The fusion of LiDAR and camera sensors offers remarkable results in multimodal 3D object detection with enhanced performance. However, existing fusion methods are primarily designed considering ideal data, ignoring the practical challenges of sensor specification and environmental variations encountered in autonomous driving. Thus, these methods often exhibit a significant performance degradation when faced with adverse conditions, such as sparse point cloud and inclement weather.
View Article and Find Full Text PDFBackground: The factors associated with extrahepatic recurrence (EHR) after curative resection for hepatocellular carcinoma (HCC) have rarely been investigated. This study examined the pre- and postoperative predictors of EHR after curative resection in HCC patients over a ten-year follow-up period.
Methods: A retrospective review was conducted on treatment-naïve HCC patients who underwent curative resection between 2004 and 2019 at four tertiary hospitals in South Korea.
Bile acid (BA) metabolism and signaling may influence cancer risk. We investigated differences in circulating BA composition between healthy controls and patients with colorectal cancer (CRC) and assessed the epithelial-mesenchymal transition (EMT) in CRC cell lines exposed to chenodeoxycholic acid (CDCA). BA, C4, and fibroblast growth factor-19 (FGF19) concentrations in serum samples from 70 controls and 133 patients with CRC were analyzed.
View Article and Find Full Text PDFBackground: The advent of direct-acting antivirals (DAAs) has marked a significant milestone in the therapeutic landscape of hepatitis C, greatly improving treatment efficacy. A therapeutic regimen encompassing sofosbuvir (SOF), velpatasvir (VEL), and voxilaprevir (VOX) has demonstrated strong efficacy across all genotypes of the hepatitis C virus (HCV) and has recently been incorporated into the Korean healthcare system. This study aimed to evaluate the real-world efficacy and safety of these antivirals in the South Korean population.
View Article and Find Full Text PDFLimited-angle computed tomography (LACT) offers patient-friendly benefits, such as rapid scanning and reduced radiation exposure. However, the incompleteness of data in LACT often causes notable artifacts, posing challenges for precise medical interpretation. Although numerous approaches have been introduced to reconstruct LACT images into complete computed tomography (CT) scans, they focus on improving image quality and operate separately from lesion segmentation models, often overlooking essential lesion-specific information.
View Article and Find Full Text PDFBackground/aims: Due to the very low incidence of human immunodeficiency virus (HIV) infection in South Korea, epidemiological data on hepatitis C virus (HCV)/HIV coinfection are limited. The aim of this study was to investigate the clinical characteristics and treatment outcomes of patients with HCV/HIV coinfection in South Korea.
Methods: We retrospectively collected data from patients diagnosed with HCV/HIV coinfection at 12 academic hospitals in South Korea from 2009 to 2020.
From the last several decades, previous studies have found that salt can increase the resistance of Gram-negative human-pathogenic bacteria to acidic environments in the presence of weak organic acids (OAAs), significantly increasing or extending the survival of Escherichia coli O157:H7, Salmonella enterica serovar Typhimurium, Shigella sp., and Cronobacter sp., particularly in acidified foods.
View Article and Find Full Text PDFBackground/objectives: Extrahepatic recurrence (EHR) is a significant negative prognostic factor in hepatocellular carcinoma (HCC). Although EHR is commonly observed in high-risk patients following HCC hepatectomy, its occurrence without concurrent intrahepatic HCC remains poorly understood. Therefore, this study aims to examine the clinical characteristics and risk factors associated with EHR in patients without intrahepatic HCC at diagnosis.
View Article and Find Full Text PDFFood Sci Biotechnol
June 2025
This study investigated the survival and growth parameters of serovar Bareilly inoculated in precooked ingredients (burdock, carrot, cheese, egg, ham, radish, and spinach) used in making at a given storage temperature of 25 °C, in order to predict the growth rate (GR) and lag time (LT) using the modified Gompertz equation. As a result, all ingredients gradually promoted the growth of sp., exceeding 10 to 10 CFU/g at 25 °C within 48 h.
View Article and Find Full Text PDFThis study aimed to characterize the ability of the group isolated from conventionally, organically or pesticide-freely grown vegetables to form biofilms with regard to cell surface hydrophobicity (CSH), slime production, and antibiotic susceptibility. Cellular properties (biofilm formation, CSH, and slime production) were measured using an in vitro microplate assay with crystal violet staining, adhesion to hydrocarbons assay, and Congo red broth method, respectively. Consequently, 16, 16, and 16 .
