Silent smoke, silent stress: Mussels as sentinels of cigarette pollution in coastal waters.

Cigarette butts are a major source of marine litter, releasing contaminants such as nicotine and its metabolite cotinine into aquatic ecosystems. This study assessed sublethal biochemical responses of Mytilus galloprovincialis exposed for 28 days to environmentally relevant concentrations (0.5, 5.

Emergent pollutants, escalating pressures: GenX effects on mussels in a changing environment.

Per- and polyfluoroalkyl substances (PFAS) are persistent pollutants with rising concern due to their stability and toxicity. The production of novel PFAS with shorter carbon chains in the environment raises concerns related to their stability and their potential toxicity in organisms. This study examines the effects of hexafluoropropylene oxide dimer acid ammonium (HFPO-DA, or GenX) on the marine mussel Mytilus galloprovincialis under different salinity conditions.

What do emerging PFAS tell us that the classic ones did not? Insights from in vitro assays.

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals that are recognized for their environmental persistence and potential toxicity. As regulatory pressure increases on legacy PFAS, emerging alternatives are being increasingly used. However, their environmental toxicological profiles remain poorly understood.

Interactive effects of Titanium-based compounds with Gadolinium and Mercury in Mytilus galloprovincialis.

The combined toxicity of metals in aquatic environments is a critical concern due to the complex interactions between different metal contaminants, as well as their interactions with other environmental factors. These combined effects often result in synergistic, antagonistic, or additive toxic responses, leading to heightened risks for aquatic organisms and ecosystems. This study investigates the toxicity of titanium in its bulk form (Ti) and as nanoparticles (nTi) when combined with other elements like gadolinium (Gd) and mercury (Hg), focusing on their effects on the mussel Mytilus galloprovincialis.

Does time matter? Organ-specific stress responses to cobalt in Mytilus galloprovincialis across salinities.

Cobalt (Co) pollution in aquatic ecosystems is rising due to its increased use in battery production. This study examines organ-specific biochemical responses of the mussel Mytilus galloprovincialis to Co exposure under three different salinities (20, 30, and 40) over 14 and 28 days. Mussels were exposed to 100 μg/L Co, and biomarkers of metabolism, oxidative stress, detoxification, and neurotoxicity were analyzed in the digestive gland, gills, mantle, and muscle.

Hidden costs of beauty: An in vitro study on the ecotoxicological impacts of ultraviolet filters and parabens on the bioindicator species Mytilus galloprovincialis.

Skincare is an increasing concern, as ultraviolet (UV) radiation causes skin diseases and photoaging, increasing demand for photoprotective personal care products (PCPs). PCPs contain UV filters, namely ecamsule (ECA), 2-ethylhexyl 4-methoxycinnamate (EHMC) and octocrylene (OC), and parabens, such as propylparaben (PPb) and methylparaben (MPb). These enter the environment, posing toxicity risks to marine species.

Effects of water temperature increase on gene expression, biochemical, and histopathological responses of the bivalve species Mytilus galloprovincialis to the antineoplastic drug 5-fluorouracil.

The present study aimed to assess the potential ecotoxicological effects of 5-fluorouracil (5-FU), an antineoplastic already found in aquatic ecosystems, towards the bivalve Mytilus galloprovincialis, considering actual and warming temperature scenarios. To this end, organisms were exposed for 28 days to increasing 5-FU concentrations (10, 100, and 500 ng/L) at control (17 ± 1.0 °C) and warming (21 ± 1.

Breaking new ground: Gadolinium and Microplastics co-exposure and biochemical alterations in marine clam Donax trunculus.

Toxicity of single rare earth elements (REEs) or microplastics (MPs) on organisms has been reported widely, however, their combined toxicity on bivalves has limited investigation. In this study, the effects of gadolinium (Gd, 500 μg/L), microplastics (MPs, Ø ≤ 150 μm, with 0.1 μg/L and 100 μg/L) and their mixture (0.

Gadolinium: a review on concentrations and impacts in marine and coastal systems.

This review synthesizes current knowledge on gadolinium (Gd) contamination in marine and coastal environments from 209 scientific publications. Of these, 83 studies were selected for detailed analysis, focusing specifically on marine invertebrate taxa to ensure a targeted examination of Gd's effects on key sentinel species within this group, with 69 papers (83.1 %) focusing on Gd concentrations in marine and coastal ecosystems, reporting concentrations ranging from 0.

