Evaluation of Biodegradable Temporizing Matrix for Functional and Aesthetic Outcomes in Hand Soft-tissue Defect: A 3-year Retrospective Study.

Background: Hand soft-tissue defects compromise both function and aesthetics, significantly impacting quality of life. Traditional reconstructive techniques frequently lead to complications, such as donor-site morbidity and suboptimal aesthetic outcomes. The NovoSorb biodegradable temporizing matrix (BTM) may address these challenges by promoting tissue ingrowth.

A Donor-Acceptor-Type Two-Dimensional Poly(Arylene Vinylene) for Efficient Electron Transport and Sensitive Chemiresistors.

Two-dimensional (2D) conjugated polymers and their layer-stacked 2D conjugated covalent organic frameworks, such as 2D poly(arylene vinylene)s (2D PAVs), are emerging as promising polymer semiconductors for electronics and photocatalysis. However, achieving narrow optical band gaps and efficient electron transport remains a significant challenge for this class of materials to enhance the device's performance. Here, we report a donor-acceptor-type 2D PAV (2DPAV-TBDT-IT, where TBDT = thienyl-benzodithiophene and IT = s-indacene-1,3,5,7(2H,6H)-tetraone) synthesized via an Aldol-type 2D polycondensation approach.

Synthesizing Conductive Metal-Organic Framework Nanosheets for High-Performing Chemiresistive Sensors.

Two-dimensional conjugated metal-organic frameworks (2D -MOFs) are emerging as unique electrode materials with great potential for electronic applications. However, traditional devices based on -MOFs often utilize them directly in the powder or nanoparticle form, leading to weak adhesion to the device substrate and resulting in low stability and high noise levels in the final device. In this study, we present a novel approach utilizing thin -MOFs synthesized via a general MOF nanosheet sacrifice approach, enhancing their aspect ratio and flexibility for high-performance electronic applications.

Deltoid tuberosity index for proximal humerus fracture: reliability and a predictor of systemic osteoporosis in an Asian population.

Hypothesis And Background: Fragility fracture of the proximal humerus is a common occurrence. Current literature suggests that poor local bone density is a significant predictor of surgical fixation failure. The deltoid tuberosity index (DTI) is a simple radiographic tool that strongly correlates with local humeral bone mineral density (BMD), aiding surgical planning to consider adjuncts or arthroplasty.

Multi-metallic MOF based composites for environmental applications: synergizing metal centers and interactions.

The escalating threat of environmental issues to both nature and humanity over the past two decades underscores the urgency of addressing environmental pollutants. Metal-organic frameworks (MOFs) have emerged as highly promising materials for tackling these challenges. Since their rise in popularity, extensive research has been conducted on MOFs, spanning from design and synthesis to a wide array of applications, such as environmental remediation, gas storage and separation, catalysis, sensors, biomedical and drug delivery systems, energy storage and conversion, and optoelectronic devices, MOFs possess a multitude of advantageous properties such as large specific surface area, tunable porosity, diverse pore structures, multi-channel design, and molecular sieve capabilities, , making them particularly attractive for environmental applications.

Effects of Supercritical CO Treatment on Color, Lipid Oxidation, Heme Iron, Non-Heme Iron and Metmyoglobin Contents in Ground Pork.

The color, lipid oxidation, heme iron (HI) and non-heme iron (NHI) contents, metmyoglobin content and Soret band of myoglobin of ground pork subjected to supercritical CO treatment under different conditions, or to heat treatment (40°C, 2 h) and subsequent storage at 4°C were evaluated during 9-day period. Supercritical CO treatment significantly increased CIE L* and CIE b* values of ground pork during subsequent storage, while the HI content was slightly affected. In general, CIE a* value and metmyoglobin content were decreased.

Toward Smart Sensing by MXene.

The Internet of Things era has promoted enormous research on sensors, communications, data fusion, and actuators. Among them, sensors are a prerequisite for acquiring the environmental information for delivering to an artificial data center to make decisions. The MXene-based sensors have aroused tremendous interest because of their extraordinary performances.

