically, the phosphate anion induces a concerted → isomerization with prolonged thermal relaxation ( = 37.

[Effects of Organic Materials Applied to Saline Soil on Crop Growth and Soil Saline-alkali Index].

To provide a theoretical basis for the scientific application of organic materials in salinized soil and the improvement of soil quality and to explore the response phenotype of an organic material-salinized soil-plant system, the salinized soil in Xinjiang was considered as the research object, and cotton, rape, and oil sunflower were considered as the test crops. Six treatments, including the control group, microbial agent, humic acid, organic fertilizer, biochar, and straw, were set up for indoor culture experiments. The effects of different organic materials on the growth of cotton, oil sunflower, and rape crops and soil saline-alkali indexes under moderate salinization soil conditions were analyzed, and the combinations with certain improvement effects were screened out.

Synthesis and Reactivity of Stable Open-Shell Gallylene.

Treatment of an excess of gallium metal with iodine and 1,2-bis[(2,6-dibenzhydryl-4-methylphenyl)imino]acenaphthene (Ar-bian) in toluene at reflux affords the deep green radical [Ar-bianGaI] (). Product can also be synthesized by reacting Ar-bian with "GaI" in toluene. The chloride and bromide derivatives, [Ar-bianGaCl] () and [Ar-bianGaBr] (), were prepared by the reactions of corresponding gallium(III) halides with Ar-bian in the presence of an excess of gallium metal in toluene.

Association between lactate dehydrogenase levels and all-cause mortality in ICU patients with heart failure: a retrospective analysis of the MIMIC-IV database.

Background: Heart failure (HF) patients admitted to the intensive care unit (ICU) often face high short-term mortality rates. This study aims to investigate the relationship between lactate dehydrogenase (LDH) levels and all-cause mortality in critically ill patients with HF.

Methods: Data from the MIMIC-IV database were extracted for subjects eligible for HF diagnosis.

Activation of CO, CS, and COS by α-Diimine-Stabilized Gallylenes.

Several gallylenes [LGaM(THF)] stabilized by an α-diimine ligand (L=[(2,6-iPrCH)NC(Ph)] ; M=Li, n=3, 3-Li; M=Na, n=4, 3-Na; M=K, n=1, 3-K) were prepared, which display diverse reactivities toward carbon dioxide and its sulfurized analogues. The reaction of 3 with CO yielded a trimeric carbonate complex [{LGa(CO)}{μ-K(THF)}] (4) and a dinuclear oxo-carbonate complex [K(THF)][LGa(μ-CO)(μ-O)GaL] (5) in one pot through reductive disproportionation of CO. For CS, two ethenetetrathiolate gallium complexes, [M(Solv)][LGa(μ-CS)GaL] (M=Na, Solv=THF, 6; M=K, Solv=DME, 7), were obtained via reductive coupling of CS.

SPOP expression is associated with tumor-infiltrating lymphocytes in pancreatic cancer.

Background: Speckle Type POZ Protein (SPOP), despite its tumor type-dependent role in tumorigenesis, primarily as a tumor suppressor gene is associated with a variety of different cancers. However, its function in pancreatic cancer remains uncertain.

Methods: SPOP expression and the association between its expression and patient prognosis and immune function were evaluated using The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx), The Tumor Immune Estimation Resource 2.

Impact of exercise dosages based on American College of Sports Medicine recommendations on lipid metabolism in patients after PCI: a systematic review and meta-analysis of randomized controlled trials.

Background: The impact of exercise dosages based on American College of Sports Medicine(ACSM) recommendations on lipid metabolism in patients after PCI remains unclear. This study conducted a meta-analysis of reported exercise dosages from the literature to address this knowledge gap.

Methods: A comprehensive search of databases was conducted to identify eligible randomized controlled studies of exercise interventions in patients after PCI, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.

Reduction of Ketones and Coupling of Ketyls by a Zn-Zn-Bonded Compound.

The α-diimine-ligated Zn-Zn-bonded compound [K(THF)][LZn-ZnL] (, L = [(2,6-PrCH)NC(Me)]) displays diverse reactivities toward a variety of ketones. In the reaction of with benzophenone or 4,4'-di--butylbenzophenone, a multielectron transfer process was observed to give bimetallic (Zn/K) complexes with both ketyl radical fragments and C-C coupled pinacolate moieties (products and ). In contrast, treating with 9-fluorenone only afforded pinacolate complex .

Activation of cyclopentadiene derivatives by an α-diimine-ligated Mg-Mg-bonded compound.

