Environmental DNA-Based Ecological Risk Assessment of PAHs in Aged Petroleum-Contaminated Soils.

(1) Background: Polycyclic aromatic hydrocarbons (PAHs) are important components of petroleum and pose a serious threat to the soil environment of oil production well sites. Therefore, scientific risk thresholds and ecological risk assessment methods must be established for PAHs in petroleum-contaminated soils. (2) Methods: In this study, based on the environmental DNA (eDNA) method, the soil bacterial community was considered as a receptor to assess the ecological risks of PAH contamination in aged petroleum-polluted soils.

Metastatic INI-1-deficient undifferentiated lung cancer with EGFR 19del mutation identified in pleural effusion: a case report and review of the literature.

INI-1 is a core component of the switch/sucrose-non-fermenting (SWI/SNF) complex, an ATP-dependent chromatin remodeling complex that plays a critical role in DNA repair, transcriptional regulation, and cellular differentiation. Intrathoracic tumors driven by INI-1 inactivation are exceptionally rare. This report presents the first documented case of metastatic INI-1-deficient undifferentiated lung cancer harboring a co-occurring epidermal growth factor receptor (EGFR) exon 19 deletion mutation.

Authentic Inner Compass and Subjective Well-Being Among Chinese Emerging Adults: A Moderated Mediation Model.

Originating from the self-determination theory, the authentic inner compass (AIC) enlightens people about their authentic values, interests, and life aspirations, functioning as an action-guiding schema. Previous studies have examined AIC among adolescents, but its significance for emerging adults is underexplored, especially in less autonomy-oriented cultures (e.g.

Integrated Transcriptomics and Metabolomics Reveal Key Genes and Metabolic Pathway in Flower and Fruit Color Formation of (Bge.) Sok.

Anthocyanins play a pivotal role in determining the color diversity in the flowers and fruits of (Bge.) Sok. This study performed a metabolomic analysis of the flowers and fruits of two varieties differing in pigmentation phenotypes ('Jinou 1' and 'Nongda 5'), and the results indicated that the cyanidin, pelargonidin, paeonidin, and delphinidin were the main substances serving as the primary pigments contributing to their striking chromatic divergence between two varieties.

Reverse‑sequence endoscopic nipple‑sparing mastectomy with direct‑to‑implant breast reconstruction and air inflation adjustment technique in patients with large or severely ptotic breast: a single-center prospective cohort study.

Background: The applicability of reverse-sequence endoscopic nipple-sparing mastectomy (R-E-NSM) with direct-to-implant breast reconstruction (DIBR) is worth exploring in patients with large or severely ptotic breasts (LSPB) who were not recommended or even considered contraindicated in open NSM, conventional endoscopic NSM, and robotic NSM. The study aimed to compare the safety and aesthetic outcomes between patients with LSPB and non-LSPB (NLSPB) undergoing R-E-NSM with DIBR.

Materials And Methods: The single-center prospective cohort study enrolled 562 patients undergoing R-E-NSM and DIBR.

Development of a blocking ELISA employing a VP1-specific monoclonal antibody for the detection of DHAV3 antibodies.

Duck hepatitis A virus (DHAV) causes an acute and severe infectious disease characterized by liver swelling and hemorrhage, predominantly affecting ducklings under three weeks of age. This disease leads to significant economic losses in the duck farming industry. In China, both DHAV1 and DHAV3 are prevalent, with DHAV3 being more dominant.

Metabolomics- and Proteomics-Based Disease Diagnostic Classifier Model for the Prediction and Diagnosis of Colorectal Carcinoma.

Background: Colorectal carcinoma (CRC) is a leading cause of cancer-related deaths globally. Diagnostic biomarkers are essential for risk stratification and early detection, potentially enhancing patient survival. Our study aimed to explore the potential biomarkers of CRC at the protein and metabolic levels.

Metabolomic-Based Assessment of Earthworm () Exposure to Different Petroleum Fractions in Soils.

Petroleum contamination in soil exerts toxic effects on earthworms () through non-polar narcotic mechanisms. However, the specific toxicities of individual petroleum components remain insufficiently understood. This study investigates the effects of four petroleum components-saturated hydrocarbons, aromatic hydrocarbons, resins, and asphaltenes-on earthworms in artificially contaminated soil, utilizing a combination of biochemical biomarker analysis and metabolomics to uncover the underlying molecular mechanisms.

Eyeball descending identification using MRI-based spatial coordinates in thyroid-associated orbitopathy patients with unilateral upper eyelid retraction.

Background: Upper eyelid retraction (UER), the primary symptom of thyroid-associated orbitopathy (TAO), can affect perceived eyeball position. This study aimed to assess relative anatomical positions, and examine changes in eyeball position and related factors in TAO patients with unilateral UER.

Methods: In total, 30 TAO patients with unilateral UER and 67 healthy control participants were included in this retrospective study.

One lung ventilation during thoracoscopic lobectomy alters lung microbiome miversity and composition.

Current research indicates that the lungs are not sterile and maintain their own unique microecological balance, which can be disrupted by mechanical ventilation.One-lung ventilation (OLV) induces ischemia-reperfusion (IR) injury in the non-ventilated lung, a common contributor to acute lung injury during the perioperative period. This study investigates alterations in the pulmonary microbiome following one-lung ventilation during thoracoscopic lobectomy and evaluates the impact of differential microbiota on inflammatory responses.

A splicing variant in EFCAB7 hinders ciliary transport and disrupts cardiac development.

The Tetralogy of Fallot (TOF), the most prevalent form of cyanotic congenital heart disease, stems from abnormal development of the outflow tract during embryogenesis. Despite the crucial role played by primary cilia in heart development, there is currently insufficient evidence to establish a causal relationship between defects in genes related to primary cilia and non-syndromic TOF. Here, we performed Sanger sequencing on 131 Chinese patients diagnosed with TOF and identified a splicing variant (c.

