Research progress on remote ischemic conditioning for improving prognosis of patients with acute ischemic stroke.

Acute ischemic stroke is a serious global health burden which has high disability and mortality rates. Remote ischemic conditioning, a non-intrusive treatment method, triggers a series of biochemical reactions and enhances the brain's resilience to ischemia-reperfusion injury by applying brief, reversible ischemic stimuli to the limbs. Remote ischemic conditioning offers neuroprotection by lowering oxidative stress, deterring neuronal apoptosis, inhibiting inflammation, protecting mitochondrial function, and preserving the blood-brain barrier.

Aging of textile-based microfibers in both air and water environments.

Textile-based microfibers (MFs) are a predominant source of global microplastics (MPs) pollution. Yet, less is known about the aging of textile-based MFs. This study explored the aging behavior of textile-based polyethylene terephthalate (PET) MFs with white (without pigment) and black (with carbon black as pigment) colors in both air and water environments.

Comorbidity of white matter lesions in parkinson's disease: a study on risk factors and phenotypic differences.

Background: Comorbidity of white matter lesions (WMLs) in idiopathic Parkinson's disease (PD) is becoming increasingly common.

Objective: To analyze the risk factors and phenotypic differences for the occurrence and severity of WMLs in patients with PD.

Methods: A total of 123 PD patients underwent clinical, laboratory, and magnetic resonance imaging (MRI) evaluations.

Edaravone dexborneol attenuates cognitive impairment in a rat model of vascular dementia by inhibiting hippocampal oxidative stress and inflammatory responses and modulating the NMDA receptor signaling pathway.

Exploring the intricate pathogenesis of Vascular Dementia (VD), there is a noted absence of potent treatments available in the current medical landscape. A new brain-protective medication developed in China, Edaravone dexboeol (EDB), has shown promise due to its antioxidant and anti-inflammatory properties, albeit with a need for additional research to elucidate its role and mechanisms in VD contexts. In a research setup, a VD model was established utilizing Sprague-Dawley (SD) rats, subjected to permanent bilateral typical carotid artery occlusion (2VO).

Coherent detection of the rotational Doppler effect measurement based on triple Fourier transform.

In recent years, the rotational Doppler effect (RDE) has been widely used in rotational motion measurement. However, the performance of existing detection systems based on the RDE are generally limited by the drastic reduction of signal-to-noise ratio (SNR) due to the influence of atmospheric turbulence, partial obscuration of the vortex beam (VB) during propagation, and misalignment between the optical axis of VB and the rotational axis of the object, which poses a challenge for practical applications. In this paper, we proposed a coherent detection method of the RDE measurement based on triple Fourier transform.

Retrospective Comparison of Outcomes Between Closed and Open Reduction for Developmental Dysplasia of the Hip in Children Aged 6-24 Months.

Purpose: We aimed to compare the outcomes between closed reduction (CR) and open reduction (OR) in children aged 6-24 months with developmental dysplasia of the hip (DDH) who could be reduced safely and stably by the closed reduction operation.

Methods: We retrospectively reviewed the medical records of 77 patients who underwent CR or OR for DDH. Fifty-one patients (56 hips) underwent CR, 26 (29 hips) underwent OR.

A non-randomized concurrent controlled trial of myofunctional treatment in the mixed dentition children with functional mouth breathing assessed by cephalometric radiographs and study models.

Objectives: This study aimed to examine the clinical effects of myofunctional treatment on children with functional mouth breathing by cephalometric radiographs and study models.

Methods: A total of 224 children (6-10 years old; 114 males and 110 females; SNA°: 82.24 ± 1.

Three-dimensional evaluation of pharyngeal airway and maxillary arch in mouth and nasal breathing children with skeletal Class I and II.

Objective: This study aimed to investigate whether the subjects with mouth breathing (MB) or nasal breathing (NB) with different sagittal skeletal patterns showed different maxillary arch and pharyngeal airway characteristics.

Methods: Cone-beam computed tomography scans from 70 children aged 10 to 12 years with sagittal skeletal Classes I and II were used to measure the pharyngeal airway, maxillary width, palatal area, and height. The independent t-test and the Mann-Whitney U test were used for the intragroup analysis of pharyngeal airway and maxillary arch parameters.

The Integrity of Cartilage Hinge in Song 2/3 Lateral Humeral Condylar Fractures in Children: A Retrospective Radiological Study in Two Centers.

Objective: For pediatric lateral condylar fractures (LCFs) of the humerus, it is often hard to determine the stability of the fracture based on the Song classification, especially for those categorized as Song stages 2 and 3. This study aims to define the characteristics of cartilage injury and assess the stability of LCFs classified as Song stages 2 and 3 on post-traumatic magnetic resonance imaging (MRI).

Methods: This was a retrospective study based on imaging data, conducted with a short follow-up period.

Metabolite Profiling and Transcriptome Analysis Revealed the Conserved Transcriptional Regulation Mechanism of Caffeine Biosynthesis in Tea and Coffee Plants.

Caffeine is a characteristic bioactive compound in tea and coffee plants, which is synthesized and accumulated extensively in leaves and seeds. However, little is known about the regulatory mechanism of caffeine synthesis in plants. This study compared the caffeine metabolite between tea and coffee plants.

An APSES Transcription Factor Xbp1 Is Required for Sclerotial Development, Appressoria Formation, and Pathogenicity in .

Sclerotinia diseases are important plant fungal diseases that, causes huge economic worldwide losses every year. is the main pathogen that results in mulberry sclerotia diseases. Sclerotia and appressoria play important roles in long-term pathogen survival and in host infection during life and disease cycles.

Role of integrin‑linked kinase in static compressive stress‑induced autophagy via phosphatidylinositol 3 kinase in human periodontal ligament cells.

Orthodontic tooth movement (OTM) is achieved by using mechanical stimuli, which lead to the remodeling of periodontal tissues. Previous findings have demonstrated that autophagy may be one of the cell responses to mechanical stress. As a key structure in the integrin pathway, integrin linked‑kinase (ILK) may play a role in the transmission of these mechanical signals.

A meta-analysis of transcriptomic profiles reveals molecular pathways response to cadmium stress of Gramineae.

As a non-essential heavy metal, cadmium (Cd) is toxic to plants. In the last 15 years, over 70 transcriptome studies have been published to decipher the molecular response mechanism against Cd stress in different plants. To extract generalization results from transcriptomic data across different plants and obtain some hub genes that respond to Cd stress, we carried out a meta-analysis of 32 published datasets.

Decreased saturated fatty acids, total cholesterol and LDL-C in sdd17 mice.

SDD17, a delta-15 desaturase from the fungus Saprolegnia can convert arachidonic acid to eicosapentanoic acid in yeast, plant embryos, and mammalian cells. Here, we generated transgenic mice that carried two copies of codon-optimized sdd17 cDNA within a non-coding domain of chromosome 6. RT-PCR analysis revealed that the foreign gene was expressed in the transgenic tissues.