Evaluating the metal pollution status and ecological risks in wetland sediments, as well as identifying the sources, is essential for safeguarding the ecological functionality and sustainable development of wetlands. This study examined a coastal wetland park, converted from a dike fishery and farmland, to assess potential metal pollution. Within the park, 26 surface sediment samples were collected, and the concentrations of metals (Li, Be, V, Cr, Co, Cu, Zn, Cd, Pb, As, and Mn) were analyzed.
View Article and Find Full Text PDFObjectives: Alzheimer's disease (AD) is a prevalent neurodegenerative disorder, characterized by progressive cognitive decline. Current approved drugs merely relieve symptoms rather than halt or reverse disease progression. The role of the brain lymphatic system in clearing harmful substances in the brain has provided new insights for AD treatment.
View Article and Find Full Text PDFZhonghua Nan Ke Xue
August 2023
Objective: To observe the effect of Nailifu Spray on the treatment of premature ejaculation.
Methods: A total of 90 patients were included in this study from January 1, 2022 to January 1, 2023. Nailifu spray was used to spray the surface of penile skin once a day, 2 sprays per session for 4 weeks.
Purpose: Aim to create and validate a comprehensive nomogram capable of accurately predicting the transition from moderate-severe to normal-mild xerostomia post-radiotherapy (postRT) in patients with nasopharyngeal carcinoma (NPC).
Materials And Methods: We constructed and internally verified a prediction model using a primary cohort comprising 223 patients who were pathologically diagnosed with NPC from February 2016 to December 2019. LASSO regression model was used to identify the clinical factors and relevant variables (the pre-radiotherapy (XQ-preRT) and immediate post-radiotherapy (XQ-postRT) xerostomia questionnaire scores, as well as the mean dose (D) delivered to the parotid gland (PG), submandibular gland (SMG), sublingual gland (SLG), tubarial gland (TG), and oral cavity).
Purpose: The aim of this study was to identify the efficacy of diffusion kurtosis imaging (DKI) in tracking and monitoring the dynamic change of parotid glands (PGs), submandibular glands (SMGs), sublingual glands (SLGs), and acute xerostomia in nasopharyngeal carcinoma (NPC) patients treated with induction chemotherapy (IC) plus concurrent chemoradiotherapy (CCRT).
Methods: The prospective study recruited 42 participants treated with IC+CCRT. All patients underwent DKI scanning six times: before IC, before RT, in the middle of the RT course, immediately after RT, and 1 and 3 months post-RT.
Brain lesions can cause neural stem cells to activate, proliferate, differentiate, and migrate to the injured area. However, after traumatic brain injury, brain tissue defects and microenvironment changes greatly affect the survival and growth of neural stem cells; the resulting reduction in the number of neural stem cells impedes effective repair of the injured area. Melatonin can promote the survival, proliferation, and differentiation of neural stem cells under adverse conditions such as oxidative stress or hypoxia that can occur after traumatic brain injury.
View Article and Find Full Text PDFHypoalbuminemia is associated with poor outcome in patients undergoing surgery intervention. The main aim for this study was to investigate the incidence and the risk factors of postoperative hypoalbuminemia and assessed the impact of postoperative hypoalbuminemia on complications in patients undergoing brain tumor surgery. This retrospective study included 372 consecutive patients who underwent brain tumors surgery from January 2017 to December 2019.
View Article and Find Full Text PDFBackground: Functional MRI (fMRI) parameters analysis has been proven to be a promising tool of predicting therapeutic response to induction chemotherapy (IC) in nasopharyngeal carcinoma (NPC). The study was designed to identify and compare the value of fMRI parameters in predicting early response to IC in patients with NPC.
Methods: This prospective study enrolled fifty-six consecutively NPC patients treated with IC from January 2021 to May 2021.
Radiother Oncol
April 2021
Purpose: To verify clinical significance of submandibular gland (SMG)-sparing during helical tomotherapy (HT) for nasopharyngeal carcinoma (NPC) from the perspective of imaging by using diffusion weighted imaging (DWI).
Materials And Methods: In this prospective study, 60 NPC patients scheduled for radical SMG-sparing HT were enrolled. All patients underwent DWI examinations prior to HT (pre-HT) and 1, 3, 6, 9, 12 months post HT.
Incorporating plasmonic nanostructures is a promising strategy to enhance both the optical and electrical characteristics of photovoltaic devices via more efficient harvesting of incident light. Herein, we report a facile fabrication scheme at low temperature for producing gold nanoparticles embedded in anatase TiO films, which can simultaneously improve the efficiency and stability of n-i-p planar heterojunction perovskite solar cells (PSCs). The PSCs based on rigid and flexible substrates with 0.
View Article and Find Full Text PDFWorld J Surg Oncol
August 2020
Background: Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver, and its morbidity and mortality have been increasing in recent years. The early diagnosis and prompt treatment of small HCC are crucial to improve the prognosis and quality of life of patients. In China, hepatitis B virus infection is the main cause.
View Article and Find Full Text PDFBackground: Pathological manifestations of hepatic tumours are often associated with prognosis. Although surgical specimens (SS) can provide more information, currently, pre-treatment needle core biopsy (NCB) is increasingly showing important value in understanding the nature of liver tumors and even in diagnosis and treatment decisions. However, the concordance of the clinicopathological characteristics and immunohistochemical (IHC) staining between NCB and SS from patients with hepatic tumours were less concerned.
