Utilization of magnetic resonance imaging in the treatment of patients with acute myocardial infarction and intramyocardial hemorrhage.

Background: We assessed the diagnostic efficacy of magnetic resonance imaging (MRI) in patients with acute myocardial infarction (AMI).

Methods: In this study, 116 patients with acute myocardial infarction (AMI) underwent direct PCI intervention, admitted to our hospital between January 2018 and January 2021 were selected. Based on the presence of intramyocardial hemorrhage (IMH), they were divided into the IMH group and the non-IMH group.

P2X7-CaMKII drives 5-LOX nuclear translocation to impair microglial function after subarachnoid hemorrhage.

Background: Subarachnoid hemorrhage (SAH) is a common acute condition in neurosurgery, with microglial function playing a crucial role in determining patient outcomes. However, the involved mechanisms are complex and demand thorough investigation. In our study, we combined transcriptomic and metabolomic approaches to identify key regulators of microglial function, offering novel insights for potential therapeutic strategies in SAH treatment.

Robust dynamic event-triggered sliding mode control for lateral dynamics of intelligent electric vehicle.

This paper proposes a dynamic event triggering mechanism whose triggering characteristics can be designed for a robust sliding mode controller to solve the lateral motion control problem of intelligent electric vehicle in the presence of bounded matched disturbances. The motivation of current work mainly aims to alleviate unnecessary computing and communication of energy-constrained vehicle control systems by a large margin while ensuring its stability and robustness. The main contributions of the paper are summarized as follows.

The stress hyperglycemia ratio as a predictor of short- and long-term mortality in patients with acute brain injury: a retrospective cohort study.

Background: This study examines the Stress Hyperglycemia Ratio (SHR) as a predictor of mortality in acute brain injury (ABI) patients using the MIMIC-IV v3. 1 database.

Methods: In this retrospective cohort study of 2,423 ABI patients, SHR was calculated as SHR = [Admission blood glucose (mg/dL)] / [28.

Design of humidity sensor based on poly(sodium 4-styrenesulfonate) modified SnO for visual monitoring of plant growth environments.

Organic-inorganic hybrid materials hold great application prospects in electronic devices such as humidity sensors due to their unique interfacial effects and synergistic interactions. However, relatively few studies have been conducted on the sensitization mechanism of organic-inorganic hybrid materials. Herein, we report a high performance humidity sensor based on an organic-inorganic hybrid material of poly(sodium 4-styrenesulfonate)-modified amino-functionalized SnO (PSS-SnO).

Twist-Angle Controllable Transfer of 2D Materials via Water Vapor Intercalation.

Transfer technique has become an indispensable process in the development of two-dimensional materials (2DMs) and their heterostructures, as it determines the quality of the interface and the performance of the resulting devices. However, how to flexibly and conveniently fabricate two-dimensional (2D) twisted heterostructures with high-quality interfaces has always been a formidable challenge. Here, a quasi-dry transfer technique assisted by water vapor intercalation (WVI) is developed, which can be flexibly used to fabricate twisted heterostructures.

Predictors of poor functional outcome after endovascular treatment in patients with poor-grade aneurysmal subarachnoid hemorrhage.

Objective: Endovascular treatment (EVT) is considered an effective treatment for patients with poor-grade aneurysmal subarachnoid hemorrhage (aSAH). Although the prognosis of these patients seems to have improved in recent years, it is generally still considered poor. We analyzed our data to determine potential predictors of poor prognosis in these patients.

17.68% Efficiency Nonhalogenated Solvent-Processed Organic Solar Cell Modules Driven by Seed Crystal Strategy.

Organic solar cells now surpass 20% efficiency in small-area devices, but the use of chloroform as a solvent poses industrial scalability challenges because of its limited ability of uniform film formation and toxicity. High-boiling, non-halogenated solvents are being studied as alternatives, but their low solubility and slow evaporation complicate crystallization process. Here, the study introduces a seed crystal strategy by incorporating oligo (ethylene glycol)-modified small-molecule donors to optimize the nucleation and crystallization.

Silybin attenuates microglia-mediated neuroinflammation via inhibition of STING in experimental subarachnoid hemorrhage.

Background: The primary cause of subarachnoid hemorrhage (SAH) is the rupture of intracranial aneurysms. Over-activation of microglia following SAH is a primary driving force in early brain injury (EBI), which is a leading cause of poor outcomes. Silybin is a flavonoid compound extracted from Silybum marianum, a plant belonging to the Asteraceae family.

Analysis and prediction of subarachnoid hemorrhage burden in global, China, and Japan.

Background: Subarachnoid hemorrhage (SAH) remains a serious public health problem worldwide, especially in economically developed regions/countries. This study intends to thoroughly analyze the incidence, mortality, and disability-adjusted life years (DALYs) rate of SAH at the global, regional, and national levels. This study focused on the differences in SAH incidence between China and Japan from 1990 to 2019, and projected global, Chinese, and Japanese SAH incidence rates until 2030.

SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage.

Purpose: This study primarily elucidating the specific mechanism of SIRT2 on neuroinflammation and microglial pyroptosis in a mouse model of SAH.