Science tells us that portable air filters reduce infection risk. It's time for public health authorities to make this clear.

Throughout the COVID-19 pandemic, Canadian public health advisors and politicians have shared mixed messages about the utility of portable air filters (PAFs) for mitigating the transmission of airborne infectious diseases. Some public health advisors and decision-makers have also suggested that PAFs are cumbersome or require expert advice. We take this opportunity to review evidence and address myths about PAFs.

Ultrasonographic modeling of lung and diaphragm mechanics: clinical trial of a novel non-invasive method to evaluate pre-operative pulmonary function.

Background: Pre-operative pulmonary function testing (PFT) plays a key role in predicting postoperative complications or functional impairment. However, PFT requires the subject and examiner to cooperate and the results are influenced by both technical and personal factors. In contrast, the use of ultrasound (US) for structural and functional assessments of the lungs and diaphragm is on the rise, as it requires minimal patient cooperation.

Estimating Air Change Rate in Mechanically Ventilated Classrooms Using a Single CO Sensor and Automated Data Segmentation.

With a growing emphasis on indoor air quality (IAQ) in educational environments, CO monitoring in classrooms has become commonplace. CO data can be used to estimate outdoor air change rate (ACH) based on the mass balance principle, which can be further linked to human health, performance, and building energy consumption. This study used a novel machine learning method to automatically segment CO concentration time series data into build-up, equilibrium, and decay periods, and then estimated classroom ACH using the corresponding CO mass balance equations.

Emergency Knowledge Translation, COVID-19 and indoor air: evaluating a virtual ventilation and filtration consultation program for community spaces in Ontario.

Background: An October, 2021 review of Public Health Ontario's COVID-19 guidance for congregate settings such as shelters and long-term care homes demonstrated that this guidance did not include references to ventilation or filtration. In April 2022, an interdisciplinary team with expertise in indoor air quality (IAQ), engineering, epidemiology, community programming and knowledge translation launched a virtual ventilation and filtration consultation program for community spaces in Toronto, Ontario. The program gives people working in community spaces direct access to IAQ experts through 25-min online appointments.

Indoor air quality in subway microenvironments: Pollutant characteristics, adverse health impacts, and population inequity.

Rapidly increasing urbanization in recent decades has elevated the subway as the primary public transportation mode in metropolitan areas. Indoor air quality (IAQ) inside subways is an important factor that influences the health of commuters and subway workers. This review discusses the subway IAQ in different cities worldwide by comparing the sources and abundance of particulate matter (PM and PM) in these environments.

Morphological, anatomical, and transcriptomics analysis reveals the regulatory mechanisms of cassava plant height development.

Background: Cassava is one of three major potato crops and the sixth most important food crop globally. Improving yield remains a primary aim in cassava breeding. Notably, plant height significantly impacts the yield and quality of crops; however, the mechanisms underlying cassava plant height development are yet to be elucidated.

The stratified effects of repetitive transcranial magnetic stimulation in upper limb motor impairment recovery after stroke: a meta-analysis.

Background: The recovery of upper extremity motor impairment after stroke remains a challenging task. The clinical effectiveness of repetitive transcranial magnetic stimulation (rTMS), which is believed to aid in the recovery process, is still uncertain.

Methods: A systematic search was conducted in Medline (Ovid), Cochrane and Embase electronic databases from March 28, 2014, to March 28, 2023.

Companionship goals and marital goal concordance contribute to relationship satisfaction partly through dyadic coping in dating couples.

Background: Marital goals reflect individuals' understanding of the purpose of marriage and could influence the dyadic interactions and satisfaction in intimate relationships. The current study examines how each partner's marital goals and the concordance of marital goals between the partners influence dating couples' relationship satisfaction through dyadic coping.

Method: The sample consisted of 200 heterosexual dating couples from Hong Kong.

Negative interactions and marital satisfaction across adulthood: The moderating role of affect valuation.

Older adults report higher marital satisfaction than younger adults even after negative interactions. The current study examined affect valuation as a potential moderator to explain age-related differences in the relationship between negative interactions and marital satisfaction. We conducted a 14-day daily diary study among 66 heterosexual couples (132 participants) aged from 21 to 80 years.

The role of implicit theories of intelligence and personality in older adults' resilience: cognitive functioning and social participation as two mediators.

Objectives: Resilience during old age reflects the capacity to adapt to changes and challenges associated with normative aging and is an important component of successful aging. Belief in the incremental theory of intelligence and personality could help older adults maintain cognitive functioning and social engagement, which may further contribute to their resilience. The current study investigated how implicit theories of intelligence and personality affected older adults' resilience and examined cognitive functioning and social participation as two mediators.

Transcriptome analysis reveals the effect of propyl gallate on kiwifruit callus formation.

Exploring the potential action mechanisms of reactive oxygen species during the callus inducing, they can activate specific metabolic pathways in explants to regulate callus development. Reactive oxygen species (ROS) play an important role in the regulation of plant growth and development, but the mechanism of their action on plant callus formation remains to be elucidated. To address this question, kiwifruit was selected as the explant for callus induction, and the influence of ROS on callus formation was investigated by introducing propyl gallate (PG) as an antioxidant into the medium used for inducing callus.

Health and equity implications of individual adaptation to air pollution in a changing climate.

Future climate change can cause more days with poor air quality. This could trigger more alerts telling people to stay inside to protect themselves, with potential consequences for health and health equity. Here, we study the change in US air quality alerts over this century due to fine particulate matter (PM), who they may affect, and how they may respond.