Developmental Programming and Postnatal Modulations of Muscle Development in Ruminants.

Prenatal and postnatal skeletal muscle development in ruminants is coordinated by interactions between genetic, nutritional, epigenetic, and endocrine factors. This review focuses on the influence of maternal nutrition during gestation on fetal myogenesis, satellite cell dynamics, and myogenic regulatory factors expression, including , , and . Studies in sheep and cattle indicate that nutrient restriction or overnutrition alters muscle fiber number, the cross-sectional area, and the transcriptional regulation of myogenic genes in offspring.

Molecular Detection of Non-Polio Enteroviruses and Emergence of Novel Enterovirus D111 in Stool Samples From Children Reported With Acute Flaccid Paralysis Symptoms During 2021 in Pakistan.

This study explores the molecular detection and genetic diversity of non-polio enteroviruses (NPEVs) reported with symptoms of acute flaccid paralysis (AFP) cases (referring to individual patients) in Pakistan during 2021. A total of 2337 stool samples were analyzed through WHO-recommended intratypic differentiation (ITD) using real-time PCR. Among these, 134 samples detected positive for NPEVs, corresponding to 66 individuals AFP cases.

Interactive Effect of Microplastics and Fungal Pathogen on Antioxidative Mechanism and Fluorescence Activity of Invasive Species .

Microplastics and invasive species, driven by anthropogenic activities, significantly disrupt ecosystems and microbial communities. This study investigated the interactive effects of biodegradable microplastics (polylactic acid, or PLA, and polyhydroxyalkanoates, or PHAs) and the fungal pathogen on the invasive plant . One plant of /pot was cultivated in forest soil amended with 1% (/) microplastics and/or PLA exhibited greater toxicity than PHAs, reducing the plant height, root length, and biomass by 68%, 44%, and 70%, respectively.

Investigating the role of bulk and nano nickel in amelioration of morphophysiology and photosynthetic activity of Triticum aestivum L.

Nickel is a hormetic micronutrient for plants. This study investigates the comparative impact of seed priming with nickel in the form of bulk particles, and green-synthesized nanoparticles fabricated using leaf extract of Berberis baluchistanica, as reducing and capping agent, on germination, phenotypic characteristics, antioxidants, stomata, and photosynthetic activity of two wheat cultivars in a laboratory pot experiment. The synthesis of NiO-NPs was confirmed by using UV-spectrophotometer (peak at 203 nm) and their size observed was 22 nm.

Are we all singing from the same song sheet? Standardizing terminology used in inter-professional telehealth education and practice: a mixed method study.

Background: Telehealth interventions have proven essential in maintaining healthcare delivery during the global pandemic. However, its broader adoption within different healthcare settings has been impacted by inconsistent and non-standardized terminology, which poses challenges to global implementation and stakeholder communication. This article addresses these barriers by analyzing telehealth-related terms and developing a detailed clinical guide to aid inter-professional health educators in adopting standardized terminology, improving clarity, and fostering collaboration.

Withania coagulans-mediated green synthesis of silver nanoparticles: characterization and assessment of their phytochemical, antioxidant, toxicity, and antimicrobial activities.

Background: In this study, we report the biofabrication of silver nanoparticles (Ag-NPs) using aqueous leaf extracts of Withania coagulans, which act as both reducing and capping agents. The goal was to synthesize and characterize the silver nanoparticles and evaluate their biological properties.

Results: The silver nanoparticles were characterized by multiple techniques including UV-visible spectroscopy, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Raman spectroscopy, scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), high-resolution transmission electron microscopy (HRTEM), zeta potential, dynamic light scattering (DLS), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC).

Green-fabricated MnO₂ nanoparticles function as dual nanofertilizers and chromium remediators, enhancing antioxidant pathways, ionomic networks, and physiological resilience in wheat.

This study investigates the potential of green-fabricated manganese dioxide (MnO₂) nanoparticles (NPs) to mitigate chromium (Cr) toxicity in wheat, presenting a novel approach to enhancing ion homeostasis and physiological resilience under Cr stress. Chromium contamination in agricultural soils is a significant concern, severely impacting crop productivity and disrupting the physiological homeostasis of wheat. Chromium exposure compromises nutrient uptake, induces oxidative stress, and impairs plant growth and yield.

Restoring wheat productivity and nutrient balance under cadmium stress through reducing toxicity, metal uptake, and oxidative damage using selenium nanoparticles.

Cadmium (Cd) contamination in soil poses a significant environmental threat, reducing crop yields and compromising food safety. This study investigates the potential of selenium nanoparticles (Se-NPs) synthesized using wheat extract to mitigate Cd toxicity, reduce Cd uptake and mobility, and recover grain nutrient composition in wheat (Triticum aestivum L.).

Durian and Sapodilla Extracts Enhance Chemotherapy Sensitivity and Promote Apoptosis in Triple Negative Breast Cancer Model in Vitro: Systematic Review.

Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with main option for therapeutic is chemotherapy. Natural compounds, such as durian (Durio zibethinus) and sapodilla (Manilkara zapota) extracts, have demonstrated anticancer properties, including apoptosis induction and the potential to overcome chemotherapy resistance.

Objective: This systematic review evaluates the effects of these extracts on TNBC cells, focusing on their ability to enhance chemotherapy sensitivity with induced apoptosis and decreased chemotherapy resistance.

Multi-trait phenotypic modeling through factor analysis and bayesian network learning to develop latent reproductive, body conformational, and carcass-associated traits in admixed beef heifers.

