Evaluation of the Antidiabetic Potential of Methanolic Extract of Compared to Metformin in Streptozotocin-induced Diabetic Rats.

Background: Diabetes mellitus is a prevalent metabolic disorder characterized by reduced insulin activity leading to hyperglycemia, affecting over 425 million people globally. Traditional treatments, including sulfonylureas and biguanides, often have undesirable side effects, prompting a shift toward herbal remedies for diabetes management and prevention.

Objective: This study aims to evaluate the antidiabetic effects of budding leaves from compared to metformin in preventing streptozotocin (STZ)-induced hyperglycemia in rats.

BioArchLinux: community-driven fresh reproducible software repository for life sciences.

Motivation: The BioArchLinux project was initiated to address challenges in bioinformatics software reproducibility and freshness. Relying on Arch Linux's user-driven ecosystem, we aim to create a comprehensive and continuously updated repository for life sciences research.

Results: BioArchLinux provides a PKGBUILD-based system for seamless software packaging and maintenance, enabling users to access the latest bioinformatics tools across multiple programming languages.

Exploring the Interplay of Smoking Behavior, Heart Rate Variability, Pulmonary Function Test Results, Diabetes, and Mood Disorders: A Systematic Review.

This systematic review aimed to collate and analyze findings from various studies that explored the associations between heart rate variability (HRV), smoking behavior, pulmonary function, diabetes, and mood disorders. A comprehensive database search strategy was employed, utilizing medical subject headings terms combined with Boolean operators across seven databases. The review found that conditions such as hypertension and type 2 diabetes exacerbate cardiac autonomic dysfunction, thereby aggravating cardiovascular risks.

A Randomized Controlled Trial to Compare the Effectiveness of Smart Dynamic Fabric Actuator with Exercises in Chronic Musculoskeletal Leg Pain Associated with Prolonged Standing in a Hospital Setting.

Background: There are adverse effects on the health outcomes of workers whose occupation involves prolonged standing, such as lower back pain, leg pain, cardiovascular diseases, fatigue, discomfort, and pregnancy-related health outcomes. The effectiveness of massage therapy as an intervention for managing leg pain associated with prolonged standing needs to be addressed.

Aims: This study aimed to evaluate the smart dynamic fabric actuator's effectiveness in treating chronic musculoskeletal leg pain in persons with occupations involving prolonged standing.

Histiocytic lesion masquerading as papillary carcinoma thyroid-A case report.

Langerhans cell histiocytosis (LCH) is a rare clonal neoplasm derived from Langerhans-type cells that express CD 1a, langerin, and S 100 on immunohistochemistry. LCH usually involves multiple sites and multiple systems or multiple sites in a single system. Solitary LCH commonly involves the bones (especially the skull), lymph nodes, skin, and lungs.

Evaluating the Role of Glycemic Control in Modulating Pulmonary Function Among Smokers With Diabetes Mellitus: A Systematic Review.

Background: Diabetes mellitus (DM) impacts multiple body systems, including lung function, and this impact can be further complicated by smoking. The connection between blood sugar control and lung health in individuals with diabetes who smoke has been extensively studied, but findings have been varied. This systematic review sought to compile and assess the research on how blood sugar control influences lung function in smokers with diabetes.

Reaching High Piezoelectric Performance with Rotating Directional-Field-Aligned PVDF-MoS Piezo-Polymer Applicable for Large-Area Flexible Electronics.

Wearable electronics and smart harvesting textile studies require a material system that resists physical stimulation. Such applications require receptive piezo-polymers, and their activation-free preparation that can translate into a continuous large-area film. In this work, it is discussed whether the β-content of piezo-polymer is extended with no use of any activation (i.

Machine learning based quantification of VOC contribution in surface ozone prediction.

The prediction of surface ozone is essential attributing to its impact on human and environmental health. Volatile organic compounds (VOCs) are crucial in driving ozone concentration; particularly in urban areas where VOC limited regimes are prominent. The limited measurements of VOCs, however, hinder assessing the VOC-ozone relationship.

