Serovars and antimicrobial resistance profiles of Actinobacillus pleuropneumoniae isolates from clinical-case pigs in Taiwan.

Background: Pleuropneumonia remains an important challenge to swine production worldwide. The causative agent, Actinobacillus pleuropneumoniae serovar prevalence in countries can change over time. Few Taiwanese A.

Co-circulation of lineage 1 and lineage 3 porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2) in Taiwan during 2018-2024.

Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major concern in swine production. This study investigates the molecular epidemiology of lineage 1 and lineage 3 PRRSV-2 in Taiwan between 2018 and 2024. A total of 43,977 samples were collected across 15 counties in Taiwan, and 13,611 tested positive for PRRSV by real-time PCR.

Dynamic alterations of the intestinal microbiome and metabolome during transmissible gastroenteritis virus infection in weaned pigs.

Transmissible gastroenteritis virus (TGEV) infection induces diarrhea in piglets by targeting the small intestine, especially the jejunum and ileum. However, dynamic changes in the gut microbiota and metabolome during TGEV infection remain unclear. This study investigated these alterations and their association with intestinal damage in weaned pigs during early TGEV infection.

The Evaluation of a Porcine Circovirus Type 2 (PCV2) Intradermal Vaccine Against a PCV2 Field Strain.

Porcine circovirus type 2 (PCV2) has a major impact on swine productivity. Vaccines are used to aid in control and mitigate production losses. We investigated the protection provided by an intradermal PCV2 vaccine against a field strain in Taiwan.

Field Evaluation of a Ready-to-Use Porcine Circovirus Type 2 and Vaccine in Naturally Infected Farms in Taiwan.

Porcine circovirus type 2 (PCV2) and (MHP) are both important and common pathogens in the pig industry. Both pathogens are major contributors to the porcine respiratory disease complex and serve to potentiate other bacterial infections such as . This study aims to evaluate the efficacy of a ready-to-use bivalent PCV2 and MHP vaccine in the field under naturally PCV2-infected farms against existing monovalent options.

Comparison of antimicrobial susceptibility of Glaesserella parasuis from different pig production systems in Taiwan between 2015 and 2020.

Background: Glässer's disease, caused by Glaesserella parasuis (G. parasuis), is a widespread bacterial infection in swine that leads to significant economic losses. G.

New scoring system for the evaluation obstructive degrees based on computed tomography for obstructive colorectal cancer.

Background: The degree of obstruction plays an important role in decision-making for obstructive colorectal cancer (OCRC). The existing assessment still relies on the colorectal obstruction scoring system (CROSS) which is based on a comprehensive analysis of patients' complaints and eating conditions. The data collection relies on subjective descriptions and lacks objective parameters.

Lineage 7 Porcine Reproductive and Respiratory Syndrome Vaccine Demonstrates Cross-Protection Against Lineage 1 and Lineage 3 Strains.

: Porcine reproductive and respiratory syndrome virus (PRRSV) has a major impact on swine productivity. Modified-live vaccines (MLVs) are used to aid in control. We investigated the cross-protection provided by a lineage 7 PRRSV MLV against a lineage 1 isolate under laboratory conditions and a lineage 3 challenge under field conditions in Taiwan.

Pathotyping and molecular serotyping of clinical isolates of Glaesserella parasuis in Taiwan.

Glaesserella parasuis is a bacterial pathogen that causes severe economic losses in the swine industry worldwide. In this study, 262 G. parasuis isolates from pigs with Glässer's disease obtained between 2015 and 2022 in Taiwan were serotyped, pathotyped, and analyzed for virulence genes.

Pathogenicity and antigenic characterization of a novel highly virulent lineage 3 porcine reproductive and respiratory syndrome virus 2.

Background/purpose: Porcine reproductive and respiratory syndrome virus (PRRSV) is a pathogen with a negative economic impact on the global swine industry. In 2019, a suspected highly pathogenic strain, NPUST-108-929/2019 (108-929), was isolated from a pig farm in Pingtung with an outbreak of high mortality and analyzed. The characteristics of PRRSV 108-929 have barely been studied.

Isolation and evaluation of the pathogenicity of a hybrid shiga toxin-producing and Enterotoxigenic Escherichia coli in pigs.

