Wearable Device-Based Respiratory Complexity Analysis for Detecting Pulmonary Congestion in Patients With Heart Failure: Observational Exploratory Study.

Background: Excessive pulmonary congestion (PC) is a major contributor to heart failure (HF) deterioration and often necessitates emergency hospitalization. Early detection of PC-related respiratory abnormalities via wearable devices could enable prompt intervention and reduce admissions. However, the feasibility of using wearables to detect specific respiratory biomarkers of PC remains unclear.

[Exploratory study on quantitative analysis of nocturnal breathing patterns in patients with acute heart failure based on wearable devices].

Patients with acute heart failure (AHF) often experience dyspnea, and monitoring and quantifying their breathing patterns can provide reference information for disease and prognosis assessment. In this study, 39 AHF patients and 24 healthy subjects were included. Nighttime chest-abdominal respiratory signals were collected using wearable devices, and the differences in nocturnal breathing patterns between the two groups were quantitatively analyzed.

A novel sensor system to detect cerebral hemorrhage in rabbits through MIPS.

Background: Magnetic-induction phase shift (MIPS) was rarely used in vivo and clinically because of low sensitivity and nonquantitative detection. The conventional single excitation coil and single detection coil (single coil-coil) generates divergent excitation magnetic field, resulting in different sensitivity of different object positions.

Purpose: To improve the sensitivity and linearity of MIPS and object volume to realize quantitative detection, a novel sensor system was proposed.

An amplitude-based characteristic parameter extraction algorithm for cerebral edema detection based on electromagnetic induction.

Background: Cerebral edema is a common condition secondary to any type of neurological injury. The early diagnosis and monitoring of cerebral edema is of great importance to improve the prognosis. In this article, a flexible conformal electromagnetic two-coil sensor was employed as the electromagnetic induction sensor, associated with a vector network analyzer (VNA) for signal generation and receiving.

Research on the measurement of intracranial hemorrhage in rabbits by a parallel-plate capacitor.

Intracranial hemorrhage (ICH) carrying extremely high morbidity and mortality can only be detected by CT, MRI and other large equipment, which do not meet the requirements for bedside continuous monitoring and pre-hospital first aid. Since the biological tissues have different dielectric properties except the pure resistances, and the permittivity of blood is far larger than that of other brain tissues, here a new method was used to detect events of change at the blood/tissue volume ratio by measuring of the head permittivity. In this paper, we use a self-made parallel plate capacitor to detect the intracranial hemorrhage in rabbits by contactless capacitance measurement.

Noninvasive real-time assessment of intracranial pressure after traumatic brain injury based on electromagnetic coupling phase sensing technology.

Background: To investigate the feasibility of intracranial pressure (ICP) monitoring after traumatic brain injury (TBI) by electromagnetic coupling phase sensing, we established a portable electromagnetic coupling phase shift (ECPS) test system and conducted a comparison with invasive ICP.

Methods: TBI rabbits' model were all synchronously monitored for 24 h by ECPS testing and invasive ICP. We investigated the abilities of the ECPS to detect targeted ICP by feature extraction and traditional classification decision algorithms.

Twenty-four-hour real-time continuous monitoring of acute focal cerebral ischemia in rabbits based on magnetic inductive phase shift.

Background: As a serious clinical disease, ischemic stroke is usually detected through magnetic resonance imaging and computed tomography. In this study, a noninvasive, non-contact, real-time continuous monitoring system was constructed on the basis of magnetic induction phase shift (MIPS) technology. The "thrombin induction method", which conformed to the clinical pathological development process of ischemic stroke, was used to construct an acute focal cerebral ischemia model of rabbits.

A noninvasive flexible conformal sensor for accurate real-time monitoring of local cerebral edema based on electromagnetic induction.

Cerebral edema (CE) is a non-specific pathological swelling of the brain secondary to any type of neurological injury. The real-time monitoring of focal CE mostly found in early stage is of great significance to reduce mortality and disability. Magnetic Induction Phase Shift (MIPS) is expected to achieve non-invasive continuous monitoring of CE.

Noninvasive real-time detection of cerebral blood perfusion in hemorrhagic shock rabbits based on whole-brain magnetic induction phase shift: an experimental study.

Objective: This study aimed to perform experiments to investigate the change trend in brain magnetic induction phase shift (MIPS) during hemorrhagic shock of different degrees of severity and to find the correlation between brain MIPS value and commonly used physiological indicators for detecting shock so as to explore a noninvasive method suitable for prehospital real-time detection of cerebral blood perfusion in hemorrhagic shock.

Approach: The self-developed MIPS detection system was used to monitor the brain MIPS value in the whole process of hemorrhagic shock models of rabbits with different degrees of severity (control, mild, moderate, and severe) of shock in real time. Meanwhile, common physiological parameters, including arterial blood lactate (ABL), mean arterial pressure (MAP), heart rate (HR),core body temperature (CBT), regional cerebral blood flow (rCBF), and electroencephalogram (EEG), were also evaluated.

Experimental study on healthy volunteers based on magnetic induction brain edema monitoring system.

Background: Cerebral edema is a common secondary disease after stroke. It is very important to realize real-time continuous monitoring of cerebral edema for stroke patients.

Objective: A non-contact magnetic induction phase shift (MIPS) detection system is used to monitor the change of global brain electrical conductivity during cerebral edema.