Degradation of LiNiMnO Cathodes in the PFSI Ionic Liquid Electrolyte and Carbonate Electrolytes.

LiNiMnO (LNMO) is a promising material for the cathode of lithium-ion batteries (LiBs); however, its high operating voltage causes stability issues when used with carbonate battery electrolytes. Ionic liquids are a viable alternative to conventional carbonate solvents due to their thermal stability and electrochemical window. This work reports the performance of LNMO/Li half cells with an ionic liquid electrolyte (ILE) composed of 0.

The density isobar of water: A comparative study of vdW-DF-cx and RPBE-D3.

Accurately modeling volume-dependent properties of water remains a challenge for density functional theory (DFT), with widely used functionals failing to reproduce key features of the water density isobar, including its shape, density, and temperature of the density maximum. Here, we compare the performance of the RPBE-D3 and vdW-DF-cx functionals using replica exchange molecular dynamics (MD) driven by machine-learned force fields. Our simulations reveal that vdW-DF-cx predicts the water density more accurately than RPBE-D3 and reproduces the isobar closely between 307 and 340 K.

Junior-to-senior transition in elite female football: identifying predominant sources of stress among junior players from both player and coach perspectives.

Introduction: The purpose of this case study is to gain insight into and a deeper understanding of the predominant sources of stress during the junior-to-senior transition experienced by current and former female junior players and their male coaches from both the junior and senior teams.

Methods: All three groups of participants were affiliated with the same Norwegian professional football club. In total, we conducted semistructured interviews with 10 female players: five junior elite players (mean age 16.

Study protocol for 5Ways@School - An implementation and effectiveness trial of a school-based wellbeing intervention in 16 schools in Norway.

Aims: This study aims to assess the effectiveness and implementation of the 5Ways@School curriculum-based intervention in Norwegian schools. The intervention builds on the Five Ways to Wellbeing framework, and promotes five action domains: connect with others, be physically active, take notice, keep learning, and give. The study objectives include assessing the intervention's acceptability, appropriateness, feasibility, fidelity, and cost, as well as its impact on students' wellbeing and mental health.

Engrams Formed in Virtual Reality Exhibit Reduced Familiarity Upon Retrieval: Electrophysiological Correlates of Source Memory Retrieval Indicate Modality-Dependent Differences in Recognition Memory.

Initial findings linking Virtual Reality (VR)-based encoding to increased recollection at retrieval remain inconclusive due to heterogeneous study designs and dependence on behavioral data. To clarify under which circumstances VR-based encoding affects or enhances episodic memory retrieval, the fundamental question remains whether the encoding modality, i.e.

Time to death for on-farm emergency slaughtered cattle in Norway.

Animal welfare and aspects of sustainability are growing concerns in cattle production. In Norway, on-farm emergency slaughter (OFES) accounts for 4.2 % of all cattle slaughter.

Calcium starvation leads to strain-specific gene regulation of lipid and carotenoid production in Mucor Circinelloides.

Fungi are pivotal in transitioning to a bio-based, circular economy due to their ability to transform organic material into valuable products such as organic acids, enzymes, and drugs. Mucor circinelloides is a model organism for studying lipogenesis and is particularly promising for its metabolic capabilities in producing oils like TAGs and carotenoids, influenced by environmental factors such as nutrient availability. Notably, strains VI04473 and FRR5020 have been identified for their potential in producing single-cell oils and carotenoids, respectively.

Carryover effects of feeding tropical fresh or air-dried roughage to Holstein-Friesian crossbred dairy cows on nutritional, techno-functional, and sensory properties of mozzarella cheese.

This study investigated how different dietary roughages, Napier-Pakchong (NP), jumbo sorghum (JB), and rice straw (RS) fed to Holstein-Friesian (HF) crossbred cows affect the nutritional, techno-functional, and sensory properties of mozzarella cheese under tropical conditions in Bangladesh. Iso-nitrogenous (≈12.54% CP) and iso-energetic (ME ≈2.

Charting the equine miRNA landscape: An integrated pipeline and browser for annotating, quantifying, and visualizing expression.

MicroRNAs (miRNAs) are essential regulators of gene expression, yet few comprehensive databases exist for miRNA expression in non-model species, limiting our ability to characterize their roles in gene regulation, development, and disease. Similarly, isomiRs - length and sequence isoforms of canonical miRNAs with potentially altered regulatory targets and functions - have received even less attention in non-model species, including the horse, leaving a critical gap in our understanding of their biological significance. To address these challenges, we developed an open-source, containerized pipeline for identifying and quantifying miRNAs and isomiRs (FARmiR: Framework for Analysis and Refinement of miRNAs), and an associated interactive browser (AIMEE: Animal IsomiR and MiRNA Expression Explorer).

Cell splitting in Staphylococcus aureus is controlled by an adaptor protein facilitating degradation of a peptidoglycan hydrolase.

Regulated protein degradation by Clp proteases is a highly conserved post-translational control mechanism in bacteria. In Staphylococcus aureus, the ClpXP complex targets the peptidoglycan hydrolase Sle1, maintaining a tightly regulated balance between peptidoglycan biosynthesis and hydrolysis, which is required to ensure proper cell splitting without compromising cell integrity. β-lactams antibiotics disturb this balance, leading to their bactericidal effects.

Genome-wide phenotypic insights into mycobacterial virulence using Drosophila melanogaster.

Drosophila melanogaster (Drosophila) is one of the most extensively studied animal models we have, with a broad, advanced, and organized research community. Yet, Drosophila has barely been exploited to understand the underlying mechanisms of mycobacterial infections, which cause some of the deadliest infectious diseases humans are currently battling. Here, we identified mycobacterial genes required for the pathogen's growth during Drosophila infection.