Trypsin may induce cytokine storm in M1 macrophages, resulting in critical coronavirus disease.

Trypsin is a protease-activated receptor-2 (PAR2) activator that upregulates the interleukin (IL)-17 receptor signal in the airway epithelial cells and amplifies the inflammatory response, but does not modify the growth kinetics of the metapneumovirus. How does the coronavirus spread from cell to cell is yet an enigma. The present study analyzed the possible role of trypsin in the activation of coronavirus in vitro and in vivo.

Isolation, Identification and Antibacterial Mechanism of the Main Antibacterial Component from Pickled and Dried Mustard ( Coss. var. Bailey).

Our previous study showed that the ethyl acetate fraction (EAF) from an ethanolic extract of pickled and dried mustard ( Coss. var. Bailey) had significant antibacterial activity.

Resveratrol ameliorates myocardial fibrosis by regulating Sirt1/Smad3 deacetylation pathway in rat model with dilated cardiomyopathy.

Background: The aim of this study was to investigate the effects of Resveratrol (RSV) in rats with dilated cardiomyopathy (DCM).

Methods: Porcine cardiac myosin was used to set up rat model with DCM. RSV (10 mg/kg in RSV-L group and 50 mg/kg in RSV-H group) or vehicle was administered to rats with DCM once daily from the 28th day till the 90th day after the first immunization.

High Level of Inflammatory Cytokines in the Tears: A Bridge of Patients with Concomitant Exotropia and Dry Eye.

Concomitant exotropia have obvious symptoms of eye discomfort in adults, and the presence of ocular surface inflammation in patients may be important mediators between concomitant exotropia and dry eye. Oculus Keratograph eye comprehensive analyzer was performed to detect noninvasive tear break time, noninvasive tear height, and eye red index, while the ocular surface disease index and schirmer I testing were made. The levels of IL-6, IL-10, IL-17A, IL-12P70, INF-, and TNF- were detected in tears in patients with concomitant exotropia and healthy controls matched by age and gender through the Simoa technology.

DNA Methylation Pattern of CALCA and CALCB in Extremely Premature Infants with Monochorionic Triplets after Single-Embryo Transfer.

Compared with full-term peers, premature infants are more likely to suffer from neonatal diseases and death. Variations in DNA methylation may affect these pathological processes. Calcitonin gene-related peptide (CGRP) plays a complex and diversified role in reproduction and chronic inflammation, and participates in the functional maintenance of vascular adaptation and trophoblast cells during pregnancy.

The effect of patient positioning on the accuracy and reliability of assessment of knee range of motion over a telemedicine platform.

Introduction: Diagnostic accuracy is one of the key considerations of telemedicine usage in orthopedic surgery. The aim of this study was to determine the optimal patient positioning to achieve accurate and reliable visual estimation of the knee joint range of motion over a digital platform for telemedicine.

Methods: A single volunteer was recruited to perform a total of 120 discrete and random knee range of motion angles in three patient positions: sitting, standing and supine.

Age and Gender: Affecting the Positive Rates of Serum PAB and ANCA in Patients with Inflammatory Bowel Disease.

Inflammatory bowel disease (IBD) is a group of immune-mediated conditions. Immune activity is varied by age and gender. The present study is aimed at investigating the effect of age and gender on the positive rates of anti-Saccharomyces cerevisiae antibodies (ASCA), anti-neutrophil cytoplasmic antibodies (ANCA), anti-intestinal goblet cell antibodies (GAB), and antibodies to exocrine pancreas (PAB) in IBD patients.

DDIT4 Novel Mutations in Pancreatic Cancer.

Pancreatic cancer is one of the most common malignancies worldwide. This study is aimed at searching the possible genetic mutations and the value of novel gene mutation in the DNA damage-inducible transcript 4 (DDIT4) and signaling pathway in pancreatic cancer. Polymerase chain reaction (PCR) was performed to amplify the DNA sequences of DDIT4 from patients with pancreatic ductal adenocarcinoma.

