Pharmacological properties of Bergenia ciliata synthesized green zinc sulfide nanoparticles (ZnS-NPs) and zinc oxide nanoparticles (ZnO-NPs).

The conventional physical and chemical synthesis of nanomaterials is associated with multiple disadvantages, such as high energy consumption, high cost, time consumption, and the use of toxic chemicals that are not only hazardous in the manufacturing setup but are also harmful to the environment. To overcome such limitations, phytofabrication, i.e.

Scorpion (Hottentotta tamulus) venom pre-exposure delays functional recovery in mice following peripheral nerve injury.

Scorpion sting leads to profound challenges of central nervous system (CNS) impairments such as neuro-inflammation, unconsciousness, aberrant ion channels physiology, epilepsy and may become fatal due to heart failure. However persistence of Hottentotta tamulus venom in peripheral nerves and subsequent influence on regenerative process of injured peripheral nerve remains unknown. Current study reports the persistence of H.

A comprehensive laser-induced plasma diagnostics of hafnium using fundamental and second harmonics of pulsed Nd: YAG laser.

Despite the proven applications of laser induced breakdown spectroscopy (LIBS) in multielement analysis, its broad applications are often hindered by challenges related to signal stability, analytical reliability, higher standard deviation (RSD) and lower signal to noise ratio (SNR). Hafnium is an element of significant importance due to its critical role in nuclear reactors and high-temperature applications. In this study, the first comprehensive LIBS-based investigation of laser induced plasma diagnostics of hafnium is reported, to address both the knowledge gap and the existing limitations of the technique.

A High-Throughput Hydroponic Assay for Rapidly Screening Drought Tolerance in Potato.

Potato (Solanum tuberosum L.) yield is highly sensitive to drought stress, yet robust phenotyping methods for drought tolerance remain scarce. To address this challenge, we present a rapid, high-throughput hydroponic assay designed as an efficient pre-screening tool for evaluating potato cultivars and CRISPR-edited lines.

Frequency of Fast Track Extubation and Factors Affecting its Success in Adult Cardiac Surgery Patients: A Retrospective Analysis.

Objective: The primary objective is to identify how often do adult patients, who undergo elective open-heart surgeries are fast track extubated. Secondary objectives are to identify the causes of delayed extubation and to quantify the frequency of re-intubation and hospital stay in fast-track patients.

Study Design: Retrospective cross-sectional study.

Synthesis and optimization of silver-modified BiOCl/CuBiO heterostructure composite as an efficient visible light photocatalyst against reactive green 5 and turquoise blue dyes.

Reactive green 5 (RG 5) and turquoise blue (TB), widely used dyes, pose significant risks to water sources and human health, underscoring the need for effective removal techniques. A more environmentally sustainable approach is heterogeneous photocatalysis, which utilizes semiconductors. However, enhancing the efficacy of photocatalysts remains a challenge.

Turn-On-Fluorescence Sensor and Solid Sensory Chip for Cyanide Detection.

Herein, we report the synthesis of a triazole-ferric complex and evaluate its photophysical response at room temperature upon treatment with various anionic species, including SiO, ClO, ClO, CN, Cl, ClO, ClO, SO, NO, CHCOO, F, SCN, CO and CO. The probe molecule showed distinguishable absorption band pattern when subjected to KCN solution, showing selective behavior when compared with the other anionic species. Notably, non-emissive probe molecule, upon agitation with KCN solution, triggered a significant fluorescence with the emission signal intensity of 1207 a.

ELFN1 deficiency: The mechanistic basis and phenotypic spectrum of a neurodevelopmental disorder with epilepsy.

Purpose: Synaptic communication deficits are central to many neurodevelopmental disorders. However, for rare monogenic conditions, these disorders remain poorly defined, with limited understanding of their molecular etiology. A homozygous frameshift variant in the synaptic cell adhesion molecule ELFN1 was reported in a family with 3 affected siblings with epileptic encephalopathy, alongside a missense variant of uncertain significance in a cohort study involving a family with intellectual disability.

