Atomic-scale 3D structural dynamics and functional degradation of Pt alloy nanocatalysts during the oxygen reduction reaction.

Pt-based electrocatalysts are the primary choice for fuel cells due to their superior oxygen reduction reaction (ORR) activity. To enhance ORR performance and durability, extensive studies have investigated transition metal alloying, doping, and shape control to optimize the three key governing factors for ORR: geometry, local chemistry, and strain of their surface and subsurface. However, systematic optimization remains incomplete, as it requires an atomic-scale understanding of these factors and their dynamics over potential cycling, as well as their relationship to ORR activity.

Drainage-only strategy on weekend for endoscopic retrograde cholangiopancreatography on the risk of procedure-related adverse events: a prospective observational study.

Background: The feasibility of performing complete endoscopic retrograde cholangiopancreatography (ERCP) for acute cholangitis during weekends or holidays remains controversial due to concerns over increased risks of adverse events (AEs) in off-hour procedures.

Objectives: To evaluate whether weekend drainage-only ERCP affects the incidence of AEs compared to standard weekday ERCP, and to identify risk factors for post-ERCP pancreatitis (PEP).

Design: Prospective observational study.

Preliminary feasibility study of a novel spiral-designed plastic stent for endoscopic management of malignant hilar biliary obstruction: a multicenter prospective study (with video).

Background And Aims: Plastic stents (PSs) are widely used for palliative drainage in patients with malignant hilar obstruction (MHO); however, their clinical utility is often limited by their short duration of patency, occlusion, and the risk of migration. This study aimed to evaluate the feasibility, safety, and clinical efficacy of a newly designed Twist stent (Taewoong Medical Co, Ltd, Goyang, South Korea) PS, specifically designed to enhance anchoring and prolong patency during endoscopic MHO treatment.

Methods: This prospective study enrolled 32 patients with MHO who underwent endoscopic retrograde cholangiopancreatography with placement of an 8.

Mandibular metastasis of papillary thyroid carcinoma: a case report and systematic literature review.

In this paper, we systematically review the literature on papillary thyroid carcinoma (PTC) metastasis to the mandible. This is a rare oc-currence, especially in young, asymptomatic patients. We propose appropriate surgical and adjuvant therapy guidelines based on our findings.

Toward a dynamic understanding of work-family boundary management: A control theory perspective.

Boundary theory posits boundary management tactics as specific behaviors. Yet, little is known about whether and why individuals use these tactics variably. Incorporating control theory and boundary theory, we conceptualized boundary management tactics intended to segment work from family (BMT) as dynamic, goal-directed behaviors adopted in response to a perceived work-family discrepancy (i.

Anti-Hair Loss Effect of Veratric Acid on Dermal Papilla Cells.

The activation of hair follicle dermal papilla cells (HFDPCs), a critical target of hair loss relief, can be achieved through the upregulation of proliferation, the stimulation of hair inducibility, and the inhibition of cellular senescence. Veratric acid (VA) is a major benzoic acid found in fruits and vegetables. The biological activity of VA on HFDPCs remains to be elucidated.

Is 'me-time' selfish?: Daily vitality crossover in dual-earner couples.

This multisource daily diary study examined the recovery outcomes of working mothers' time spent for the self (i.e. me-time) and whether the benefits crossover to their husbands.

Anti-skin aging effects of Gosori liquor lees extract by regulating interactions between senescent fibroblasts and adipose-derived stem cells.

When cellular ageing is accelerated by various extrinsic/endogenous stimuli, regenerative function deteriorates, and enriched secretomes, such as the senescence-associated secretory phenotype (SASP), contribute to chronic inflammation and cause matrix degeneration. SASPs from senescent fibroblasts exacerbate cellular senescence via autocrine signalling and also accelerate skin ageing through the induction of neighbouring cell senescence via paracrine signalling. The interaction between dermis fibroblasts and their neighbours, adipose-derived stem cells (ADSCs) in the hypodermis, which lies deep in the dermis, is a potential target for skin ageing.

Prospective validation and revision of predictive models for post-ERCP pancreatitis: focus on procedure-related factors and a novel risk stratification approach.

Introduction: Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common serious adverse event after endoscopic retrograde cholangiopancreatography (ERCP). Although retrospective models to predict PEP have shown promise, their real-world applicability remains uncertain. Thus, we used prospectively derived cohort data to validate current prediction models.

Candida tropicalis Liver Abscess in an Immunocompromised Patient With Pancreatic Head Cancer on 68 Ga-FAPI PET/CT.

Candida infections have become a growing concern to the immunocompromised patients with cancer. We report a case of liver abscess causing Candida tropicalis candidemia in an immunocompromised patient with pancreatic head cancer on 68 Ga-FAPI PET/CT. A 77-year-old man had a history of 10-year duration of uncontrolled diabetes, the presence of neutropenia, immunocompromised condition, and the progression of pancreatic cancer despite the 14 cycles of chemotherapy and palliative radiotherapy.

Identification of risk factors associated with post-ERCP pancreatitis in patients with easy cannulation: a prospective multicenter observational study (with videos).

Background And Aims: Difficult biliary cannulation is an independent risk factor for post-ERCP pancreatitis (PEP); however, there is a noticeable lack of studies focusing on the incidence and risk factors of PEP among patients undergoing easy cannulation. Therefore, we systematically investigated the risk factors for PEP in patients who underwent easy cannulation.

Methods: We prospectively enrolled patients with naive major papillae who underwent diagnostic or therapeutic ERCP between June 2018 and June 2023.

