Personalized sleep-aiding music intervention for insomnia: A closed-loop neurofeedback approach.

Background: Insomnia is a common sleep disorder that severely impacts health and quality of life. Although music therapy is a widely used non-pharmacological treatment for sleep improvement, its lack of personalization limits its effectiveness.

Methods: We proposed a novel EEG neurofeedback intervention for sleep-aiding music therapy.

Laser-Driven microjet via metal foil ablation.

This article introduces a novel approach to transdermal drug delivery using a laser-driven microjet device. By employing laser ablation on thin metal foils, plasma jets are generated, which in turn induce deformation in a silicone membrane, resulting in sufficient pressure to propel liquid jets for transdermal drug delivery. Aluminum and copper foils, which are closely adhered to the silicone membrane, undergo laser treatment with varying energy densities using a nanosecond Nd: YAG laser.

Invisible threat: Marine suspended particles mediate delayed decay of antibiotic resistome in coastal effluents.

Suspended particles are recognized as hotspots of antibiotic resistance genes (ARGs) in coastal waters. However, the dynamics of ARGs associated with suspended particles during sewage discharge into coastal environments remain poorly understood. This study simulated sewage influx into coastal waters using microcosms to investigate the decay dynamics of particle-associated (PA) and free-living (FL) ARGs.

Corrigendum: A lag bloom pattern of phytoplankton after freshwater input events revealed by daily samples during summer in Qinhuangdao coastal water, China.

[This corrects the article DOI: 10.3389/fmicb.2024.

Effect of long-stranded non-coding RNA-BANCR on the progression of thyroid papillary carcinoma and its mechanism.

Objective: This study aims to investigate the role of BRAF-activated long non-coding RNA (BANCR) in papillary thyroid carcinoma (PTC) progression and its association with clinical and molecular characteristics.

Methods: Sixteen PTC patients were stratified into four groups (PTC, HT, HT-LNM, and PTC-LNM) based on cervical lymph node metastasis and concurrent Hashimoto's thyroiditis (HT) to explore BANCR expression and its relationship with immune-related factors and tumor microenvironment (TME). Functional assays, including Transwell invasion, colony formation, and CCK8 were performed to evaluate the biological effects of BANCR in PTC cell lines.

Biobased hydrophobic liquid mulch film from soybean oil and starch for enhanced terraced field cultivation.

Terraced agriculture faces soil loss during rainstorms leading to natural disasters and crop growth impediments. This study describes a novel biobased hydrophobic liquid mulch film comprised of waste soybean oil, starch, and acrylate monomers that can be used to enhance terraced field cultivation. The novel film, optimized at a 3:7 soybean oil to acrylate monomers ratio, exhibited superior spray ability, reduced wicking, and excellent film formation, which are crucial for its effectiveness as a water erosion barrier.

Flexible Microfluidic Strain Sensor Made with Poly(3,4-ethylenedioxythiophene):polystyrenesulfonate-MXene-Au Nanocomposites for Monitoring Physiological Signals.

Flexible strain sensors have been widely used in wearable electronics. However, the fabrication of flexible strain sensors with a large strain detection range, high sensitivity, and negligible hysteresis remains a formidable challenge, even after enormous advancements in the field. Herein, a flexible microfluidic strain sensor was fabricated by filling poly(3,4-ethylenedioxythiophene):polystyrenesulfonate-MXene-gold (PEDOT:PSS-MXene-Au) nanocomposites into microchannels in an elastic matrix.

Sleep-aiding music therapy for insomnia: Exploring EEG functional connectivity of sleep-related attentional bias.

Study Objectives: This study aimed to investigate the relationship between sleep-aiding music and sleep-related attentional bias based on electroencephalography (EEG) functional connectivity (FC) in patients with insomnia disorder (ID), to evaluate the effectiveness of music in aiding sleep.

