1,685,970 results match your criteria: "Japan; Center for Human Development and Family Science[Affiliation]"

Objective: To analyze the hotspots and frontiers in the field of subarachnoid hemorrhage using the bibliometrics method and providing references for academic research.

Methods: All published studies related to subarachnoid hemorrhage published in the Web of Science core database from 1 January 2016 to 25 September 2021 were retrospectively identified using VOSviewer and CiteSpace software. Visualization VOSviewer and CiteSpace software were used to perform statistical and cluster analyses on authors, countries, institutions, keywords, and co-cited documents.

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Hamiltonian Grid-Based QM/MM Method with Mean-Field Embedding for Simulating Arbitrary Slab Geometries.

J Chem Theory Comput

September 2025

Materials DX Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba Central 2, 1-1-1 Umezono, Tsukuba, Ibaraki 305-8568, Japan.

The quantum mechanics/molecular mechanics (QM/MM) method is a powerful approach for investigating solid surfaces in contact with various types of media, since it allows for flexible modeling of complex interfaces while maintaining an all-atom representation. The mean-field QM/MM method is an average reaction field model within the QM/MM framework. The method addresses the challenges associated with the statistical sampling of interfacial atomic configurations of a medium and enables efficient calculation of free energies.

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Catalytic Asymmetric (-)-Carbonyl-Ene Type Cyclizations.

J Am Chem Soc

September 2025

Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany.

The carbonyl-ene reaction between aldehydes and olefins constitutes a perfectly atom economic approach to homoallylic alcohols with concomitant C-C bond formation. However, the scope of catalytic asymmetric intermolecular versions is currently limited to activated substrates, while of the two intramolecular types only catalytic asymmetric (-)-carbonyl-ene type cyclizations can be considered mature. The corresponding (-)-cyclizations would arguably find equal utility in chemical synthesis but remain underdeveloped.

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EVOLVING TRENDS AND EMERGING THEMES IN GUT MICROBIOTA RESEARCH: A COMPREHENSIVE BIBLIOMETRIC ANALYSIS (2015-2024).

Arq Gastroenterol

September 2025

The Japanese Society of Internal Medicine, Editorial Department, Tokyo, Japan.

Background: This study aims to analyze research trends and emerging insights into gut microbiota studies from 2015 to 2024 through bibliometric analysis techniques. By examining bibliographic data from the Web of Science (WoS) Core Collection, it seeks to identify key research topics, evolving themes, and significant shifts in gut microbiota research. The study employs co-occurrence analysis, principal component analysis (PCA), and burst detection analysis to uncover latent patterns and the development trajectory of this rapidly expanding field.

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We investigated the impact of short-term dietary nitrate supplementation on sympathetic neural responses to isometric exercise in postmenopausal women. Ten healthy women aged 64±2 (SD) years participated in this randomized, placebo-controlled, double-blind, crossover study. All participants underwent two-week beetroot juice (BRJ: 800 mg nitrate/day) and placebo (nitrate-depleted BRJ) interventions with ≥14 days of wash-out.

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We present a method for probing the quantum capacitance associated with the Rydberg transition of surface electrons on liquid helium using radio-frequency (rf) reflectometry. Resonant microwave excitation of the Rydberg transition induces a redistribution of image charges on capacitively coupled electrodes, giving rise to a quantum capacitance originating from adiabatic state transitions and the finite curvature of the energy bands. By applying frequency-modulated resonant microwaves to drive the Rydberg transition, we systematically measured a capacitance sensitivity of 0.

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Hopfions-higher-dimensional topological quasiparticles with sophisticated 3D knotted spin textures discovered in condensed matter and photonic systems-show promise in high-density data storage and transfer. Here, we present crystalline structures of hopfions lying in space-time constructed by spatiotemporally structured light. Practical methodologies using bichromatic structured light beams or dipole arrays to assemble 1D and higher dimensional hopfion lattices are proposed, and a technique for tailoring topological orders is elucidated.

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The doped topological insulator Cu_{x}Bi_{2}Se_{3} has attracted considerable attention as a new platform for studying novel properties of spin-triplet and topological superconductivity. In this work, we performed synchrotron x-ray diffraction measurements on Cu_{x}Bi_{2}Se_{3} (0.24≤x≤0.

