[Impact Analysis of Different Buffer Scale Landscape Patterns on Water Quality of the Fourth Drainage Ditch in Ningxia Yellow River Irrigation Area].

Landscape patterns at specific spatial scales can respond to the sources of non-point source pollutants in water bodies and the surface landscape's ability to absorb them. To investigate the influence of landscape patterns on the water quality of the drainage ditch at different circular buffer scales， the fourth drainage ditch of the Ningxia Yellow River Irrigation Area （YDIA） was taken as the research object， and based on the land-use data in 2022 and the dynamic water quality monitoring data of 26 sampling points from 2021 to 2022， five circular buffer scales， including 100， 200， 500， 1 000， and 2 000 m， were set up， and three methods. Landscape pattern analysis， Spearman rank correlation analysis， and redundancy analysis were used to filter the water quality of the drainage ditch.

Peripheral Blood T-Cell Receptor Repertoire Diversity as a Potential Biomarker in the Diagnosis and Treatment Evaluation of Colorectal and Lung Cancers: A Prospective Observational Study.

Background: T-cell receptor (TCR) diversity 50 (D50) values could assess peripheral blood (PB) TCR diversity and immunity. This study aimed to evaluate the potential D50 value in the diagnosis and treatment evaluation of colorectal cancer (CRC) and nonsmall-cell lung cancer (NSCLC).

Methods: This prospective observational study enrolled patients with CRC, benign colorectal disease (BCD), NSCLC, or benign nodule controls (BNC) and healthy donors (HD) at Yunnan Cancer Hospital between January 2021 and June 2022.

[Prediction of Spatial Distribution of Cation Exchange in Agricultural Soils Based on Machine Learning].

Cation exchange capacity （CEC） reflects the ability of soil to sequester exchangeable cations and is an important indicator of the fertility and environmental quality of agricultural soils. The indoor titration method for determining soil cation exchange is expensive and cumbersome. To this end, 565 soil samples from the 0-20 cm plough layer were collected from farmland in Ningxia, and the parameters of soil pH, organic carbon, and mechanical composition were determined.

The genomic consequences and persistence of sociality in spiders.

In cooperatively breeding social animals, a few individuals account for all reproduction. In some taxa, sociality is accompanied by a transition from outcrossing to inbreeding. In concert, these traits reduce effective population size, potentially rendering transitions to sociality "evolutionarily dead-ends.

Mechanisms of gut homeostasis regulating Th17/Treg cell balance in PMOP.

Postmenopausal osteoporosis (PMOP) is a metabolic bone disease driven by estrogen deficiency, primarily manifesting as reduced bone mass and heightened fracture risk. Its development is intricately linked to the balance between Th17 and Treg cells. Recent studies have highlighted the significant role of gut homeostasis in PMOP.

[Progress in research on mRNA therapeutics for the treatment of genetic diseases].

In recent years, mRNA drugs have shown a great potential for the treatment of genetic diseases and attracted the attention of many researchers. This article has reviewed the advance in the research of mRNA drugs for the treatment of genetic diseases over the past 30 years, including their mechanisms of action and structure design, with a focus on their advantages as alternative therapies such as high specificity, low dosage, and sustained expression. Meanwhile, challenges for the effective delivery and storage methods for the mRNA drugs are discussed, with an aim to provide guidance for subsequent researches.

Association between small nucleolar RNA host gene expression and survival outcome of colorectal cancer patients: A meta-analysis based on PRISMA and bioinformatics analysis.

Introduction: Growing evidence shows that long non-coding RNA small nucleolar RNA host genes (lncRNA SNHGs) enact an pivotal regulatory roles in the shorter survival outcome of colorectal cancer (CRC). However, no research has systematically evaluated the correlation among lncRNA SNHGs expression and survival outcome of CRC. This research indented to screen whether exist potential prognostic effect of lncRNA SNHGs in CRC patientss using comprehensive review and meta-analysis.

Population genomics of the Viking world.

The maritime expansion of Scandinavian populations during the Viking Age (about AD 750-1050) was a far-flung transformation in world history. Here we sequenced the genomes of 442 humans from archaeological sites across Europe and Greenland (to a median depth of about 1×) to understand the global influence of this expansion. We find the Viking period involved gene flow into Scandinavia from the south and east.

MicroRNA-182 promoted esophageal squamous cell carcinoma cell growth and metastasis via targeting YWHAG.

Purpose: To study the functioning mode of miR-182 on esophageal squamous cell carcinoma (ESCC) cell growth and metastasis and provide therapeutic targets for ESCC.

Methods: miR-182 expression level in ESCC cell lines was examined by quantitative real-time polymerase chain reaction (qRT-PCR). Using miR-182 inhibitor, we analyzed the effects of miR-182 down-expression on cell proliferation, invasion, cell apoptosis and cell cycle.

Effects of Icaritin on the physiological activities of esophageal cancer stem cells.

Icaritin is a compound extracted from herb, recent study have found it is able to influence the activity of various types of cancer. Our aim was to investigate the effects of Icaritin on the physiological activities of esophageal cancer stem cells (CSCs). In this study, esophageal cancer cells were cultured and CD133 positive esophageal CSCs were sorted by flow cytometry.

[Application of VSD in 6 Cases of Postoperative Infection -A Clinical Experience Sharing].

Background: Surgical site infection is one of the common postoperative complications of thoracic surgery, and its harm is related to infection degree and location. Light causes local pain, prolonged hospitalization and increased cost. Severe infection can lead to severe infection, even septic shock and life-threatening.

ZnO Film Bulk Acoustic Resonator for the Kinetics Study of Human Blood Coagulation.

Miniaturized and rapid blood coagulation assay technologies are critical in many clinical settings. In this paper, we present a ZnO film bulk acoustic resonator for the kinetic analysis of human blood coagulation. The resonator operated in thickness shear resonance mode at 1.

Micro-electromechanical film bulk acoustic sensor for plasma and whole blood coagulation monitoring.

Monitoring blood coagulation is an important issue in the surgeries and the treatment of cardiovascular diseases. In this work, we reported a novel strategy for the blood coagulation monitoring based on a micro-electromechanical film bulk acoustic resonator. The resonator was excited by a lateral electric field and operated under the shear mode with a frequency of 1.

Synthesis and nonlinear optical properties in the near-IR range of stilbazolium dyes.

A series of stilbazolium salts based on donor-π-acceptor (D-π-A) structure have been synthesized and fully characterized. Photophysical properties including linear absorption, one-photon excited fluorescence (OPEF), two-photon absorption (2PA) properties were systematically investigated. The results suggest that increasing electron-releasing character of the terminal group leads to a more pronounced donor-to-acceptor intramolecular charge transfer (ICT).