Untargeted metabolomics reveals the inhibition effect of a high-fat diet on colorectal cancer tumorigenesis in obesity-resistant mice regulating bile acid, glutathione, and glycerophospholipid metabolisms.

The interplay between high fat intake and cancer is complex and multifaceted. Contradictory results exist between obesity, high-fat diet (HFD), and colorectal cancer (CRC), necessitating further research. In this study, we investigated the effect of HFD on tumorigenesis in obesity-resistant and obesity-susceptible mouse models.

Green Tea Epigallocatechin-3-gallate Ameliorates Lipid Accumulation and Obesity-Associated Metabolic Syndrome via Regulating Autophagy and Lipolysis in Preadipocytes and Adipose Tissue.

Previous studies have shown that epigallocatechin-3-gallate (EGCG), the most abundant catechin in green tea, demonstrates promising antiobesity effects. While autophagy mediates obesity via preadipocyte differentiation and lipogenesis, EGCG's potential autophagy-dependent antiobesity mechanism remains unclear. We used 3T3-L1 cells and high-fat-diet (HFD)-fed mice to examine how EGCG inhibits adipogenesis and lipogenesis via autophagy.

Widely targeted metabolomic and KEGG analyses of natural deep eutectic solvent-based saponins extraction from Camellia oleifera Abel.: Effects on composition.

Camellia saponins are important by-products of Camellia Oleifer Abel. processing. In this study, an eco-friendly method based on natural deep eutectic solvents (NaDESs, proline and glycerol at a molar ratio of 2:5) was established to extract saponins from C.

A Novel Ionic Conductive Polyurethane Based on Deep Eutectic Solvent Continuing Traditional Merits.

Artificial intelligence (AI) has become increasingly popular along with the development of the bionic neural system. Ionic conductors play an important role in the AI system due to the ability of bionic sensing and signal transporting. Traditional low-polarity elastomers possess outstanding mechanical strength and stability, such as polyurethane, which is difficult to be directly endowed with ionic conductivity without impairing its properties.

A Method for Identifying the Spatial Range of Mining Disturbance Based on Contribution Quantification and Significance Test.

Identifying the spatial range of mining disturbance on vegetation is of significant importance for the plan of environmental rehabilitation in mining areas. This paper proposes a method to identify the spatial range of mining disturbance (SRMD). First, a non-linear and quantitative relationship between driving factors and fractional vegetation cover (FVC) was constructed by geographically weighted artificial neural network (GWANN).

Exogenous application of jasmonic acid induces volatile emissions in rice and enhances parasitism of Nilaparvata lugens eggs by the parasitoid Anagrus nilaparvatae.

Jasmonate signaling pathway plays an important role in induced plant defense against herbivores and pathogens, including the emission of volatiles that serve as attractants for natural enemies of herbivores. We studied the volatiles emitted from rice plants that were wounded and treated with jasmonic acid (JA) and their effects on the host-searching behavior of the rice brown planthopper, Nilaparvata lugens (Stål), and its mymarid egg parasitoid Anagrus nilaparvatae Pang et Wang. Female adults of N.

[Analysis of ant oil extracted with supercritical CO2 fluid from Polyrhachis vicina by GC-MS].

Objective: To study the optimum extraction parameters and components on ant oil from Polyrhachis vicina.

Method: The optimum condifious for supercritical CO2 fluid extraction (SFE-CO2), were investigated with orthogonal design, GC-MS was applied for analyzing. The components and their contents in the ant oil were analyzed by GC-MS, and the contents of lead, zinc and manganese in the oil were determined by ICP-AES.