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Effects of sex and heating rate on skin blood flow oscillations during local heating in young adults.

Am J Physiol Regul Integr Comp Physiol

September 2025

Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, ON, Canada.

to explore sex and heating rate effects on frequency-domain indicators of the mechanisms modulating cutaneous vasodilation during local heating. In thirty young adults (21±3 years, 15 females), wavelet analysis of skin blood flux was assessed from laser-Doppler flux signals at the chest, abdomen, arm, forearm, thigh, and calf during rapid (33-42°C; 1°C·20 s) and gradual (33-42°C; 1°C·5 min) local skin heating. A wavelet transform using a Morlet mother wavelet was computed over the entire signal for each heating protocol (minimum 90 minutes) and 5-min time windows were subsequently isolated to determine responses during baseline and the 42°C heating plateau.

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We report the structural, electrical, and magnetic properties of the organic conductor κ-(BEST)Cu(CN) (BEST: bis(ethylenediseleno)-tetrathiafulvalene; abbreviated as κ-BEST-CN), which is isostructural with the quantum spin liquid candidate κ-(ET)Cu(CN) (ET: bis(ethylenedithio)tetrathiafulvalene; abbreviated as κ-ET-CN). Resistivity measurements demonstrate that κ-BEST-CN exhibits semiconducting behavior, governed by the same conducting mechanism as κ-ET-CN. Under a pressure of ∼0.

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Seafloor geodesy unveils seismogenesis of large subduction earthquakes in Mexico.

Sci Adv

September 2025

Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Mexico City, Mexico.

Based on measurements of near-trench deformations of the oceanic and overriding plates, in this investigation, we elucidate the tectonic and mechanical processes leading to the 7.0 (moment magnitude of 7.0) Acapulco, Mexico, earthquake in 2021.

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The 247-keV state in ^{54}Sc, populated in the β decay of ^{54}Ca, is reported here as a nanosecond isomer with a half-life of 26.0(22) ns. The state is interpreted as the 1^{+} member of the πf_{7/2}⊗νf_{5/2} spin-coupled multiplet, which decays to the 3^{+},πf_{7/2}⊗νp_{1/2} ground state.

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We have performed careful measurements of nonlinear transverse conductivity (NLTC) at zero field in the intermetallic compound HoAgGe with two distinct magnetic toroidal (MT) structures. Below 7 K (MT1 phase), the NLTC signal becomes observable and significantly increases with decreasing temperature, whereas between 7 and 11.6 K (MT2 phase), it remains nearly zero.

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Disorder and non-Hermitian effects together can upend how waves localize. In a 1D disordered chain, the non-Hermitian skin effect (NHSE) can induce Anderson delocalization, defying the usual rule that disorder in low dimensions always localizes states. While weak disorder leaves the NHSE intact, strong disorder restores Anderson localization.

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The unabating discovery of nanoskyrmions in centrosymmetric magnets challenges the conventional Dzyaloshinskii-Moriya (DM) skyrmion stabilization mechanism. We investigate Gd_{2}PdSi_{3} using polarized resonant x-ray scattering and find that the low-field incommensurate modulations are elliptical helices, evolving into spin-density waves at higher fields. Quasi-2D magnetism arises via local DM interactions generated by inversion symmetry breaking around Gd-Gd bonds, which we characterize using atomistic simulations.

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Gaining a fundamental understanding of turbulent flows of dilute polymer solutions has been a challenging and outstanding problem for a long time. In this Letter, we examine homogeneous, isotropic polymeric turbulence at large Reynolds and Deborah numbers through direct numerical simulations. While at the largest scales at which the flow inertial turbulence exists, we find that the flow is fundamentally altered from Newtonian turbulence below the Kolmogorov scale.

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Partonic collectivity is one of the necessary signatures for the formation of quark-gluon plasma in high-energy nuclear collisions. Number of constituent quarks (NCQ) scaling has been observed for hadron elliptic flow v_{2} in top energy nuclear collisions at the Relativistic Heavy Ion Collider and the LHC, and this has been theoretically suggested as strong evidence for partonic collectivity. In this Letter, a systematic analysis of v_{2} of π^{±}, K^{±}, K_{S}^{0}, p, and Λ in Au+Au collisions at sqrt[s_{NN}]=3.