Joint models reveal human subcortical underpinnings of choice and learning behavior.

Decision making and learning processes together enable adaptive strategic behavior. Animal studies demonstrated the importance of subcortical regions in these cognitive processes, but the human subcortical contributions remain poorly characterized. Here, we study choice and learning processes in the human subcortex, using a tailored ultra-high field 7T functional MRI protocol combined with joint models.

Biofeedback therapy using Cerebri for the prevention of migraine attacks in adults with episodic migraine (BioCer): a randomized, wait-list controlled trial - the study protocol.

Introduction: Biofeedback is a non-pharmacological treatment option valued for its minimal risk of adverse events and offers a safe alternative for individuals seeking preventive care for migraine. Despite level A evidence for migraine prevention, biofeedback treatment is still unavailable to most patients. We developed a novel medical device (Cerebri) for multimodal biofeedback treatment that omits the need for healthcare personnel involvement.

Biases in AI: acknowledging and addressing the inevitable ethical issues.

Biases in artificial intelligence (AI) systems pose a range of ethical issues. The myriads of biases in AI systems are briefly reviewed and divided in three main categories: input bias, system bias, and application bias. These biases pose a series of basic ethical challenges: injustice, bad output/outcome, loss of autonomy, transformation of basic concepts and values, and erosion of accountability.

An instrumental variable analysis of body mass index and risk of long-term sick leave: the HUNT Study, Norway.

A more comprehensive understanding of the causal relationships between body mass index (BMI) and sick leave is needed. We aimed to examine the effect of BMI on the risk of cause-specific and all-cause long-term sick leave using an instrumental variable approach. The study included 21,918 adults participating in the two latest surveys of the population-based HUNT Study (HUNT3, 2006-2008 and HUNT4, 2017-2019) linked with registry data on cause-specific sick leave, including musculoskeletal and mental disorders.

Gene expression changes in ducklings exposed in ovo to emerging and legacy per-/poly-fluoroalkyl substances.

This study investigated the effects of two emerging PFAS compounds, perfluorododecane sulfonic acid (PFDoDS) and perfluoro-4-ethylcyclohexane sulfonic acid (PFECHS), alongside legacy perfluorooctanesulfonic acid (PFOS), on gene expression in the liver, heart, and bursa of Fabricius from mallard ducklings (Anas platyrhynchos) exposed in ovo, simulating maternal transfer to the egg. These PFAS compounds were selected based on their detection in a declining sea duck species and concerns over their endocrine disruption potential. Farmed mallard eggs were injected with 80 ng/g of PFDoDS, PFECHS, or PFOS, reflecting concentrations at the upper end of those reported in wild bird eggs.

Education and cardiovascular disease: a within-family Mendelian randomization analysis.

Background: Observational studies have consistently found educational inequalities in cardiovascular disease (CVD) risk. Mendelian randomization (MR) analyses have suggested a direct causal effect of education; however, estimates may be biased by demography or dynastic effects. This study aimed to estimate the effects of educational attainment on CVD risk and serum lipid concentrations before and after accounting for family structure.

Diversity of domestic and imported assemblages of Giardia in Norway and multi-locus sequence typing of domestic assemblage A isolates.

Giardia duodenalis is a gastrointestinal parasite and one of the most frequently reported parasitic infections associated with contaminated water. This study investigated the diversity of domestic and imported Giardia assemblages in Norway, with a focus on the genetic characterization of domestic assemblage A isolates using multi-locus sequence typing (MLST) targeting six genome markers. We analysed 340 human, and 40 animal faecal samples collected between February 2022 and January 2024 from six medical microbiology laboratories and one veterinary diagnostic center across four Norwegian health regions.

Developing, running and evaluating a simulation of a guideline development meeting.

WHAT IS THIS PAPER ABOUT?: Important decisions about healthcare are made in guideline meetings. It is therefore important to involve people who will be affected by the decision. This can include patients, healthcare workers and policy makers.

Plastispheres as reservoirs of antimicrobial resistance: Insights from metagenomic analyses across aquatic environments.

Evidence suggests that plastic particles from various environments can accumulate harmful microorganisms and carry bacteria with antimicrobial resistance genes (ARGs). The so-called "plastisphere" might facilitate the spread of pathogens and antimicrobial resistance across environments, posing risks to human and animal health. This study aimed to analyze the diversity and abundance of ARGs found in plastispheres from various aquatic environments, identify clinically relevant pathogenic species, and ascertain bacterial hosts carrying ARGs.

Severe postpartum haemorrhage at a large referral hospital in Uganda: A prospective observational pilot study.

Background: Postpartum haemorrhage (PPH) is a leading cause of maternal mortality, near-misses and morbidity in Uganda and globally. Kawempe National Referral Hospital (KNRH), Uganda's largest obstetric referral hospital, receives many obstetric emergencies, including PPH, from lower-level health facilities. Little is known about the outcomes and management of severe PPH at KNRH.

Predictors, Healthcare Utilization and Costs Related to Short-Term Stays in Patients with COPD: A Registry-Based Analysis in Norway.

Background: Chronic obstructive pulmonary disease (COPD) incurs significant healthcare costs, often accompanied by multimorbidity. Advanced patients may need short-term stays for rehabilitation, treatment, or respite to maintain home living.

Aim: To identify predictors for a first short-term stay and study the healthcare utilization and costs compared with similar patients without a short-term stay.