Publications by authors named "Shuke Li"

Purpose: This study aims to develop and validate a computed tomography (CT)-based radiomics nomogram for predicting brain metastases in lung adenocarcinoma with anaplastic lymphoma kinase positive (ALK+).

Methods: Of 117 patients were retrospectively reviewed, among them, 34 patients from another hospital. Patients were randomly allocated into training (70%) and validation (30%) cohorts.

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Background: Thymic epithelial tumors (TETs), categorized predominantly as thymoma (T) or thymic carcinoma (TC), face a challenging prognosis and limited treatment options. Although chemotherapy remains the established treatment for advanced TETs, its responses tend to be short-lived. The emergence of immunotherapy, particularly programmed cell death-1 (PD-1) and programmed death ligand-1 inhibitors (PD-L1), is increasingly being regarded as a promising new treatment option for various malignancies.

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Background: High expression levels of programmed death receptor 1 (PD-1) and its ligand 1 (PD-L1) have been observed in thymic epithelial tumors (TET), suggesting their potential as prognostic indicators for disease progression and the effectiveness of immunotherapy in TET. The conventional method obtaining PD-L1 was challenging due to invasive sampling and tumor heterogeneity.

Methods: A total of 124 patients with pathologically confirmed TET (57 PD-L1 positive, 67 PD-L1 negative) were retrospectively enrolled and allocated into training and validation cohorts in a ratio of 7:3.

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Clean energy production and CO utilization have attracted increasing interest. Electrocatalysis represents an effective way to produce green hydrogen from water and reduce CO to valuable compounds. However, for either the hydrogen evolution reaction (HER) or the CO reduction reaction (CORR), the reaction efficiency is significantly limited by the slow kinetics of the oxygen evolution reaction (OER) at the anode, which consumes most of the input energy.

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Due to the large multi-elemental space desired for property screening and optimization, high-entropy alloys (HEAs) hold greater potential over conventional alloys for a range of applications, such as structural materials, energy conversion, and catalysis. However, the relationship between the HEA composition and its local structural/elemental configuration is not well understood, particularly in noble-metal-based HEA nanomaterials, hindering the design and development of nano-HEAs in energy conversion and catalysis applications. Herein, we determined precise atomic-level structural and elemental arrangements in model HEAs composed of RhPtPdFeCo and RuPtPdFeCo to unveil their local characteristics.

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Bamboo composite is an attractive candidate for structural materials in applications such as construction, the automotive industry, and logistics. However, its development has been hindered due to the use of harmful petroleum-derived synthetic adhesives or low-bonding biobased adhesives. Herein, we report a novel bioadhesion strategy based on lignin bonding that can process natural bamboo into a scalable and high-performance composite.

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Electrochemical reduction of nitrate to ammonia (NH) converts an environmental pollutant to a critical nutrient. However, current electrochemical nitrate reduction operations based on monometallic and bimetallic catalysts are limited in NH selectivity and catalyst stability, especially in acidic environments. Meanwhile, catalysts with dispersed active sites generally exhibit a higher atomic utilization and distinct activity.

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Depolymerization is a promising strategy for recycling waste plastic into constituent monomers for subsequent repolymerization. However, many commodity plastics cannot be selectively depolymerized using conventional thermochemical approaches, as it is difficult to control the reaction progress and pathway. Although catalysts can improve the selectivity, they are susceptible to performance degradation.

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Oxygen vacancies can regulate the coordination structure and electronic states of atoms, thus promoting the formation of surface-active sites and increasing the conductivity of the electrode material. This work presents a design for MXene@Ce-MOF composites with abundant oxygen vacancies. The hydroxyl groups on the surface of monolayer MXene attract cerium ions, which create surface defects in Ce-MOF and further promote the formation of oxygen vacancies.

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Multi-principal element alloys (MPEA) demonstrate superior synergetic properties compared to single-element predominated traditional alloys. However, the rapid melting and uniform mixing of multi-elements for the fabrication of MPEA structural materials by metallic 3D printing is challenging as it is difficult to achieve both a high temperature and uniform temperature distribution in a sufficient heating source simultaneously. Herein, we report an ultrahigh-temperature melt printing method that can achieve rapid multi-elemental melting and uniform mixing for MPEA fabrication.

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Reasonable regulating the electronic structure is one of the effective strategies for improving the conductivity of metal-organic frameworks (MOFs) based electrocatalysts. Herein, a series of Fe-MOF/Au composites grown in situ on Fe Foam (FF) were prepared through a hydrothermal and the controlled electrodeposition time strategy, in which the Fe Foam acts both as the conductive substrate and a self-sacrificing template. The electronic structure of the Fe-MOF/Au/FF composites can be finely adjusted by tailoring the electrodeposition time.

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The main challenge hindering the use of Pt nanoparticles (Pt NPs) for electrochemical applications is their high cost and agglomeration. Herein, a trifunctional electrode material based on a two-dimensional cerium-based metal organic framework (2D Ce-MOF) decorated with Pt NPs is constructed. The large specific surface area of the 2D Ce-MOF can effectively prevent the phenomenon of Pt NPs reaction.

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High-entropy nanoparticles have received notable attention due to their tunable properties and broad material space. However, these nanoparticles are not suitable for certain applications (e.g.

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Various alcoholic beverages containing different concentrations of ethanol are widely consumed, and excessive alcohol consumption may result in serious health problems. The consumption of alcoholic beverages is often accompanied by non-alcoholic beverages, such as herbal infusions, tea and carbonated beverages to relieve drunk symptoms. The aim of this study was to supply new information on the effects of these beverages on alcohol metabolism for nutritionists and the general public, in order to reduce problems associated with excessive alcohol consumption.

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