Effect of sensory art therapies on root canal treatment anxiety and high dental anxiety in adults: A systematic review with meta-analysis.

Objective: Root canal treatment is one of the most anxiety-provoking procedures in dental practice. Sensory art therapies can help control patient anxiety during the procedure. This systematic review aimed to synthesize the state of knowledge in this field and to examine whether sensory art therapies can reduce state anxiety during endodontics and in patients with high levels of dental anxiety.

Blocking the NR2B in the hippocampal dentate gyrus reduced the spatial memory deficits and apoptosis through the PERK-CHOP pathway in a rat model of sporadic Alzheimer's disease.

The hippocampal dentate gyrus (DG) integrates multiple sensory inputs and encodes spatial memory. DG-dependent spatial memory deficits have been observed in early Alzheimer's disease (AD). Our previous study demonstrated that glutamate (Glu)-mediated excitotoxicity contributes to spatial learning and memory impairment in AD.

Polarization-controlled metasurface for simultaneous holographic display and three-dimensional depth perception.

Simultaneous optical display and depth perception are crucial in many intelligent technologies but are usually realized by separate bulky systems unfriendly to integration. Metasurfaces, artificial two-dimensional optical surfaces with strong light-matter interaction capabilities at deep subwavelength scales, offer a promising approach for manufacturing highly integrated optical devices performing various complex functions. In this work, we report a polarization-multiplexed metasurface that can functionally switch between holographic display and Dammann gratings.

Searching to extrapolate embedding for out-of-graph node representation learning.

Out-of-graph node representation learning aims at learning about newly arrived nodes for a dynamic graph. It has wide applications ranging from community detection, recommendation system to malware detection. Although existing methods can be adapted for out-of-graph node representation learning, real-world challenges such as fixed in-graph node embedding and data diversity essentially limit the performance of these methods.

Honokiol ameliorates silica-induced lung fibrosis by inhibiting macrophage pyroptosis via modulating cGAS/STING signaling.

Silicosis is a life-threatening occupational disease because of inhaling silica dust, leading to chronic inflammation, pyroptosis, and fibrosis. Unfortunately, it is still lacking effective pharmacological intervention currently. Honokiol (HKL), a natural extract with biological activity from Magnolia bark, is known for its antioxidant and anti-inflammatory biological effects.

Case report: Successful PGT-M based on the identification of a spliceogenic variant in the gene through Minigene assay.

With the development of high-throughput sequencing, the genetic etiology of many diseases has been revealed. However, this has also led to the categorization of many variants as variants of uncertain significance (VUSs), presenting a major challenge in genetic counseling. A couple with a history of adverse pregnancies sought assisted reproductive technology.

A new genus and three newly recorded species of Encyrtidae (Hymenoptera, Chalcidoidea) from China.

A new genus and species of Encyrtidae (Hymenoptera: Chalcidoidea), Kang, Hu & Luo, (type species Kang, Hu & Luo, ), associated with insects inhabiting spp., and three newly recorded species for China, , and , are described from the Altun Mountain Nature Reserve, Xinjiang. Detailed illustrations of all species were included to support the identification and further study.

The Impact of the Soil Survival of the Pathogen of Wilt on Soil Nutrient Cycling Mediated by Microorganisms.

wilt of in the greenhouse is one of the most severe crop diseases in Shandong Province, P.R. China.

Hole-Free Nested Array with Three Sub-ULAs for Direction of Arrival Estimation.

Sparse arrays are of deep concern due to their ability to identify more sources than the number of sensors, among which the hole-free difference co-array (DCA) with large degrees of freedom (DOFs) is a topic worth discussing. In this paper, we propose a novel hole-free nested array with three sub-uniform line arrays (NA-TS). The one-dimensional (1D) and two-dimensional (2D) representations demonstrate the detailed configuration of NA-TS, which indicates that both nested array (NA) and improved nested array (INA) are special cases of NA-TS.

Research on Underdetermined DOA Estimation Method with Unknown Number of Sources Based on Improved CNN.

