Cancer-specific mortality in secondary bladder cancer after nephroureterectomy for upper tract urothelial carcinoma.

Objective: To examine differences in cancer-specific mortality (CSM) in nonmetastatic upper tract urothelial carcinoma (UTUC) patients with vs. without secondary bladder cancer (BCa) after radical nephroureterectomy (RNU).

Methods: Within the Surveillance, Epidemiology, and End Results database (SEER 2000-2021), T1-T4N0M0 UTUC patients treated with RNU and diagnosed with secondary BCa were identified.

Upper urinary tract urothelial carcinoma diagnosis effect on life expectancy relative to population-based controls: a retrospective analysis.

Purpose: To exam five-year overall survival (OS) of upper urinary tract urothelial carcinoma (UTUC) patients versus age- and sex-matched population-based controls.

Methods: Within Surveillance, Epidemiology, and End Results database (2004-2020), we identified newly diagnosed (2004-2015) UTUC patients. Relying on Social Security Administration Life Tables (2004-2020) age- and sex- matched population-based controls were simulated (Monte Carlo simulation).

Intravesical recurrence after therapeutic ureteroscopy for upper tract urothelial carcinoma: a meta-analysis.

Objective: To assess the role of ureteroscopy (URS) with laser ablation on oncological outcomes, namely, intravesical recurrence (IVR) rate, radical nephroureterectomy (RNU)-to-treat ratio and overall survival (OS), in patients with upper tract urothelial carcinoma (UTUC), an area of study that has been insufficiently addressed in the literature.

Materials And Methods: A systematic search (PROSPERO: CRD42025642480) was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement. A pooled analysis was performed to quantify the effect size (ES) for IVR rate, radical nephroureterectomy (RNU)-to-treat ratio and OS.

Strategies for preventing port-site hernia following robot-assisted radical prostatectomy: a systematic review.

Background: Trocar site hernia is a recognized but often underreported complication of minimally invasive surgery, including robotic-assisted radical prostatectomy. While relatively rare, trocar site hernia can lead to severe complications such as bowel obstruction, strangulation, and the need for emergency surgical intervention. Trocar size has been identified as a primary risk factor, with hernias occurring predominantly at sites where 10 mm or larger trocars are used.

Contemporary rates and predictors of prolonged hospital stay after radical cystectomy: a population-based analysis.

Objective: To test contemporary rates and predictors of prolonged hospital stay after radical cystectomy (RC) and ileal conduit in non-metastatic bladder cancer patients.

Methods: Within the National Inpatient Sample database (NIS, 2008-2019), we identified ileal conduit RC patients and tabulated length of stay (LOS) ≥ 75th percentile vs. others.

Perioperative Complications and In-Hospital Mortality After Radical Prostatectomy in Prostate Cancer Patients with a History of Heart Valve Replacement.

To test for in-hospital mortality and complication rates in a population-based group of patients with vs. without a history of heart valve replacement undergoing radical prostatectomy (RP). Relying on the National Inpatient Sample (2000-2019), prostate cancer patients undergoing RP were stratified according to the presence or absence of heart-valve replacement.

Temporal Trends and Differences in Inpatient Palliative Care Use in Metastatic Penile Cancer Patients.

: To quantify inpatient palliative care use over time and to test whether patient or hospital characteristics represent determinants of inpatient palliative care use in patients with metastatic penile cancer. : Relying on the National Inpatient Sample database (2006-2019), we identified 1017 metastatic penile cancer patients. Estimated annual percentage change analyses and multivariable logistic regression models addressing inpatient palliative care use were fitted.

Does Race/Ethnicity Affect Secondary Bladder and Rectal Cancer Rates After Prostate Cancer Radiation? Results from a Population-Based Study.

Background: It is unknown whether race/ethnicity affects the risk of secondary bladder cancer (BCa) or rectal cancer (RCa) after external beam radiation therapy (EBRT) or brachytherapy (BT) for prostate cancer (PCa).

Materials And Methods: Within the Surveillance, Epidemiology, and End Results database (2004-2020), we focused on Caucasians, Hispanics, African Americans (AAs), and Asian/Pacific Islanders (APIs). Cumulative incidence plots and competing risks regression (CRR) models were fitted.

Proctoring in robot-assisted urologic surgery: insights from a multicenter survey.

The implementation of robot-assisted laparoscopic surgery (RALS) requires structured educational models to ensure safety, efficacy, and procedural standardization. Among these, proctoring, where experienced robotic surgeons support peers during their early procedures, plays a pivotal role. However, specific evidence in the current literature remains limited.

The effect of race/ethnicity on systemic chemotherapy in urothelial carcinoma patients exposed to radiotherapy.

Introduction: Based on prospective trials' result, it is unknown whether race/ethnicity affects the magnitude of cancer-specific survival differences after trimodal therapy (TMT) versus external beam radiation therapy alone (EBRT) for urothelial carcinoma for urinary bladder (UCUB). We addressed this knowledge gap.

Materials And Methods: Within the Surveillance, Epidemiology, and End Results database (2004-2020), we identified patients with cT2-T4aN0M0 UCUB treated with either TMT or EBRT.

Perioperative outcomes in testicular cancer patients treated with retroperitoneal lymph node dissection.

