One-year mortality rates of fragility fractures of the pelvis: a systematic review and meta-analysis.

Purpose: This study investigates the 1-year mortality of fragility fractures of the pelvis (FFP) in patients categorized under this system and treated with surgery or conservative methods, aiming to assess the algorithm's effectiveness.

Methods: We systematically searched PubMed, Embase, Scopus, and Web of Science for English studies on the 1-year mortality of FFP, with no publication date restrictions. Study quality was assessed using the Newcastle-Ottawa Scale.

Association of single-nucleotide polymorphism with spirometry indices and pulmonary ventilation characteristics in patients with chronic obstructive pulmonary disease.

ObjectivesGenome-wide association studies have identified as a gene linked to chronic obstructive pulmonary disease. Several single-nucleotide polymorphisms-notably, rs7671167, rs2869967, rs2869966, and rs17014601-are associated with chronic obstructive pulmonary disease susceptibility and spirometric indices. This study aimed to investigate the association between single-nucleotide polymorphisms and spirometric indices in chronic obstructive pulmonary disease and non-chronic obstructive pulmonary disease patients and assess the correlation of these single-nucleotide polymorphisms with pulmonary ventilation function.

Enhancing quality of life and functional capacity in heart failure patients with iron deficiency: A regional cross-sectional study on intravenous iron therapy in Vietnam.

Intravenous iron supplementation, particularly ferric carboxymaltose (FCM), has emerged as an effective therapeutic strategy for correcting iron deficiency (ID) in patients with heart failure with reduced ejection fraction (HFrEF). However, the enhancement related to the quality of life (QoL) and functional capacity remains unclear, specifically in the Vietnam population. This study assesses the enhancement of QoL and functional capacity in intravenous FCM therapy in heart failure patients with ID.

A case series on the outcomes of laparoscopic pull-through surgery combined with Swenson-like technique and intraoperative frozen section biopsy for Hirschsprung's disease in children.

The combination of laparoscopic pull-through surgery with intraoperative frozen section biopsy has emerged as a promising approach in the treatment of Hirschsprung's disease. This case-series report study aims to describe the short-term outcomes. All patients who underwent one-stage laparoscopic pull-through surgery combined with the Swenson-like technique at the General Surgery Department of Children's Hospital No.

Prevalence and distribution of human papillomavirus in genital warts in Can Tho City, Vietnam: a cross-sectional study.

Background: Human papillomavirus (HPV) is the major causative agent of genital warts and various anogenital cancers. In Vietnam, limited data exists on HPV genotype prevalence and distribution. This study aimed to determine the prevalence and distribution of HPV types among patients with genital warts in Can Tho City and to explore their associations with demographic and clinical characteristics.

Comparing the Effectiveness of 0.12% Chlorhexidine and Silver Nanoparticles Mouthwashes: A Double-Blind Randomized Controlled Trial Among Medical Students in Southern Vietnam.

Background: Dental plaque and gingivitis are prevalent conditions that can be controlled using antimicrobial mouthwashes.

Aim And Design: This double-blind, randomized controlled clinical trial aims to compare the effectiveness of 0.12% chlorhexidine (CHX) and silver nanoparticles (AgNPs) mouthwashes in managing dental plaque, gingivitis, microbial counts, and saliva pH.

Isolation of phytochemicals and exploration the mechanism of Dolichandrone spathacea in the treatment of chronic bronchitis by integrating network pharmacology, molecular docking, and experimental validation.

Background: Dolichandrone spathacea (D. spathacea) is a traditional medicine used to treat chronic bronchitis (CB) in Vietnam and India. However, phytochemicals and potential mechanisms of this species against CB have not been fully illuminated.

AI-Driven Deep Learning Approach for Pan-Cancer Immune Profiling.

The tumor immune microenvironment (TME) influences cancer progression and treatment. RNA-Seq has identified six immune subtypes: Wound Healing (WH, C1), IFN- Dominant (IFNG, C2), Inflammatory (INF, C3), Lymphocyte Depleted (LD, C4), Immunologically Quiet (IQ, C5), and TGF-β Dominant (TGFb, C6). This study uses a Convolutional Neural Network (CNN) to classify these subtypes from RNA-Seq data.

Lipid Profile and Apolipoprotein B Serum Levels in the Vietnamese Population With Newly Diagnosed Elevated Low-Density Lipoprotein Cholesterol and Association With the Single-Nucleotide Variant rs676210: Cross-Sectional Study.

Background: Apolipoprotein B (APOB) rs676210 polymorphism has been associated with altered lipid metabolism and cardiovascular risk in various populations; however, data from Vietnamese populations remain limited.

Objective: This study aimed to investigate the association of the APOB rs676210 variant with lipid profiles among Vietnamese individuals newly diagnosed with elevated low-density lipoprotein cholesterol (LDL-C).

Methods: A cross-sectional study was conducted among 69 Vietnamese adults newly diagnosed with elevated LDL-C (≥130 mg/dL) at a tertiary hospital in Southern Vietnam.

Minimally invasive surgery for bilateral large basal ganglia hemorrhage: a rare case report and insights from literature.

Background: Acute bilateral basal ganglia hemorrhage is a rare and life-threatening condition, often associated with high morbidity and mortality. Timely diagnosis and intervention are crucial to improving outcomes. This report presents a case successfully managed with minimally invasive surgery (MIS).

Detection of the Sulfamethoxazole Antibiotic by Gold Nanoparticles: Binding Mechanism and SERS Spectra.

Quantum chemical calculations using density functional theory are performed to evaluate the adsorption behavior and characteristics of surface-enhanced Raman spectroscopy (SERS) of sulfamethoxazole (SMZ), a powerful antibiotic, on gold nanoparticles. The gold nanostars are experimentally prepared and characterized by SEM and TEM techniques and X-ray and UV spectroscopies. Small gold clusters Au with = 6 and 20 are used to mimic the gold nanostructured surfaces.

