Chinese multicenter expert consensus on the diagnosis and treatment of hilar cholangiocarcinoma: 2025 edition.

Hilar cholangiocarcinoma (hCCA) is a malignant tumor originating from the epithelial cells of the bile ducts, and it is characterized by an aggressive nature, complex surgical management, high mortality, and poor prognosis. Despite recent advances in surgical techniques, medical devices, and related technologies, there remains a pressing need to standardize diagnostic and therapeutic pathways to improve treatment outcomes and extend long-term patient survival. To better integrate and refine these standards, this consensus was reached through a national conference held in Changsha, Hunan Province, involving multidisciplinary experts from various regions across China.

From LiCO to LiCO: Understanding Discharge Product Decomposition in Li-CO Batteries.

Rechargeable lithium-carbon dioxide (Li-CO) batteries are promising for CO capture and energy storage. However, the high decomposition potential and sluggish kinetics of the discharge product LiCO limit their practical development. Recent studies have identified LiCO as an alternative with superior electrochemical decomposition properties.

Spatial-temporal evolution, drivers, and pathways of the synergistic effects of digital transformation on pollution and carbon reduction in heavily polluting enterprises.

Under the "dual carbon" goals, heavily polluting enterprises face dual pressures to reduce both pollution and carbon emissions, necessitating the urgent exploration of effective pathways for coordinated emission reductions. This study investigates the potential of digital transformation in enterprises to achieve synergistic emission reductions. First, the entropy method is employed to measure enterprise digitalization and pollutant levels, and the spatial-temporal evolution characteristics of regional coordinated emission reductions are analyzed.

Relationship between chromatin configuration and maturation ability of rat oocytes in vitro and in vivo.

Purpose: Embryo engineering requires a large number of oocytes, which undergo in vitro maturation (IVM). Understanding how to select the best quality oocytes is key to improving IVM efficiency. Oocytes have different germinal vesicle (GV) chromatin configurations, which may explain the heterogeneity in oocyte quality during IVM.

[Retracted] SIRT6 promotes ferroptosis and attenuates glycolysis in pancreatic cancer through regulation of the NF‑κB pathway.

[This retracts the article DOI: 10.3892/etm.2022.

Beyond Catalysts: Exploring Discharge Product Growth and Intrinsic Overpotential in Lithium-Oxygen Batteries.

The lithium-oxygen (Li-O) battery, renowned for its exceptionally high theoretical energy density, is poised to revolutionize next-generation energy storage systems. However, its practical application depends on overcoming several challenges, particularly the high cathode overpotential, which significantly diminishes the battery's energy efficiency and durability. This study delves into the interactions at the cathode surface during oxygen reduction and evolution reactions (ORR/OER), extending the analysis beyond the initial reaction stages to encompass the extensive charge-discharge process.

Malignant rhabdoid tumor of the omentum in an adult male: a case report and literature review.

Malignant rhabdoid tumors (MRTs) are rare tumors with high mortality rates and poor prognoses. MRTs occur mainly in the central nervous system, kidneys, and soft tissues, but rarely in the omentum. MRTs occur more commonly in infants and children and less frequently in adults.

SIRT6 promotes ferroptosis and attenuates glycolysis in pancreatic cancer through regulation of the NF-κB pathway.

Pancreatic cancer (PC) is a malignant tumor with high mortality worldwide. SIRT6 plays versatile roles in human cancers. However, SIRT6 has rarely been studied in PC.

Surgical Strategy and Prognosis of Pancreatic Neuroendocrine Tumors Based on Smart Medical Imaging.

It is imperative to seize the "golden rescue time" and implement new concepts and new skills in modern trauma rescue. Combining with the development background of smart medical image analysis, this topic focuses on surgical strategies and prognostic measures and studies a serious and difficult disease frequently occurring in middle-aged and elderly people: pancreatic neuroendocrine tumors. This article uses the comparative test method and sample collection method to collect the medical records of patients with neuroendocrine tumors diagnosed by pathology from July 2010 to January 2018 in the First Affiliated Hospital of X City and analyze the samples with gender and age.

Computational Insight into Metallated Graphynes as Single Atom Electrocatalysts for Nitrogen Fixation.

