Publications by authors named "Chun-Yan Wei"

Quantum secret sharing is a basic quantum cryptographic primitive, which plays an important role in robust key management and secure multiparty computation etc. In this work, we give a cryptanalysis of efficient controlled semi-quantum secret sharing protocol with entangled states proposed recently, which shows that the controller can recover the secret if he cooperates with any one participant. Furthermore, an external opponent can make participants recover a false secret without being detected by a special denial-of-service attack.

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In Brief: Endometriosis (EM) is a chronic inflammatory disease with unclear pathogenesis, in which peritoneal macrophages play a pivotal role. This study demonstrates that creatine (CR) induces M2 polarization of peritoneal macrophages, promoting angiogenesis, fibrogenesis and lesion progression in EM, offering new insight into potential therapeutic strategies.

Abstract: EM is a chronic inflammatory disease characterized by the growth of endometrium-like tissues outside the uterine cavity, with an unclear pathogenesis.

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Eleven polyketide derivatives, including two new compounds, xanthoradone D () and arisochromophilone (), were isolated from HJ-7, a Chinese medicinal plant Hance-associated fungus. Their structures were elucidated on the basis of spectroscopic analysis and ECD (Electronic Circular Dichroism) calculations. The antibacterial and antifungal activities of the compounds were evaluated.

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The human malaria parasite Plasmodium falciparum (P. falciparum) continues to pose a significant public health challenge, leading to millions of fatalities globally. Halofuginone (HF) has shown a significant anti-P.

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Endometriosis is an estrogen-dependent, progesterone-resistant gynecological disease with an unknown pathogenesis. Compared to women without endometriosis, women with endometriosis have a remarkably high heme level in the peritoneal fluid. To further investigate the pathomechanisms of heme in endometriosis, we aimed to identify the dysregulated expression of heme-trafficking proteins, such as PGRMC1/2 that are also receptors that mediate the non-genomic responses to progesterone, and heme-degrading enzymes between ectopic endometrial stromal cells and their normal counterparts.

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Quantum key distribution (QKD) and quantum key agreement (QKA) are two main branches of key establishment in quantum cryptography. However, the research of QKA falls far behind that of QKD, especially in practicability. The main reason is that QKA needs to resist not only the outside eavesdropping but also the participant cheating.

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Article Synopsis
  • Efferocytosis, the process where macrophages clear apoptotic cells during embryo implantation, is linked to the immune behavior of decidual macrophages (dMΦs) and can affect pregnancy outcomes.
  • The study discovered that in patients with recurrent pregnancy loss (RPL), there was a disruption in the IL-33/ST2 signaling pathway, leading to increased apoptotic cells and altered metabolism in dMΦs, which contributed to the polarization toward a more inflammatory M1 phenotype.
  • Furthermore, the positive feedback loop involving IL-33/ST2 and AXL in efferocytosis may drive pregnancy failure, as demonstrated in both human samples and experiments with IL-33 knockout mice, highlighting the importance of immunometabolism
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Problem: Decidual macrophages (dM ) play an important role in the formation of maternal-fetal immune tolerance. However, factors that influence the immune status of dM and the related potential mechanisms have not been elucidated to date.

Method Of Study: The gene transcription in dM , decidual stromal cells (DSCs), extravillous trophoblasts (EVTs), and peripheral monocytes (pMo) from human samples were measured using real-time polymerase chain reaction (PCR).

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  • Small non-coding RNAs, especially microRNAs (miRNAs) and tRNA-derived small RNAs (tsRNAs), play essential roles in gene regulation in Trichomonas vaginalis, the organism responsible for trichomoniasis, but their characteristics had not been fully understood until now.
  • Using deep sequencing techniques, researchers identified and confirmed the presence of tsRNAs in T. vaginalis, finding that they are more abundant than miRNAs, which were detected at very low levels.
  • This study is the first comprehensive analysis of small RNAs in Trichomonas, revealing three main categories of tsRNAs and insights into their potential function in the organism's biology and disease mechanisms.
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  • * Over three years, 1556 miscarriage specimens were analyzed, discovering chromosomal abnormalities in about 57.52% of cases and identifying 346 CNVs linked to RPL.
  • * Significant duplications in specific chromosome locations were found more frequently in RPL cases, suggesting a genetic basis for RPL, and potential candidate genes and pathways were identified to aid future diagnostics in Chinese women.
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is a rare and endangered shrub species endemic to East Asia. Here, we report the complete chloroplast (cp) genome structure and its taxonomic position within Hydrangeaceae to promote its conservation and restoration. The complete cp genome of was 157,810 bp in length and contained a large single-copy region (LSC) of 86,823 bp and a small single-copy region (SSC) of 18,735 bp, as well as a pair of inverted repeat (IR) regions of 26,126 bp, each.

