Hydraulic constraints to stomatal conductance in flooded trees.

Stomatal closure is a pervasive response among trees exposed to flooded soil. We tested whether this response is caused by reduced hydraulic conductance in the soil-to-leaf hydraulic continuum (k), and particularly by reduced root hydraulic conductance (k), which has been widely hypothesized. We tracked stomatal conductance at the leaf level (g) and canopy scale (G) along with physiological conditions in two temperate tree species, Magnolia grandiflora and Quercus virginiana, that were subjected to flood and control conditions in a greenhouse experiment.

Ultrasonographic assessment of bypass capacity after revascularization surgery in moyamoya disease: a systematic review and single-arm meta-analysis.

Purpose: Moyamoya disease (MMD) is a chronic cerebrovascular disorder characterized by progressive arterial stenosis and fragile collateral formation, elevating stroke risk. Revascularization is the standard treatment, yet up to 27% of patients experience ischemic events within a year due to bypass insufficiency. While digital subtraction angiography (DSA) remains the gold standard for assessing bypass function, it is invasive and time-consuming.

The predictive value of the orientation and offset of angle α and angle κ for visual outcomes after trifocal intraocular lens implantation in an Asian cohort.

Purpose: To evaluate the predictive value of the preoperative orientation and offset of angle alpha(chord alpha) and angle kappa(chord mu) for visual outcomes in patients who underwent trifocal intraocular lens (IOL) implantation.

Methods: Patient records of eyes that underwent AT LISA tri 839MP implantation were retrospectively collected and grouped according to the preoperative offset and orientations of chord alpha and chord mu. The two-dimensional location of each angle was described by the interaction of the orientation and offset.

Clinical comparison of two surgical techniques in obtaining complete root coverage of single RT1 gingival recessions.

Objectives: This study aimed to compare the efficacy of the full-thickness palatal graft technique (FTPGT) and the coronally advanced flap with subepithelial connective tissue graft (CAF + SCTG) in achieving complete root coverage (CRC) in single gingival recessions (GR).

Methods: Forty healthy patients with a single RT1 GR were randomized into two groups: 20 treated with CAF + SCTG and 20 with FTPGT. Baseline and 12-month measurements of GR, keratinized tissue width (KTW), probing depth (PD), clinical attachment level (CAL), and gingival thickness (GT) were recorded.

Self-efficacy for cancer self-management in the context of COVID-19: a cross-sectional survey study.

Purpose: For cancer survivors, self-efficacy is needed to manage the disease and the effects of treatment. The COVID-19 pandemic disrupted cancer-related healthcare, which may have impacted self-management self-efficacy. We investigated self-efficacy reported by cancer survivors during COVID-19, including associations with healthcare disruptions, distress, and general health.

Alteration in hippocampal mitochondria ultrastructure and cholesterol accumulation linked to mitochondrial dysfunction in the valproic acid rat model of autism spectrum disorders.

Rationale: Autism spectrum disorders (ASD) are a group of neurodevelopmental and multifactorial conditions with cognitive manifestations. The valproic acid (VPA) rat model is a well-validated model that successfully reproduces the behavioral and neuroanatomical alterations of ASD. Previous studies found atypical brain connectivity and metabolic patterns in VPA animals: local glucose hypermetabolism in the prefrontal cortex, with no metabolic changes in the hippocampus.

Silicic acid seed pre-treatment modulates growth and antioxidant responses in maize under drought stress.

Drought stress is the most vulnerable abiotic factor affecting plant growth and yield. The use of silicic acid as seed priming treatment is emerging as an effective approach to regulate maize plants susceptibility to water stress. The study was formulated for investigating the effect of silicic acid seed priming treatment in modulating the oxidative defense and key physio-biochemical attributes of maize plants under drought stress conditions.

Trichotillomania and its treatment: an updated review and recommendations.

Introduction: Trichotillomania is an impulse control disorder in which individuals fail to resist urges to pull out their own hair and is associated with significant psychiatric comorbidity and functional impairment in affected children, adolescents, and adults. Onset in childhood or adolescence is typical, yet the literature on phenomenology, psychopathology, and treatment outcome involving pediatric samples remains particularly sparse. Efficacious treatments have been developed and found efficacious, most notably cognitive-behavioral interventions known collectively as habit reversal training, although relapse in adults appears to be somewhat common.