Structural and Compositional Optimization of Fe-Co-Ni Ternary Amorphous Electrocatalysts for Efficient Oxygen Evolution in Anion Exchange Membrane Water Electrolysis.

Anion exchange membrane water electrolysis (AEMWE) offers a sustainable path for hydrogen production with advantages such as high current density, dynamic responsiveness, and low-cost electrocatalysts. However, the development of efficient and durable oxygen evolution reaction (OER) electrocatalysts under operating conditions is crucial for achieving the AEMWE. This study systematically investigated Fe-Co-Ni ternary amorphous electrocatalysts for the OER in AEMWE through a comprehensive material library system comprising 21 composition series.

Heterogeneous Structure of Ni-Mo Nanoalloys Decorated on MoO for an Efficient Hydrogen Evolution Reaction Using Hydrogen Spillover.

Herein, a heterogeneous structure of Ni-Mo catalyst comprising NiMo nanoalloys decorated on a MoO matrix via electrodeposition is introduced. This catalyst exhibits remarkable hydrogen evolution reaction (HER) activity across a range of pH conditions. The heterogeneous Ni-Mo catalyst showed low overpotentials only of 24 and 86, 21 and 60, and 37 and 168 mV to produce a current density of 10 and 100 mA cm (η and η) in alkaline, acidic, and neutral media, respectively, which represents one of the most active catalysts for the HER.

Intracellular infection of Cutibacterium acnes in macrophages of extensive peri-implantitis lesions: A clinical case series.

Cutibacterium acnes is a facultative anaerobic, gram-positive rod, and a commensal bacterium of the body surface including oral cavity. A causal relationship between C. acnes and chronic granulomatous diseases, such as sarcoidosis and orthopedic implant-associated infections, has been previously reported.

Synchronous occurrence of oral squamous cell carcinoma and Warthin's tumor: systematic review and case report.

We systematically reviewed the literature on the co-occurrence of squamous cell carcinoma (SCC) and Warthin's tumor (WT), thought to be quite rare, to help reduce misdiagnosis and improve treatment planning. For this systematic review, we searched for articles in the Web of Science and PubMed databases, analyzed relevant studies for forward and backward citations, and identified only articles reporting on the "co-occurrence" of WT and SCC. Of the 237 studies identified, 12 comprising 18 patients met the inclusion criteria, to which we added one study from our institution.

Tailored Hydration With Lactated Ringer's Solution for Postendoscopic Retrograde Cholangiopancreatography Pancreatitis Prevention: A Randomized Controlled Trial.

Introduction: Aggressive hydration using lactated Ringer's solution prevents postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). Concerns of this strategy are large volume and lengthy hydration. Our study aimed to evaluate the efficacy of tailored aggressive hydration (TAH) for PEP prevention.

Endoscopic ultrasound-guided tissue sampling induced pancreatic duct leak resolved by the placement of a pancreatic stent: A case report.

Background: Pancreatic ductal leaks complicated by endoscopic ultrasonography-guided tissue sampling (EUS-TS) can manifest as acute pancreatitis.

Case Summary: A 63-year-old man presented with persistent abdominal pain and weight loss. Diagnosis: Laboratory findings revealed elevated carbohydrate antigen 19-9 (5920 U/mL) and carcinoembryonic antigen (23.

Importance of differential diagnosis of EBV mucocutaneous ulcer and EBV-positive diffuse large B-cell lymphoma: A case report.

Rationale: Epstein-Barr virus mucocutaneous ulcers (EBVMCUs) were officially recognized as a clinicopathologic entity in the 2017 revision of the World Health Organization classification, which often occurs in the elderly or in immunosuppressive condition presented as an isolated ulcerative lesion. EBVMCUs are defined as "shallow, sharply circumscribed, mucosal or cutaneous ulcers with underlying polymorphous infiltration." It mostly involves oral mucosa, but some appear in skin or gastrointestinal tract.

Convolutional neural network model for automatic recognition and classification of pancreatic cancer cell based on analysis of lipid droplet on unlabeled sample by 3D optical diffraction tomography.

Introduction: Pancreatic cancer cells generally accumulate large numbers of lipid droplets (LDs), which regulate lipid storage. To promote rapid diagnosis, an automatic pancreatic cancer cell recognition system based on a deep convolutional neural network was proposed in this study using quantitative images of LDs from stain-free cytologic samples by optical diffraction tomography.

Methods: We retrieved 3D refractive index tomograms and reconstructed 37 optical images of one cell.

Management of post-liver transplantation biliary stricture inaccessible by endoscopic retrograde cholangiopancreatography: A case report.

Background: One challenging scenario in the treatment of biliary stricture is that post-liver transplantation (LT) biliary strictures cannot be accessed using endoscopic retrograde cholangiopancreatography (ERCP). Here, we report such a case that was successfully treated using a novel endoscopic technique.

Case Summary: A 60-year-old man presented with obstructive jaundice caused by a post-LT biliary stricture.

Atomistic insights into adhesion characteristics of tungsten on titanium nitride using steered molecular dynamics with machine learning interatomic potential.

As transistor integration accelerates and miniaturization progresses, improving the interfacial adhesion characteristics of complex metal interconnect has become a major issue in ensuring semiconductor device reliability. Therefore, it is becoming increasingly important to interpret the adhesive properties of metal interconnects at the atomic level, predict their adhesive strength and failure mode, and develop computational methods that can be universally applied regardless of interface properties. In this study, we propose a method for theoretically understanding adhesion characteristics through steering molecular dynamics simulations based on machine learning interatomic potentials.