From High-Tech To High-Risk? Unveiling the Acute Ecotoxicological Effects of Rare Earth Elements on Daphnia magna.

Technological advancement has brought significant environmental challenges, as its associated waste is difficult to manage and its long-term effects on ecosystems and biota remains uncertain. This study aimed to evaluate the acute toxicity of rare earth elements (REEs): lanthanum, cerium, praseodymium, neodymium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, scandium, and yttrium on the standard aquatic species Daphnia magna through a toxicity screening approach. Based on EC values, the most toxic element was yttrium (EC = 7.

Impact of marine heatwaves on Carcinus maenas crabs: Physiological and biochemical mechanisms of thermal stress resilience.

Marine heatwaves (MHWs), characterized by prolonged periods of elevated sea temperatures, pose significant threats to marine ecosystems, particularly affecting the physiology and behavior of marine organisms, including crustaceans. This study investigates the physiological and biochemical responses of males and females of Carcinus maenas crabs, after an acute exposure to an MHW, focusing on energy metabolism, oxidative status, and potential neurotoxicity. Specimens were exposed to controlled laboratory conditions simulating a temperature increase from 17 °C to 23 °C, and responses were analyzed in gills and hepatopancreas.

Are environmental levels of gabapentin (GBP) a cause for concern? Chronic reproductive effects of GBP in zebrafish.

GBP, a widely used antiepileptic drug, is frequently detected in aquatic environments due to inefficient removal in wastewater treatment. This study investigates the chronic reproductive toxicity of GBP in zebrafish (Danio rerio), a model species for endocrine disruption. Exposure began at 20 days post-fertilization (dpf), coinciding with sex differentiation, and continued for 130 days at environmentally relevant concentrations (1, 10, and 100 μg/L).

Could Mussel Populations Be Differentially Threatened by the Presence of Microplastics and Related Chemicals?

Mussels serve as indicators of anthropogenic chemical pollution; however, the effects of microplastics and plastic-related chemicals on their health performance remain an emerging issue. In this study, mussels were exposed to a polyamide (PA; 5 μg/L) and tricresyl phosphate (TCP; 1 μg/L) for 28 days. The exposures to the two contaminants were performed independently or in combination and lasted 28 days.

Trends and variability of marine heatwaves in Portuguese coastal waters.

Marine heatwaves (MHWs) represent a significant threat to marine ecosystems, particularly in vital fisheries regions such as the Portuguese coast. Understanding MHW dynamics at a finer spatial scale is essential for comprehending their impacts on the ecosystems. This study addresses this gap by analyzing historical MHW events from 1982 to 2023 and projecting future scenarios based on different greenhouse gas emission pathways.

The ecotoxicological effects of diclofenac and gentamicin on Mytilus galloprovincialis: What does in vivo reveal that in vitro fails to show?

This study investigated the toxicological effects of diclofenac (DIC) and gentamicin (GEN) on the gills (G) and digestive gland (DG) of Mytilus galloprovincialis through in vitro and in vivo assays. Biochemical markers related to oxidative stress, metabolic capacity, and neurotoxicity were evaluated at the end of each assay. For both assays, principal coordinates analysis (PCO) highlighted distinct biochemical profiles between G and DG, mostly related to higher basal values for several biomarkers in DG.

Live births and deaths of neonates born to adolescent mothers: analysis of trends and associations from a population study in a region of a middle-income country.

Background: Adolescent pregnancy is associated with adverse outcomes, and although there has been a global decline in the incidence of teenage pregnancies and neonatal deaths, the absolute number remains significant. This study aimed to evaluate temporal trends in live births and neonatal deaths from adolescent mothers, as well as to identify the effect of adolescent pregnancy on neonatal death.

Methods: This is a population-based study of all live births from mothers residing in Sao Paulo state, Brazil, between 2004 and 2020.

Investigating the effects of anthropogenic yttrium contamination: Biochemical alterations in the gills and digestive gland of exposed mussels (Mytilus galloprovincialis).

