Gender-specific assessment of lipid profiles correlation with serum uric acid in non-dialysis chronic kidney disease patients: Prospective observational cross-sectional study.

Background: Serum uric acid (SUA) serves as an important marker for assessing kidney function in chronic kidney disease (CKD) patients. Emerging reports suggest a potential relationship between SUA and dyslipidemia. The study aims to examine the correlation between SUA and lipid profiles in CKD population.

Prevalence and Risk Factors of Musculoskeletal Pain Among Pediatric Ophthalmologists and Strabismologists in the Middle East: A Cross-sectional Study.

Purpose: To assess the prevalence and risk factors of musculoskeletal pain among pediatric ophthalmologists and strabismologists in the Middle East, and their impact on their work.

Methods: A cross-sectional survey-based study was conducted using SurveyMonkey distributed via the social media WhatsApp platform among pediatric ophthalmologists and strabismologists in some countries of the Middle East. The survey captured demographics, clinical workload, ergonomic practices, musculoskeletal symptoms, risk factors, and treatment methods.

Epidemiology of Hepatitis B and C Infections in Al-Anbar/Iraq and Correlation Between Viral Load and Liver Function.

Hepatitis B (HBV) and C (HCV) represent a menacing health problem worldwide and its risk of contamination and transmission by routine activities and contact with infected patients and its remarkable adverse effects and presence of silent carriers. The diagnosis developed with the developing techniques using more specific techniques. The aim is to study the epidemiology and molecular detection of HBV and HCV in the Anbar governorate (Fallujah and Amiriyah) and the correlation between the viral load of HBV and HCV on liver functions.

Prevalence of dermatophyte infections in cats in Ramadi and Fallujah Cities, Iraq.

Background: Dermatophytosis, which is characterized by superficial infection of keratinized tissues, is the most frequent fungal disease in small animal veterinary medicine. Diagnosing dermatophytosis purely according to clinical indications is problematic because dermatological findings vary, and various other skin diseases resemble the characteristic fungal lesion.

Aim: This study aimed to detect the prevalence of dermatophytes in pet cats with skin lesions who presented to private veterinary clinics in Ramadi and Fallujah cities, Iraq.

Epidemiology and antibiotic resistance of . in pet dogs: Implications for public health.

Background: . are zoonotic pathogens that can be transmitted from pets and other animals to humans. The incidence of antibiotic-resistant strains poses a severe threat to both veterinary and public health.

Interplay between NETosis and the lncRNA-microRNA regulatory axis in the immunopathogenesis of cancer.

Neutrophil extracellular traps (NETs), web-like complex structures secreted by neutrophils, have emerged as key players in the modulation of immune responses and the immunopathogenesis of immune disorders. Initially described for their antimicrobial function, NETs now play a part in the fundamental processes of cancer biology, including cancer initiation, metastatic dissemination, and immune evasion strategies. NETs hijack anti-tumor immunity by entrapping circulating cancer cells, fostering the growth of tumors, and reorganizing the tumor microenvironment such that it is pro-malignancy.

NFĸB and its inhibitors in preeclampsia: mechanisms and potential interventions.

Preeclampsia (PE), which affects between 2 and 15% of pregnancies, is one of the most often reported prenatal problems. It is defined as gestational hypertension beyond 20 weeks of pregnancy, along with widespread edema or proteinuria and specific types of organ damage. PE is characterized by increased levels and activation of nuclear factor kappa B (NF-κB) in the mother's blood and placental cells.

Histomorphological evaluation of docetaxel effects on testes and epididymides in Wistar rats.

Background: Chemotherapy drugs, such as Docetaxel, which are crucial for treating cancer, frequently cause unknowingly damage to healthy tissues.

Aim: To investigate the histomorphological effects of docetaxel chemotherapy on certain parameters in testes and epididymides.

Method: For this purpose, 24 Wistar Albino rats were divided randomly into one control group and three treatment groups.

Efficacy of febuxostat on hyperuricemia and estimated glomerular filtration rate in patients with non-dialysis stage 3/4 chronic kidney disease and assessment of cardiac function: a 12-month interventional study.

