TGEV-M up-regulates ATP5D to promote mPTP opening via inhibiting BIRC6-236aa encoded by circBIRC6-2.

Transmissible gastroenteritis virus (TGEV) infection can down-regulate circBIRC6-2 expression and induce mitochondrial permeability transition pore (mPTP) opening abnormally. BIRC6-236aa, encoded by circBIRC6-2, can suppress mPTP opening by interacting with VDAC1. However, the molecular mechanism of circBIRC6-2 downregulation by TGEV infection is unsuspected, and it is unclear that whether BIRC6-236aa can inhibit mPTP opening by post translational modifications (PTM) and downstream regulatory proteins.

Dynamic Leadership Mechanism in Homing Pigeon Flocks.

In recent years, an increasing number of studies have focused on exploring the principles and mechanisms underlying the emergence of collective intelligence in biological populations, aiming to provide insights for human society and the engineering field. Pigeon flock behavior garners significant attention as a subject of study. Collective homing flight is a commonly observed behavioral pattern in pigeon flocks.

Starling-Behavior-Inspired Flocking Control of Fixed-Wing Unmanned Aerial Vehicle Swarm in Complex Environments with Dynamic Obstacles.

For the sake of accomplishing the rapidity, safety and consistency of obstacle avoidance for a large-scale unmanned aerial vehicle (UAV) swarm in a dynamic and unknown 3D environment, this paper proposes a flocking control algorithm that mimics the behavior of starlings. By analyzing the orderly and rapid obstacle avoidance behavior of a starling flock, a motion model inspired by a flock of starlings is built, which contains three kinds of motion patterns, including the collective pattern, evasion pattern and local-following pattern. Then, the behavior patterns of the flock of starlings are mapped on a fixed-wing UAV swarm to improve the ability of obstacle avoidance.

circEZH2 inhibits opening of mitochondrial permeability transition pore via interacting with PiC and up-regulating RSAD2.

Transmissible gastroenteritis virus (TGEV) infection can lead to mitochondrial damage in porcine intestinal epithelial cells-jejunum 2 (IPEC-J2) cell line. The abnormal opening of mitochondrial permeability transition pore (mPTP) is the most important factor for mitochondrial damage. We previously demonstrated that circEZH2 could inhibit the abnormal opening of mPTP by binding miR-22.

A Dynamic TDMA Scheduling Strategy for MANETs Based on Service Priority.

Physical resource allocation strategy is a key factor affecting the performance of a mobile ad hoc network (MANET), which serves as a network model widely used in the sensor and detection field. For various perceived service information, it is significant for the allocation strategy to adapt to the dynamic service requirements and prioritize resource access for the service information with high priority to guarantee its real-time performance. In this paper, a novel dynamic time division multiple access (TDMA) scheduling strategy is proposed for MANETs.

Epigenetic Regulation of Key Enzymes CYP7a1 and HMGCR Affect Hepatic Cholesterol Metabolism in Different Breeds of Piglets.

Liver is the place where cholesterol is synthesized, transported, secreted, and transformed, thus liver takes an irreplaceable role in cholesterol homeostasis. Hepatic cholesterol metabolism differs between breeds, yet the molecular mechanism is unclear. In this study Large White (LW) and Erhualian (EHL) piglets (at birth and 25-day-old) were used, 6 each time point per breed.

Neural network adaptive sliding mode control for omnidirectional vehicle with uncertainties.

This paper presents a novel neural network adaptive sliding mode control (NNASMC) method to design the dynamic control system for an omnidirectional vehicle. The omnidirectional vehicle is equipped with four Mecanum wheels that are actuated by separate motors, and thus has the omnidirectional mobility and excellent athletic ability in a narrow space. Considering various uncertainties and unknown external disturbances, kinematic and dynamic models of the omnidirectional vehicle are established.

Phase transition of vortexlike self-propelled particles induced by a hostile particle.

When encountering a hostile particle, the avoidance behaviors of the vortex state of self-propelled particles exhibit phase transition phenomena such that the vortex state can change into a crystal state. Based on the self-propelled particle model and a molecular dynamics simulation, the dynamic response of the vortex swarm induced by a hostile particle (predator or obstacle) is studied. Three parameters are defined to characterize the collective escaping behaviors, including the order parameter, the flock size, and the roundness parameter.