Biofluorescence imaging as a valid alternative for dental calculus detection.

Background: Dental calculus is a major contributor to periodontal disease, and its effective removal depends on accurate detection. This study aimed to evaluate the detectability of dental calculus using quantitative biofluorescence imaging (BFI) and to assess its diagnostic accuracy compared to white-light imaging (WLI) and conventional visual-tactile (VT) examination.

Methods: Ten adults were enrolled, and 100 tooth surfaces from the buccal side of maxillary molars and the ligual side of mandibular anterior teeth were examined at three sites (mesial, central, distal), yielding 300 sites.

Predictive value of homologous recombination-related gene mutations in survival outcomes of first-line nivolumab plus chemotherapy for gastric cancer.

Background: Homologous recombination repair (HRR) gene mutations contribute to genomic instability. However, their clinical value in immune checkpoint inhibitor (ICI)-based treatments in gastric cancer remains unclear. Therefore, this study aims to investigate the efficacy of nivolumab plus chemotherapy according to the HRR mutation status in patients with advanced gastric cancer.

ED Visits Among Patients With Advanced Cancer Referred to Outpatient Palliative Care.

Importance: Emergency department (ED) visits among patients with cancer reflect unmet needs and may indicate poor care quality. Outpatient palliative care interventions may help minimize unnecessary ED visits and improve care alignment with patient preferences.

Objective: To explore characteristics of ED visits among patients referred to outpatient palliative care, evaluate the potential association of earlier referrals with reduced end-of-life ED visits, and examine when and where advance care planning was completed after outpatient palliative care referral.

Telemedicine Experiences of People Living with Amyotrophic Lateral Sclerosis at Home in South Korea.

Purpose: Telemedicine is advantageous in providing medical care to patients with mobility difficulties. This single-center study aimed to report on the provision of video televisits to people living with amyotrophic lateral sclerosis (pALS, ALS) who were registered with a home-based medical care (HBMC) team in a tertiary hospital in South Korea.

Materials And Methods: A retrospective cross-sectional study was conducted for pALS provided with video televisits by the HBMC team between July 2020 and February 2023.

Salt can antagonize the lethal effect of weak organic acids against Escherichia coli O157:H7 inoculated in laboratory culture media and acidic/acidified foods.

From the last several decades, previous studies have found that salt can increase the resistance of Gram-negative human-pathogenic bacteria to acidic environments in the presence of weak organic acids (OAAs), significantly increasing or extending the survival of Escherichia coli O157:H7, Salmonella enterica serovar Typhimurium, Shigella sp., and Cronobacter sp., particularly in acidified foods.

Gompertz-derived growth kinetics of serovar Bareilly inoculated in precooked ingredients for .

This study investigated the survival and growth parameters of serovar Bareilly inoculated in precooked ingredients (burdock, carrot, cheese, egg, ham, radish, and spinach) used in making at a given storage temperature of 25 °C, in order to predict the growth rate (GR) and lag time (LT) using the modified Gompertz equation. As a result, all ingredients gradually promoted the growth of sp., exceeding 10 to 10 CFU/g at 25 °C within 48 h.

Buffered by reflected glory? The effects of star connections on career outcomes.

Connections to exceptionally high-performing industry stars facilitate individuals' job attainment. But what are the career consequences for people who benefit initially from star connections? Using balance theory, we integrate social network and basking-in-reflected glory research to examine how high expectations resulting from the persistence of reflected glory affect the evaluation of star-connected employees' performance long after their work associations with stars have ceased. To preserve cognitive balance, evaluators may discount the poor performances of the star-connected.

A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells.

Injured liver cells undergoing chronic wound healing produce excessive amounts of extracellular matrix (ECM) components, such as collagen and fibronectin, leading to fibrosis. This process is largely mediated by transforming growth factor-β (TGFβ) signaling, which intersects with the tumor suppressor p53 pathway. However, the roles of specific p53 isoforms in this interaction remain unclear.

A Prospective Study on the Detection of Gastric Neoplasms Using Pepsinogen and Gastrin-17 Levels.

Background/aims: GastroPanel tests include gastrin-17 (G-17) levels in addition to pepsinogen (PG) and serology tests. The aim of this study was to identify significant test findings in patients with gastric neoplasms by comparing the findings of GastroPanel tests and conventional serum PG assays.

