Publications by authors named "Shi-Cheng Yu"

Colorectal cancer (CRC), a malignancy affecting the colon and rectum, ranks as the third most common cancer worldwide and the second leading cause of cancer-related deaths. Early detection of CRC is crucial for preventing metastasis, reducing mortality, improving prognosis, and enhancing patients' quality of life. Genetic factors play a significant role in CRC development, accounting for up to 35% of the disease risk.

View Article and Find Full Text PDF
Article Synopsis
  • Surface reconstruction is important in fields like reverse engineering and oil exploration, but issues with data accuracy create uncertainties in the reconstructed surfaces.
  • This paper introduces a method for characterizing uncertainty using twin support vector regression, which combines data and efficiently uses high-confidence samples to define uncertainty intervals.
  • The approach incorporates well-path points to refine predictions and optimizes computation by solving smaller quadratic programming problems, and results show that it effectively reduces reconstruction uncertainties when well data is available.
View Article and Find Full Text PDF

We present a novel approach for measuring the differential static scalar polarizability of a target ion utilizing a "polarizability scale" scheme with a reference ion co-trapped in a linear Paul trap. The differential static scalar polarizability of the target ion can be precisely extracted by measuring the ratio of the ac Stark shifts induced by an add-on infrared laser shed on both ions. This method circumvents the need for the calibration of the intensity of the add-on laser, which is usually the bottleneck for measurements of the polarizability of trapped ions.

View Article and Find Full Text PDF

Iron metabolism dysregulation is tightly associated with cancer development. But the underlying mechanisms remain poorly understood. Increasing evidence has shown that long noncoding RNAs (lncRNAs) participate in various metabolic processes via integrating signaling pathway.

View Article and Find Full Text PDF

Objective: To evaluate the trend of notified incidence of pulmonary tuberculosis (PTB) in China at different periods by population and region and to explore the effect of TB prevention and control in recent years.

Methods: Using pooled data on TB cases reported by the TB Information Management Reporting System (TBIMS) from 2005 to 2020, we calculated the annual percentage change (APC) using the Joinpoint regression model.

Results: From 2005 to 2020, a total of 16.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to evaluate how residents perceive their built environment in hygienic cities and how it relates to their self-rated health (SRH) status, aiming to improve health-supportive development.
  • - Conducted via an online survey with 1,357 participants in Beijing's Chaoyang District, the study used logistic regression analysis to link aspects of the built environment to SRH.
  • - Key findings revealed that factors like green spaces, cleanliness, and residents' confidence in food and water safety significantly impacted their health ratings, suggesting that urban planning should prioritize residents' perceptions for better health outcomes.
View Article and Find Full Text PDF

Background: Tuberculosis (TB) poses a severe public health challenge in China and worldwide. This study evaluated the effects of age, period, and birth cohort on reported incidence trends of TB based on population and refined the characteristics of high-risk groups.

Methods: Aggregate data that reported pulmonary tuberculosis (PTB) cases from China Tuberculosis Management Information System (TBIMS) from 2006 to 2020 were used to analyze effect coefficients through the age-period-cohort (APC) model based on intrinsic estimator (IE) method, and converted them into relative risk (RR) to estimate trends.

View Article and Find Full Text PDF

Background: Charcot neuroarthropathy (CN) is a systemic disease characterized by progressive bone loss and destruction, which is usually closely related to diabetes, HIV, However, CN caused by syringomyelia accounts for only 5% of CN cases; the shoulder and elbow are most often involved, and the hip joint is rarely affected. As a rare factor, cervical spondylotic myelopathy (CSM) can be associated with syringomyelia, which is scarcely reported in the literature. Here, we present the first case report to date of CN of the hip caused by syringomyelia secondary to CSM.

View Article and Find Full Text PDF

Objective: This study aims to investigate the association of metabolic phenotypes that are jointly determined by body mass index (BMI) or fat mass percentage and metabolic health status with the ten-year risk of cardiovascular disease (CVD) among Chinese adults.

Methods: Data were obtained from a cross-sectional study. BMI and body fat mass percentage (FMP) combined with the metabolic status were used to define metabolic phenotypes.

View Article and Find Full Text PDF

Objective: This study was aimed at examining the trends and correlates of physical activity (PA) and sedentary behaviors among Chinese children.

Methods: A total of 4,341 subjects (6,936 observations) aged 6-17 years who participated in the China Health and Nutrition Survey (2004-2015) were included. Of the subjects, 41% participated in the survey twice or more.

View Article and Find Full Text PDF

Long noncoding RNAs (lncRNAs) are emerging as a new class of important regulators of signal transduction in tissue homeostasis and cancer development. Liquid-liquid phase separation (LLPS) occurs in a wide range of biological processes, while its role in signal transduction remains largely undeciphered. In this study, we uncovered a lipid-associated lncRNA, small nucleolar RNA host gene 9 (SNHG9) as a tumor-promoting lncRNA driving liquid droplet formation of Large Tumor Suppressor Kinase 1 (LATS1) and inhibiting the Hippo pathway.