This paper proposes a joint estimation method for source number and DOA based on an improved convolutional neural network for unknown source number and undetermined DOA estimation. By analyzing the signal model, the paper designs a convolutional neural network model based on the existence of a mapping relationship between the covariance matrix and both the source number and DOA estimation. The model, which discards the pooling layer to avoid data loss and introduces the dropout method to improve generalization, takes the signal covariance matrix as input and the two branches of source number estimation and DOA estimation as outputs, and achieves the unfixed number of DOA estimation by filling in invalid values.

Effects of nitrogen input on soil bacterial community structure and soil nitrogen cycling in the rhizosphere soil of L.

L., goji berry, is a precious traditional Chinese medicine and it is homology of medicine and food. Its growth is heavily dependent on nitrogen.

Direction of Arrival Estimation of Generalized Nested Array via Difference-Sum Co-Array.

To address the weakness that the difference co-array (DCA) only enhances the degrees of freedom (DOFs) to a limited extent, a new configuration called the generalized nested array via difference-sum co-array (GNA-DSCA) is proposed for direction of arrival (DOA) estimation. We consider both the temporal and spatial information of the array output to construct the DSCA model, based on which the DCA and sum co-array (SCA) of the GNA are systematically analyzed. The closed-form expression of the DOFs for the GNA-DSCA is derived under the determined dilation factors.

Environmental Factors Drive Chalcid Body Size Increases with Altitudinal Gradients for Two Hyper-Diverse Taxa.

Body size is the most essential feature that significantly correlates with insects' longevity, fecundity, metabolic rate, and sex ratio. Numerous biogeographical rules have been proposed to illustrate the correlation between the body sizes of different taxa and corresponding geographical or environmental factors. Whether the minute and multifarious chalcids exhibit a similar geographical pattern is still little known.

Roles of the Notch Signaling Pathway in Ovarian Functioning.

The Notch signaling pathway regulates cell invasion, adhesion, proliferation, apoptosis, and differentiation via cell-to-cell interactions and plays important physiological roles in the ovary. This review summarizes current knowledge about the Notch signaling pathway in relation to ovarian functions and reveals the potential underlying mechanisms. We conducted an in-depth review of relevant literature to determine the current status of research into the Notch signaling pathway in relation to ovarian functioning and reveal potential underlying mechanisms.

CCL113, a novel sulfonamide, induces selective mitotic arrest and apoptosis in HeLa and HepG2 cells.

Targeting cell‑cycle regulation to hinder cancer cell proliferation is a promising anticancer strategy. The present study investigated the effects of a novel sulfonamide, CCL113, on cell cycle progression in cancer cell lines (HeLa and HepG2), a noncancerous cell line (Vero) and a normal human fibroblast cell line (TIG‑1‑20). The present results showed that treatment with CCL113 significantly decreased the viability of the cancer cells.

False Recognition of Emotionally Categorized Pictures in Young and Older Adults.

Normal aging is associated with the shift in motivational priorities from knowledge acquisition to emotion regulation. Current evidence indicates an age-related increase in preferences for positive over negative stimuli in true memory. In the present study, using the categorized pictures paradigm, we investigated whether older adults would exhibit a greater increase in false memory for positive versus negative lures, compared with young adults.

Exploration of the establishment of manganese poisoning rat model and analysis of discriminant methods.

Objective: We explored methods to establish an animal model of manganese poisoning and evaluate the feasibility of the determination method.

Methods: Twenty-four specific pathogen-free male rats were randomly divided into four groups: control, low-dose (15.0 mg/kg), middle-dose (25.

Amyloid β-Derived Diffusible Ligands (ADDLs) Induce Abnormal Autophagy Associated with Aβ Aggregation Degree.

Autophagy is disturbed in Alzheimer's disease (AD) and maintaining normal autophagy homeostasis is a new therapeutic strategy for AD treatment. Amyloid β-derived diffusible ligands (ADDLs), the most toxic species of which are oligomeric forms of amyloid β peptide (Aβ) that originate from amyloid β precursor protein (APP) via autophagy; however, whether ADDLs are involved in autophagy-related AD pathogenesis remains unclear. In this study, we primarily defined the specific subsets of ADDLs, A-0, A-12, A-24, and A-48, which were generated from ADDL aggregation mixtures at different time courses of assembly.