98%
921
2 minutes
20
Background: The timely transfer of patients with ST-segment elevation myocardial infarction (STEMI) to percutaneous coronary intervention-capable centers is critical for improving outcomes. Although the American Heart Association recommends a door-in-door-out (DIDO) time of ≤30 minutes, national compliance remains low.
Project Rationale: At Harris Health, no patients with STEMI met this benchmark before 2022. We implemented a quality improvement (QI) initiative, including an "Autolaunch" process, to expedite STEMI transfers.
Project Summary: During 2022-2023, we introduced QI initiatives, including the Autolaunch protocol, for patients with unequivocal STEMI. This process included rapid emergency medical services activation, direct catheterization laboratory transfer, and prearrival cardiologist notification. Data were analyzed to assess DIDO times. Before intervention, the median DIDO time was 81 minutes, with 0% of patients meeting the ≤30-minute goal. Postimplementation, the DIDO time decreased to 41 minutes, and compliance reached 39.5%. In Autolaunch cases (n = 35), the median DIDO time was 26 minutes, and the compliance was 74.3%.
Take-home Messages: The STEMI Autolaunch process significantly improved DIDO times. This protocolized approach may serve as a model for optimizing STEMI transfer efficiency and improving patient outcomes.
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http://dx.doi.org/10.1016/j.jaccas.2025.104882 | DOI Listing |
JACC Case Rep
July 2025
Department of Emergency Medicine, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston), Houston, Texas, USA; Texas Emergency Medicine Research Center, Houston, Texas, USA.
Background: The timely transfer of patients with ST-segment elevation myocardial infarction (STEMI) to percutaneous coronary intervention-capable centers is critical for improving outcomes. Although the American Heart Association recommends a door-in-door-out (DIDO) time of ≤30 minutes, national compliance remains low.
Project Rationale: At Harris Health, no patients with STEMI met this benchmark before 2022.
Emerg Med J
June 2025
Guthrie Robert Packer Hospital, Sayre, Pennsylvania, USA.
Background: Thrombectomy is the primary treatment in the management of acute large vessel occlusions (LVO) strokes; however, many rural hospitals are not able to perform this procedure and must transfer patients to thrombectomy-capable centres expeditiously. This quality improvement initiative was aimed at optimising the door-in-door-out (DIDO) time for patients with stroke at a rural primary stroke centre in the USA, with a specific goal of DIDO time of <90 min, 50% of the time and <120 min, 75% of the time.
Methods: System inefficiencies in serial event processing, radiology interpretation, teleneurology application and activation of transferring emergency medical services were identified.
Eur J Neurol
June 2025
Emergency Medical Services, Centre for Prehospital Emergency Care, Wellbeing Services County of Pirkanmaa, Tampere, Finland.
Background: An interfacility transfer should commence immediately to a hospital with endovascular capability to perform mechanical thrombectomy when a patient is diagnosed with a large vessel occlusion (LVO) stroke. The turnaround time in the primary stroke center (PSC) is called door-in-door-out time (DIDO). We investigated DIDOs from two PSCs and how the implementation of a helicopter emergency medical service (HEMS) unit for patient transportation together with a ground ambulance affected the DIDO.
View Article and Find Full Text PDFCan J Neurol Sci
April 2025
Département de neurosciences, Université de Montréal, Montréal, QC, Canada.
Background: The determinants of door-in-door-out metrics (DIDO) at centers referring acute ischemic stroke patients for endovascular thrombectomy (EVT) and the impact of DIDO on functional outcomes are unclear. Our primary objective was to study the association between DIDO and 90-day functional outcomes. Our secondary objective was to investigate the associations between patient clinical and workflow characteristics and DIDO.
View Article and Find Full Text PDFAnn Emerg Med
February 2025
Department of Neurology, University of Chicago, Chicago, IL.
Study Objective: Interhospital transfer is often required in the care of patients with hemorrhagic stroke. Guidelines recommend a door-in-door-out (DIDO) time of ≤120 minutes at the transferring emergency department (ED); however, it is unknown whether DIDO times are related to clinical outcomes of hemorrhagic stroke.
Methods: Retrospective, observational cohort study using US registry data from Get With The Guidelines-Stroke participating hospitals.