Influence of lifestyles on physical, psychological, and cognitive co-morbidity among older adults with diabetes in rural area.

Background: The association between lifestyles and the co-occurrence of physical, psychological, and cognitive conditions in older adults living with diabetes, especially in rural settings, remains unclear. This study investigated the prevalence of co-morbidity and their association with lifestyle in a rural population of older adults with diabetes.

Methods: From 1st July to 31 August 2023, a cross-sectional study based on the whole cluster sampling method was conducted in Jia County, Henan Province, China.

Association between lifestyle behaviors and body mass index with blood pressure classifications among older adults with hypertension in China.

Objective: This study aimed to examine the association between lifestyle behaviors and body mass index (BMI) along with their potential interactions with the severity of blood pressure (BP) classifications among older adults with hypertension.

Methods: Among 17,441 participants, lifestyle behaviors were assessed, including smoking, drinking, dietary patterns, physical activity, and sleeping. Multinomial logistic regression was used to examine the association between lifestyle behaviors and BMI with BP classifications, and multiplicative interactions were included to estimate potential interactions.

Vacancy-Defect Single-Atom Catalysts for Tandem CO Electroreduction and Carbonylation Reactions from Flue Gas.

Tandem CO reduction with carbonylation reactions represents a promising approach to convert greenhouse gases into valuable chemicals. Herein, we propose a universal "N/O mixed pre-coordination pyrolysis" strategy to construct vacancy-defect single atom catalysts (Ni-, Mn-, Fe-, Co-, and Cu-NC) with M-N coordination microenvironment. This vacancy-defect endows Ni-NC with excellent performance for CO electroreduction, achieving a CO faradaic efficiency exceeding 90% across a wide range of current densities up to 300 mA cm.

Gram-Scale Green-Synthesis of High Purity Pinacols and Amides by Continuous Tandem Photocatalysis via a Negative Carbon Emission Process.

Solar-driven CO reduction for practical applications confronts significant challenges, including the waste of oxidation power and the difficulty in isolating reduction products. Herein, a pre-coordination restriction strategy is presented to hierarchically assemble CdS quantum dots (QDs), cobalt sites and Zr clusters in one metal-organic framework (MOF), resulting in the CdS@PCN-Co composite for simultaneous CO photoreduction and C-C coupling. Impressively, the yields of CO and pinacols with CdS@PCN-Co can reach 59.

The impact of personal health literacy and school health literacy environments on schoolteachers' health outcomes.

Background: The relationship between personal health literacy and health outcomes is clear, but the role of health literacy environments is often overlooked. This study examined associations between personal health literacy, school health literacy environments and health outcomes among schoolteachers.

Methods: A cross-sectional study was conducted among 7,364 schoolteachers in Zhengzhou, China.

Association between physical activity and sedentary behavior with cardiometabolic multimorbidity in the elderly hypertensive population: an observational and Mendelian randomization study.

Background: The causal relationships between physical activity (PA), sedentary behavior (SB), and the risk of cardiometabolic disease (CMD) in hypertensive populations remain unclear. We conducted a Mendelian randomization (MR) analysis to investigate these associations.

Methods: We conducted an observational analysis using a sample of 18,963 hypertensive population.

Comparison of Adrenal Vein Sampling Methods for Subtyping of Primary Aldosteronism: A Retrospective Observational Study.

Purpose: Although adrenal vein sampling (AVS) is the standard method for subtype diagnosis in patients with primary aldosteronism (PA), the methods used to sample the adrenal vein are not standardized. The aim of this study was to establish the optimal method for sampling the adrenal vein based on the pathological findings after surgery for PA.

Methods: We enrolled 168 consecutive patients who were diagnosed to have PA and underwent AVS at our institution between 2019 and 2023.

Spatial heterogeneity of blood pressure control and its influencing factors in elderly patients with essential hypertension: A small-scale spatial analysis.

Background: The blood pressure control status and its influencing factors in elderly patients with essential hypertension are complex. Existing studies often overlook spatial differences or utilize coarse spatial scales, which limits the understanding of the fine patterns of spatial heterogeneity and the design and implementation of further prevention and control policies.