Immediate Implant Placement in the Esthetic Zone with Marginal Preservation: Esthetic Outcomes in Sites with Thin Buccal Bone Wall.

Purpose: To assess facial soft tissue levels and buccal bone thickness following immediate implant placement in compromised maxillary anterior sockets using marginal preservation technique.

Materials And Methods: A total of 49 patients with failing maxillary anterior teeth were assigned to single immediate implant placement using appropriately sized implants, combined with absorbable collagen matrix membrane and sticky demineralized freeze-dried bone allograft grafting. Definitive crown placement occurred 6 months after provisionalization.

Effects of cetylated fatty acids on knee osteoarthritis: a systematic review and meta-analysis of real-world evidence.

Objectives: Knee osteoarthritis (OA) continues to be a debilitating global health issue, with effective treatments that have minimal side effects still lacking in modern clinical practice. Cetylated fatty acids (CFAs), a group of esterified fatty acids administered either topically or orally to protect the synovial membrane and stabilise cell membranes, appears to be a promising therapeutic option.

Methods: We conducted a comprehensive search in PubMed, Embase, Cochrane Library, CENTRAL, and Web of Science from the inception until November 2024 to examine the therapeutic effects of CFAs.

Red cell distribution width as an inflammatory biomarker for predicting one-year survival after geriatric hip fracture: A prospective cohort study.

Introduction: Geriatric hip fractures are a significant public health concern due to their high morbidity and mortality rates, especially within the first year post-injury. Identifying predictors of mortality can guide early risk assessment and improve outcomes. We aimed to determine the one-year mortality rate following hip fractures and identify clinical and laboratory features associated with the mortality.

Chemsex: Emerging Threats Facing the MSM Experience - A Cross-Sectional Study.

Background: The trend of male homosexuality is progressively rising. The preference for chemsex (use of recreational drugs during sexual encounters) is also becoming more prevalent among the men who have sex with men (MSM), which increases sexual excitement during intercourse. This, in turn, heightens the risk of transmission of sexually transmitted diseases, including HIV/AIDS.

Mobile-bearing versus Medial-pivot Designs in Total Knee Arthroplasty: A Meta-analysis.

Background: Mobile-bearing (MB) and medial-pivot (MP) prostheses are the two popular designs used in total knee arthroplasty (TKA), yet their long-term outcomes remain controversial. This meta-analysis was conducted to determine whether there are any differences in outcomes between patients who receive these two prostheses in TKA.

Method: We comprehensively searched electronic databases up to November 2024.

Evaluating the efficacy of vascularized pedicled skin flaps in treating sacrococcygeal pressure ulcers.

Background: Pressure ulcers, particularly sacrococcygeal ulcers, represent a persistent healthcare challenge despite being preventable. This study aims to evaluate the outcomes of using vascularized pedicled skin flaps for sacrococcygeal pressure ulcer treatment and to identify factors influencing these outcomes at our hospital.

Methods: A descriptive case series study was conducted on 42 patients with sacrococcygeal pressure ulcers treated using pedicled skin flaps with preserved vascular supply from May 2018 to May 2023.

Environmental Press in Older Adults From the Perspective of Gerontological Nursing: A Concept Analysis.

Background: As adults age, most aspects of their living environment, physical and mental health, personal relationships and perspectives on life change. The ability of older adults to adapt to this myriad of physical and social changes, known as environmental press, is important for maintaining autonomy and well-being as they age. Understanding the concept of environmental press for older adults could improve person-centred care provided by gerontological nurses.

The effect of antimicrobial stewardship interventions upon antimicrobial consumption and appropriateness in Vietnamese district hospitals: a cluster randomised trial.

Background: Inappropriate antimicrobial use is a key driver of antimicrobial resistance. Antimicrobial stewardship (AMS) promotes the judicious use of antimicrobials to address this problem. This study evaluated the effect of an AMS program on antimicrobial prescribing practices in district hospitals in Vietnam.

Burden and risk factors of Alzheimer's disease and other dementias in Vietnam from 1990 to 2021 - A comprehensive analysis from global burden disease.

Background: Alzheimer's disease (AD) is the primary cause of dementia worldwide, imposing a substantial health and economic burden. In Vietnam, an aging population and rapid socioeconomic changes have intensified concerns about AD and other dementias burden.

Methods: We analyzed data from the Global Burden of Disease (GBD) 2021 database to estimate age-standardized rates (ASRs) of incidence, prevalence, mortality, years lived with disability (YLDs), and years of life lost (YLLs) for AD in Vietnam from 1990 to 2021.

Burden and risk factors of cervical cancer in Vietnam from 1990 to 2021 and forecasting to 2050-a systematic analysis from global burden disease.

Background: Cervical cancer continues to be a significant global health challenge, with Vietnam facing similar concerns. Although there has been some progress in lowering its incidence and mortality rates, a comprehensive understanding of long-term trends and the factors driving these changes remains limited.

Objective: This study aimed to analyze the burden and risk factors of cervical cancer in Vietnam over a 3-decade period, from 1990 to 2021 with projection to 2050.

HIV Infection Among Pregnant Women in a Vietnamese Population: Prevalence and Associated Factors.

Background: In pregnant women, HIV infection warrants special attention due to the high risk of complications during pregnancy and the increased likelihood of fetal HIV exposure. Consequently, screening for HIV in pregnant women within the community and identifying associated risk factors are essential.

Objective: The study aims to investigate the prevalence of HIV infection and the associated risk factors in pregnant women.