Background: Porcine pathogenic Escherichia coli (E. coli), the globally recognized important pathogen, causes significant economic loss in the field. Enterotoxigenic E.

Molecular detection of emerging in Taiwan.

type (PCV) 2 is an important pathogen that has been circulating worldwide and has cuased serious economic loss in pig industry. However, both PCV3 and PCV4 are newly emerging viruses. In Taiwan, PCV2 has been one of the critical pathogens in pig frams and PCV3 has been detected since 2016; however, the epidemiolog of PCV3 in Taiwan remains unclear and PCV4 has yet to be identified.

Combination of an enzyme-linked immunosorbent assay and an indirect fluorescence assay for a nationwide sero-survey of Toxoplasma gondii infection in pig herds in Taiwan.

Toxoplasma gondii is a zoonotic pathogen that can infect farm animals, companion animals, and humans, sometimes causing public health issues. In Taiwan, the pig industry is a vital agricultural industry, with a self-sufficiency rate of 91 %, and pigs are also food-producing animal reservoirs of Toxoplasma gondii. Infected pigs are usually asymptomatic, and abortions and death may occur in severe cases.

Antimicrobial susceptibility and resistome of in Taiwan: a next-generation sequencing analysis.

infection causes a high mortality rate in porcine animals. Antimicrobial resistance poses global threats to public health. The current study aimed to determine the antimicrobial susceptibilities and probe the resistome of in Taiwan.

Antimicrobial resistance profile in Salmonella enterica serovar Choleraesuis isolates from diseased pigs in Taiwan.

This study investigated antimicrobial resistance in Salmonella enterica serovar Choleraesuis (S. Choleraesuis) isolates from diseased pigs in Taiwan (2015-2020). Among 272 isolates, florfenicol (96.

Hormone, Targeted, and Combinational Therapies for Breast Cancers: From Humans to Dogs.

Breast cancer (BC) is the most frequent cancer in women. In female dogs, canine mammary gland tumor (CMT) is also the leading neoplasm. Comparative oncology indicates similar tumor behaviors between human BCs (HBCs) and CMTs.

Genetic diversity and relatedness of feline parvovirus in Vietnam and its potential implications for canine-feline transmission.

Feline panleukopenia, caused by feline parvovirus (FPV), has been studied worldwide, but there have been very few studies conducted in Vietnam. In this study, 19 rectal swab samples were collected from northern Vietnam in 2018-2019 and screened for the presence of FPV using PCR. Through sequence analysis of the full-length VP2 gene, it was found that the FPV strains detected in Vietnam were closely related to those obtained from dogs in Vietnam, Asia, Europe, and America.

Chromogenic hybridization technique for detecting porcine circovirus 3 in lung and lymphoid tissues.

Background And Aim: Porcine circovirus 3 (PCV3) was recently reported in Malaysian commercial pig population in 2020 by conventional polymerase chain reaction (PCR), revealing a molecular prevalence of 17.02% in the sampled domestic pig population. This study aims to describe a chromogenic in situ hybridization (ISH) technique using digoxigenin (DIG)-labeled cloned PCV3 open reading frame 1 (ORF1) fragment DNA to detect and localize the PCV3 antigen in formalin-fixed, paraffin-embedded lung, and lymphoid tissue specimens.

Molecular Characteristics and Pathogenicity of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) 1 in Taiwan during 2019-2020.

Two variants of porcine reproductive and respiratory syndrome virus (PRRSV), PRRSV 1 and PRRSV 2, have caused abortion in pregnant sows and respiratory distress in nursery pigs worldwide. PRRSV 2 has been thoroughly researched in Taiwan since 1993; however, the first case of PRRSV 1 was not reported until late 2018. To decipher the genetic characteristics of PRRSV 1 in Taiwan, open reading frame 5 (ORF5) genes of PRRSV 1 strains collected from 11 individual pig farms in 2019-2020 were successfully sequenced.

Clinical characteristics of naturally Babesia gibsoni infected dogs: A study of 60 dogs.

Babesia gibsoni is increasingly recognized globally as a cause of canine tick-borne anemic disease; however, only a few clinical reports of naturally acquired infection are available. In this systematic study of dogs presenting with B. gibsoni infection, clinical and laboratory data were collected for dogs with PCR-confirmed B.