Back to bedside: Renal point-of-care ultrasonography (POCUS) by internal medicine resident physicians for identification of hydronephrosis in patients with acute kidney injury.

Background: Point-of-care ultrasonography (POCUS) has rapidly emerged as a valuable diagnostic tool in various medical conditions, including acute kidney injury (AKI) in the Western healthcare system. Its utility in the Middle East and Asian healthcare setups remains under-explored. This study aimed to assess the effectiveness of POCUS, performed by internal medicine residents (IMRs), in diagnosing hydronephrosis in AKI patients at a tertiary care training hospital in Qatar.

Trends of Sinusitis-Associated Orbital Cellulitis in Pediatric Patients: A Retrospective Cohort Review.

Background and objective Orbital cellulitis is mostly associated with sinusitis. The pediatric cases have a peculiar clinical presentation and variability with respect to different factors like season, type of sinus involved, and number of sinuses involved. In this study, we aimed to analyze the trends of sinusitis-associated orbital cellulitis in pediatric patients, which, we believe, would help physicians in managing these patients.

Molecular perspectives on Acacia Gum as a functional polysaccharide for biomedical and industrial applications: A review.

Acacia gum is a natural heteropolysaccharide derived from Acacia senegal and Acacia seyal. It has gained significant attention due to its unique macromolecular structure and functional biopolymer properties. This review critically evaluates its role in biomedical, pharmaceutical, and industrial applications, with emphasis on the molecular mechanisms that influence its interactions with biological and synthetic systems, especially the arabinogalactan polysaccharide complex of Acacia gum, which facilitates the electrostatic and hydrogen bonding interactions, influencing nanoparticle stability, drug delivery, and hydrogel formation.

BRSR-OpGAN: Blind radar signal restoration using operational generative adversarial network.

Many studies on radar signal restoration in the literature focus on isolated restoration problems, such as denoising over a certain type of noise, while ignoring other types of artifacts. Additionally, these approaches usually assume a noisy environment with a limited set of fixed signal-to-noise ratio (SNR) levels. However, real-world radar signals are often corrupted by a blend of artifacts, including but not limited to unwanted echo, sensor noise, intentional jamming, and interference, each of which can vary in type, severity, and duration.

Hepatic vena cava syndrome: a case report and literature review.

Background: Hepatic vena cava syndrome (HVCS) is an uncommon condition, with no prior reports from the Gulf area. In regions with limited resources, where this disease is found, there is a lack of data due to underdiagnosis. HVCS results from recurrent bacterial thrombophlebitis of the hepatic portion of the inferior vena cava (IVC), causing intimal thickening and obstruction, eventually leading to complications like liver cirrhosis and hepatocellular carcinoma.

Association of plasma levels of Sestrin2 with adiposity and metabolic function indices in healthy and diabetic subjects from Qatar Biobank.

Background: Despite the accumulating evidence from cellular and animal studies, the role of circulating Sestrin2, a stress-inducible antioxidant protein, in human cardiometabolic health remains largely unexplored. Hence, the current study aimed to investigate the association between circulating Sestrin2 and cardiometabolic risk factors in healthy and diabetic individuals.

Methods: This cross-sectional study leveraging data and plasma samples from the Qatar Biobank investigated the relationship between plasma Sestrin2 levels and various cardiometabolic indices in 326 healthy and 518 diabetic subjects.

Correction: Zahid et al. Fabrication and Characterization of Sulfonated Graphene Oxide-Doped Polymeric Membranes with Improved Anti-Biofouling Behavior. 2021, , 563.

In the original publication [...

Blood pressure variability and mortality in patients admitted with acute stroke in a tertiary care stroke centre (2016-2019): a retrospective cohort study.