Method: This study included 30 participants, comprising 15 patients with ID and 15 healthy controls (HCs). Six types of music were selected for sleep aid, and a dot-probe task based on sleep-related attentional bias was utilized to collect behavioral and EEG data.

A lag bloom pattern of phytoplankton after freshwater input events revealed by daily samples during summer in Qinhuangdao coastal water, China.

Phytoplankton blooms have become a global concern due to their negative impacts on public health, aquaculture, tourism, and the economic stability of coastal regions. Therefore, elucidating the shifts in phytoplankton community structure and abundance, as well as their environmental drivers, is crucial. However, existing studies often fail to capture the detailed dynamics of phytoplankton blooms and their environmental triggers due to low temporal observation resolution.

Fine Structure and Electrochemical Performance Investigations of Spherical LiMnFePO/C Cathode Material Synthesized via a Spray-Drying Route at Various Calcination Temperatures.

LiMnFePO/C is characterized by excellent multiplicative performance and high operating voltage, and as a type of cathode material, it has a high electronic conductivity and thus has received much attention. In this paper, carbon-coated LiMnFePO/C was synthesized using glucose + PEG2000 as the carbon source by wet sanding and spray-drying. The experimental results show that the use of sanding and the spray-drying method can make the particle size distribution of LiMnFePO/C powder more uniform.

Interaction of BANCR in the relationship between Hashimoto's thyroiditis and papillary thyroid carcinoma expression patterns and possible molecular mechanisms.

Background: Previous studies have established a connection between Hashimoto's thyroiditis (HT) and an increased risk of papillary thyroid carcinoma (PTC). However, the molecular mechanisms driving this association are not well understood. The long non-coding RNA (lncRNA) BRAF-activated non-coding RNA (BANCR) has been implicated in various cancers, suggesting a potential role in the HT-PTC linkage.

The longitudinal associations between perceived importance of the internet and depressive symptoms among a sample of Chinese adults.

Objective: The aim of this study is to examine the extent to which individuals' cognitive evaluation of the importance of the Internet is associated with depressive symptoms, and in what ways.

Methods: This study utilized a sample of 4,100 participants from the fourth (2016), fifth (2018), and sixth (2020) waves of the China Family Panel Studies. Structural equation modeling was employed for data analysis.

DUSP28 promotes cell proliferation, migration, and invasion by Akt/β-catenin/Slug axis in breast cancer.

Background:  Breast cancer (BCa) has been the most commonly diagnosed cancer worldwide and the leading cause of cancer-related death. Dual-specificity phosphatase 28 (DUSP28) is associated with various cancer progression, but its function and mechanism in breast cancer remain unclear.

Methods:  DUSP28 level was identified by quantitative real-time polymerase chain reaction (qRT-PCR) and western blot assays.

Pan-cancer analysis of the angiotensin II receptor-associated protein as a prognostic and immunological gene predicting immunotherapy responses in pan-cancer.

Understanding interior molecular mechanisms of tumorigenesis and cancer progression contributes to antitumor treatments. The angiotensin II receptor-associated protein (AGTRAP) has been confirmed to be related with metabolic products in metabolic diseases and can drive the progression of hepatocellular carcinoma and colon carcinoma. However, functions of AGTRAP in other kinds of cancers are unclear, and a pan-cancer analysis of AGTRAP has not been carried out.

The effects of acetamiprid multigeneration stress on metabolism and physiology of Aphis glycines Matsumura (Hemiptera: Aphididae).

Aphis glycines Matsumura (Hemiptera: Aphididae) is a major soybean pest that often poses a serious threat to soybean production. In this study, we checked the effects of acetamiprid on redox, energy metabolism, and hormone expression in A. glycines.

The Application Value of the Central Lymph Node Metastasis Risk Assessment Model in Papillary Thyroid Microcarcinoma of Stage cN0: A Study of 828 Patients.

