Impact of forced diuresis at two different time points on pelvic imaging in prostatic carcinoma with 68 Ga-PSMA PET/CT.

Objective: We compared diagnostic quality of 68 Ga-PSMA PET/CT imaging focused on the pelvic structures using two furosemide protocols in two different groups of patients.

Material And Methods: A total of 55 patients with prostate cancer were retrospectively enrolled in the study. Out of 55, 31 patients were in group 1 (median age: 66 years, Range 44-78 years) in which furosemide injection was given after completion of whole-body 68 Ga-PSMA PET/CT scan and 24 patients were in group 2 (median age: 63.

Two new cycloartane type triterpenes from .

is an important medicinal plant known for various biological activities like anti-inflammatory, CNS depressants, contraceptive, analgesic, immunomodulatory, antimalarial, antifeedant, leishmanicidal and antiviral. It is a rich source of rohitukine, a basic skeleton of flavopiridol. Phytochemical investigation of chloroform extracts of leaves, lead to the isolation of beddomeilactone () and two new cycloartane type triterpenoids beddomeilactol () and binectarilactone-A ) with modified A ring.

Automated Detection of Poor-Quality Scintigraphic Images Using Machine Learning.

 In the present study, we have used machine learning algorithm to accomplish the task of automated detection of poor-quality scintigraphic images. We have validated the accuracy of our machine learning algorithm on Tc-methyl diphosphonate ( Tc-MDP) bone scan images.  Ninety-nine patients underwent 99mTC-MDP bone scan acquisition twice at two different acquisition speeds, one at low speed and another at double the speed of the first scan, with patient lying in the same position on the scan table.

Optimum Value of Scale and Threshold for Compression of 99mTc-MDP Bone Scan Images using Wavelet Transform.

Introduction: Wavelet transforms of an image result in set of wavelet coefficients. Thresholding eliminates insignificant coefficients while retaining the significant ones (resulting in matrix having few nonzero elements that need to be stored). The compressed image is reconstructed by applying inverse wavelet transform.

Design and Evaluation of MeVisLab Networks for Co-Registration and Cropping of Positron Emission Tomography/Computed Tomography Scans.

Objective: The aim of the present study was to design and evaluate two MeVisLab networks, one for co-registration of positron emission tomography/computed tomography (PET/CT) images and second for cropping the co-registered PET/CT images.

Materials And Methods: Two MeVisLab networks, one to co-register and export PET/CT DICOM images and second for cropping the co-registered PET/CT images were designed using different modules of registration toolkit MERIT. One hundred and twenty-five PET/CT studies were exported from Siemens and GE scanners in DICOM format.

Prognostication Based on Texture Analysis of Baseline F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Nonsmall-Cell Lung Carcinoma Patients Who Underwent Platinum-Based Chemotherapy as First-Line Treatment.

Objective: Our study aims to establish the potential for tumor heterogeneity evaluated using F fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) texture analysis in nonsmall-cell lung carcinoma (NSCLC) patients who underwent platinum-based chemotherapy to provide an independent marker for overall survival (OS) of more than 1-year.

Materials And Methods: A total of 42 patients (34 male and 8 female) with biopsy-proven NSCLC and mean age 55.33 ± 10.

Haralick texture features extracted from Ga-68 PSMA PET/CT to differentiate normal prostate from prostate cancer: a feasibility study.

Objective: Role of texture parameters on the basis of Ga-68 PSMA PET/CT in prostate cancer (Pca) is largely unexplored. Present work done is a preliminary study that aims to evaluate the role of Haralick texture features on the basis of Ga-68 PSMA PET/CT in Pca in which texture features were used to differentiate between normal prostate and Pca tissue.

Methods: The study retrospectively enrolled patients in two groups: group 1 included 30 patients with biopsy-proven adenocarcinoma prostate and median age 64 years (range: 50-82 years) who underwent baseline Ga-68 PSMA PET/CT prior to therapy; group 2 included 24 patients with pathologies other than Pca and median age 53.

Utility of 18F-FDG-PET/CT in management and prognostication of treatment naïve late-stage soft tissue sarcomas.