Heteroleptic, bimetallic (Mg/K) cyclopentadienyl complexes (2-4) were synthesized by the reaction of the Mg-Mg-bonded compound [K(THF)][LMg-MgL] (1, L = [(2,6-iPrCH)NC(CH)]) with cyclopentadiene derivatives, 6,6-dimethylfulvene, 6-(dimethylamino)fulvene, or 1,2,3,4-tetramethyl-1,3-cyclopentadiene. The reactions proceed through diverse pathways, including hydrogen abstraction, C-C coupling, and dehydrogenation, depending on the property of the polyene substrate, thus providing an access to alkali/alkaline earth metal cyclopentadienyl complexes.

Biomimetic Charge-Neutral Anion Receptors for Reversible Binding and Release of Highly Hydrated Phosphate in Water.

Control of phosphate capture and release is vital in environmental, biological, and pharmaceutical contexts. However, the binding of trivalent phosphate (PO ) in water is exceptionally difficult due to its high hydration energy. Based on the anion coordination chemistry of phosphate, in this study, four charge-neutral tripodal hexaurea receptors (L-L), which were equipped with morpholine and polyethylene glycol terminal groups to enhance their solubility in water, were synthesized to enable the pH-triggered phosphate binding and release in aqueous solutions.

Construction of Magnesium Phosphate Chemical Conversion Coatings with Different Microstructures on Titanium to Enhance Osteogenesis and Angiogenesis.

Titanium (Ti) and its alloys are widely used as hard tissue substitutes in dentistry and orthopedics, but their low bioactivity leads to undesirable osseointegration defects in the early osteogenic phase. Surface modification is an important approach to overcome these problems. In the present study, novel magnesium phosphate (MgP) coatings with controllable structures were fabricated on the surface of Ti using the phosphate chemical conversion (PCC) method.

Triplane technique for breast reconstruction after breast cancer surgery: A case series report.

Rationale: Implant-based breast reconstruction is an important method for post-mastectomy breast reconstruction. Currently, the most commonly used technique is the biplane technique. However, the high rate of postoperative complications, the inability of pockets to accommodate larger implants, and the expensive costs of biological mesh make the development of new surgical methods urgent.

Incorporation of an Anion-Coordinated Triple Helicate into a Thin Film for Choline Recognition in an Aqueous System.

Functional thin films, being fabricated by incorporating discrete supramolecular architectures, have potential applications in research areas such as sensing, energy storage, catalysis, and optoelectronics. Here, we have determined that an anion-coordinated triple helicate can be solution-processed into a functional thin film by incorporation into a polymethyl methacrylate (PMMA) matrix. The thin films fabricated by the incorporation of the anion-coordinated triple helicate show multiple optical properties, such as fluorescence, CD, and CPL.

One-Electron (2c/1e) Tin···Tin Bond Stabilized by -Phenylenediamido Ligands.

Odd-electron bonds, i.e., the two-center, three-electron (2c/3e), or one-electron (2c/1e) bonds, have attracted tremendous interest owing to their novel bonding nature and radical properties.

In Situ Photoisomerization of an Azobenzene-Based Triple Helicate with a Prolonged Thermal Relaxation Time.

The phosphate-coordination triple helicates A L (A=anion) with azobenzene-spaced bis-bis(urea) ligands (L) have proven to undergo a rare in situ photoisomerization (without disassembly of the structure) rather than the typically known, stepwise "disassembly-isomerization-reassembly" process. This is enabled by the structural self-adaptability of the "aniono" assembly arising from multiple relatively weak and flexible hydrogen bonds between the phosphate anion and bis(urea) units. Notably, the Z→E thermal relaxation rate of the isomerized azobenzene unit is significantly decreased (up to 20-fold) for the triple helicates compared to the free ligands.

pH-Dependent phosphate separation using a tripodal hexaurea receptor.

We demonstrate that a tripodal hexaurea receptor can selectively bind PO anions 12 hydrogen bonds with up to 3.8 × 10 M binding affinity in DMSO, which is 38-fold stronger than SO. This receptor facilitates the extraction of PO from strongly basic aqueous solutions into chloroform using liquid-liquid extraction, followed by its release as the HPO anion into an acidic solution.

Diverse Reactions of α-Diimine-Ligated Mg -Mg -Bonded Compound with Carbodiimides.

The α-diimine-ligated dimagnesium(I) compound [K(thf) ] [LMg-MgL] (1, L=[(2,6-iPr C H )NC(Me)] ) displays diverse reactivities toward carbodiimides (RN=C=NR) with different R substituents. In the reaction of 1 with Me SiNCNSiMe , one of the easily leaving trimethylsilyl groups is lost to yield the Me SiNCN moiety that either bridges two Mg centers (2) or terminally coordinated (3). In contrast, with the similarly bulky tBuNCNtBu, the carbodiimide inserts into Mg-Mg bond with accompanying C-H activation of a ligand or solvent (products 4 and 5).