Efficacy and safety of chemoradiotherapy versus chemotherapy for resectable gastric cancer: a systematic review and meta-analysis.

Background: Gastric cancer is a leading cause of cancer-related deaths. Surgery combined with adjuvant treatments improves survival. This meta-analysis compares the efficacy of chemoradiotherapy (CRT) vs.

Adaptive deep brain stimulation targeting the subthalamic nucleus in a patient with Parkinson's disease: A CARE compliant case report.

Rationale: Adaptive deep brain stimulation (aDBS) represents a notable advancement in treating Parkinson's disease (PD), as it offers enhanced therapeutic outcomes and personalized management by adjusting stimulation parameters in real-time according to individual neural signals. This approach minimizes adverse effects commonly associated with standard continuous deep brain stimulation (cDBS). This case report describes the progress of a 62-year-old man with severe PD who demonstrated notable enhancement in motor symptoms and quality of life throughout a 3-month trial period using aDBS.

Importance of extracorporeal membrane oxygenation (ECMO) in congenital heart diseases: a systematic review.

Background: Congenital heart diseases (CHDs) represent a significant healthcare challenge with incidence rates of 17.9 per 1000 live births. Extracorporeal membrane oxygenation (ECMO) has become an invaluable therapeutic option providing essential aid to support both cardiac as well as pulmonary failure.

Comment on: Association Between Complex Indices of Blood Cell Types and Lipid Levels With All-Cause, Cardiovascular Mortality in Hemodialysis Patients: A Multicenter Retrospective Study.

We reviewed the study by Chen et al. on the association between blood cell indices, lipid levels, and mortality in hemodialysis patients. While the study provides valuable insights, several limitations affect its generalizability and validity.

Efficacy and safety of Nintedanib in idiopathic pulmonary fibrosis: A systematic review and meta-analysis.

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive, potentially fatal lung disorder characterized by scarring, leading to reduced lung function and respiratory failure. Nintedanib, a tyrosine kinase inhibitor, shows potential in slowing IPF progression, but uncertainties remain about its long-term efficacy and safety.

Objective: To evaluate the efficacy and safety of Nintedanib in idiopathic pulmonary fibrosis.

Is There Any Role of Zinc and Copper in Severity and Progression of Osteoarthritis? A Review.

Osteoarthritis (OA) is one of the most prevalent chronic diseases of the aging population, with an incidence of more than 250 million affected people and annual treatment costs exceeding $80 billion. Osteoarthritis involves pain, stiffness, reduced mobility, and swelling of the joints due to cartilage wear and tear and inflammation, which results in a broad system affecting the joints. This review focuses on the relationship between zinc and copper and the effects of these minerals on osteoarthritis.

Mortality trends of renal diseases due to hypertension in adults: an analysis of gender, race, place of death, and geographical disparities in the United States from 1999 to 2020.

Introduction: Hypertension-related renal diseases remain a significant healthcare concern, particularly in the United States, owing to the higher mortality rate across different demographic groups. This retrospective study aimed to analyze trends in mortality rates of hypertension-related kidney diseases stratified by age, race, gender, urbanization, state, and place of death.

Methods: Database of Center of Disease Control and Prevention (CDC) WONDER was used to extract death certificates among adults in US population from 1999 to 2020 using ICD codes.