Effects of various polishing processes on surface morphology, corrosion resistance, and RPD framework adaptation of SLM-printed dental Co-Cr alloys.

Purpose: This in vitro study aims to compare the effects of electrolytic polishing (EP), plasma electrolytic polishing (PP), dry electropolishing (DP), and their combination on the surface characteristics, corrosion resistance, and material reduction of selective laser melting (SLM) printed dental cobalt-chromium (Co-Cr) alloy.

Materials And Methods: Standard samples and removable partial denture (RPD) frameworks were SLM-printed and then polished using the following methods: mechanical polishing (MP), EP, PP, DP, PDP (PP + DP), DPP (DP + PP), and PDPP (PP + DP + PP). Surface characteristics were analyzed using optical profilometry, scanning electron microscopy (SEM), and x-ray photoelectron spectroscopy (XPS).

Multidimensional Toxicity of Organophosphate Pesticides and Mitigation Strategies for Agricultural Sustainability.

Organophosphate pesticides (OPs) remain essential yet controversial in global agriculture, demanding an urgent resolution of their efficacy-environmental protection paradox. This review provides an in-depth analysis of the toxicity mechanisms of OPs, primarily through oxidative stress induction, acetylcholinesterase (AChE) inhibition-mediated neurotoxicity, endocrine disruption, and multiorgan pathological effects. We highlight promising mitigation strategies, including natural antioxidants, advanced neuroprotective agents, neuroinflammatory inhibitors, nutraceutical interventions, and others, which synergistically alleviate the toxicity of OPs.

In vivo study of intraoral scanner trueness in partial edentulism.

The purpose of this study was to evaluate the trueness of complete-arch intraoral scanning of maxillary partially edentulous patients. Sixty-four patients with partially edentulous upper jaws were recruited. The intraoral digital impressions were obtained by Trios 3 scanner.

Circular transmission network and reverse contribution pattern of antibiotic resistance genes in the Qinghai-Tibet Plateau ecosystem.

The dissemination of antibiotic resistance genes (ARGs) poses a major global public health challenge, yet transmission mechanisms within extreme ecosystems are poorly understood. Using metagenomics and metagenome-assembled genome (MAG) analysis, we investigated ARG composition, risk, and pathways across a complete Qinghai-Tibet Plateau food chain (soil, earthworm, herbage, yak, pika, snowfinch, herdsman). Contrary to conventional theory, ARG assemblages correlated negatively with microbial diversity.

Effects of corn variety in whole-plant corn silage on dry matter intake, average daily gain and gastrointestinal tract bacteria and metabolites in Hu lambs.

Introduction: Whole-plant corn silage (WPCS) is an important roughage source in ruminant nutrition, and its nutritional value can vary significantly with corn variety. Understanding how different WPCS varieties influence gastrointestinal microbiota and metabolic profiles is essential for optimizing feed efficiency and animal health.

Methods: This study examined the effects of three corn varieties (2 introduced - Tunyu 168: TY; Yu silage 23: YQZ, and 1 local Longsheng 1: LS) in WPCS on gastrointestinal bacteria and metabolites in lambs.

Effects of substituting alfalfa silage with whole plant quinoa silage on rumen fermentation characteristics and rumen microbial community of sheep .

This study investigated the effect of different ratios of quinoa-to-alfalfa silage on the fermentation parameters, methane production, and rumen microbial community composition during fermentation trials. The objective was to evaluate the potential of quinoa as a viable silage material. Five treatment groups were set up with varying quinoa proportions of 0, 30, 50, 70, and 100%, and stored 60 days.

Enhancing antioxidant and barrier properties of collagen-based films via cellulose microfibrils modification with tannic acid-Fe complex.

Herein, we present a novel collagen-based packaging film that exhibits remarkable antioxidant activity, outstanding oxygen barrier properties, and exceptional mechanical strength. This film was developed by incorporating a combination of cellulose microfibrils (CMF) with modification of the metal-polyphenol network (MPN). The novelty lies in the application of CF with natural, layered, biodegradable, and renewable properties as a substrate and in situ loading of CMF-MPN complex to solve the problems of poor barrier and mechanical properties of CF, meeting the requirements of high antioxidant capacity, mechanical strength, and barrier properties in the food packaging field.