Large scale text mining for deriving useful insights: A case study focused on microbiome.

Text mining has been shown to be an auxiliary but key driver for modeling, data harmonization, and interpretation in bio-medicine. Scientific literature holds a wealth of information and embodies cumulative knowledge and remains the core basis on which mechanistic pathways, molecular databases, and models are built and refined. Text mining provides the necessary tools to automatically harness the potential of text.

A study of Factors Affecting Dialysis Recovery Time in Haemodialysis Patients in India.

Background: Patients on maintenance haemodialysis (MHD) often complain of fatigue and tiredness following haemodialysis sessions leading to poor compliance with the dialysis schedule. There is limited Indian data on dialysis recovery time (DRT). The present study was designed to assess the factors affecting DRT in our haemodialysis population.

Comparative transcriptome profiling of pomegranate genotypes having resistance and susceptible reaction to pv. .

Pomegranate ( L.) is an important fruit crop, rich in fiber, vitamins, antioxidants, minerals and source of different biologically active compounds. The bacterial blight caused by pv.

Dataset of sodium chloride sterile liquid in bottles for intravenous administration and fill level monitoring.

We propose a dataset to investigate the relationship between the fill level of bottles and tiny machine learning algorithms. Tiny machine learning is represented by any Artificial Intelligence algorithm (spanning from conventional decision tree classifiers to artificial neural networks) that can be deployed into a resource constrained micro controller unit (MCU). The data presented has been originally collected for a joint research project by STMicroelectronics and Sesovera.

Ectopic Expression of a Cell-Wall-Degrading Enzyme-Induced Leads to Resistance against Bacterial and Fungal Infection in .

Pathogen secreted cell-wall-degrading enzymes (CWDEs) induce plant innate immune responses. The expression of rice transcription factor () is enhanced in leaves upon treatment with different CWDEs and upon wounding. Ectopic expression of in leads to induction of immune responses such as callose deposition and upregulation of both salicylic acid- and jasmonic acid/ethylene-responsive defense genes.

Shape Memory Polyurethane-Based Smart Polymer Substrates for Physiologically Responsive, Dynamic Pressure (Re)Distribution.

Shape memory polymers (SMPs) are an exciting class of stimuli-responsive smart materials that demonstrate reactive and reversible changes in mechanical property, usually by switching between different states due to external stimuli. We report on the development of a polyurethane-based SMP foam for effective pressure redistribution that demonstrates controllable changes in dynamic pressure redistribution capability at a low transition temperature (∼24 °C)-ideally suited to matching modulations in body contact pressure for dynamic pressure relief (e.g.

RNA-Seq Revealed Expression of Many Novel Genes Associated With Persistence and Clearance in the Host Macrophage.

Host- as well as parasite-specific factors are equally crucial in allowing either the parasites to dominate, or host macrophages to resist infection. To identify such factors, we infected murine peritoneal macrophages with either the virulent (vAG83) or the non-virulent (nvAG83) parasites of . Then, through dual RNA-seq, we simultaneously elucidated the transcriptomic changes occurring both in the host and the parasites.

Noninvasive Sweat-Based Diagnosis of Visceral Leishmaniasis and Post Kala-Azar Dermal Leishmaniasis.

The diagnosis of visceral leishmaniasis (VL) is one of the foremost barriers in the control of this disease, as demonstration of the parasite by splenic/bone marrow aspiration is relatively difficult and requires expertise and laboratory support. The aim of the present study was to find a noninvasive diagnostic approach using the existing recombinant kinesine-39 (rK-39) immunochromatographic nitrocellulose strips test (ICT) with a human sweat specimen for the diagnosis of VL. The investigation was carried out on specimens (blood, sweat, and urine) collected from 58 confirmed VL, 50 confirmed post kala-azar dermal leishmaniasis (PKDL), 36 healthy control, and 35 patients from other diseases.