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Article Synopsis
  • Babesiosis, caused by the parasite Babesia microti, is a growing concern as a tick-borne disease, particularly in urban areas like Beijing, where understanding its prevalence in small mammals is key for assessing human exposure risks.
  • A study conducted in Beijing from 2014 to 2018 trapped 1,391 small mammals, finding a 12.1% infection rate of B. microti, with different genotypes identified, highlighting specific ecological habitats as risk factors.
  • The results signal a widespread presence of B. microti among small mammals and underscore the importance of this information for public health measures aimed at preventing human infections.
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Nitrate esters have been used in clinical practice for more than one century for the treatment of angina. Their clinical effectiveness is due to vasodilator activity in arteries through a method of delivering nitric oxide or a nitric oxide-like compound. Recently, an increasing numbers of functions of this molecule in biology and pathophysiology have been discovered.

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Article Synopsis
  • Endometriosis (EMS) is a chronic condition where tissue similar to the uterine lining grows outside the uterus, causing inflammation and pain.
  • Recent findings show that patients with EMS have higher levels of heme, a byproduct from broken down red blood cells, in their peritoneal fluid compared to those without the condition.
  • This excess heme appears to impair the ability of peritoneal macrophages (a type of immune cell) to clear debris, suggesting a mechanism for the compromised immune response observed in EMS patients.
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Cellulose is the most abundant natural polymer on earth. With the increasing shortage of oil resources, people have been focusing more on producing natural cellulose. In this study, guaiacol was used as the model compound to investigate the degradation of lignin in luffa.

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Efferocytosis, which is known as the phagocytic clearance of dying cells by professional as well as non-professional phagocytes, including a great number of intracellular/extracellular factors and signals, is interrelated with the immune system, contributing to local and systemic homeostasis, especially in tissues with high constitutive rates of apoptosis. Accumulating studies have indicated that immune dysregulation is associated with the pathogenesis of the female reproductive system, which causes preeclampsia (PE), recurrent spontaneous abortion (RSA), ruptured ectopic pregnancy, and so on. And some studies have revealed the pleiotropic and essential role of efferocytosis in these obstetrical disorders.

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Unlabelled: Impaired NK cell cytotoxic activity contributes to the local dysfunctional immune environment in endometriosis (EMS), which is an estrogen-dependent gynecological disease that affects the function of ectopic endometrial tissue clearance. The reason for the impaired cytotoxic activity of NK cells in an ectopic lesion microenvironment (ELM) is largely unknown. In this study, we show that the macroautophagy/autophagy level of endometrial stromal cells (ESCs) from EMS decreased under negative regulation of estrogen.

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In this study, the complete 17,809 bp mitochondrial genome of (F.) (Coleoptera: Chrysomelidae: Bruchinae) was sequenced using Illumina's HiSeq2000 platform. The mitogenome is a double-stranded circular molecule of 17,809 bp in length with 21 transfer RNA genes, 13 protein-coding genes, and two ribosomal RNA genes as in other insects.

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Problem: To explore whether IL-33/ST2 axis modulates the polarization and efferocytosis of decidual macrophages (dMφs).

Method Of Study: The phenotype characteristics of dMφs from both normal pregnant women and recurrent spontaneous abortion (RSA) patients were determined by real-time polymerase chain reaction (RT-PCR) and flow cytometry (FCM). Then, the efferocytosis and expression of IL-33 and its receptor (ST2) in dMφs were analyzed by FCM.

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Our previous study demonstrated that thymic stromal lymphopoietin (TSLP) secreted by cervical cancer cells promotes angiogenesis and recruitment, and regulates the function of eosinophils (EOS). However, the function of TSLP in the crosstalk between EOS and vascular endothelial cells in cancer lesions remains unknown. The aim of the present study was to investigate the effect of EOS caused by TSLP in angiogenesis of human umbilical vein endothelial cells (HUVECs).

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We present a new collusion attack to a kind of quantum secret sharing schemes with entangled states. Using this attack, an unauthorized set of agents can gain access to the shared secret without the others' cooperation. Furthermore, we establish a general model for this kind of quantum secret sharing schemes and then give some necessary conditions to design a secure quantum secret sharing scheme under this model.

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Endometriosis is an estrogen-dependent inflammatory disease. The anti-inflammatory cytokine IL-10 is also increased in endometriosis. IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses.

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Macrophages play an important role in the origin and development of endometriosis. Estrogen promoted the growth of decidual stromal cells (DSCs) by downregulating the level of interleukin (IL)-24. The aim of this study was to clarify the role and mechanism of IL-24 and its receptors in the regulation of biological functions of endometrial stromal cells (ESCs) during endometriosis.

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In this study, the complete 15,911 bp mitochondrial genome (mitogenome) of was sequenced. To estimate the status of , all available mitogenomes of were downloaded from GenBank for phylogenetic analysis. Phylogenetic analyses showed that , , , and three sequences formed a well-supported clade with very short terminal branch lengths, indicting the relatively close evolutionary relationships of these taxa.

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Endometriosis (EMS) is associated with an abnormal immune response to endometrial cells, which can facilitate the implantation and proliferation of ectopic endometrial tissues. It has been reported that human endometrial stromal cells (ESCs) express interleukin (IL)15. The aim of our study was to elucidate whether or not IL15 regulates the cross talk between ESCs and natural killer (NK) cells in the endometriotic milieu and, if so, how this regulation occurs.

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