Objective: This study evaluated the utility of 18F-fluorodexoyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in staging, grading, and prognostication of Stage III and IV soft tissue sarcomas (STSs).

Methods: Forty patients (Median age = 32.5 years; 25 men) with histologically proven STSs, prospectively underwent 18F-FDG-PET/CTs at baseline.

Is there a utility of adding skeletal imaging to 68-Ga-prostate-specific membrane antigen-PET/computed tomography in initial staging of patients with high-risk prostate cancer?

Purpose: Both bone-scan and cross-sectional imaging are indicated in the staging of high-risk prostate cancer (PCa). However, 68Ga-prostate-specific membrane antigen (PSMA)-PET/computed tomography (CT) has proven to be an excellent tracer for detection of skeletal metastases. The aim of this study was to assess if adding skeletal imaging (with 18F-Fluoride-PET/CT) to 68-Ga-PSMA-PET/CT had any impact on high-risk PCa staging.

Semi-quantitative F-18-FDG PET/computed tomography parameters for prediction of grade in patients with renal cell carcinoma and the incremental value of diuretics.

Objective: The primary objective of the study was to evaluate the correlation between semi-quantitative F-18 FDG PET parameters and renal cell carcinoma (RCC) grade and its role in predicting the histopathological grade in RCC. The secondary objective was to evaluate the role of forced diuresis in improving the diagnostic accuracy of F-18 FDG for RCC.

Methods: Thirty-three patients with radiologically proven RCC were included in the study.

Denoising of iodine-131 images using a median filter.

Objective: An iodine-131 (I) image visually appears to be contaminated with impulse noise. The two-dimensional median filter removes noise without sacrificing the edge information. Its performance depends on the shape and size of the mask.

Comparison of F18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and Dynamic Contrast-Enhanced Magnetic Resonance Imaging as Markers of Graft Viability in Anterior Cruciate Ligament Reconstruction.

Background: F18-fluorodeoxyglucose positron emission tomography/computed tomography (F18-FDG PET/CT) can be used to assess changes in the metabolism of an anterior cruciate ligament (ACL) graft as it is undergoing "ligamentization." Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is the preferred modality for noninvasive assessment of graft structure and graft vascularity.

Purpose: To compare the use of F18-FDG PET/CT and DCE-MRI to assess ligamentization within the ACL graft and correlate the results with clinical tests.

Standardization of image reconstruction parameters for dynamic fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography.

Aim: The present study aimed to standardize the ordered subset expectation maximization (OSEM) reconstruction parameters for a dynamic PET/CT study.

Participants And Methods: A locally fabricated phantom was filled with fluorine-18-fluorodeoxyglucose (F-FDG) for four different sphere to background ratios (SBRs), that is, 10 : 1, 8 : 1, 6 : 1, and 4 : 1, and dynamic PET/CT was acquired for 5 min. Transaxial slices were reconstructed using OSEM [full-width at half-maximum (FWHM): 1-7 mm and iterations: 1-8].

Role of Various Metabolic Parameters Derived From Baseline 18F-FDG PET/CT as Prognostic Markers in Non-Small Cell Lung Cancer Patients Undergoing Platinum-Based Chemotherapy.

Purpose: The aim of this study was to prospectively evaluate the role of various quantitative and semiquantitative metabolic parameters derived from dynamic and static baseline F-FDG PET/CT in prediction of overall survival (OS) in non-small cell lung cancer (NSCLC) patients who were planned to undergo platinum-based chemotherapy.

Methods: Sixty patients (51 male and 9 female patients) with biopsy-proven NSCLC and mean age 59.55 ± 10.

Role of various semiquantitative parameters of 18F-FDG PET/CT studies for interim treatment response evaluation in non-small-cell lung cancer.

Purpose: The aim of this study was to prospectively evaluate the role of various semiquantitative parameters obtained from fluorine-18 fluorodeoxyglucose (F-FDG) PET/CT in interim treatment response assessment in biopsy-proven non-small-cell lung cancer (NSCLC) and to find the best parameter, if any.

Materials And Methods: Totally, 32 patients (male/female: 25/7) with biopsy proven NSCLC and a mean age of 54.71±12.