Purpose: This study investigates the 1-year mortality of fragility fractures of the pelvis (FFP) in patients categorized under this system and treated with surgery or conservative methods, aiming to assess the algorithm's effectiveness.
Methods: We systematically searched PubMed, Embase, Scopus, and Web of Science for English studies on the 1-year mortality of FFP, with no publication date restrictions. Study quality was assessed using the Newcastle-Ottawa Scale.
Objectives: Fractures located at the inferior pole of the patella pose challenges in terms of fracture fixation, primarily due to inadequate bone quality at the lower pole and typically limited options for secure fixation. This study introduces a novel approach that involves employing the Krackow suture technique on the patellar tendon, followed by a longitudinal transosseous and upside-down fixation at the superior aspect of the patella using a suture anchor to address this challenge.
Methods: A retrospective cohort case series was conducted at a single center, involving ten patients with fractures at the lower pole of the patella.
Introduction: Geriatric hip fractures are a significant public health concern due to their high morbidity and mortality rates, especially within the first year post-injury. Identifying predictors of mortality can guide early risk assessment and improve outcomes. We aimed to determine the one-year mortality rate following hip fractures and identify clinical and laboratory features associated with the mortality.
View Article and Find Full Text PDFTotal knee arthroplasty (TKA) is a treatment for knee pain, but some patients are not satisfied with their outcomes. Utilizing shared decision making (SDM) can lead to better decisions, satisfaction, and fewer regrets. However, healthcare professionals have little knowledge of risk factors for regret.
View Article and Find Full Text PDFBackground: The increasing prevalence of diabetes mellitus and obesity poses growing challenges for total joint arthroplasty, as both conditions are associated with higher risks of periprosthetic joint infection (PJI), delayed wound healing, and prolonged hospitalization. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown benefits in glycemic control, weight reduction, and inflammation modulation, making them a potential perioperative intervention. However, their protective effects on postoperative outcomes in arthroplasty remain uncertain, necessitating further investigation.
View Article and Find Full Text PDFObjective: Glaucoma is a leading cause of irreversible blindness worldwide, with incidence expected to increase with the aging global population. In this study, we aimed to investigate the association between long-term exposure to ambient air pollution and the risk of primary open- angle glaucoma (POAG).
Design: Retrospective, nationwide, population-based cohort study.
Osteoarthritis Cartilage
May 2025
Objective: To investigate the association between long-term exposure to ambient air pollution and the risk of developing osteoarthritis (OA) in a large nationwide cohort in Taiwan.
Design: We conducted a retrospective cohort study using data from Taiwan's National Health Insurance Research Database linked with air pollution monitoring records from 76 environmental stations between 1993 and 2013. A total of 526,630 adults with complete 10-year cumulative exposure data were followed from the end of the exposure window until OA diagnosis, death, or study end.
Ophthalmic Plast Reconstr Surg
May 2025
Purpose: Thyroid eye disease (TED) is a significant orbital disorder commonly associated with Graves' disease, characterized by retrobulbar tissue enlargement and various ocular symptoms. While the pathophysiology involves autoimmune processes, the potential influence of air pollution on TED remains unexplored. This study aims to investigate the association between long-term air pollution exposure and the risk of TED in Taiwanese adults with thyroid disease.
View Article and Find Full Text PDFBackground: With an aging population, the prevalence of lumbar spinal diseases necessitating surgical intervention is increasing. Handgrip strength (HGS) has emerged as a simple measure of muscle function that may correlate with surgical outcomes. However, the role of HGS concerning postoperative recovery following transforaminal lumbar interbody fusion (TLIF) is not well-studied, highlighting a gap in the literature regarding its potential as a prognostic tool.
View Article and Find Full Text PDFBackground: Hand osteoarthritis (HOA) is a prevalent degenerative joint disease, with emerging evidence suggesting metabolic factors, including dyslipidemia, play a role in its pathogenesis. Dyslipidemia components, including low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides, may contribute to cartilage damage and inflammation in hand joints, though robust evidence is limited.
Method: A systematic review and meta-analysis were conducted using PubMed, Embase, and Web of Science to identify case-control and cohort studies examining the association between dyslipidemia and HOA.