The rapid growth of electronic waste, including fluorescent lamp waste (FLW), has led to an increase in elements like yttrium (Y) and other rare earth elements (REE) in aquatic environments due to improper waste management. However, there are no guidelines for permissible concentrations of these elements in the environment. This study examines the biochemical impacts of varying Y concentrations (50, 100, and 200 µg L), mimicking a FLW discharge, on the gills and digestive gland of Mytilus galloprovincialis exposed for 14 days.

Gabapentin impairs visual development in zebrafish via retinal apoptosis and thyroid disruption.

Gabapentin (GBP), a pharmaceutical widely used for seizures and neuropathic pain, has emerged as a contaminant in global aquatic environments, raising concerns about its ecological impact. This study investigated the effects of environmentally relevant concentrations of GBP (0, 1, 10, 1000 μg/L) on visual development in zebrafish (Danio rerio). Behavioral assays showed that GBP exposure enhanced light sensitivity, as indicated by a significant increase in total travel distance (TTD) in all exposure groups compared to controls.

Neonatal mortality of live births with congenital diaphragmatic hernia in São Paulo State, Brazil: Failure of care?

Objective: The aim of this study was to analyze if the healthcare organization of perinatal care and availability of referral neonatal intensive care units (NICU) impacted congenital diaphragmatic hernia (CDH) neonatal mortality in the period 2004-2020. This study analyzed the spatial distribution of neonatal deaths of live births with CDH in São Paulo State, Brazil, and its association with NICU beds' availability.

Methods: Population-based study of all live births in São Paulo State from mothers residing in the same State, from 2004 to 2020.

Effects of the Interaction of Salinity and Rare Earth Elements on the Health of : The Case of Praseodymium and Europium.

The growing use of products containing rare earth elements (REEs) may lead to higher environmental emissions of these elements, which can potentially enter aquatic systems. Praseodymium (Pr) and europium (Eu) are widely used REEs with various applications. However, their ecotoxicological impacts remain largely unexplored, with poorly understood risks to wildlife.

Salinity modulation of neodymium and dysprosium toxicity in mussels: A comprehensive analysis of adult and sperm responses.

Neodymium (Nd) and dysprosium (Dy) are among the most commonly used rare earth elements (REEs) worldwide, leading to their increased concentrations in aquatic environments, with potential impacts on organisms. Additionally, organisms are also subjected to environmental stressors, such as salinity shifts, which can not only directly impact their health but also modulate the impacts of contaminants. Therefore, this study aimed to evaluate the effects of Nd and Dy on adult mussels and sperm of the species Mytilus galloprovincialis after 28 days and 30 min of exposure, respectively.

Revealing hidden risks: in vitro analysis of PFAS hazards in Mytilus galloprovincialis gills and digestive gland.

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals known for their persistence and bioaccumulation, leading to widespread environmental contamination. Despite their recognised environmental risks, particularly to aquatic wildlife, including marine invertebrates, detailed impact studies are limited. PFAS can be categorised according to the length of the compound chain, with short-chain PFAS announced as a safer alternative to the more commonly used long-chain PFAS.

Morphological . molecular identification of trematode species infecting the edible cockle across Europe.

Identifying marine trematode parasites in host tissue can be complicated when there is limited morphological differentiation between species infecting the same host species. This poses a challenge for regular surveys of the parasite communities in species of socio-economic and ecological importance. Our study focused on identifying digenean trematode species infecting the marine bivalve across Europe by comparing morphological and molecular species identification methods.

Short alkyl-chained Imidazolium-based Ionic Liquids: Promising green solution or potential environmental threat?

Ionic Liquids (ILs) are currently applied in a wide variety of fields, with promising outcomes in microalgae high value biocompounds extraction. The occurrence of these compounds in natural water systems, with their characteristic stability and low biodegradability, becomes a threat worthy of attention. In the present study, Dunaliella tertiolecta, Isochrysis galbana and Rhinomonas reticulata were exposed to 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([BMIM] TfN) for 72, 168 and 264 h, at 20 and 25 °C.

Space scan statistics to identify clusters of neonatal mortality associated with bacterial sepsis.

Our study aim was to identify high-risk areas of neonatal mortality associated with bacterial sepsis in the state of São Paulo, Southeast Brazil. We used a population-based study applying retrospective spatial scan statistics with data extracted from birth certificates linked to death certificates. All live births from mothers residing in São Paulo State from 2004 to 2020 were included.