Background: The aim of this study is to build a risk assessment system for central lymph node metastasis (CLNM) in papillary thyroid microcarcinoma (PTMC) of stage cN0 and to explore its application value in clinical practice.

Methods: A total of 500 patients with PTMC who underwent thyroid operation from 2013 to 2015 in Ningbo First Hospital were selected as the model group. Independent risk factors related to CLNM in PTMC were analyzed and determined, and a risk assessment system for CLNM was preliminarily established.

Tumor microenvironment-related multigene prognostic prediction model for breast cancer.

Background: Breast cancer is an invasive disease with complex molecular mechanisms. Prognosis-related biomarkers are still urgently needed to predict outcomes of breast cancer patients.

Methods: Original data were download from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO).

Effects of Acetamiprid at Low and Median Lethal Concentrations on the Development and Reproduction of the Soybean Aphid .

The soybean aphid Matsumura (Hemiptera: Aphididae) is a major pest of soybean and poses a serious threat to soybean production. Studies on the effect of acetamiprid on the life table parameters of , provide important information for the effective management of this pest. We found that exposure to acetamiprid at LC significantly extended the mean generation time, adult pre-reproductive period, and total pre-reproduction period compared with the control, whereas exposure to acetamiprid at LC significantly shortened these periods.

Suspended particles are hotspots for pathogen-related bacteria and ARGs in coastal beach waters of northern China.

Marine suspended particles are unique micro-habitats for diverse microbes and also hotspots of microbially metabolic activities. However, the association of bacterial pathogens, especially those carrying antibiotic resistance genes (ARGs), with these particles remain largely unknown in coastal habitats. This study investigated the distribution of pathogen-related bacteria and ARGs in particle-associated (PA) and free-living (FL) fractions of samples collected at three coastal beaches using NextGen sequencing and qPCR.

DNA N6-Methyladenine (6mA) Modification Regulates Drug Resistance in Triple Negative Breast Cancer.

Triple negative breast cancer (TNBC) is a subtype of breast cancer with strong aggressiveness and poor clinical treatment effect, accounting for about 10-20% of breast cancer cases. N(6)-methyldeoxyadenosine (6mA) is the most conservative DNA modification in prokaryotes and eukaryotes. It is widely found in bacteria and has such functions as DNA mismatch repair, chromosome separation and virulence regulation.

A novel ε-polylysine-modified microcrystalline cellulose based antibacterial hydrogel for removal of heavy metal.

A new type of double-network hydrogel, cross-linked with microcrystalline cellulose grafted with ε-polylysine (MCC-PL) and N,N-methylene bisacrylamide/acrylic acid, was synthesised to efficiently inhibit bacterial proliferation and remove heavy metals. The physicochemical properties of the MCC-PL hydrogel (MCC-PLH) were characterised using scanning electronic microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, and differential thermogravimetric analysis. The adsorption results showed that the optimal adsorption conditions were temperature of 313 K at pH of 5 and 6 of Pb and Cu, respectively.

A Combined Measurement Method for Large-Size Aerospace Components.

Automated and high-accuracy three-dimensional (3D) shape measurement is required in quality control of large-size components for the aerospace industry. To eliminate the contradiction between global measurement and local precision measurement control in 3D digitalization for the key local features of the large-size components, a combined measurement method is proposed, including a 3D scanner, a laser tracker, and an industrial robot used as an orienting device, to achieve high-accuracy measurement. As for improving the overall measurement accuracy, an accurate calibration method based on coordinate optimization of common points (COCP) and coordinate optimization of global control points (COGP) is proposed to determine the coordinate systems.

The Effect of Acute Erythromycin Exposure on the Swimming Ability of Zebrafish () and Medaka ().

Erythromycin is a widely used antibiotic, and erythromycin contamination may pose a threat to aquatic organisms. However, little is known about the adverse effects of erythromycin on swimming ability. To quantify erythromycin-induced damage to fish swimming ability, and were acutely exposed to erythromycin.