Publications by authors named "Siyin Gong"
Protective Factors of Postendovascular Therapy Restenosis for Symptomatic Intracranial Arterial Stenosis: A Retrospective Analysis.
AJNR Am J Neuroradiol
August 2025
Background And Purpose: Symptomatic intracranial arterial stenosis (ICAS) markedly increases the risk of recurrent ischemic stroke, with high restenosis rates after endovascular therapy. This study aims to identify factors influencing restenosis within 1 year after endovascular therapy for ICAS, with the goal of reducing restenosis rates through interventions targeting protective and risk factors.
Materials And Methods: We conducted a retrospective analysis of symptomatic patients with ICAS who underwent endovascular therapy between January 2016 and June 2023 at our hospital.
Background: Pramipexole is thought to exert antidepressant effects in patients with Parkinson's disease (PD) and depression, but its efficacy compared with typical antidepressants is unclear. This meta-analysis aims to directly compare the safety and efficacy of pramipexole and antidepressants for depression in PD patients.
Methods: Twelve electronic databases including Cochrane, PubMed, Embase, Web of Science, CINAHL, PsycINFO, ProQuest, Open Grey, CBM, The CNKI, Wan Fang Data and VIP, and two clinical trial registry websites were systematically searched up to December 30, 2024.
Purpose: This study aimed to present clinical and immunological features in patients with neuroimmune complications of COVID-19 during Omicron wave in China.
Methods: Patients with neuroimmune complications associated with COVID-19 were retrospectively analyzed in Huashan Hospital from December 2022 to April 2023, during the widespread prevalence of Omicron variants in China. Demographic information, symptoms, electrophysiological findings, cerebrospinal fluid(CSF) test results and immunological markers, Magnetic Resonance Imaging(MRI) characteristics, treatment strategies and outcomes of these patients were reviewed and analyzed.
Rationale And Objectives: The correlation between collateral circulation and futile recanalization (FR) is still controversial, and few studies have explored the influence of comprehensive cerebral collateral circulation on FR after endovascular stroke treatment. Therefore, based on cerebral collateral recycle (CCR) status, we aimed to establish an effective scoring system to identify the probability of FR.
Methods: This was a multicenter retrospective cohort study.
Article Synopsis
- Elderly patients are significantly at risk for acute ischemic stroke caused by large vessel occlusion, which often leads to serious disabilities despite treatment. This study investigates the impact of cerebral collateral recycle (CCR) status on outcomes for these patients undergoing endovascular treatment (EVT).
- In a retrospective study involving 338 elderly patients, those with moderate to favorable CCR showed much higher rates of functional independence (63.3% and 31.1% respectively) compared to those with poor CCR (10.2%). The odds of achieving better outcomes were significantly higher for patients in the moderate and favorable CCR groups.
- The research concludes that the status of cerebral collaterals is a strong predictor of functional outcomes for elderly AIS
Article Synopsis
- Favorable venous outflow (VO) is identified as an important predictor for better clinical outcomes in patients with acute ischemic stroke from large vessel occlusion undergoing endovascular treatment.
- The study analyzed data from 515 patients and found that good VO significantly reduced the risk of intracranial hemorrhage and increased the chance of achieving functional independence after 90 days.
- The results suggest that favorable VO may improve outcomes partly by lowering the incidence of severe intracranial hemorrhage, highlighting its role in influencing clinical prognosis.
Validation of risk scoring models for predicting stroke-associated pneumonia in patients with ischaemic stroke.
Stroke Vasc Neurol
September 2016
Objective: Various risk scoring models have been developed to predict stroke-associated pneumonia (SAP). We aim to determine whether these risk models could effectively predict SAP in Chinese patients with ischaemic stroke (IS).
Methods: Consecutive patients with IS in West China hospital between January 2011 and September 2013 were included to assess the predictive performance of risk scoring models, including Chumbler's score, ADS and AISAPS.
Absence of NMDA receptor antibodies in patients with ovarian teratoma without encephalitis.
Neurol Neuroimmunol Neuroinflamm
May 2017
Vertebral artery hypoplasia and vertebral artery dissection: a hospital-based cohort study.
Neurology
February 2015
Objective: To test the hypotheses that vertebral artery hypoplasia (VAH) is associated with an increased risk of ipsilateral spontaneous vertebral artery dissection (sVAD) and that hypoplastic vertebral arteries (VAs) are more prone than dominant VAs to dissection.
Methods: In this case-control study, the population comprised 112 patients with sVAD and 224 age- and sex-matched controls treated at a high-volume center between 2005 and 2013. VAH and sVAD were diagnosed by digital subtraction angiography combined with noninvasive imaging findings.