[Research on community promotion and application of single acupoint electroacupuncture therapy for lumbar intervertebral disc herniation].

Objective: To observe the clinical effect of single acupoint [Yaotu (extra)] electroacupuncture (EA) therapy on lumbar intervertebral disc herniation (LIDH) and its promotion and application in community medical institutions.

Methods: This research adopted a three-level promotion model, and used multi-center collaboration topics as a platform. A total of 240 patients with LIDH were divided into a group A (top three hospital, 80 cases, 3 cases dropped off), a group B (secondary hospital, 80 cases, 8 cases dropped off), and a group C (community health center, 80 cases, 7 cases dropped off).

Platelet Antibodies in Infertility Patients.

Background: Platelet antigens can stimulate the body to produce platelet alloimmune antibodies through blood transfusion, pregnancy, and autoimmunity. In the blood of pregnant women, anti-platelet antibodies can cause embryo implantation failure, abortion, etc. if they are present.

Fabrication of N-doped carbons from waste bamboo shoot shell with high removal efficiency of organic dyes from water.

N-doped carbons were obtained from bamboo shoot shell via hydrothermal pretreatment under salt assistance followed by carbonization, using melamine as nitrogen source. The carbons with tubular morphology and surface areas in 406-489 m/g range were used as adsorbents for the removal of methyl orange (MO) and rhodamine B (RhB). Adsorption isotherms and kinetic fitting showed much better accordance with Freundlich model and pseudo-second-order, showing balanced capacity (q) of 50 mg/g for MO and 42 mg/g for RhB on the pristine carbons (BHC-800) at 25 °C.

Analysis of the burden and trend of injury in Sichuan, China, from 2006 to 2015: results from the national injury surveillance system.

Objective: This study investigates the distribution, burden and trends of injuries in Sichuan, China.

Design: A surveillance study using injury data collected by the National Injury Surveillance System.

Setting And Participants: 312 511 injury cases reported in the National Injury Surveillance System in Sichuan, China, from 2006 to 2015.

Stabilization of aqueous graphene dispersions utilizing a biocompatible dispersant: a molecular dynamics study.

Flavin mononucleotide sodium (FMNS) was recently reported as a highly efficient dispersant for the exfoliation of defect-free, few-layer, stabilized aqueous graphene dispersions. Most importantly, FMNS is innocuous and eco-friendly and can facilitate biomedical applications of graphene. Complementing those experimental studies, the influence of FMNS molecules on the aggregation behavior of graphene flakes in solution is investigated via all-atom molecular dynamics simulations.

Tailoring the Thermal and Mechanical Properties of Graphene Film by Structural Engineering.

Due to substantial phonon scattering induced by various structural defects, the in-plane thermal conductivity (K) of graphene films (GFs) is still inferior to the commercial pyrolytic graphite sheet (PGS). Here, the problem is solved by engineering the structures of GFs in the aspects of grain size, film alignment, and thickness, and interlayer binding energy. The maximum K of GFs reaches to 3200 W m K and outperforms PGS by 60%.

Effect of combined treatment with supercritical CO and rosemary on microbiological and physicochemical properties of ground pork stored at 4°C.

The effect of combined treatment with supercritical CO (2000psi, 35°C for 2h) and rosemary powder (2.5% and 5.0% (w/w)) on microbiological and physicochemical properties of ground pork stored at 4°C was investigated.

[Study on the clinical value of cervical spondylosis with articulatio atlantoepistrophica sublaxation].

Objective: To explore the effect of articulatio atlantoepistrophica sublaxation on the pathogenesis of cervical spondylosis, and provide a thread for diagnosis and treatment of cervical spondylosis with manipulation.

Methods: There were two groups in the study, which were non cervical spondylosis group and cervical spondylosis group. There were 333 patients in cervical spondylosis group, included 119 males and 214 females with the mean age of(48.