Publications by authors named "Basharat Ali"

Cadmium (Cd) contamination severely impairs plant productivity, necessitating effective mitigation strategies. This study investigated the efficacy of strigolactone-conjugated silica nanoparticle (SL-SiO NPs) in regulating Cd-toxicity in Brassica napus L. Foliar application of SL-SiO NPs decreased Cd accumulation (28-22 % in leaves and roots) through enhanced cell wall sequestration, while improving plant height and leaf area.

View Article and Find Full Text PDF

Cadmium (Cd) pollution is a persistent problem in the agricultural sector. Plants can be treated with nanoparticles (NP) to reduce heavy metal stress. MXene nanoparticles (MX-NPs) were tested for wheat Cd stress relief.

View Article and Find Full Text PDF

Background: Diabetes mellitus (DM) is a chronic metabolic disorder that seeks treatment instead of available mitigative therapy.

Methods: Six (E)-3-(aryl)-1-phenylprop-2-en-1-one chalcones were synthesized and characterized through various spectroscopic techniques. Their anti-diabetic potential was examined through in-vitro (α-glucosidase and α-amylase inhibition assays), in-vivo (alloxan-induced hyperglycemia), and in-silico studies.

View Article and Find Full Text PDF

Iron is a critical determinant in the development of drug tolerance in Candida albicans. Several genes essential for iron acquisition, transport, and regulation have been studied. Previous studies have shown that growth in an iron-limited medium alters the lipid compositions of C.

View Article and Find Full Text PDF

We developed a sensitive voltammetric sensor for detecting aromatic phenylenediamine (PD) isomers: -phenylenediamine (-PD), -phenylenediamine (-PD), and -phenylenediamine (-PD). This sensor uses a screen-printed graphene electrode (SPGE) modified with a new spin crossover (SCO) Fe-complex [Fe(salEen-5-I)]NCS 1. The structure of 1·0.

View Article and Find Full Text PDF

Clinical isolates of Candida auris show a high prevalence of resistance to Amphotericin B (AmB)-an uncommon trait in most Candida species. Alterations in ergosterol biosynthesis can contribute to acquired AmB resistance in C. auris laboratory strains but are rarely seen in clinical isolates.

View Article and Find Full Text PDF

The intrinsic resistance of Candidozyma auris (C. auris) to antifungal drugs poses a major therapeutic challenge, with conventional resistance mechanisms providing only partial explanations. Sphingolipids (SLs), known for their interclade heterogeneity, play a crucial role in antifungal resistance.

View Article and Find Full Text PDF

Despite the prevalence of dermatophytosis which affects a quarter of the world's population, there is a pressing need for innovative and effective treatment strategies. Targeting lipid structures and their biosynthetic pathways has emerged as a promising approach to combat antimicrobial drug-resistant cases. However, our knowledge of Trichophyton-related lipids is rather limited.

View Article and Find Full Text PDF

Lead (Pb), a toxic metal, causes severe health hazards to both humans and plants due to environmental pollution. Biochar addition has been efficiently utilized to enhance growth of plants as well as yield in the presence of Pb-induced stress. The present research introduces a novel use of biochar obtained from the weed Achyranthes japonica to enhance the growth of plants in Pb-contaminated soil.

View Article and Find Full Text PDF

A thriving agricultural system is the cornerstone of an expanding economy of agricultural countries. Farmers' crop productivity is significantly reduced when they choose the crop without considering environmental factors and soil characteristics. Crop prediction enables farmers to select crops that maximize crop yield and earnings.

View Article and Find Full Text PDF

Certain species of Mucorales have been identified as causative agents of mucormycosis, a rare yet often lethal fungal infection. Notably, these fungi exhibit intrinsic resistance to common azole drugs, which target lipids. Given the pivotal role of lipids in drug resistance and their contribution to innate resistance to azoles, this study provides a comprehensive overview of key lipid classes, including sphingolipids (SLs), glycerophospholipids (GPLs), and sterols, in 99-880, a well-characterized reference strain among Mucorales.

View Article and Find Full Text PDF

The Ciprofloxacin (CIP) toxicity and salinity stress in agricultural soils cause risk to environmental and food safety. Consequently, it is essential to devise or use more effective techniques for mitigating salinity and ciprofloxacin-induced stress in soil. This study includes the nZVI-loaded biochar synthesis, integrating the unique characteristics of raw biochar with nZVI.

