Quercetin as a multi-targeted therapeutic agent in breast cancer: molecular targets and therapeutic potential.

Breast cancer is a worldwide serious health issue with constantly recurring issues of drug resistance, toxicity, and recurrence. These limitations have prompted research on various drug compounds, particularly those derived from plants. Quercetin is one such compound, a flavonol dietary component.

Anti-metastatic potential of flavonoids for the treatment of cancers: focus on epithelial-mesenchymal transition (EMT) process.

The leading factor contributing to patient mortality is the local invasion and metastasis of tumors, which are influenced by the malignant progression of tumor cells. The epithelial-mesenchymal transition (EMT) is key to understanding malignancy development. EMT is a critical regulatory mechanism for differentiating cell populations initially observed during the neural crest and embryonic gastrulation formation.

The role of irisin in exercise-induced muscle and metabolic health: a narrative review.

Irisin, a myokine released during physical exercise, has emerged as a key mediator of muscle health and metabolic regulation. This review synthesizes current evidence on how aerobic exercise stimulates irisin release and its subsequent effects, including enhanced muscle mass, strength, and recovery. Additionally, irisin promotes the browning of white adipose tissue, improving fat metabolism and glucose regulation.