View Article and Find Full Text PDF
Article Synopsis
  • A new subjective evaluation scale was created to assess the built environments under China's Hygienic City Initiative, focusing on five key areas: urban lifestyle, governance, basic functions, environmental sanitation, and amenities.
  • The scale was developed through expert input and resident interviews, with an emphasis on various statistical methods to confirm its reliability and validity.
  • Results showed high reliability (Cronbach's coefficient of 0.876 and split-half reliability of 0.796), indicating the scale is robust, while further studies are suggested for practical application.
View Article and Find Full Text PDF
Article Synopsis
  • The study analyzes notifiable infectious diseases in foreign nationals in China from 2004 to 2017, using data from the National Notifiable Infectious Disease Reporting System.
  • A total of 67,939 cases across 33 diseases were reported, with HIV, hepatitis B, and hand, foot, and mouth disease showing the highest incidences, particularly in Yunnan province.
  • The findings aim to enhance public health policy and responses by providing key epidemiological insights for future research and health strategies in China.
View Article and Find Full Text PDF
Article Synopsis
  • * Researchers found significant variation in soil selenium concentrations across different districts, with certain low (Quartile 1) and high (Quartile 4) selenium groups showing increased diabetes risk compared to a mid-range group (Quartile 2).
  • * The results suggest that excessive selenium in soil may raise diabetes risk, highlighting the need to consider environmental factors in health assessments for Chinese adults.
View Article and Find Full Text PDF

Rationale: Migration of endoclips and stitches into the duodenum after laparoscopic hepatectomy is incredibly rare with a poorly understood mechanism.

Patient Concerns: A 56-year-old woman who underwent laparoscopic left hepatectomy and cholecystectomy in August 2016 was admitted to our hospital with nausea and vomiting in December 2017.

Diagnoses: Abdominal computed tomography (CT) scan showed high density shades in duodenal ampulla.

View Article and Find Full Text PDF

This paper introduces the development and experiments of a 100 kV-level pulse generator based on a metal-oxide varistor (MOV). MOV has a high energy handling capacity and nonlinear voltage-current (V-I) characteristics, which makes it useful for high voltage pulse shaping. Circuit simulations based on the measured voltage-current characteristics of MOV verified the shaping concept and showed that a circuit containing a two-section pulse forming network (PFN) will result in better defined square pulse than a simple L-C discharging circuit.

View Article and Find Full Text PDF
Article Synopsis
  • A study reviewed the safety and effectiveness of the high-pressure balloon dilation (HPBD) technique for treating anterior urethral strictures, comparing it to direct vision internal urethrotomy (DVIU) performed on 56 patients between 2009-2012.
  • *The HPBD technique had a significantly shorter operation time and fewer major postoperative complications like urethral bleeding and urinary tract infections than DVIU.
  • *While there was no major difference in the long-term stricture-free rates at 36 months, HPBD showed significantly better results at 12 months, suggesting it could delay stricture recurrence.
View Article and Find Full Text PDF

Aim: To explore the feasibility and safety of laparoscopic colonic anastomosis using a degradable stent in a porcine model.

Methods: Twenty Bama mini-pigs were randomly assigned to a stent group (n = 10) and control group (hand-sewn anastomosis, n = 10). The anastomotic completion and operation times were recorded, along with histological examination, postoperative general condition, complications, mortality, bursting pressure, and the average anastomotic circumference (AC).

View Article and Find Full Text PDF

Respiratory damage is a main manifestation of severe Enterovirus 71 (EV71) infection. Polymorphisms of -403G/A (rs2107538), -28C/G (rs2280788), and In1.1T/C (rs2280789) in chemotactic chemokine ligand 5 (CCL5) have linked with many respiratory diseases.

View Article and Find Full Text PDF

Liver cancer is a common and leading cause of cancer death in China. We used the cancer registry data collected from 2009 to 2011 to describe the spatial distribution of liver cancer incidence at village level in Shengqiu county, Henan province, China. Spatial autocorrelation analysis was employed to detect significant differences from a random spatial distribution of liver cancer incidence.

View Article and Find Full Text PDF
Article Synopsis
  • The first-line treatment for castration-resistant prostate cancer (CRPC) is a chemotherapy drug called docetaxel, but some patients may not respond to it.
  • New therapeutic agents have been developed to treat CRPC either approved by the FDA or currently in clinical trials, targeting different biological processes.
  • This article reviews these innovative treatment options that can be considered after docetaxel has failed to help manage CRPC.
View Article and Find Full Text PDF
Article Synopsis
  • Testicular nuclear receptor 4 (TR4), or NR2C2, is a transcription factor part of the nuclear receptor family, initially found in human and rat tissues like the hypothalamus and testes.
  • Despite detailed research on its genetic and chromosomal aspects, understanding TR4's physiological roles has been challenging due to the absence of specific ligands.
  • Studies using TR4 gene knockout mice revealed significant health issues, including spinal curvature, subfertility, and prostate problems, while new tissue-specific knockout models will facilitate future research on TR4's functions.
View Article and Find Full Text PDF