Patients And Methods: CSF were collected from 57 SAH patients and 11 healthy individuals. C57BL/6 mouse SAH model was established using prechiasmatic cistern blood injection and the in vitro hemoglobin (Hb) stimulation microglia model.

Insulin Resistance Predicts Prognosis in Patients With Subarachnoid Hemorrhage.

Objective: The objective of this study was to determine whether insulin resistance (IR) could be used as a predictor of poor prognosis at 3 months after subarachnoid hemorrhage (SAH).

Methods: The study included patients aged 18 years or older with a confirmed diagnosis of SAH due to ruptured aneurysm from January 2021 to March 2024. Patients with confirmed diabetes mellitus and taking glucose-lowering drugs, or taking lipid-lowering drugs, or SAH not due to ruptured aneurysm, or comorbid systemic diseases were excluded.

Case report: Spindle cell sarcoma and pituitary adenoma in the sella region-a rare collision tumor.

Background: Collision tumors are defined as two or more distinctly bordered, mutually invasive tumors in the same anatomical region. Characterized by low incidence and lack of specificity, they often pose a significant challenge to disease diagnosis. Among these, collision tumors in the sella region are incredibly rare.

Manipulation of Moiré Superlattice in Twisted Monolayer-multilayer Graphene by Moving Nanobubbles.

In the heterostructure of two-dimensional (2D) materials, many novel physics phenomena are strongly dependent on the Moiré superlattice. How to achieve the continuous manipulation of the Moiré superlattice in the same sample is very important to study the evolution of various physical properties. Here, in minimally twisted monolayer-multilayer graphene, we found that bubble-induced strain has a huge impact on the Moiré superlattice.

Bisphosphonate-Anchored Self-Assembled Molecules with Larger Dipole Moments for Efficient Inverted Perovskite Solar Cells with Excellent Stability.

In the fabrication of inverted perovskite solar cells (PSCs), the wettability, adsorbability, and compactness of self-assembled monolayers (SAMs) on conductive substrates have critical impacts on the quality of the perovskite films and the defects at the buried perovskite-substrate interface, which control the efficiency and stability of the devices. Herein, three bisphosphonate-anchored indolocarbazole (IDCz)-derived SAMs, IDCz-1, IDCz-2, and IDCz-3, are designed and synthesized by modulating the position of the two nitrogen atoms of the IDCz unit to improve the molecular dipole moments and strengthen the π-π interactions. Regulating the work functions (WF) of FTO electrodes through molecular dipole moments and energy levels, the perovskite band bends upwards with a small offset for ITO/IDCz-3/perovskite, thereby promoting hole extraction and blocking electrons.

Self-Assembled Molecules with Asymmetric Backbone for Highly Stable Binary Organic Solar Cells with 19.7 % Efficiency.

The hole-transporting material (HTM), poly (3,4-ethylene dioxythiophene) poly(styrene sulfonate) (PEDOT : PSS), is the most widely used material in the realization of high-efficiency organic solar cells (OSCs). However, the stability of PEDOT : PSS-based OSCs is quite poor, arising from its strong acidity and hygroscopicity. In addition, PEDOT : PSS has an absorption in the infrared region and high highest occupied molecular orbital (HOMO) energy level, thus limiting the enhancement of short-circuit current density (J) and open-circuit voltage (V), respectively.

Stability of organic solar cells: toward commercial applications.

Organic solar cells (OSCs) have attracted a great deal of attention in the field of clean solar energy due to their advantages of transparency, flexibility, low cost and light weight. Introducing them to the market enables seamless integration into buildings and windows, while also supporting wearable, portable electronics and internet-of-things (IoT) devices. With the development of photovoltaic materials and the optimization of fabrication technology, the power conversion efficiencies (PCEs) of OSCs have rapidly improved and now exceed 20%.

Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.

Subarachnoid hemorrhage (SAH) is a type of stroke with a high disability and mortality rate. Apoptosis caused by massive damage to mitochondria in neuron cells and inflammatory responses caused by high extracellular ATP lead to poor outcomes. USP30 is a deubiquitinating enzyme that inhibits mitophagy, resulting in a failure to remove damaged mitochondria in a timely manner after SAH; nevertheless, the pathway through which USP30 inhibits mitophagy is unknown.

Menaquinone-4 attenuates ferroptosis by upregulating DHODH through activation of SIRT1 after subarachnoid hemorrhage.

Background: Menaquinone-4(MK-4), the isoform of vitamin K2 in the brain, exerts neuroprotective effects against a variety of central nervous system disorders. This study aimed to demonstrate the anti-ferroptosis effects of MK-4 in neurons after SAH.

Methods: A subarachnoid hemorrhage (SAH) model was prepared by endovascular perforation in mice.

Systemic Immune-Inflammation Index Predicts the Prognosis of Traumatic Brain Injury.

Objective: Systemic inflammation following traumatic brain injury (TBI) has been extensively studied over the past decades, as it contributes significantly to the pathophysiological injury mechanisms and subsequent poor outcomes. Systemic immune-inflammation (SII) index is a novel biomarker of systemic inflammatory response. However, its predictive value regarding TBI prognosis in clinical practice remains insufficiently investigated.