Designing of advanced smart medical stocking using stress-memory polymeric filaments for pressure control and massaging.

Compression treatment for the patients with chronic disorders such as venous ulcers and varicose veins needs the proper and adequate level of pressure sustainability. This has been a great challenge for health practitioners and stocking manufacturers even till today. There is an imperious need of any research, where internal compression pressure can be controlled or readjusted externally.

Sarcomatoid Carcinoma of Renal Pelvis with Abundant Heterologous Osteosarcomatous Element: A Case Report.

A 47-year-old male presented with haematuria and flank pain for two weeks. Ultrasonography and renal scan revealed a poorly functioning left kidney with multiple calculi. Simple nephrectomy was performed and the specimen revealed a mass in his renal pelvis which showed both carcinomatous and sarcomatous components on microscopy.

Stress-memory polymeric filaments for advanced compression therapy.

Shape memory polymers are stimulus responsive smart materials that can be applied in several forms such as films, fibers, and foams for a wide range of applications. Novel stress-memory behavior at a fiber level is yet to be uncovered, which would be favorable to control stress in the broad horizon of smart materials for numerous functions. In this work, a semi-crystalline segmented polyurethane was synthesized to prepare filaments/fibres and films.

Gaucher's Disease: A Rare Case, Diagnosed By Fine Needle Aspiration Cytology.

Fine Needle Aspiration (FNA) is a simple, inexpensive and innocuous diagnostic tool. It is increasingly accepted in daily medical practice. We report a case of Gaucher's disease diagnosed by FNA of enlarged spleen in a seven-year-old male presented with complaints of fever, on and off irregular bowel habits, abdominal distension and asymmetric gaze for four years and decreased vision in night for last one year.

Smart medical stocking using memory polymer for chronic venous disorders.

Proper level of pressure or compression generated by medical stocking or hosiery is the key element for successful treatment or management of chronic venous disorders such as oedema, leg ulcers, etc. However achieving the recommended compression level and, more importantly, sustaining it using stockings has been a major challenge to the health practitioners supervising the treatment. This work aims to investigate and design a smart compression stocking using shape-memory polymer that allows externally controlling the pressure level in the wrapped position on the leg.

Comfort and compressional characteristics of padding bandages.

Background: Padding bandage is an essential component of the multi-layer compression system used for chronic venous management. Padding plays a critical role in managing pressure over bony prominences and ensuring uniform pressure distribution around the limb circumference. Moreover, it helps in the management of heat, moisture and body fluids or exudates during the course of treatment to provide comfort to the patients.

Liquid transmission characteristics of padding bandages under pressure.

Padding is an essential component in a multilayer compression bandaging system, used inside the compression bandage through which substantial amount of pressure is exerted on the limb of patient for treatment of venous leg ulcers. As a result, the liquid transmission behavior of padding is also critical in managing body fluids or sweat exuded from the affected limb, reducing the excessive moisture build-up around the wound and thereby ensuring comfort to and hence a better compliance from the patients. This study investigates the in-plane fluid transport characteristics of needle-punched nonwoven padding bandages.

Virilizing cystic juvenile granulosa cell tumour of the ovary: a case report.

We report a rare case of virilizing cystic juvenile granulosa cell tumour of the ovary diagnosed by histopathological examination in a 17-year-old female presented with mass abdomen for two months, growing of the hairs on the face and abdomen and deepening of voice for one year.

Axillary schwannoma with extensive cystic degeneration.

Schwannoma affect mainly head, neck, and flexor aspect of the limbs. Neurogenic tumors arising from the brachial plexus are rare and axillary schwannoma is extremely uncommon. Cystic degeneration is common in longstanding cases and which when aspirated may yield only macrophages or lymphocytes leading to false diagnosis of the case in spite of strong clinical suspicion.