View Article and Find Full Text PDF

The intensified concerns related to agrochemicals' ecological and health risks have encouraged the exploration of microbial agents as eco-friendly alternatives. Some members of spp. are potential plant-growth-promoting agents and benefit numerous crop plants globally.

View Article and Find Full Text PDF

Brassica napus is a well-known allopolyploid oil crop with high commercial potential. Gibberellin oxidase (GAox) is an essential enzyme that activates gibberellins, which regulate plant growth, and development, and have a significant impact on plant responses to abiotic stress. However, the comprehensive understanding of GAox genes and their evolution in Brassica plants remains elusive.

View Article and Find Full Text PDF

Silicon (Si) can significantly improve the salt tolerance of plants, but its mechanism remains unclear. In this study, role of abscisic acid (ABA) in Si derived salt resistance in tobacco seedling was investigated. Under salt stress, the photosynthetic rate, stomatal conductance, and transpiration rate of tobacco seedlings were reduced by 86.

View Article and Find Full Text PDF

Soil salinization is a serious concern across the globe that is negatively affecting crop productivity. Recently, biochar received attention for mitigating the adverse impacts of salinity. Salinity stress induces osmotic, ionic, and oxidative damages that disturb physiological and biochemical functioning and nutrient and water uptake, leading to a reduction in plant growth and development.

View Article and Find Full Text PDF
Article Synopsis
  • Celiac disease (CD) is an autoimmune disorder triggered by gluten sensitivity, previously thought to only affect white Europeans, but now recognized in various racial groups including South Asians and Africans.
  • Recent research focused on genetic variations LPP rs1464510 and ZMIZ1 rs1250552 in the Punjabi Pakistani population, revealing significant associations with CD risk.
  • Findings indicated that the LPP rs1464510 A allele reduces CD risk by approximately 52%, while having the C allele increases risk by about 2.6 times; similarly, the AG genotype of rs1250552 decreases risk by 73%.
View Article and Find Full Text PDF

Numerous studies shown that silicon (Si) enhanced plants' resistance to cadmium (Cd). Most studies primarily focused on investigating the impact of Si on Cd accumulation. However, there is a lack of how Si enhanced Cd resistance through regulation of water balance.

View Article and Find Full Text PDF

Cigarette butts, often discarded as litter, are considered a common form of waste, containing a variety of pollutants within this hazardous residue. This study, which was designed to assess the environmental release of certain metals from cigarette butts, investigates a variety of scenarios under varying climatic conditions. Thus, in order to assess the level of metal contamination, samples of cigarette butts were collected in urban areas from seven popular brands in China, smoked artificially, and examined through graphite furnace atomic absorption (GF-AAS).

View Article and Find Full Text PDF

Broomrape (Orobanche cumana) negatively affects sunflower, causing severe yield losses, and thus, there is a need to control O. cumana infestation. Brassinosteroids (BRs) play key roles in plant growth and provide resilience to weed infection.

View Article and Find Full Text PDF

Beneficial plant microbes can enhance the growth and quality of field crops. However, the benefits of microbes using cheap and efficient inoculation methods are still uncommon. Seed coating with biocontrol agents can reduce the amount of inocula along with having the potential for large-scale application.

View Article and Find Full Text PDF

The objective of the study was to evaluate the performance of Pistia stratiotes for treatment of domestic wastewater in a free surface water flow constructed wetland. The objective of the study was to evaluate contaminants removal efficiency of the constructed wetland vegetated with P. stratiotes in treatment of domestic wastewater against Hydraulic retention time (HRT) of 10, 20 and 30 days was investigated.

View Article and Find Full Text PDF

Chromium is a serious heavy metal (HM) and its concentration in plant-soil interface is soaring due to anthropogenic activities, unregulated disposals, and lack of efficient treatments. High concentration of Cr is toxic to ecosystems and human health. Cr stress also diminishes the plant performance by changing the plant's vegetative and reproductive development that ultimately affects sustainable crop production.

View Article and Find Full Text PDF

In this study, we explored the sphingolipid (SL) landscape in Candida auris, which plays pivotal roles in fungal biology and drug susceptibility. The composition of SLs exhibited substantial variations at both the SL class and molecular species levels among clade isolates. Utilizing principal component analysis, we successfully differentiated the five clades based on their SL class composition.

View Article and Find Full Text PDF