Publications by authors named "Francis D Pope"

Air pollution is the leading environmental risk to public health demanding urgent action. While air quality monitoring provides crucial insights into pollution levels, source apportionment (SA) is essential for identifying pollution sources and informing targeted solutions. However, SA remains underutilized, primarily due to the high costs of data collection.

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Recent evidence suggests short-term exposure to particulate matter (PM) air pollution can impact brain function after a delay period. It is unknown whether effects are predominantly due to the olfactory or lung-brain pathways. In this study 26 adults (M = 27.

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The rapid development of low-cost sensors provides the opportunity to greatly advance the scope and extent of monitoring of indoor air pollution. In this study, calibrated particle matter (PM) sensors and a non-negative matrix factorisation (NMF) source apportionment technique are used to investigate PM concentrations and source contributions across three households in an urban residential area. The NMF is applied to combined data from all houses to generate source profiles that can be used to understand how PM source characteristics are similar or differ between different households in the same urban area.

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Globally, the transport sector is a major contributor to air pollution. Currently, in the UK, vehicle emissions contribute significant amounts of nitrogen oxide (NOx) and particulate matter (PM) pollution in urban areas. Low-emission-zone policies have been used as an intervention to tackle air pollution, and in this context, the UK launched the Low-Traffic Neighbourhood scheme.

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Currently, methodologies for the identification and apportionment of air pollution sources are not widely applied due to their high cost. We present a new approach, combining mobile measurements from multiple sensors collected from the daily walks of citizen scientists, in a high population density area of Birmingham, UK. The methodology successfully pinpoints the different sources affecting the local air quality in the area using only a handful of measurements.

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Most fine ambient particulate matter (PM)-based epidemiological models use globalized concentration-response (CR) functions assuming that the toxicity of PM is solely mass-dependent without considering its chemical composition. Although oxidative potential (OP) has emerged as an alternate metric of PM toxicity, the association between PM mass and OP on a large spatial extent has not been investigated. In this study, we evaluate this relationship using 385 PM samples collected from 14 different sites across 4 different continents and using 5 different OP (and cytotoxicity) endpoints.

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Conventional techniques for monitoring pollen currently have significant limitations in terms of labour, cost and the spatiotemporal resolution that can be achieved. Pollen monitoring networks across the world are generally sparse and are not able to fully represent the detailed characteristics of airborne pollen. There are few studies that observe concentrations on a local scale, and even fewer that do so in ecologically rich rural areas and close to emitting sources.

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Over the past decade, our understanding of the impact of air pollution on short- and long-term population health has advanced considerably, focusing on adverse effects on cardiovascular and respiratory systems. There is, however, increasing evidence that air pollution exposures affect cognitive function, particularly in susceptible groups. Our study seeks to assess and hazard rank the cognitive effects of prevalent indoor and outdoor pollutants through a single-centre investigation on the cognitive functioning of healthy human volunteers aged 50 and above with a familial predisposition to dementia.

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Telematics data, primarily collected from on-board vehicle devices (OBDs), has been utilised in this study to generate a thorough understanding of driving behaviour. The urban case study area is the large metropolitan region of the West Midlands, UK, but the approach is generalizable and translatable to other global urban regions. The new approach of GeoSpatial and Temporal Mapping of Urban Mobility (GeoSTMUM) is used to convert telematics data into driving metrics, including the relative time the vehicle fleet spends idling, cruising, accelerating, and decelerating.

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Objectives: The study aims to investigate the short-term associations between exposure to ambient air pollution (nitrogen dioxide (NO), particulate matter pollution-particles with diameter<2.5 µm (PM) and PM) and incidence of asthma hospital admissions among adults, in Oxford, UK.

Design: Retrospective time-series study.

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Here, we introduce Traffic Ear, an acoustic sensor pack that determines the engine noise of each passing vehicle without interrupting traffic flow. The device consists of an array of microphones combined with a computer vision camera. The class and speed of passing vehicles were estimated using sound wave analysis, image processing, and machine learning algorithms.

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Pollen is a major issue globally, causing as much as 40 % of the population to suffer from hay fever and other allergic conditions. Current techniques for monitoring pollen are either laborious and slow, or expensive, thus alternative methods are needed to provide timely and more localised information on airborne pollen concentrations. We have demonstrated previously that low-cost Optical Particle Counter (OPC) sensors can be used to estimate pollen concentrations when machine learning methods are used to process the data and learn the relationships between OPC output data and conventionally measured pollen concentrations.