Vertebral augmentation is a safe and effective treatment for osteoporotic vertebral compression fractures (OVCFs) in elderly patients. The impact of sarcopenia on post-procedure outcomes has been debated. This meta-analysis examined its effect on outcomes following vertebral augmentation in OVCF patients.
View Article and Find Full Text PDF: The incidence of hip fractures is increasing, and there have been reports linking cold weather to a higher risk of fractures. This study aimed to evaluate clinical variables in hip fracture patients who may predispose them to such fractures under different temperatures. : This is a cross-sectional study conducted at a single medical center, enrolling older adults (≥60 years) who had experienced a hip fracture.
View Article and Find Full Text PDFIntracerebral hemorrhage (ICH) represents the most severe subtype of stroke, and the lack of effective clinical pharmacotherapies poses a substantial threat to human health. Hematoma plays a crucial role in determining the prognosis of ICH patients by causing primary mechanical extrusion, followed by secondary brain injuries, such as cerebral edema, iron-mediated oxidative stress, and inflammation resulting from its degradation products. 5α-androst-3β,5α,6β-triol (TRIOL) is a neuroprotective steroid currently undergoing phase II clinical trial for acute ischemic stroke with anti-oxidative and anti-inflammatory properties.
View Article and Find Full Text PDFAims: We conducted this study to investigate the impact of muscle loss on musculoskeletal health, fall and fracture risks, and activities of daily living (ADL) in elderly patients with osteoporosis.
Materials And Methods: This age- and sex-matched cross-sectional study analyzed data from a medical center involving patients aged ≥ 50 from 2020 to 2022. The included participants were formed into three groups: 100 with osteoporosis only, 100 with osteosarcopenia, and 50 control individuals without osteoporosis and sarcopenia.
Background: Septic arthritis is a rare but devastating complication after anterior cruciate ligament reconstruction (ACLR). While early treatment can prevent significant graft complications, outcomes are often inferior to those in uncomplicated ACLR. Furthermore, whether to retain or remove the graft after infection remains debatable.
View Article and Find Full Text PDFPurpose: Periprosthetic joint infection (PJI) is a serious complication after joint arthroplasty, resulting in high morbidity and mortality. The neutrophil-to-lymphocyte ratio (NLR) and albumin-to-globulin ratio (AGR) are novel diagnostic markers for PJI; however, their diagnostic value remains inconsistent.
Methods: This meta-analysis was conducted using the PubMed, Embase, and MEDLINE databases to determine the diagnostic accuracy of NLR and AGR for PJI in the knee or hip.
Geriatr Orthop Surg Rehabil
October 2024
Introduction: Hip fracture is particularly seen in elderly patients with frailty and osteoporosis and leads to diminished functional independence and quality of life. Despite the susceptibility of these patients to a second hip fracture (SHF), the literature insufficiently discussed its impact leading to poor outcomes. This study aims to directly assess the outcomes of elderly patients with initial hip fractures (IHF) vs those experiencing an SHF within a well-matched group with similar characteristics.
View Article and Find Full Text PDFPurpose: Studies have reported conflicting findings on the relationship between smoking and surgical site infection (SSI) post fixation for ankle and calcaneal fractures. This meta-analysis explored the effect of smoking on SSI incidence following open reduction and internal fixation (ORIF) of these fractures.
Methods: Full-text studies on smoking's influence on post-ORIF SSI rates for closed ankle and calcaneal fractures were sourced from the PubMed, Embase, and Cochrane databases, with no consideration given to language or publication date.
Background: Smoking has long been recognized as a risk factor for impaired wound and bone healing, particularly in the context of ankle and foot surgery. Despite numerous studies exploring the association between smoking and complications following ankle replacement, there remains significant inconsistency in their findings. Therefore, this meta-analysis study aims to elucidate whether smoking increases the rate of complications after total ankle arthroplasty (TAA), providing valuable insights for clinical management.
View Article and Find Full Text PDFPsoriasis is an immune-mediated disorder which primarily affects skin and has systemic inflammatory involvement. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII), and monocyte-to-lymphocyte ratio (MLR) are novel complete blood count (CBC)-derived markers which can reflect systemic inflammation. This study aimed to systematically investigate the associations of NLR, PLR, SII, and MLR with psoriasis.
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