Methods: In August 2023, A community-based survey was carried out in Jia County, China, involving a total of 19080 patients over 65 years old.

Evaluating the differences in healthy lifestyle behaviors between Chinese urban and rural residency after the termination of social distancing: analysis based on propensity score matching.

Background: During the COVID-19 pandemic, the social distancing has significantly affected the healthy lifestyle behaviors of residents. China ended social distancing on January 8, 2023, and the healthy lifestyle behaviors of residents after this time are unclear. The goal of this study was to evaluate the differences in healthy lifestyle behaviors between Chinese urban and rural residency after the termination of social distancing.

Confining Flat Ru Islands into TiO Lattice with the Coexisting Ru-O-Ti and Ru-Ti Bonds for Ultra-Stable Hydrogen Evolution at Amperometric Current Density and Hydrogen Oxidation at High Potential.

Effective hydrogen evolution reaction (HER) under high current density and enhanced hydrogen oxidation reaction (HOR) over a wide potential range remain challenges for Ru-based electrocatalysts because its strong affinity to the adsorbed hydroxyl (OH) inhibits the supply of the adsorbed hydrogen (H). Herein, the coexisting Ru─O─Ti and Ru─Ti bonds are constructed by taking TiO crystal confined flat-Ru clusters (F-Ru@TiO) to cope with above-mentioned obstacles. The different electronegativity (χ = 1.

CYP7B1 deficiency impairs myeloid cell activation in autoimmune disease of the central nervous system.

Dysregulation of cholesterol metabolism underlies neurodegenerative disease and is increasingly implicated in neuroinflammatory diseases, such as multiple sclerosis (MS). Cytochrome P450 family 7 subfamily B member 1 (CYP7B1) is a key enzyme in alternative cholesterol metabolism. A recessive mutation in the gene CYP7B1 is known to cause a neurodegenerative disease, hereditary spastic paraplegia type 5 and oxysterol accumulation.

Impacts of travel duration on urban-rural resident free vaccination behavior: Chinese COVID-19 vaccine booster dose evidence.

This study aimed to evaluate how the duration of travel affects the behavior of urban and rural residents regarding free COVID-19 vaccination, and provide scientific evidence for promoting free vaccination and building an immune barrier to cope with future epidemics. From August 3, 2022 to February,18,2023, A follow-up survey was conducted in urban and rural adults in four cities in China to collect information on socio-demographic factors, vaccination status and travel time for vaccination. Propensity score matching (PSM) analysis was deployed to measure the net difference of the enhanced vaccination rate between urban and rural residents in different traffic time distribution.

Assessing public health service capability of primary healthcare personnel: a large-scale survey in Henan Province, China.

Background: The public health service capability of primary healthcare personnel directly affects the utilization and delivery of health services, and is influenced by various factors. This study aimed to examine the status, factors, and urban-rural differences of public health service capability among primary healthcare personnel, and provided suggestions for improvement.

Methods: We used cluster sampling to survey 11,925 primary healthcare personnel in 18 regions of Henan Province from 20th to March 31, 2023.

Lifestyle behaviors and risk of cardiovascular disease and prognosis among individuals with cardiovascular disease: a systematic review and meta-analysis of 71 prospective cohort studies.

Background: Healthy lifestyle behaviors (LBs) have been widely recommended for the prevention and management of cardiovascular disease (CVD). Despite a large number of studies exploring the association between combined LBs and CVD, a notable gap exists in integration of relevant literatures. We conducted a systematic review and meta-analysis of prospective cohort studies to analyze the correlation between combined LBs and the occurrence of CVD, as well as to estimate the risk of various health complications in individuals already diagnosed with CVD.

Measuring General Health Literacy in Chinese adults: validation of the HLS-Q12 instrument.

Background: Health literacy measurement lays a solid foundation to identify associations with health outcomes and monitor population health literacy levels over time. In mainland China, most existing health literacy instruments are either knowledge-based or practice-based, making health literacy results incomparable between China and other countries. This study aimed to examine the reliability and validity of the 12-item Health Literacy Population Survey (HLS-Q12) in a general population of Chinese adults.