The electrochemical nitrogen reduction reaction (NRR) is expected to achieve sustainable ammonia synthesis via direct nitrogen fixation; however, the high-quality catalysts that play a crucial role in the NRR are still lacking. The emerging transition metal-1,3,5-triethynylbenzene (TM-TEB) frameworks offer attractive possibilities in the electrochemical catalysis due to the featured atomic and electronic structures. This work presents a comprehensive first-principles study of the TM-TEB systems for TMs from the first three d-block series and systematically explores their potential applications as NRR electrocatalysts.

Simulation of the pollution abatement behavior of regional metal-related enterprises based on the interactive perspective of industrial agglomerations and emission reduction effects.

A machine learning method was used to process a multiagent information database to study the spatial distribution characteristics of agglomerations of metal-related enterprises and to analyze the spatial and temporal differentiation characteristics of pollution reduction in metal-related enterprises. Based on the spatial distribution of enterprises and a simulation of their pollution reduction behaviors, the layout of 380 enterprises sample is optimized, and the direction of industrial transfer is planned to give full play to the pollution reduction effect of enterprise agglomeration. The results showed that (1) the metal-related enterprises in the Chang-Zhu-Tan urban agglomeration have obvious spatial heterogeneity and are mainly distributed in the district of Changsha, the Qingshuitang Industrial Zone, Liling city and the Qibaoshan Industrial Zone of Liuyang city, while the metal-related enterprises in Shaoshan city, Zhuzhou County and Liling city are scattered.

The thermodynamics and electronic structure analysis of P-doped spinel CoO.

The thermodynamics of phosphorus (P) doping to spinel CoO, for both bulk cases and (100) and (110) surface cases, is studied using first principles calculations. The doping energies of the P atom at different doping sites are carefully calculated and compared. It is shown that P doping at Co sites, at either tetrahedral or octahedral sites, is energetically favorable, while P doping and replacing O atoms are energetically unfavorable.

Interpenetrating graphene network bct-C: a promising anode material for Li ion batteries.

The stable sp-C atoms in graphite enable its excellent structural and electrochemical stability as an anode material for Li-ion battery applications, while the limited Li-storage capacity of graphite also originates from the sp hybridization. Herein, from first-principles calculations, we show that a synergistic effect of sp and sp hybridized C atoms can substantially enhance the Li-storage performance in carbon-based anodes, using bct-C as an example, which is constructed with interconnected graphene layers (sp hybridized C atoms) and the connecting points are composed of sp-C atoms. Charge transfer from sp-C atoms to sp-C atoms has been found, leading to unoccupied electronic states forming around the Fermi level.

First principles study of g-MgN as an anode material for Na-, K-, Mg-, Ca- and Al-ion storage.

Searching for electrode materials for non-lithium metal ion batteries (NLMIBs) is key to the success of NLMIBs. In this work, we investigated the scientific feasibility of using g-MgN, which is a novel 2D graphene-like material, as an anode for non-lithium metal-ions (Na, K, Mg, Ca and Al) batteries based on density functional theory calculations. The sequential adsorption energy, Bader charge, intercalation voltage, energy-storage capacity, electronic conductivity and metal-ion diffusion energy barrier are calculated.

Density functional theory prediction of MgN as a high-performance anode material for Li-ion batteries.

Two dimensional (2D) materials have great potential for application in energy storage due to their unique structural characteristics. Here we propose for the first time a density functional theory study into the scientific feasibility of using g-Mg3N2, which is a novel graphene-like 2D material, as a high-capacity anode material for Li-ion batteries (LIBs). The favorable Li-adsorption geometries and the Li adsorption thermodynamics are explored in detail.

Normal anatomy of urethral sphincter complex in young Chinese males on MRI.

Purpose: In this research, the normal anatomy of urethral sphincter complex in young Chinese males has been studied.

Methods: The sagittal, coronal, and axial T2-weighted non-fat suppressed fast spin-echo images of pelvic cavities of 86 Chinese young males were studied.

Result: Urethral sphincter complex is a cylindrical structure surrounding the urethra and extending vertically from bladder neck to perineal membrane.