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In this study, we use the approach of geospatial and temporal (GeoST) mapping of urban mobility to evaluate the speed-time-acceleration profile (dynamic status) of passenger cars. We then use a pre-developed model, fleet composition and real-world emission factor (EF) datasets to translate vehicles dynamics status into real-urban fuel consumption (FC) and exhaustive (CO and NO) emissions with high spatial (15 m) and temporal (2 h) resolutions. Road transport in the West Midlands, UK, for 2016 and 2018 is the spatial and temporal scope of this study.

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Emergency responses to the COVID-19 pandemic led to major changes in travel behaviours and economic activities with arising impacts upon urban air quality. To date, these air quality changes associated with lockdown measures have typically been assessed using limited city-level regulatory monitoring data, however, low-cost air quality sensors provide capabilities to assess changes across multiple locations at higher spatial-temporal resolution, thereby generating insights relevant for future air quality interventions. The aim of this study was to utilise high-spatial resolution air quality information utilising data arising from a validated (using a random forest field calibration) network of 15 low-cost air quality sensors within Oxford, UK to monitor the impacts of multiple COVID-19 public heath restrictions upon particulate matter concentrations (PM, PM) from January 2020 to September 2021.

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Air quality is one of the most important factors in public health. While outdoor air quality is widely studied, the indoor environment has been less scrutinised, even though time spent indoors is typically much greater than outdoors. The emergence of low-cost sensors can help assess indoor air quality.

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Pollen allergies affect a significant proportion of the global population, and this is expected to worsen in years to come. There is demand for the development of automated pollen monitoring systems. Low-cost Optical Particle Counters (OPCs) measure particulate matter and have attractive advantages of real-time high time resolution data and affordable costs.

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To benefit allergy patients and the medical practitioners, pollen information should be available in both a reliable and timely manner; the latter is only recently possible due to automatic monitoring. To evaluate the performance of all currently available automatic instruments, an international intercomparison campaign was jointly organised by the EUMETNET AutoPollen Programme and the ADOPT COST Action in Munich, Germany (March-July 2021). The automatic systems (hardware plus identification algorithms) were compared with manual Hirst-type traps.

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It is often assumed that a small proportion of a given vehicle fleet produces a disproportionate amount of air pollution emissions. If true, policy actions to target the highly polluting section of the fleet could lead to significant improvements in air quality. In this paper, high-emitter vehicle subsets are defined and their contributions to the total fleet emission are assessed.

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In 2019, a domestic raw coal ban (RCB) was introduced in Ulaanbaatar, Mongolia. Coal-briquettes have since been promoted in Ger district households, however implications for carbon monoxide (CO) exposure remains uncertain. We obtained 48-hour indoor CO concentrations in 23 Ger district households and compared these to 10 raw-coal households.

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Background: Emerging research suggests exposure to high levels of air pollution at critical points in the life-course is detrimental to brain health, including cognitive decline and dementia. Social determinants play a significant role, including socio-economic deprivation, environmental factors and heightened health and social inequalities. Policies have been proposed more generally, but their benefits for brain health have yet to be fully explored.

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The short- and long-term impacts of air pollution on human health are well documented and include cardiovascular, neurological, immune system and developmental damage. Additionally, the irritant qualities of air pollutants can cause respiratory and cardiovascular distress. This can be heightened during exercise and especially so for those with respiratory conditions such as asthma.

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Background: Smoke from solid biomass cooking is often stated to reduce household mosquito levels and, therefore, malarial transmission. However, household air pollution (HAP) from solid biomass cooking is estimated to be responsible for 1.67 times more deaths in children aged under 5 years compared to malaria globally.

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Sulfuric acid is shown to form a core-shell particle on a micron-sized, optically-trapped spherical silica bead. The refractive indices of the silica and sulfuric acid, along with the shell thickness and bead radius were determined by reproducing Mie scattered optical white light as a function of wavelength in Mie spectroscopy. Micron-sized silica aerosols (silica beads were used as a proxy for atmospheric silica minerals) were levitated in a mist of sulfuric acid particles; continuous collection of Mie spectra throughout the collision of sulfuric acid aerosols with the optically trapped silica aerosol demonstrated that the resulting aerosol particle had a core-shell morphology.

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Interventions to reduce household air pollution (HAP) are key to reducing associated morbidity and mortality in low- and middle- income countries (LMICs); especially among pregnant women and young children. This systematic review aims to determine the effectiveness of interventions aimed to reduce HAP exposure associated with domestic solid biomass fuel combustion, compared to usual cooking practices, for improving health outcomes in pregnant women and children under five in LMIC settings. A systematic review and meta-analysis was undertaken with searches undertaken in MEDLINE, EMBASE, CENTRAL, GIM, ClinicalTrials.

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