Clinical efficacy of maxillary digital removable partial dentures based on direct intraoral scanning and selective laser melting technology: a double-blind randomized controlled crossover clinical trial.

Objectives: A double-blind randomized controlled crossover clinical trial was conducted to comprehensively evaluate the treatment of maxillary removable partial dentures (RPDs) fabricated using a digital workflow.

Methods: A total of 58 patients were enrolled. The digital procedure involves direct intraoral scanning (IOS), digital design, selective laser melting (SLM) printing Cr-Co metal framework, and the usage of digitally printed resin cast.

Effects of Yeast Culture on Lamb Growth Performance, Rumen Microbiota, and Metabolites.

The effects of incorporating yeast culture (YC) into pelleted feeds on sheep production and the potential impact on rumen microbial populations, microbial metabolism, and fermentation have not been extensively studied. This study aimed to evaluate the effect of YC on growth performance, rumen tissue development, rumen fermentation, and rumen microflora in sheep and to explore the potential microbial mechanisms involved. Fifty healthy 3-month-old male lambs of small-tailed Han sheep, with an average weight of 28.

Shear bond strength of vat photopolymerization additive-manufactured zirconia to veneering ceramic.

Purpose: To evaluate the shear bond strength (SBS) of stereolithography (SLA), digital light processing (DLP) manufactured, and computer numerical control (CNC) milled zirconia to veneering ceramic.

Materials And Methods: Rectangular shaped zirconia substrates (10 × 5 × 5 mm) were manufactured through SLA, DLP, and CNC technology separately. Their surface roughness was measured and the surface topography was analyzed by atomic force microscope (AFM).

Adaptation of maxillary removable partial denture frameworks fabricated with a direct digital workflow: A randomized crossover clinical trial.

Objectives: To compare the adaptation of maxillary removable partial denture (RPD) frameworks fabricated through direct digital workflows with that of traditional cast frameworks and indirect digital frameworks.

Methods: The workflow for fabricating the digital cobalt-chromium framework encompassed intraoral scanning (IOS) using Trios 3, computer-aided survey and design, and subsequently either the lost-wax technique from a printed resin framework pattern (Framework B) or direct selective laser melting (SLM) (Framework C). The traditional cast framework (Framework A) was selected as a control.

The Impact of the Lactation Period Gut Microbiota of Two Different Beef Cattle Breeds on Spring-Born Calves.

To investigate the impact of maternal microbiota during lactation in different beef cattle breeds on their own immune levels, milk quality, and the growth and development of their offspring, this study measured the immune parameters, intestinal microbiota diversity, and milk quality of Pingliang red cattle and Simmental cattle, and performed a correlation analysis with the growth and development of their offspring. Our study showed that during lactation, Pingliang red cattle had significantly higher IL-6 levels than Simmental cattle, while the latter exhibited higher levels of immune factors such as IgG, IgA, IgM, IL-1β, and TNFα. The analysis of the intestinal microbiota of lactating cows found that Pingliang red cattle were rich in and , while Simmental cattle had a higher proportion of Actinobacteria.

Silencing PPAP2C inhibits lung adenocarcinoma migration and invasion via the ERK/JNK pathway.

Lung adenocarcinoma (LUAD) is a leading cause of cancer‑related death due to its aggressive nature and metastatic potential. The present study aimed to explore the expression of phospholipid phosphatase 2 (PPAP2C) in LUAD, and its effect on cell migration and invasion, with a particular focus on its association with the ERK/JNK signaling pathway and epithelial‑mesenchymal transition (EMT). The expression of PPAP2C in LUAD was analyzed using data from The Cancer Genome Atlas database.

Dietary resveratrol improves immunity and antioxidant defense in ewes by regulating the rumen microbiome and metabolome across different reproductive stages.

