Molecular perspectives on Acacia Gum as a functional polysaccharide for biomedical and industrial applications: A review.

Acacia gum is a natural heteropolysaccharide derived from Acacia senegal and Acacia seyal. It has gained significant attention due to its unique macromolecular structure and functional biopolymer properties. This review critically evaluates its role in biomedical, pharmaceutical, and industrial applications, with emphasis on the molecular mechanisms that influence its interactions with biological and synthetic systems, especially the arabinogalactan polysaccharide complex of Acacia gum, which facilitates the electrostatic and hydrogen bonding interactions, influencing nanoparticle stability, drug delivery, and hydrogel formation.