Robot-assisted vs. open radical cystectomy: octogenarians vs. non octogenarians.

Introduction: We quantified the effect of robot-assisted radical cystectomy (RARC) vs. open radical cystectomy (ORC) on adverse in-hospital outcomes in octogenarians (≥80 years) relative to non-octogenarians.

Material And Methods: Propensity score matching (PSM), multivariable logistic and Poisson regression models focused on adverse in-hospital outcomes in octogenarian and non-octogenarian patients treated with RARC vs.

An unusual renal colic during trans-arterial embolization after trauma and its multidisciplinary management.

Selective embolization is the treatment of choice for traumatic renal pseudoaneurysm (PSA) in stable patients. N-Butyl-2-cyanoacrilate (NBCA) is an embolic agent frequently used to embolize peripheral lesions. N-Butyl-2-cyanoacrilate is one of the most widely used embolic materials because it is easy to prepare, it acts quickly and is highly cost-effective.

Oxidative Stress and Semen Quality Among Night- and Day-Shift Workers: A Cross-Sectional Study.

Infertility affects 15% of couples, with oxidative stress recognized as a key contributor to male infertility. Night-shift work, through circadian disruption, may exacerbate oxidative imbalance and impair reproductive function. This study investigates the impact of night-shift work on oxidative stress and semen quality and evaluates the potential benefits of antioxidant supplementation in this context.

Serum total testosterone and testicular histology help predicting positive sperm retrieval in nonmosaic Klinefelter patients undergoing testicular sperm extraction: real-life data from a large multicenter cohort.

Objective: To study real-life rates and predictors of sperm retrieval (SR) in men with nonmosaic Klinefelter syndrome (KS) seeking medical help for primary male factor couples' infertility.

Design: Multicenter, retrospective, cohort study.

Subjects: Data analysis from 383 non-Finnish, White-European, nonmosaic KS men with nonobstructive azoospermia (NOA) undergoing testicular sperm extraction (TESE) between 2008 and 2024 at 12 tertiary referral centers in Italy.

Vacuum-assisted mini-percutaneous nephrolithotomy is associated with lower rates of infectious complications compared to standard procedures in low-risk patients: a single-center experience.

Purpose: To evaluate the impact of vacuum-assisted mini-percutaneous nephrolithotomy (vamPCNL) vs. vacuum-cleaner mPCNL (vcmPCNL) on the rate of postoperative infectious complications in a cohort of patients with low risk factors for infections.

Methods: We retrospectively analysed data from 229 patients who underwent mPCNL between 01/2016 and 09/2024.

Enhanced prognostic value of four-tier hybrid grading system in Ta non-muscle-invasive bladder cancer.

Objectives: To compare the predictive performance of the World Health Organization (WHO) 1973, WHO 2004/2022, the three-tier (low grade [LG]/Grade 1 [G1]-G2, high grade [HG]/G2, and HG/G3), and four-tier (LG/G1, LG/G2, HG/G2, and HG/G3) hybrid grading systems in Ta non-muscle-invasive bladder cancer (NMIBC), by evaluating recurrence-free survival (RFS) and progression-free survival (PFS).

Patients And Methods: This retrospective multicentre study included 1233 patients with pTa NMIBC treated with transurethral resection of bladder tumour, eventually followed by intravesical instillations as determined by their physicians, between 2010 and 2023, across 18 Italian hospitals. Pathologists graded resected tissues using the WHO 1973, WHO 2004/2022 classifications, and hybrid three-tier (LG, HG/G2, HG/G3) and four-tier (LG/G1, LG/G2, HG/G2, HG/G3) systems.

Decision Regret About Testicular Prosthesis After Radical Orchiectomy: Real-life Data to Improve Preoperative Patient Counseling.

Background And Objective: Patients undergoing orchiectomy for testicular cancer (TC) may have body image concerns, with a testicular prosthesis (TP) as a potential solution. Data on regret regarding synchronous TP placement are limited. We investigated postoperative patient-reported satisfaction and decision regret after unilateral orchiectomy for TC with or without synchronous TP placement.

Minimally invasive surgical techniques (MISTs) for benign prostatic hyperplasia: results from a Delphi consensus project to shed light on controversial topics.

Purpose: To conduct a Delphi consensus in order to address key uncertainties and provide expert insights to bridge the gap between guidelines and real-world practice concerning minimally invasive surgical techniques (MISTs) for benign prostatic hyperplasia (BPH).

Methods: The Advisory Board developed 343 statements on 35 debated topics in the surgical management of BPH, each including multiple items rated on a 9-point Likert scale. The questionnaire was emailed to a Panel of 28 Italian urologists with 5-year experience in MISTs for the first round of voting.

Residual fragments after percutaneous nephrolithotomy: is it mandatory to treat them all?

To investigate complication rates, stone growth and passage according to residual fragments (RFs) size in a cohort of patients treated with miniPCNL (mPCNL). We retrospectively analysed data from 572 patients who underwent mPCNL between 01/2018 and 11/2023. We identified 105 (19.