Introduction: Resveratrol (Res), a natural plant antitoxin polyphenol, is widely used in animal husbandry due to its antioxidant and anti-inflammatory properties, and current research has focused on humans, sows, and female mice. This study aimed to analyze the effects of dietary Res supplementation in ewes on antioxidant activity, immune responses, hormone levels, rumen microbiota and metabolites across various reproductive stages (estrus, pregnancy, and lactation).

Methods: Twenty-four healthy ewe lambs (Hu sheep, 2 months old) with a similar body weight (BW) (mean: 21.

Effects of yeast cultures on meat quality, flavor composition and rumen microbiota in lambs.

Since the banning of antibiotics, the use of feed additives to improve meat quality to satisfy people's pursuit of high quality has become a research hotspot. Yeast culture (YC) is rich in proteins, mannan oligosaccharides, peptides, and yeast cell metabolites, etc., and its use as a feed additive has a positive impact on improving meat quality.

Succession of rumen microbiota and metabolites across different reproductive periods in different sheep breeds and their impact on the growth and development of offspring lambs.

Background: The microbiota and metabolites in the gastrointestinal tracts of female animals at different reproductive periods are very important to the growth, development, and health of themselves and their offspring. However, the changes in the gastrointestinal microbiota and metabolites throughout reproductive period of different sheep breeds and their effects on the growth and development of offspring lambs are still unclear. Hence, this study presents an assessment of the reproductive hormone levels, immune levels, rumen microbiota, and metabolites in Hu sheep and Suffolk ewes at different reproductive periods and their effects on the growth and development of offspring lambs.

Zirconia specimens printed by vat photopolymerization: Mechanical properties, fatigue properties, and fractography analysis.

Purpose: The mechanical and fatigue properties of zirconia specimens printed by vat photopolymerization (VPP) were evaluated and compared with those of zirconia specimens milled by computer numerical control (CNC).

Materials And Methods: Bar-shaped specimens were printed by stereolithography (SL) and digital light processing (DLP). CNC-milled specimens were used as control samples.

Effects of Steviol Glycosides on Growth Performance, Ruminal Fermentation and Microbial Diversity of Hu Sheep.

The experiment was conducted to investigate the potential effects of steviol glycosides on growth performance, rumen fermentation processes, and microbial diversity in Hu sheep. A single-factor design was used for the trial. Twenty healthy weaned Hu lambs, possessing comparable body weights averaging 18.

3D Printed Porous Zirconia Biomaterials based on Triply Periodic Minimal Surfaces Promote Osseointegration In Vitro by Regulating Osteoimmunomodulation and Osteo/Angiogenesis.

The triply periodic minimal surface (TPMS) is a highly useful structure for bone tissue engineering owing to its nearly nonexistent average surface curvature, high surface area-to-volume ratio, and exceptional mechanical energy absorption properties. However, limited literature is available regarding bionic zirconia implants using the TPMS structure for bone regeneration. Herein, we employed the digital light processing (DLP) technology to fabricate four types of zirconia-based TPMS structures: P-cell, S14, IWP, and Gyroid.

Identification and validation of LINC01322 as a potential prognostic biomarker and oncogene promoting tumor progression in lung adenocarcinoma.

Our study identified a novel long noncoding RNA, LINC01322, that acts as an oncogene in lung adenocarcinoma progression. Cytoplasmic and nuclear RNA purification assays indicated that LINC01322 was localized in the cytoplasm and nucleus. Gene set enrichment analysis revealed the involvement of LINC01322 in the regulation of cell proliferation, migration, and the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway.

[Accuracy evaluation of recording maxillomandibular relation with the mandibular kinesiography].

Purpose: To evaluate the accuracy of recording maxillomandibular position relationship with the mandibular kinesiography by surface electromyography analysis of the masticatory muscles and MRI of temporomandibular joint (TMJ).

Methods: Eight edentulous patients were selected randomly, and the maxillomandibular position relationship was determined by mandibular kinesiography and traditional method respectively. Then the corresponding bite plates were made to wear.