View Article and Find Full Text PDFBackgrounds/aims: Hepatocellular carcinoma (HCC) is the sixth most common cancer and second leading cause of cancer-related deaths in South Korea. This study evaluated the characteristics of Korean patients newly diagnosed with HCC in 2016-2018.
Methods: Data from the Korean Primary Liver Cancer Registry (KPLCR), a representative database of patients newly diagnosed with HCC in South Korea, were analyzed.
This study was to examine the relationship between preexposure to salt and stress-responsive resistance to acid, bile salt, and heat in Cronobacter sakazakii, Salmonella enterica serovar Enteritidis, Bacillus cereus, and Staphylococcus aureus. Stationary phase-grown cultures of C. sakazakii, S.
View Article and Find Full Text PDFRadiofrequency ablation (RFA) is an important local treatment for hepatocellular carcinoma (HCC). This study aimed to evaluate the characteristics of tumor recurrence after RFA and analyze predictors of tumor recurrence and survival in patients with HCC. We retrospectively reviewed data from treatment-naïve patients with HCC who underwent RFA for HCC treatment between 2008 and 2017 at four tertiary hospitals in South Korea.
View Article and Find Full Text PDFThe interactive pathway of the gut-liver axis underscores the significance of microbiome modulation in the pathogenesis and progression of various liver diseases, including hepatocellular carcinoma (HCC). This study aims to investigate the disparities in the composition and functionality of the hepatic microbiota between tumor tissues and adjacent normal liver tissues, and their implications in the etiology of HCC. We conducted a comparative analysis of the hepatic microbiome between adjacent normal liver tissues and tumor tissues from HCC patients.
View Article and Find Full Text PDFThe study aimed to evaluate the synergistic interaction of organic acids (OAAs) or lemon extract (LE) plus mild heat (MH; 55 °C) against O157:H7, serovar Typhimurium, and inoculated in beetroot and watermelon juices. A mixed culture cocktail of . O157:H7, .
View Article and Find Full Text PDFFood processing industries commonly employ organic acids (OAAs) to determine bacterial contamination in acidified and fermented foods. OAAs are believed to possess potent antimicrobial properties by permeating cell membranes, altering proton and anion concentrations in the cytoplasm due to their lipophilic undissociated forms. The bacteriostatic or bactericidal effects of OAAs are influenced by various factors including microbial physiology, environmental pH, and acid dissociation ratios.
View Article and Find Full Text PDFIntroduction: Aggressive hydration using lactated Ringer's solution prevents postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). Concerns of this strategy are large volume and lengthy hydration. Our study aimed to evaluate the efficacy of tailored aggressive hydration (TAH) for PEP prevention.
View Article and Find Full Text PDFCancer Genomics Proteomics
April 2024
Background/aim: Transcriptional factor prospero homeobox-1 (PROX-1) is crucial for the embryonic development of various organs and cell fate specification. It exhibits either an oncogenic or tumor suppressive activity depending on cancer types. However, the relationship between PROX-1 and hepatocellular carcinoma (HCC) remains obscure.
View Article and Find Full Text PDFFood Sci Biotechnol
January 2024
Unlabelled: This study analyzed the virulence, growth characteristics, and cytotoxicity of strains isolated from fresh produce, including romaine lettuce, sesame leaf, tomato, and cucumber grown by different methods. Polymerase chain reaction (PCR) was used to assess the toxigenic potential, and the cytotoxicity of was estimated using cell-free supernatant in HEp-2 cells. The study found that was the predominant diarrheal enterotoxin in the 59 isolated strains, followed by and .
View Article and Find Full Text PDFThis study aims to investigate the resistance of E. coli O157:H7 to acetic acid (AA) or malic acid (MA) by adding osmolytes, such as glycerol, glycine, glucose, and fructose, in Luria-Bertani broth without NaCl (LB) or phosphate buffer (PB) stored at 25 °C. In LB, a significantly (p < 0.
View Article and Find Full Text PDFJ Liver Cancer
September 2023
Although hepatocellular carcinoma (HCC) is associated with a poor prognosis, management of early-stage HCC is often successful with highly efficacious treatment modalities such as liver transplantation, surgical resection, and radiofrequency ablation. However, unfavorable clinical outcomes have been observed under certain circumstances, even after efficient treatment. Factors that predict unsuitable results after treatment include tumor markers, inflammatory markers, imaging findings reflecting tumor biology, specific outcome indicators for each treatment modality, liver functional reserve, and the technical feasibility of the treatment modalities.
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