Clinical evaluation of the role of miRNA 371 in small testicular masses. Results of the "S1STeM 371" Trial.

Aim Of The Study: Incidental small testicular masses (STMs) pose the dilemma of invasive Vs surveillance. To test miRNA 371 kit (M371, CE approved) in predicting germ cells tumor (GCT) in patients with STM.

Methods: Thirty-two consecutive men with a STM between 5 and 20 mm have been prospectively accrued.

Organ preservation and oncological efficacy of peniscopically controlled CO laser excision of penile squamous cell carcinoma: Early and late results in a high-volume center.

Objectives: To evaluate safety and early and long-term efficacy of CO laser conservative treatments for nonulcerative squamous cell carcinoma (SCC) of the penis.

Material And Methods: Within our institutional database (2002-2022, included), we identified 122 consecutive cT1-2 cN0 cM0 patients with penile SCC who underwent conservative CO laser treatments. Histologically confirmed local relapses were recorded.

Semi-closed-circuit vacuum-assisted mini percutaneous cystolithotomy (VAMPCL) in native and augmented bladders.

Bladder stones in children are rare, 1-5 % of all urinary tract stones. Historically, open cystolithotomy (OCL) was the standard treatment. New methods such as extracorporeal shock wave cystolithotripsy (ESWCL), percutaneous cystolithotomy (PCL), and transurethral cystolithotripsy (TCL) have been introduced to reduce complications and shorten hospital stays.

Effectiveness and patient satisfaction with the new sildenafil oral suspension formulation compared to sildenafil oro-dispersible film: a real-life study.

Sildenafil is one of the most used phosphodiesterase type 5 inhibitor (PDE5i) for the treatment of erectile dysfunction (ED) in clinical practice. A new oral suspension formulation (OSF) of sildenafil has been introduced to overcome the drawbacks of previous formulations. We assess the efficacy and patients' experience with sildenafil 50 mg OSF in men with ED who were taking the sildenafil oro-dispersible film (ODF).

Semi-closed-circuit vacuum-assisted mini percutaneous cystolithotomy (vamPCL) in the pediatric population: Initial experience of a novel technique in native and augmented bladders.

Introduction: Bladder stones (BS) in children are a rare condition and represent 1-5 % of all urinary tract stones. With advances in miniaturized endoscopes and intracorporeal lithotripters, percutaneous cystolithotomy has been demonstrated to be an effective, safe and quick technique, despite the longer operative time. This limitation may be overcome by a semi-closed-circuit vacuum-assisted technology (vamPCL), characterized by a continuous inflow and a suction-controlled outflow (ClearPetra®).

A Trifecta-Based Evaluation of Patients Treated with Percutaneous Thermal Ablation of Small Renal Masses.

Scoring metrics are important to compare outcomes of different percutaneous treatments for small renal masses (RMs). The concept of trifecta (no complications, kidney function preservation, and absence of local recurrence) has been recently introduced in percutaneous thermal ablation of RM. In this context, previous studies have shown that cryoablation (CA) and microwave ablation (MWA) have similar outcomes.

Clinical significance of stone culture during endourological procedures in predicting post-operative urinary sepsis: should it be a standard of care-evidence from a systematic review and meta-analysis from EAU section of Urolithiasis (EULIS).

Purpose: Urinary sepsis is the leading cause of mortality in the setting of endourological procedures for stone treatment such as URS and PCNL; renal stones themselves may be a source of infection. Aim of this study is to determine the diagnostic accuracy of stone cultures (SC) collected during URS and PCNL in predicting post-operative septic complications, compared to preoperative bladder urine culture (BUC).

Methods: We performed a systematic review (SR) of literature according to the PRISMA guidelines; Literature quality was evaluated according to The Risk Of Bias In Non-randomized Studies-of Interventions (ROBINS-I) assessment tool.

Radiotherapy Versus Partial Penectomy for T1 Squamous Cell Carcinoma of the Penis.

Background: Radiotherapy (RT) represents an alternative treatment option for patients with T1 squamous cell carcinoma of the penis (SCCP), with proven feasibility and tolerability. However, it has never been directly compared with partial penectomy (PP) using cancer-specific mortality (CSM) as an end point.

Methods: In the Surveillance, Epidemiology, and End Results database (2000-2020), T1N0M0 SCCP patients treated with RT or PP were identified.

The relationship between the force applied and perceived by the surgeon during ureteral access sheath placement: ex-vivo experimental model.

Purpose: To define a peak force of insertion (PFOI) threshold for ureteral damage during ureteral access sheath (UAS) placement on an experimental ureteral orifice model.

Methods: A specially designed water tank using 2 laparoscopic 5 mm ports and 2 different size (10 Fr and 8 Fr) sealing cap adaptors (SCA) as ureteral orifices was used to perform the test. A 10-12 Fr UAS was fixed to a load cell and the force of insertion (FOI) was continuously recorded with a digital force gauge.