Objectives: The influence of short-term variations in blood pressure (BP) in acute stroke on clinical outcomes remains uncertain. Our study explores the relationship between BP variability (BPV) from stroke admission up to 72 hours and in-hospital and 1-year mortality.

Design: Retrospective observational cohort study.

Dual-Interface Passivation of Wide-Bandgap Perovskite Films for Efficient Four-Terminal Perovskite-Organic Tandem Solar Cells.

Interface defects in perovskite solar cells (PSCs) can significantly impair device efficiency by promoting nonradiative recombination, hindering charge transport, and facilitating ion migration. In this work, we introduce a dual-interface passivation strategy utilizing 2-(-morpholino)ethanesulfonic acid potassium (MESK) and octylammonium iodide (OAI), targeting both the electron transport layer (ETL)/perovskite and perovskite/hole transport layer (HTL) interfaces to enhance the efficiency of wide-bandgap PSCs based on FACsPb(IBr) with a bandgap of 1.77 eV.

Influence of tulsi Ocimum sanctum extract on fish health: Growth, hematology, serum immune parameters, and antioxidant status in Common Carp.

Objective: In aquaculture, the trend is shifting towards using plant-derived alternatives that are abundant in phytochemicals as effective replacements for traditional antibiotics and synthetic feed additives. In the present study, the effects of tulsi Ocimum sanctum extract on growth performance, hemato-biochemical indices, serum immune parameters, and antioxidant parameters in Common Carp Cyprinus carpio were investigated.

Methods: Common Carp (mean body weight ± SD = 10.

Dietary Supplementation of as Probiotic Influenced the Growth Performance, Hematological Parameters, Immune Function, Antioxidant Status, and Digestive Enzyme Activity of Nile Tilapia Fingerlings ().

This study evaluated the impact of supplementation on growth, antioxidant status, digestive enzyme activities, hematological parameters, blood biochemistry, and immune responses in Nile tilapia () fingerlings. A total of 180 fingerlings (mean weight: 5 ± 0.5 g) were randomly assigned to four groups: a control group and three probiotic-supplemented groups with 10 (S-1), 10 (S-2), and 10 (S-3) CFU g of , following a completely randomized design.

The effects of ondansetron on diabetes and high-fat diet-induced liver disease: a critical role for protein tyrosine phosphatase 1B.

Introduction: The escalating prevalence of diabetes and non-alcoholic fatty liver disease (NAFLD) has intensified the search for effective therapeutic interventions. The current study investigates the potential of ondansetron, a Food and Drug Administration (FDA)-approved drug for conditions like nausea and vomiting, as a novel treatment option for these metabolic disorders.

Methods: A multifaceted approach, encompassing computational analyses, in vitro enzyme inhibition assays, and in vivo experiments in a high-fat diet (HFD)-induced disease model in rats were employed.

Aromatase deficiency due to novel mutation: a rare cause of maternal and fetal virilization.

Objectives: Aromatase deficiency is a rare autosomal recessive condition due to a mutation in the encoding aromatase enzyme. This enzyme protects the fetus and mother from excess androgens by converting them into estrogen. We are reporting a case of aromatase deficiency presented with atypical genitalia and maternal virilization due to a novel mutation in .

Root-applied brassinosteroid and salicylic acid enhance thermotolerance and fruit quality in heat-stressed 'Kyoho' grapevines.

Introduction: The increasingly severe global greenhouse effect has become an irreversible trend, significantly impacting viticulture regions through heat stress during various grape growth stages, especially under protected cultivation conditions where high temperatures frequently occur. Therefore, studying the impact of heat stress on grapevine growth and fruit quality across the entire growth and development period, along with effective mitigation measures, is crucial.

Methods: In this study, three-year-old 'Kyoho' grapevines were used as experimental materials, with four treatment groups: a control group, a hightemperature group (heat stress, HT), a high-temperature + brassinolide group (BR), and a high-temperature + salicylic acid group (SA).