Objective: No large-scale population-based studies quantified perioperative outcomes in testicular cancer (TC) patients treated with retroperitoneal lymph node dissection (RPLND), especially in non-metastatic and metastatic stages. Moreover, no previous studies compared outcomes in centers of excellence (Indiana University School of Medicine, Memorial Sloan Kettering Cancer Center, and MD Anderson Cancer Center) vs. large-scale population-based databases.

Outcomes and safety of trans perineal laser ablation of the prostate: a systematic review.

Objective: Prostate trans-perineal laser ablation (TPLA) is a minimally invasive treatment for benign prostatic hyperplasia (BPH) that is gaining importance as an alternative to the standard of care, namely transurethral resection of the prostate (TURP). To evaluate the functional outcomes and rates of complication in BPH patients with LUTS who underwent TPLA.

Materials And Methods: We performed a scoping systematic review (PROSPERO id CRD42024612152) on PubMed/Medline, Embase, and the Cochrane Library in June 2025 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) statement.

Prostate Cancer Outcomes in Immunocompromised Patients: A Systematic Review and Meta-analysis.

Background And Objective: The role of immunosuppression in prostate cancer (PCa) mortality is a debated topic, with a low level of evidence. This review aims to evaluate the cancer-specific mortality (CSM) and overall mortality (OM) of PCa in immunocompromised patients compared with immunocompetent individuals.

Methods: A literature search was conducted in the PubMed/Medline, Embase, and Web of Science databases (up to the March 31, 2024).

Effect of sex on adverse in-hospital outcomes after radical cystectomy according to urinary diversion type.

Objective: To test for differences in adverse in-hospital outcomes between females vs. males after radical cystectomy (RC) according to specific urinary diversion type (neobladder vs. ileal conduit).

Perioperative Complications and In-hospital Mortality After Cystectomy for Nonbladder Cancer Conditions Versus Radical Cystectomy for Bladder Cancer.

Objective: This study was designed to test for perioperative complications, mortality, and length of stay after cystectomy for nonbladder cancer (non-BCa) v radical cystectomy (RC) for bladder cancer (BCa).

Methods: Patients were identified within the National Inpatient Sample (2000-2019). Multivariable logistic and Poisson regression models were fitted.

Costs of robot-assisted vs. open approaches for 5 major cancers.

To test for differences in total hospital cost (THC) between robot-assisted vs. open major cancer surgeries, colectomy, esophagectomy, radical hysterectomy, lung resection and pancreatectomy. Within the National Inpatient Sample (2016-2019), we identified all robot-assisted vs.

Effect of chemotherapy on cancer specific mortality in female locally advanced urethral cancer.

Objective: To quantify the effect of chemotherapy (CHT) in locally advanced female primary urethral cancer (fPUC).

Methods: In the Surveillance, Epidemiology and Ends Results (SEER) database (2000-2021), we identified 295 fPUC patients with locally advanced stage treated with local therapy (surgery or radiation or both) with or without CHT. Multivariable Cox regression models addressed cancer specific mortality free survival (CSM).

Comparison of In-Hospital Outcomes at Robot-Assisted Versus Open Partial Nephrectomy.

Objective: The aim of this work is to quantify the magnitude of improvement in in-hospital outcomes between historical and contemporary robot-assisted partial nephrectomy (RPN) versus historical and contemporary open PN (OPN).

Methods: Within the Nationwide Inpatient Sample (2010-2019), we identified patients who underwent RPN and OPN. Multivariable logistic regression models were fit.

Total hospital cost of robot-assisted approach in major urological cancer surgeries.

Background: The aim of this study was to test for differences in total hospital cost (THC) between robot-assisted vs. open partial nephrectomy (PN), radical cystectomy (RC), radical prostatectomy (RP) and radical nephroureterectomy (NU).

Methods: Within the National Inpatient Sample (2010-2019), we identified all robot-assisted vs.

A systematic review assessing the reliability of studies focusing on urological content on YouTube.

Introduction: In recent years, several publications have focused on analyzing the quality of medical content on YouTube. The current systematic review aimed to summarize and analyze the available studies examining YouTube video content in the urological field.

Evidence Acquisition: This is a systematic review including studies examining urological content uploaded on the YouTube platform published before November 2023.

Local Tumor Destruction Versus Partial Penectomy for T1a Squamous Cell Carcinoma of the Penis.

Background: Local tumor destruction (LTD) represents a relatively novel approach for the management of early-stage squamous cell carcinoma of the penis (SCCP). Its cancer control efficacy has never been tested in large-scale epidemiologic studies. We addressed this knowledge gap and tested for differences in cancer-specific mortality (CSM) between LTD versus partial penectomy (PP) in T1aN0M0 SCCP.

Endoscopic ablation versus nephroureterectomy in localized low-grade upper tract urothelial carcinoma: a comparison in terms of cancer-specific and other-cause mortality.

Purpose: Guidelines recommend endoscopic ablation in select upper urinary tract urothelial carcinoma (UTUC) patients. To test for differences in cancer-specific mortality (CSM) and other-cause mortality (OCM) in localized non-invasive low-grade UTUC with tumor size < 2 cm treated with endoscopic ablation vs. radical nephroureterectomy.

Adverse In-Hospital Outcomes Following Robot-Assisted vs. Open Radical Prostatectomy in Quadragenarians.

: Adverse in-hospital outcomes at radical prostatectomy have not been specifically addressed in young patients aged 40-49 years (quadragenarians). Additionally, no comparison between robot-assisted (RARP) vs. open radical prostatectomy (ORP) has been reported in this population.