Methods: Consecutive individuals who underwent serological testing were included from May 2023 to August 2024.

Assessing statistical literacy in medical students and doctors: a single-centre, cross-sectional survey in South Korea.

Objective: Healthcare professionals must possess statistical literacy to provide evidence-based care and engage patients in decision-making. However, there have been concerns about healthcare professionals' inadequate understanding of health statistics. As an initial step in addressing the issue, we assessed the statistical literacy of medical students and doctors in South Korea by evaluating their comprehension of four statistical concepts: (a) single-event probability, (b) relative risk reduction, (c) positive predictive value and (d) 5-year survival rate.

Biofilm formation, slime production, and antibiotic susceptibility properties of the group isolated from fresh vegetables in the Republic of Korea.

This study aimed to characterize the ability of the group isolated from conventionally, organically or pesticide-freely grown vegetables to form biofilms with regard to cell surface hydrophobicity (CSH), slime production, and antibiotic susceptibility. Cellular properties (biofilm formation, CSH, and slime production) were measured using an in vitro microplate assay with crystal violet staining, adhesion to hydrocarbons assay, and Congo red broth method, respectively. Consequently, 16, 16, and 16 .

Out-of-hospital cardiac arrest event after cancer diagnosis: a korean metropolitan cohort study.

Background: The importance of assessing out-of-hospital cardiac arrest (OHCA) risk in cancer patients is increasing as cancer incidence rises in aging populations.

Objective: This study aimed to investigate the association between newly diagnosed cancer and OHCA risk using a metropolitan cohort from South Korea.

Methods: A population-based retrospective cohort study was conducted, linking the nationwide OHCA registry with the National Health Information Database.

The habituation to different concentrations of salt may variably influence the ability of Cronobacter sakazakii, Salmonella enterica serovar Enteritidis, Bacillus cereus, and Staphylococcus aureus to resist acid, bile salt, and heat stresses.

This study was to examine the relationship between preexposure to salt and stress-responsive resistance to acid, bile salt, and heat in Cronobacter sakazakii, Salmonella enterica serovar Enteritidis, Bacillus cereus, and Staphylococcus aureus. Stationary phase-grown cultures of C. sakazakii, S.

Epidemiologic trends and characteristics of cancer-related emergency department visits of older patients living with cancer in South Korea.

We aimed to investigate the demographic characteristics, common chief complaints, and diagnosis of geriatric cancer-related emergency department (ED) visits and trends of ED outcomes. This retrospective observational study included all ED visits in South Korea between 2016 and 2020. The study population was older people ≥ 65 years living with cancer who visited ED with cancer-related problems.

Neuroprotective Effect of Extract on Trimethyltin-Induced Memory Impairment in Rats.

Alzheimer's disease (AD) is a representative neurodegenerative disease characterized by the structural and functional degeneration of neurons. The present study investigated the neuroprotective effect of (ID) extract on trimethyltin (TMT)-induced memory deficit in the rat. Cognitive improving effect and neuronal activity of ID were assessed by using Morris water maze (MWM) test and choline acetyltransferase (ChAT), cAMP-response element-binding protein (CREB) immunohistochemistry.

An Eye on Extracellular Vesicles: Trends and Clinical Translations in Vision Research.

Purpose: To perform a review of research, funding, and clinical translation efforts for extracellular vesicles (EVs) within vision science.

Design: Retrospective analysis of publication, funding, and clinical trials data.

Methods: A pretrained large language model (Jina2) was used to create semantic embeddings for 41 282 abstracts from articles related to EVs archived on EMBASE and published between January 1966 and January 2024.

, an Non-TZF Gene, Enhances Salt Tolerance by Increasing the Expression of Both ABA-Dependent and -Independent Stress-Responsive Genes.

Salinity causes widespread crop loss and prompts plants to adapt through changes in gene expression. In this study, we aimed to investigate the function of the non-tandem CCCH zinc-finger (non-TZF) protein gene in response to salt stress in . , a gene from the non-TZF gene family known for its RNA-binding and RNase activities, was up-regulated under osmotic stress, such as high salt and drought.