J Trace Elem Med Biol
July 2025
Background: Heavy metal contamination in aquatic ecosystems poses significant ecological and human health risks, particularly through trophic transfer in food webs.
Objective: This study investigates the mean concentrations and trophic transfer of heavy metals (Cd, Cu, Cr, and Pb) across various environmental compartments (water, sediment, plankton) and trophic levels (three fish species: Catla. catla, Labeo rohita, and Cyprinus carpio) in an aquatic ecosystem.
Heavy metals (HMs) are one of the emerging micropollutants, which have been found a significant toxicant to the fish fauna; therefore, the current study aimed to examine HMs including Cd, Cr, Pb, and Cu concentrations in sludge and their accumulation in Oreochromis niloticus tissues along with growth and water quality in Biofloc Technology (BFT). Tilapia, initially weighing 0.40 ± 0.
View Article and Find Full Text PDFObjective: In aquaculture, the trend is shifting towards using plant-derived alternatives that are abundant in phytochemicals as effective replacements for traditional antibiotics and synthetic feed additives. In the present study, the effects of tulsi Ocimum sanctum extract on growth performance, hemato-biochemical indices, serum immune parameters, and antioxidant parameters in Common Carp Cyprinus carpio were investigated.
Methods: Common Carp (mean body weight ± SD = 10.
J Environ Sci Health A Tox Hazard Subst Environ Eng
April 2025
This study assessed the impact of silica exposure on 145 mine workers in Mianwali, Punjab, Pakistan, compared to 45 non-exposed individuals. Pulmonary function tests revealed significantly reduced lung function in exposed workers ( < 0.05), with declines in Forced Expiratory Volume in one second (FEV), Forced Vital Capacity (FVC), FEV/FVC ratio, Peak Expiratory Flow, and Forced Expiratory Flow at 25-75% of FVC (FEF25-75).
View Article and Find Full Text PDFComp Biochem Physiol Part D Genomics Proteomics
June 2025
Intracellular lipases can be broadly divided into two categories: neutral lipases and acid lipases. Adipose triglyceride lipase (ATGL), hormone-sensitive lipase (HSL), and monoacylglycerol lipase (MAGL) are three key neutral lipases responsible for the hydrolysis of triacylglycerol (TAG) in lipid droplets (LDs). Although these three TAG intracellular lipase genes have been identified and characterized in multiple model species, their evolutionary history remains largely unknown.
View Article and Find Full Text PDFBackground: Effective management strategies against tick infestations are necessary because tickborne diseases represent serious hazards to the health of humans and animals worldwide. The aim of this study was to examine the larvicidal and ovicidal properties of extract against a notorious tick species, Methodology: The maceration method was used to prepare the ethanolic extract of . The extract was then used in an adult immersion test (AIT) and larval packet test (LPT) to asses the plant's toxicity.
View Article and Find Full Text PDFThis paper investigates the characteristics of ternary-hybrid nanoliquid for time-dependent Darcy-Forchheimer flow. Formulation is based for mixture of water subject to ternary nanoparticles with different shapes like (platelet, spherical and cylindrical). Heat transfer consists of convective condition, radiation and heat generation.
View Article and Find Full Text PDFJ Environ Sci Health B
October 2024
This study examined the concentrations of seven heavy metals (Pb, Cu, Zn, Cr, Cd, Ni, and Mn) in the muscle tissue of six commonly consumed fish species (, , and ) from the River Indus in the Mianwali district Pakistan. Samples were collected during both pre-monsoon and post-monsoon seasons to assess the potential human health risks associated with these heavy metals. The levels of metals were measured using atomic absorption spectroscopic analysis.
View Article and Find Full Text PDFThis study examines the levels of heavy metals in polyculture fish (Labeo rohita, Cyprinus carpio, and Catla catla), water, and sediment in Tanda Dam, Kohat, Pakistan, aiming to understand environmental and health risks. Samples of fish, water, and sediment were collected from 3 fish farms, and heavy metal concentrations were measured using a Flame Atomic Absorption Spectrophotometer (AAS). Results reveal that C.
View Article and Find Full Text PDFHeavy metal bioaccumulation in organisms is primarily a result of dietary uptake. The current study examines the concentrations of heavy metals (Pb, Cd, Cr, and Cu) in fish feed, water, sediment, and three fish species (Catla catla, Labeo rohita, and Cyprinus carpio) from different feeding zones in a polyculture pond system. Furthermore, associated human health risks were also evaluated.
