Publications by authors named "Shuling Wan"

Aims: This study aimed to characterize the clinical features of headache in patients with non-thrombotic internal jugular vein stenosis (IJVS) and to identify associated risk factors.

Methods: This retrospective study consecutively enrolled patients with imaging-confirmed non-thrombotic IJVS from January 2021 through July 2024. Participants were divided into IJVS-headache and IJVS-without-headache groups based on clinical symptoms.

View Article and Find Full Text PDF

ObjectiveWe aimed to explore the development status, turning and key points, and emerging trends of the cerebral venous thrombosis (CVT).MethodsLiterature pertaining to CVT published from 2014 to 2023 in the Web of Science Core Collection database was searched. The 6.

View Article and Find Full Text PDF

Background And Objectives: Recent studies suggest a bidirectional relationship of dural arteriovenous fistula (DAVF) with cerebral venous thrombosis (CVT). We aimed to compare the characteristics of patients with DAVF with or without CVT and to analyze the risk factors for the coexistence of CVT in a DAVF population.

Methods: A total of 511 adult patients with DAVF were enrolled consecutively in our hospital from February 2019 through November 2022.

View Article and Find Full Text PDF

Introduction: Cerebral venous thrombosis (CVT) is a rare subtype of stroke. However, existing scales were insufficient to evaluate the overall severity of CVT. The aim of this study is to develop and validate a CVT severity scale.

View Article and Find Full Text PDF

Aims: To analyze intensive slow mannitol poststenting on attenuating stenting-related early adverse effects in cerebral venous sinus stenosis (CVSS).

Methods: This real-world study enrolled subacute or chronic CVSS patients from January 2017 through March 2022 and divided them into DSA only and stenting post-DSA groups. The later group was subdivided into control (without extra mannitol use) and intensive slow mannitol subgroup (immediate extra mannitol 250-500 mL, 2 mL/min infusion post-stenting) after signed informed consent.

View Article and Find Full Text PDF
Article Synopsis
  • Long-term remote ischemic conditioning (RIC) has benefits in various diseases, but the immediate effects of a single RIC session are not well understood, prompting this study to investigate these effects in healthy young men.
  • Participants underwent a RIC session involving cycles of restricted blood flow, with blood samples taken before, immediately after, and 2 hours post-intervention for proteomic analysis.
  • Results indicated significant changes in proteins linked to lipid metabolism, blood coagulation, and inflammation, suggesting that a single RIC could provide protective physiological responses beneficial in clinical emergencies.
View Article and Find Full Text PDF
Article Synopsis
  • Cerebral small vessel disease (CSVD) is a condition impacting small blood vessels in the brain, particularly common in older adults, and linked to various issues like strokes, cognitive decline, and gait problems.
  • Diagnosis relies on MRI scans, which reveal indicators such as small brain infarcts, white matter changes, and brain shrinkage.
  • The study aims to explore how inflammatory biomarkers in blood relate to MRI findings in CSVD, providing a foundation for future research in this area.
View Article and Find Full Text PDF
Article Synopsis
  • Remote ischemic conditioning (RIC) is a non-invasive method shown to have neuroprotective effects, and this study investigated its immediate impact on inflammation and coagulation in patients with chronic cerebral vascular stenosis.
  • The study involved 47 patients, comparing those with cerebral arteriostenosis and venostenosis, and found differences in inflammatory markers before and after a single RIC intervention.
  • Results indicated that RIC produced mixed effects, reducing fibrinogen levels but increasing interleukin-6 in arteriostenosis patients, while the potential benefits for venostenosis patients require further research.
View Article and Find Full Text PDF

It is well known that atherosclerotic vascular disease (ASVD) in the elderly is a global disease with high morbidity, mortality and disability, and plasma LDL-C correction is the most important strategy for ASVD control. However, a large proportion of patients failed to achieve their ideal LDL-C goals after statins use. Ezetimibe, a newly non-statin lipid-lowering agent, is an inhibitor of exogenous cholesterol absorption.

View Article and Find Full Text PDF

Cerebral cortical vein thrombosis (CCVT) is often misdiagnosed because of its non-specific diagnostic symptoms. Here, we analyzed a cohort of patients with CCVT in hopes of improving understandings and treatments of the disease. A total of 23 patients with CCVT (confirmed with high-resolution imaging), who had been diagnosed between 2017 and 2019, were enrolled in this cohort study.

View Article and Find Full Text PDF

Objectives: Previous studies have found that atropine can slow axial elongation and control the progression of myopia. Some ongoing trials have applied atropine combined with orthokeratology for myopia control, but few studies explored the effect of the strategy on axial elongation. This meta-analysis made a preliminary evaluation of the effect of atropine combined with orthokeratology on axial elongation to provide a reference for further researches.

View Article and Find Full Text PDF