Losses to Follow-Up in a Nationally Representative Study of Community-Living Older Americans: Two Approaches to Censoring and Implications for Mortality Outcomes.

Background: In the National Health and Aging Trends Study (NHATS), use of its Sensitive files leads to incomplete ascertainment of mortality, largely because of losses to follow-up. To account for these losses, we compared two censoring approaches for evaluating mortality.

Methods: In a hybrid approach, most participants were censored at the time of last contact, while the remainder were censored at the time of last completed interview.

The effects of acidifying agents on the growth, antimicrobial resistance, and plasmid genome of Salmonella enterica serovar Infantis.

This study evaluated if acidifying agents used for ammonia control and pathogen reduction in poultry houses have a deleterious effect on the survival and growth of Salmonella Infantis. Changes in antimicrobial resistance (AMR) and pESI plasmid gene composition were also investigated. When S.

Tailoring supercapacitance and water splitting performance of nickel sulfides (NiS and NiS): a comparative study of colloidal and solventless synthesis.

To overcome the potential issue of active site blockage by surfactants in colloidal synthesis, alternative synthetic approaches must be explored. In this study, we investigated both solvent-free and colloidal thermolysis routes to synthesize nickel sulfides (NiS and NiS) using sulfur-based Ni complexes, [Ni(SCO(CH))] (Ni-Xan) and [Ni(SCN(CH))] (Ni-DTC) as precursors. The solvent-free decomposition of these complexes produced ligand-free NiS and NiS in the absence or presence of triphenylphosphine (TPP), respectively.

A Scoping Review of Implementation Science in Planning and Delivering Tobacco Control Interventions in the United States from 2000 to 2020: Frameworks, Intervention Characteristics, and Health Equity Considerations.

Introduction: Evidence-based interventions to reduce tobacco-related morbidity and mortality are not widely or effectively implemented, thereby failing to equitably address disparities in tobacco-related health outcomes. Implementation science (IS) has the potential to advance the impact of tobacco control programs, but its use in this field has not been previously explored. To identify opportunities for expanding tobacco intervention impact, this scoping review investigated the use of IS tools in tobacco control research in the United States.

Nasal microbiome inhabitants with anti- activity.

Unlabelled: (SA) colonizes most mammals but also represents a danger in clinical settings because it evolves resistance against antibiotics, and SA infections represent a leading cause of death worldwide. SA nasal carriage provides the bacterial reservoir for opportunistic infection because clinical strains often match the patient's own nasally carried strain. The global SA carriage rate is typically reported as 25%-30% after sampling subjects once or twice and defining carrier status using culture-based methods.

IBDV-SSA, a novel molecular approach for the recovery of infectious bursal disease virus whole genomes from FTA cards.

Infectious bursal disease (IBD), a highly contagious viral disease in young chickens, poses significant economic losses due to high mortality and immunosuppression. While IBD virus (IBDV) virulence is influenced by multiple genes, whole-genome sequencing (WGS) of IBDV is crucial for defining the strain pathotype and clinical profile. Flinders Technology Associates (FTA) cards are convenient for field sample collection, but their filter paper matrix can hinder nucleic acid recovery, impacting sequencing efficiency.

Late Loeys-Dietz Syndrome Diagnosis in an Adolescent With Severe Phenotype.

Background: Loeys-Dietz syndrome (LDS) is a rare connective tissue disorder (CTD) with musculoskeletal, craniofacial, and cardiovascular features with a prevalence of approximately 1:50,000. Morbidity and mortality often occur earlier in patients with LDS compared to patients with other CTDs.

Case Summary: We present a teenager with subacute heart failure, 4/6 holosystolic murmur with diastolic rumble, facial differences, and arachnodactyly.

First Transcatheter Pulmonary Valve Replacement in Tanzania: Feasibility of Advanced Cardiac Interventions in Resource-Limited Settings.