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Femtosecond laser excitation of nanometer thin heterostructures comprising a heavy metal and a magnetically ordered material is known to result in the emission of terahertz radiation. However, the nature of the emitted radiation from heavy metal/antiferromagnet heterostructures has sparked debates and controversies in the literature. Here, we unambiguously separate spin and charge contributions from Pt/NiO heterostructures by introducing an unprecedented methodology combining high external magnetic fields with a symmetry analysis of the emitted terahertz polarization.

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Evaluation of Factors Affecting Depth of Invasion Measurement in Tongue Squmous Cell Carcinoma Using Intraoral Ultrasonography.

Dentomaxillofac Radiol

September 2025

Division of Oral and Maxillofacial Radiology, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, 2-5274 Gakkocho-dori, Chuo-ku, Niigata, 951-8514, Japan.

Objective: Intraoral ultrasonography (US) is known for its high accuracy in evaluating the depth of invasion (DOI) in tongue squamous cell carcinoma (SCC). However, measurement discrepancies, such as overestimation or underestimation, can occur in certain cases. This study aimed to identify factors affecting the measurement accuracy of intraoral US.

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The Tone River in Japan represents one of the southern limit distributions of chum salmon (Oncorhynchus keta) on the western side of the North Pacific, but the number of adult chum salmon observed here has declined dramatically since 2013 and reached zero in 2024. The factors behind the recent decline of the chum salmon population in the Tone River were investigated by using ocean reanalysis data and a 20-year particle-tracking simulation. Virtual chum salmon fry were released at the mouth of the Tone River in spring each year with six different swimming strategies to evaluate the effects of ocean currents on the population growth rate of salmon.

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Data-Driven Exploration of Critical Factors for Single-Phase High-Entropy Oxide Anode Materials.

J Phys Chem Lett

September 2025

Institute of multidisciplinary research for advanced materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan.

High-entropy oxides (HEOs) are attracting significant attention owing to their compositional tunability and structural robustness. However, the identification of specific compositional combinations that yield a single-phase structure in HEOs remains unclear owing to the immense combinatorial complexity inherent in multielement systems. This study adopts a materials informatics approach that integrates experimental synthesis data with machine learning to identify key compositional factors enabling single-phase HEO formation via solid-state synthesis.

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Microglia, the resident macrophages in the central nervous system (CNS), have been intensively studied using rodent genetic models, including the Cre-loxP system. Among them are tamoxifen (TAM)-inducible CX3C chemokine receptor 1 (Cx3cr1)-Cre mouse lines (Cx3cr1), which have enabled in-depth analyses of the biological features and functions of myeloid cells, including microglia. Occasionally, these Cx3cr1 tools have yielded conflicting biological outcomes, the underlying mechanism of which remains unclear.

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This study aimed to identify brain activity modulations associated with different types of visual tracking using advanced functional magnetic resonance imaging techniques developed by the Human Connectome Project (HCP) consortium. Magnetic resonance imaging data were collected from 27 healthy volunteers using a 3-T scanner. During a single run, participants either fixated on a stationary visual target (fixation block) or tracked a smoothly moving or jumping target (smooth or saccadic tracking blocks), alternating across blocks.

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Influence of Cooking Methods on Phenolic Compounds and their Activities in Pea Shoots (Pisum sativum).

Plant Foods Hum Nutr

September 2025

Graduate School of Food and Nutritional Sciences, Toyo University, 48-1, Oka, 351-8501, Asaka, Saitama, Japan.

Pea shoots (Pisum sativum) are well known to have nutritional benefits when consumed raw; however, the effects of home cooking on their bioactive compounds remain unclear. Therefore, we investigated how different cooking methods affect the antioxidant activity and stability of antioxidants. Our evaluation revealed that antioxidant activity is preserved by steaming but significantly reduced by microwaving and boiling, which also causes weight loss during cooking.

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