Objectives: Febuxostat, an oral medication for treating hyperuricemia (HUA), is a non-purine xanthine oxidase inhibitor that regulates serum uric acid (SUA) metabolism in patients with chronic kidney disease (CKD). However, the drug's effectiveness in improving renal function in patients with non-dialysis stage 3/4 CKD remains unclear. Our aim is to investigate the efficacy of febuxostat on kidney function.

Engineered etching and laser treatment of porous silicon for enhanced sensitivity and speed of Pt/n-PSi/Pt UV photodetectors.

Silicon-based photodetectors offer notable advantages in cost, performance, and reliability. However, while nanoscale silicon (porous silicon, PSi) effectively emits visible light, it remains inefficient as an indirect-bandgap semiconductor. To improve its optoelectronic properties, coupling silicon with a wide-bandgap semiconductor is a promising strategy.

A novel obesity-prevention dietary score is associated with favorable metabolic status and lower blood pressure in obesity.

Background: Obesity is a major worldwide health problem and is associated with numerous diseases including diabetes, cardiovascular diseases, and some types of cancers. In the current cross-sectional study, we aimed to evaluate the association between a novel dietary obesity prevention score (DOPS) with metabolic parameters including serum lipid profile, glycemic markers, electrolyte status and blood pressure in individuals with obesity.

Methods: Three hundred and four individuals with obesity aged 18-65 years old were recruited through convenient sampling; anthropometric and dietary assessments were performed and blood pressure was measured.

The role of irisin in exercise-induced muscle and metabolic health: a narrative review.

Irisin, a myokine released during physical exercise, has emerged as a key mediator of muscle health and metabolic regulation. This review synthesizes current evidence on how aerobic exercise stimulates irisin release and its subsequent effects, including enhanced muscle mass, strength, and recovery. Additionally, irisin promotes the browning of white adipose tissue, improving fat metabolism and glucose regulation.

Flavonoids in the regulation of microglial-mediated neuroinflammation; focus on fisetin, rutin, and quercetin.

Neuroinflammation is a critical mechanism in central nervous system (CNS) inflammatory disorders, encompassing conditions such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), multiple sclerosis (MS), traumatic brain injury (TBI), encephalitis, spinal cord injury (SCI), and cerebral stroke. Neuroinflammation is characterized by increased blood vessel permeability, leukocyte infiltration, glial cell activation, and elevated production of inflammatory mediators, such as chemokines and cytokines. Microglia act as the resident macrophages of the central nervous system, serving as the principal defense mechanism in brain tissue.

A Low-Fouling Electrochemical Immunosensor Based On Metal-Organic Framework and Ternary Metal Oxide Nanomaterials Using Dual Signal Amplification Strategy for Sensitive Detection of Prostate-Specific Antigen (PSA) in Patient Samples.

A label-free electrochemical immunosensor based on the zeolitic imidazolate framework-8 (ZIF8)/bismuth ferrite (BFO) nanocomposite was fabricated for the specific and sensitive quantification of prostate-specific antigen (PSA). The ZIF8-BFO material not only increases the surface area effectively but also enhances the catalytic capability of the electrode through a dual amplification strategy, leading to the improved sensitivity of the probe for PSA recognition. A thin layer of l-cysteine was used for two reasons: providing a scaffold for the next functionalization and reducing the fouling of plasma ingredients on the surface of the probe.

Infection rate of canine parvovirus in dogs presented at private veterinary clinics in Baghdad city.

Background: Canine parvovirus is the primary etiology of hemorrhagic diarrhea and mortality in puppies worldwide.

Aim: This study was designed to investigate canine parvovirus in dogs in Baghdad by rapid testing.

Methods: Rectal swabs were collected from 864 dogs presenting at sixteen private veterinary clinics with clinical signs including vomiting, anorexia, nausea, and regurgitation.

Effects of edible bird's nest and EDTA on cadmium toxicity exposed rats' embryo production, quality, and pre- and post-embryo transfer pregnancy rates.

Objectives: The current study aimed to investigate the prophylactic potential of EBN compared to EDTA in mitigating Cd's toxic effects on pregnancy rates and embryonic development in rats.