View Article and Find Full Text PDFComp Biochem Physiol Part D Genomics Proteomics
March 2024
Triacylglycerol (TAG) is crucial in animal energy storage and membrane biogenesis. The conversion of diacylglycerol (DAG) to triacylglycerol (TAG) is catalyzed by diacylglycerol acyltransferase enzymes (DGATs), which are encoded by genes belonging to two distinct gene families. Although arthropods are known to possess DGATs activities and utilize the glycerol-3-phosphate pathway and MAG pathway for TAG biosynthesis, the sequence characterization and evolutionary history of DGATs in arthropods remains unclear.
View Article and Find Full Text PDFThe mucus layers of fish serve as the main interface between the organism and the environment. They play an important biological and ecological role. The current study focuses on Nile tilapia epidermal mucus reared under different commercial feeds (coded A and B) and environments (biofloc technology and earthen pond systems).
View Article and Find Full Text PDFBiol Trace Elem Res
February 2024
Worldwide, anthropogenic activities are causing the natural environment and aquaculture systems to become heavily contaminated with heavy metals, which can lead to consumer's health problems. In the current study, wild and farmed fish (n = 30) and water samples (n = 6) have been collected from the Chashma barrage and fish farm to assess the heavy metals concentration, i.e.
View Article and Find Full Text PDFFish feed quality is the main determinant of fish flesh quality, so it is important for successful aquaculture. The current study determines the concentration of heavy metals in fish feeds (A and B), water, and their bioaccumulation in gills, liver, and muscle of C. carpio cultured in different environments (biofloc technology and earthen pond systems).
View Article and Find Full Text PDFThis study aimed to assess the Withania coagulans fruit extract's effects on growth and haematological parameters of Labeo rohita. Healthy fish (n = 120) were divided in four groups. Experimental diet was prepared with different extraction of W.
View Article and Find Full Text PDFThe current study aims to assess the cadmium sub-lethal concentration influence on growth and haematological and biochemical parameters of Mystus seenghala. A total of 60 fish of three different length groups (20 each) were collected from Head Qadirabad, Pakistan. The fish were treated to the sub-lethal concentration viz.
View Article and Find Full Text PDFThe aim of the current study was to assess the effect of two different fortified feeds with different concentrations of two important medicinal plants ( and ) on the mucosal immunity of After a dietary intervention, mucus was tested against five pathogenic bacteria (in-vitro), while experimental fish were tested against the ectoparasite (Lernaea) (in-vivo). Our results revealed that all fish groups fed with different concentrations (1, 1.5, and 2%) of had low molecular weight proteins and did not develop any significant signs of parasitic infection, with low mortality rate; whereas the groups that were fed with (particularly with 1% and 2%), including a control group, developed rapid signs of infection with high mortality rate.
View Article and Find Full Text PDFOlive leaves have been used traditionally to improve the immunity against several infections. Current study aimed to examine the effect of fortified feed with olive leaves extract on haematological and biochemical parameters of . Total 400 healthy fish were divided randomly into four groups and were cultured for two months in glass tanks of 250 L water capacity in triplicate.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
March 2018
Objective: The aim of this study was to evaluate the accuracy of “X- ray examination of surgically resected specimen‘‘ in assessing complete local excision (CLE). Materials and Methods: In this retrospective cross sectional study, data were collected for all female breast cancer cases who underwent breast-conserving surgery after needle localization of mammographically visible disease. Males, patients with mammographically invisible disease and cases with benign or inconclusive histopathology, those undergoing modified radical mastectomy and individuals with dense breast parenchyma were excluded.
View Article and Find Full Text PDFJ Coll Physicians Surg Pak
December 2017
Objective: To evaluate the success of ultrasound in post-excision specimen visualization, and negative predictive value of ultrasound for estimation of tumor-free margins using histopathology as the gold standard.
Study Design: Cross-sectional analytical study.
Place And Duration Of Study: The Aga Khan University Hospital, Karachi, Pakistan, from May 2010 till January 2013.
J Coll Physicians Surg Pak
September 2017
The transverse vaginal septum is a rare form of Mullerian duct anomaly, and is a disorder of vertical fusion of Mullerian system with the sinovaginal bulb. Magnetic resonance imaging (MRI)is very useful in the detection, classification and management planning of this rare anomaly. We present two cases of transverse vaginal septum in two patients of different age groups and with different clinical presentations.
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