Background: Transcatheter pulmonary valve implantation (TPVI) has emerged as a viable alternative to surgical pulmonary valve replacement for patients with congenital heart disease and right ventricular outflow tract dysfunction. However, its adoption in low-resource settings has been limited.

Case Summary: We report the first successful TPVI procedures in Tanzania.

Improving Door-In-Door-Out Times for STEMI Transfer Patients: Impact of a Protocolized Autolaunch Process.

Background: The timely transfer of patients with ST-segment elevation myocardial infarction (STEMI) to percutaneous coronary intervention-capable centers is critical for improving outcomes. Although the American Heart Association recommends a door-in-door-out (DIDO) time of ≤30 minutes, national compliance remains low.

Project Rationale: At Harris Health, no patients with STEMI met this benchmark before 2022.

Improved Cardiac Structure and Ventricular-Arterial Coupling After Baroreflex Activation Therapy.

Baroreflex activation therapy (BAT) improves functional status, quality of life, and exercise capacity in patients with heart failure with reduced ejection fraction; however, its direct effects on reversing adverse cardiac remodeling as assessed by improvements in cardiac structure, function, and coupling with the arterial system remain unclear. We present 2 cases of patients who initially presented with decompensated heart failure, and despite initial medical therapy and continued outpatient follow-up, were unable to tolerate full escalation of guideline-directed medical therapy. The patients remained symptomatic, with high biomarker levels, poor functional capacity, severe heart failure symptoms, and objectively had decreased stroke volume, low left ventricular ejection fraction, and high left ventricular mass.

From Trials to Practice: A 2025 Review of Idecabtagene Vicleucel and Ciltacabtagene Autoleucel Efficacy Across Clinical Studies and Real-World Evidence.

B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapies have revolutionized the approach and management of relapsed/refractory multiple myeloma (RRMM), and as of 2025, idecabtagene vicleucel (ide-cel) and ciltacabtagene autoleucel (cilta-cel) are the only BCMA-targeted CAR T-cell therapies approved by the FDA. Exceptional responses were demonstrated for heavily pretreated patients in the KarMMa-1 trial, reporting a 73% overall response rate (ORR) and 98% in the CARTITUDE-1 trial. Furthermore, both therapies show a significant improvement in progression-free survival (PFS) compared to standard regimens when administered in earlier lines.

The Efficacy and Safety of Teprotumumab in Geriatrics Patients: A Multicenter Study.

Purpose: To evaluate the efficacy and safety of teprotumumab for the treatment of thyroid eye disease in geriatric patients.

Methods: This was a multicenter cohort study of patients aged 75 and older, treated between February 2020 and September 2023 across 10 tertiary institutions. Patients were included if they had moderate-to-severe thyroid eye disease and at least 1 infusion of teprotumumab.

Age and Sex Effects on Cybersickness in Virtual Forklift Training: An Exploratory Study with Practical Mitigation Strategies.

Occupational ApplicationsWe investigated the effects of age and sex on cybersickness susceptibility during Virtual Reality (VR)-based forklift training, using an order picker forklift truck consisting of basic and common forklift driving scenarios. Cybersickness occurrence was assessed using the Simulator Sickness Questionnaire (SSQ) and analyzed with the survival analysis method. Our analysis indicated strong vulnerability among older adults yet no significant influence of biological sex on cybersickness susceptibility.

Water hardness and digestive diseases: a large-scale population-based prospective cohort study.

Background: Water hardness, which refers to the level of dissolved calcium and magnesium salts, is of significant public health concern due to its potential impact on health. The association between water hardness and digestive diseases remains underexplored, with limited evidence from small-scale clinical studies. Given the rising prevalence of digestive disorders worldwide, large-scale cohort studies are needed to address this gap in the literature.

Predicting complex time series with deep echo state networks.

Although many real-world time series are complex, developing methods that can learn from their behavior effectively enough to enable reliable forecasting remains challenging. Recently, several machine-learning approaches have shown promise in addressing this problem. In particular, the echo state network (ESN) architecture, a type of recurrent neural network where neurons are randomly connected and only the read-out layer is trained, has been proposed as suitable for many-step-ahead forecasting tasks.