Materials And Methods: Ninety-eight female rats (Sprague Dawley) were divided into donor and recipient groups, with donors further divided into seven subgroups, including negative control, Cd-exposed, EBN-treated, and EDTA-treated groups. Embryos from donors were transferred to recipient rats, with EBN and Cd administered for 4 weeks and EDTA given only in the last 5 days for the donor group.

Gender differences in the associations of adverse childhood experiences with depression and anxiety: A systematic review and meta-analysis.

Background: Gender differences in the associations of adverse childhood experiences (ACEs) with depression and anxiety, remain underexplored. We aimed to quantify and directly compare gender-specific associations between ACEs and depression and anxiety.

Methods: We systematically searched PubMed, Medline, and Embase for observational studies.

Marine life as a source of anti-prostate cancer agents: an updated overview (2003-2023).

Cancer is the deadliest threat that human beings are currently facing. Prostate cancer is the second largest cancer in males all over the world. During the last decade, scientists made breakthroughs in combatting this deadliest threat through naturally identified drugs.

The role of hyperuricemia in the progression of end-stage kidney disease and its molecular prospective in inflammation and cardiovascular diseases: A general review.

With the ongoing development of the Chinese economy, the occurrence of chronic kidney disease (CKD) has experienced a remarkable upsurge recently, and due to uremia caused by CKD, the number of patients undergoing dialysis has shown a dramatic increase. China has been ranked first in the world for patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) with approximately one million patients across the country. Due to the loss of kidney function caused by CKD, the kidneys tend to lose their ability to excrete uric acid (UA) out of the body; therefore, most patients undergoing dialysis are complicated with hyperuricemia (HUA).

Isolation and molecular identification of bacteria from sheep with eye infections.

Background: Ocular disease in sheep is a severe concern for the health and welfare of livestock animals, as well as losses of productivity and value to the livestock industry.

Aim: This study aimed to isolate and characterize bacteria in sheep with eye disease on the molecular level.

Methods: One hundred fifty sheep with eye infections were treated, and tissue samples were taken for microbiological studies.

Laser surface nanoalloying of Fe, Si, and C on aluminum substrates with excellent optical and electronic properties.

Laser surface alloying of Fe, Si, and C on aluminium is demonstrated using a Q-switched Nd:YAG laser as the source of energy. The fundamental wavelength of the laser beam was 1064 nm with an output energy of 100 mJ and a pulse duration of 10 ns. The exposure was conducted in repetitive mode with a frequency rate of 1 Hz.

The oncolytic effect of Newcastle disease virus attenuated AMHA1 strain against digestive system tumors.

Background And Aim: Malignant diseases are among the most common and deadly illnesses that are often spread due to lifestyle choices. These diseases are caused by unchecked cell growth, which can be curable if detected early. Cancer treatment is dependent on various internal and external factors.

The role and clinical implications of HIF-PHI daprodustat in dialysis-dependent and non-dialysis-dependent chronic kidney disease anemic patients: a general review.

Chronic kidney disease (CKD) patients often suffer from complications such as anemia as the kidney function declines. More than 25% of CKD hemodialysis patients in China are complicated with renal anemia due to renal and hepatic impairment in the production of erythropoietin (EPO). In recent years, prolyl hydroxylase domain (PHD) inhibitors have been approved in China and Japan for the treatment of CKD patients complicated with anemia.

The Role of Ozonated Jerusalem Artichoke Ointment on the Healing of Surgically Created Full-Thickness Cutaneous Wounds in Rabbits.

Jerusalem artichoke (J.A.) tubers contain compounds that exhibit anti-inflammatory effects and can minimize tissue damage.

Exosome-mediated Transfer of lncRNA in Liver Associated Diseases; Uncovered Truths.

Exosomes are extracellular vesicles with a diameter ranging from 40 to 160 nm. They are produced by hepatocytes, cholangiocytes, hepatic stellate cells (HSCs), liver sinusoidal endothelial cells (LSECs) and Kupffer cells in liver tissue. The secretion of exosomes might vary in quantity and composition in reaction to multiple triggers and various stages of disease.