Despite high-throughput and large-scale phenotyping becoming easier, interpretation of such data in cattle production remains challenging due to the complex and highly correlated nature of many traits. Underlying biological traits (UBT) of economic importance are defined by a subset of easy-to-measure traits, leading to challenges in making appropriate selection decisions on them. Research on UBT in beef cattle is limited.

Phytochemical-Mediated Green Synthesis of Silver, Copper, and Ag-Cu Bimetallic Nanoparticles Using Peganum harmala Demonstrating Advanced Catalytic, Antioxidant, and Biomedical Applications.

This study explores the green synthesis of silver (Ag-NPs), copper (Cu-NPs), and silver-copper bimetallic nanoparticles (Ag-Cu Bimetallic NPs) using the leaf extract of Peganum harmala, a sustainable and renewable plant source. This eco-friendly synthesis method avoids hazardous chemicals and minimizes waste, advancing the principles of green nanotechnology. Characterization demonstrated distinct properties; Ag-NPs, Cu-NPs, and Ag-Cu bimetallic NPs exhibited surface plasmon resonance peaks at 425 nm, 555 nm, and 525 nm, respectively, and crystallite sizes of 21.

Mitigating cadmium stress in rice (Oryza sativa L.) using succinic and oxalic acids with focus on cellular integrity and antioxidant responses.

Soil contamination with toxic heavy metals [such as cadmium (Cd)] is becoming a serious global problem due to the rapid development of the social economy. Organic chelating agents such as succinic acid (SA) and oxalic acid (OA) are more efficient, environmentally friendly, and biodegradable compared to inorganic chelating agents and they enhance the solubility, absorption, and stability of metals. To investigate this, we conducted a pot experiment to assess the impact of SA (0.

Application of fertilizers improves cadmium phytoextraction efficiency of Nasturtium officinale R.Br. grown in cadmium-contaminated water.

Increasing toxic metal pollution in the aquatic ecosystem since the industrial revolution produces serious environmental challenges and has raised critical questions of ecological and human health implications. As a typical aquatic plant, Nasturtium officinale (N. officinale) has drawn significant attention due to its remarkable accumulation of heavy metals and other harmful substances from polluted water.

Efficacy of ascorbic acid coated quantum dots in alleviating lead-induced oxidative damage and enhancing growth parameters in rice (Oryza sativa L.) for sustainable cultivation.

Lead (Pb) toxicity impairs the growth, yield, and biochemical traits of rice, making it essential to mitigate Pb stress in soil and restore its growth and production. This study investigated the potential of ascorbic acid-coated quantum dots (AsA-QDs) in alleviating Pb stress in two rice cultivars, Japonica (JP-5) and Indica (Super Basmati), grown in pots under Pb stress (50 mg/kg as lead chloride) with AsA-QD suspensions (50 ppm and 100 ppm) as treatments. The synthesized AsA-QDs were characterized by zeta potential (-14.

Evaluating the potential of in alleviation of aluminium stress in .

Soil contamination with toxic heavy metals [such as aluminum (Al)] is becoming a serious global problem due to the rapid development of the social economy. Although plant growth-promoting rhizo-bacteria (PGPR) are the major protectants to alleviate metal toxicity, the study of these bacteria to ameliorate the toxic effects of Al is limited. Therefore, the present study was conducted to investigate the combined effects of different levels of (5 ppm and 10 ppm) of accession number of MT123456 on plant growth and biomass, photosynthetic pigments, gas exchange attributes, oxidative stress and response of antioxidant compounds (enzymatic and nonenzymatic), and their specific gene expression, sugars, nutritional status of the plant, organic acid exudation pattern and Al accumulation from the different parts of the plants, which was spiked with different levels of Al [0 µM (i.

Influence of maternal nutrition and one-carbon metabolites supplementation on bovine antimicrobial peptides in fetal and maternal tissues.

Introduction: Maternal nutrition during pregnancy critically influences offspring development and immune function. One-carbon metabolites (OCM) are epigenetic modifiers that may modulate antimicrobial peptide (AMP) expression, which is vital for innate immunity. This study investigated the effects of maternal nutrient restriction and OCM supplementation on mRNA expression of AMP in fetal and maternal lung, mammary gland, and small intestine of beef cattle.

analysis of heavy metals and halogenated compounds in reclaimed water using novel electrospray ionization combined with plasma ionization linear ion trap mass spectrometry.

Water scarcity is a global concern that needs addressing through alternative sources. One of the approaches is the use of reclaimed water for irrigation. However, the presence of halogenated compounds and heavy metals in reclaimed water poses significant food safety threats.

Sustainable Development Goals (SDGs): The nexus of fintech and water productivity in 11 BRICS countries.

In the context of a global water crisis, enhancing water productivity is becoming increasingly crucial. While previous research has predominantly addressed technical and policy aspects of water management, the role of fintech in improving water productivity has not been sufficiently explored. This research investigates the impact of fintech on water productivity, considering the moderating effect of education level.

Intergenerational effects of maternal rate of body weight gain on the multi-omics hepatic profiles of bovine fetuses.

Maternal periconceptual nutrition affects the growth trajectory of developing fetuses by modulating gene expression. The regulatory mechanisms and their role in fetal development remain underexplored in livestock models. Herein, we investigated the effects of maternal rate of body weight (BW) gain during early gestation on the DNA methylation, microRNA profiles, and their interaction with the hepatic gene expression in female fetuses.