View Article and Find Full Text PDFCamptothecin (CPT) is a cytotoxic quinoline alkaloid that is used clinically as an anticancer drug. However, the clinical application of CPT is limited due to its low solubility as well as serious and unfathomable side-effects. In the present study, we created a novel 10-hydroxy CPT prodrug, ZBH-ZM‑06.
View Article and Find Full Text PDFObjective This study was performed to identify the correlation between contrast-enhanced ultrasound (CEUS) and contrast-enhanced multidetector computed tomography (CE-MDCT) as well as the correlation between serum liver enzyme concentrations and CE-MDCT in classification of the severity of blunt hepatic trauma using CE-MDCT as a reference standard. Materials and methods A blunt liver trauma model was created using 20 rabbits, and CE-MDCT, CEUS, and serum liver enzyme assays were performed. A radiologist and an ultrasound physician independently evaluated the degree of liver trauma.
View Article and Find Full Text PDFUncontrolled hemorrhage after trauma to the liver can lead to death. The present study compared the effects of non-focused microbubble-enhanced ultrasound and high-intensity focused ultrasound on hepatic hemostasis in the injured liver. Blood perfusion level, serum liver enzyme levels and the aspartate transaminase/alanine transaminase ratio differed between the two types of treatment (all p values < 0.
View Article and Find Full Text PDFExp Biol Med (Maywood)
January 2017
The aim of our study was to investigate the hemostatic mechanism underlying microbubble-enhanced non-focused ultrasound treatment of liver trauma. Thirty rabbits with liver trauma were randomly divided into three groups-the microbubble-enhanced ultrasound (MEUS; further subdivided based on exposure intensity into MEUS1 [0.11 W/cm], MEUS2 [0.
View Article and Find Full Text PDFObjectives. The aim of this study was to detect factors associated with small bowel obstruction (SBO) caused by bezoars on multidetector computed tomographic findings. Methods.
View Article and Find Full Text PDFFrom transportation networks to complex infrastructures, and to social and economic networks, a large variety of systems can be described in terms of multiplex networks formed by a set of nodes interacting through different network layers. Network robustness, as one of the most successful application areas of complex networks, has attracted great interest in a myriad of research realms. In this regard, how multiplex networks respond to potential attack is still an open issue.
View Article and Find Full Text PDFPurpose: Manganese-enhanced MRI (MEMRI) has been applied to a wide range of biological and disease research. The purpose of the study was to use MEMRI to diagnose the acute mesenteric ischemia (AMI).
Methods: The institutional experimental animal ethics committee approved this study.
Manganese-enhanced MRI studies have proven to be useful in monitoring physiological activities associated with calcium ions (Ca(2+)) due to the paramagnetic property of the manganese ion (Mn(2+)), which makes it an excellent probe of Ca(2+) . In this study, we developed a method in which a Mn(2+)-enhanced T1 -map MRI could enable the monitoring of Ca(2+) influx during the early stages of intestinal ischemia-reperfusion (I/R) injury. The Mn(2+) infusion protocol was optimized by obtaining dose-dependent and time-course wash-out curves using a Mn(2+)-enhanced T1-map MRI of rabbit abdomens following an intravenous infusion of 50 mmol/l MnCl2 (5-10 nmol/g body weight (BW)).
View Article and Find Full Text PDFThe aim of the present study was to explore serum microRNA-155 (miR-155) expression in patients with colorectal cancer (CRC) and examined the potential usefulness of this molecule as a biomarker for diagnosis and prognosis in CRC. Serum samples were obtained between May 2007 and March 2013 from 146 CRC patients and 60 healthy controls. Serum miR-155 expression levels were measured by quantitative real time reverse transcription-polymerase chain reaction (qRT-PCR).
View Article and Find Full Text PDFAlthough the total emission of sulphure dioxide (SO2) was reduced by more than 10% in the Eleventh Five-Year-Plan (2006-2010) in China, the total emission of nitrogen oxides (NOx) in the same period kept increasing. In order to evaluate the effects of the emission changes on acid depostion, a ten-year monitoring on forest throughfall was carried out from 2001 to 2010 at Tieshanping, Chongqing in Southwestern China. The results indicated there was a significantly decreasing trend of sulphur deposition and an increasing trend of nitrogen deposition, which coincided well with the dicreasing trend of SO2 emission and increasing tread of NOx emission in Chongqing, respectively.
View Article and Find Full Text PDFActa Crystallogr Sect E Struct Rep Online
July 2009
In the title compound, [Cd(C(8)H(4)O(4))(C(12)H(9)N(3))](n), each Cd(II) ion is six-coordinated in a distorted octa-hedral geometry by four carboxyl-ate O atoms from two benzene-1,4-dicarboxyl-ate anions (L), and two N atoms from one 2-(2-pyrid-yl)benzimidazole ligand. The neighboring Cd(II) ions are bridged by the L ligands, forming a zigzag polymeric chain structure. The chains are further extended into a three-dimensional supra-molecular structure through inter-molecular N-H⋯O hydrogen bonds.
View Article and Find Full Text PDFHuan Jing Ke Xue
February 2008
The potential effects of acidification and liming on the dynamics of carbon pool in forest soil were studied through field experiments at Tieshanping, Chongqing in Southwest China. The changes of dissolved organic matter (DOM) concentration in soil water in different layers within three years after application of limestone or magnesite indicated that soil remediation had leaded to significant decrease of DOM in soil water from mineral layers [e.g.
View Article and Find Full Text PDF