Quantifying the Adverse Effects of Long COVID on Individuals' Health After Infection: A Propensity Score Matching Design Study.

Objective: To evaluate the prevalence and influencing factors of long COVID, and measure the difference in health status between long COVID and non-long COVID cases.

Methods: A cross-sectional survey was conducted from February 1 to 8, 2023, using a stratified random sampling method in four regions (eastern [Changzhou], central [Zhengzhou], western [Xining] and northeastern [Mudanjiang]) of China. The survey collected COVID-19 patients' socio-demographic characteristics and lifestyles information.

Higher Circulating Lymphocytes and the Incidence of Pre-eclampsia and Eclampsia.

Excessive immune activation contributes to the onset of early dysfunction of the maternal-fetal interface, and it is closely linked to the development of pre-eclampsia. However, the effect of specific immune cells on the risk of pre-eclampsia and eclampsia remains controversial. We investigated the causal relationship between immune cells and pre-eclampsia and eclampsia.

Temporal changes in factors associated with COVID-19 vaccine hesitancy among Chinese adults: Repeated nationally representative survey.

Background: COVID-19 vaccine hesitancy has been cited as one of the main obstacles impacting vaccine coverage. However, factors that affect hesitancy may change over time. Understanding these evolving concerns and adapting strategies accordingly are crucial for effectively addressing vaccine hesitancy effectively and promoting public health.

How urban versus rural population relates to COVID-19 booster vaccine hesitancy: A propensity score matching design study.

During the COVID-19 pandemic, the vaccine hesitancy has significantly affected the vaccination. To evaluate the booster vaccine hesitancy and its influencing factors among urban and rural residents, as well as to estimate the net difference of booster vaccine hesitancy between urban and rural residents. We conducted a nationwide, cross-sectional Internet survey on 1-8 February 2023, and employed stratified random sampling technique to select participants (≥18 years old) from urban and rural areas.

Identification of Crucial Photosensitizing Factors to Promote CO -to-CO Conversion.

The sensitizing ability of a catalytic system is closely related to the visible-light absorption ability, excited-state lifetime, redox potential, and electron-transfer rate of photosensitizers (PSs), however it remains a great challenge to concurrently mediate these factors to boost CO photoreduction. Herein, a series of Ir(III)-based PSs (Ir-1-Ir-6) were prepared as molecular platforms to understand the interplay of these factors and identify the primary factors for efficient CO photoreduction. Among them, less efficient visible-light absorption capacity results in lower CO yields of Ir-1, Ir-2 or Ir-4.

Nonselective beta-adrenoceptor blocker use and risk of Parkinson's disease: from multiple real-world evidence.

Background: People with hypertension have a higher risk of developing Parkinson's disease (PD), epidemiological evidence suggests that multiple antihypertensives may affect the occurrence and development of PD with inconsistent results. With multisource data, we sought to determine whether specific antihypertensive classes elevated or reduced the risk for PD.

Methods: We used a mixed methods approach that combines 4 methodologies.

Association of joint exposure to various ambient air pollutants during adolescence with blood pressure in young adulthood.

The association of various air pollutants exposure during adolescence with blood pressure (BP) in young adulthood is uncertain. We intended to evaluate the long-term association of individual and joint air pollutants exposure during adolescence with BP in young adulthood. This cross-sectional study of incoming students was conducted in five geographically disperse universities in China during September and October 2018.

Transcriptome-wide association study reveals novel susceptibility genes for coronary atherosclerosis.

Background: Genetic risk factors substantially contributed to the development of coronary atherosclerosis. Genome-wide association study (GWAS) has identified many risk loci for coronary atherosclerosis, but the translation of these loci into therapeutic targets is limited for their location in non-coding regions. Here, we aimed to screen the potential coronary atherosclerosis pathogenic genes expressed though TWAS (transcriptome wide association study) and explore the underlying mechanism association.