Correction: Therapeutic target analysis and molecular mechanism of melatonin-treated leptin resistance induced obesity: a systematic study of network pharmacology.

[This corrects the article DOI: 10.3389/fendo.2022.

Solvent-driven spectroscopic and quantum chemical evaluation of 2-[(trimethylsilyl) ethynyl]thiophene with molecular docking insights.

Thiophene derivatives are recognised for their notable biological and pharmacological properties. This study examines the electronic structure and antibacterial properties of 2-[(Trimethylsilyl)ethynyl]thiophene (2TSET), emphasising the effects of solvent environments. We utilised spectroscopic techniques such as Fourier transform infrared (FT-IR), ultraviolet-visible (UV-Vis), and Raman spectroscopy (FT-Raman) to verify the molecular geometry of 2TSET.

Enhancement of optical limiting activity of para-aminobenzoic acid using silver nanoparticles.

An extensive study on the laser power limiting behavior of para-aminobenzoic acid (PABA) combined with silver nanoparticles (PABA + AgNPs) was done and reported in this article. The XRD spectra for PABA + AgNPs confirm its crystalline structure. The absorption spectra of AgNPs and PABA + AgNPs indicate complete stability of the samples.

Experimental exploration of QbD employed bio-inspired chitosan/zinc oxide nanocomposites for water remediation.

Chitosan (CS), a naturally occurring biopolymer obtained from chitin, has garnered considerable interest in environmental remediation owing to its distinctive attributes. Its inherent biodegradability and exceptional antimicrobial, photocatalysis, and ultraviolet protective characteristics render it a promising polymer for advancing sustainable applications. This study presents the eco-synthesis of Zinc oxide nanoparticles (ZnONPs) from Moringa oleifera (MO) and the development of chitosan-conjugated nanocomposites (MO-CS/ZnONCs) for environmental bioremediation.

Synthesis, Absorption and Emission Behaviour, Solvation, AIM, Topology, and Docking Studies on 4-(((perfluorophenyl) methylene)amino)-N-(thiazol-2-yl) Benzene Sulfonamide.

This work aims to synthesize 4-(((perfluorophenyl) methylene)amino)-N-(thiazol-2-yl) benzene sulfonamide (PFTH) and characterize it using various instrumental techniques such as UV-visible (UV-vis), fluorescence, Fourier-transform-infrared (FTIR), Raman, and nuclear magnetic resonance (NMR) spectroscopy analyses, respectively. The density functional theory (DFT) calculations have been performed using correlation-consistent polarized valence double-zeta (cc-pVDZ) basis sets and Becke, 3-parameter Lee-Yang-Parr (B3LYP) functionals, respectively. In this study, we used Gauge-Including Atomic Orbitals (GIAO) to determine the computational techniques for nuclear magnetic resonance (C NMR and H NMR) spectroscopy.

Synthesis of Vanillin derivative Schiff's bases from threonine, and valine: Structural study and multiscale computational modeling.

Addressing the escalating global challenge of antimicrobial resistance, this study reports the synthesis, comprehensive structural characterization, and multiscale computational modeling of two novel vanillin-derived Schiff's bases, 1 (from threonine) and 2 (from valine). Spectral analyses confirmed their successful formation. Antimicrobial assays revealed significant activity against a panel of Gram-negative (Escherichia coli, Pseudomonas aeruginosa), Gram-positive (Bacillus subtilis, Staphylococcus aureus), and fungal (Candida albicans, Aspergillus flaves) strains.

Propagation of extreme events in multiplex neuronal networks.

In previous studies, the propagation of extreme events across nodes in monolayer networks was studied extensively. In this work, we extend this investigation to explore the propagation of extreme events between two distinct layers in a multiplex network. We consider a two-layer network, where one layer is globally coupled and exhibits extreme events, while the second layer remains uncoupled.

Spin-torque nano-oscillators for reservoir computing applied to time-series data.

Recent investigations have discovered the potential of high-dimensional nonlinear systems for predicting nontemporal and temporal tasks. The prediction is demonstrated here for an asymmetrical seventh-degree polynomial and time series of variables in Rössler system by using spin-torque nano oscillator (STNO) as a reservoir corresponding to the nontemporal and temporal tasks, respectively. For training, the inputs are supplied through the bifurcation parameters, (i) magnitude of the alternating current (AC) passed through the STNO and (ii) the frequency with which the AC is applied.

Realization of multiple-input and single-output logic gates in nonlinear systems.

We investigate the designing of multiple-input and single-output (MISO) logic gates using a periodically driven double-well Duffing oscillator system. Our research focuses on the existence of OR and AND logic gate properties in the output of a single double-well Duffing oscillator with multiple inputs under the influence of external periodic forcing and bias. Through our investigation, we demonstrate that the logic gate can be switched between OR and AND by adjusting the bias value.

Self-feedback delay induces extreme events in the theoretical Brusselator system.

We present a study of the theoretical Brusselator model with time-delayed self-feedback, demonstrating its ability to induce extreme events when delays in reaction processes significantly influence subsequent dynamics, with and without diffusion. Stability analyses reveal the mechanisms driving this behavior with respect to the delay time. The occurrence of extreme events is validated using various numerical and statistical tools, including phase portraits, time series, probability distribution functions, return periods, and spatiotemporal evolution.

Prevalence of paediatric diarrhoea in Arba minch government health institutions, Southern Ethiopia and associated factors.

Infectious diarrhoea is one of the leading causes of paediatric morbidity and mortality in developing countries like Ethiopia; several factors contribute to the worsening of condition. This study was aimed to determine the prevalence and associated factors of enteropathogens, and antimicrobial susceptibility patterns of enterobacteria among paediatric patients attending four selected government health institutions in Arba Minch, southern Ethiopia. The study materials were stool samples collected from 367 paediatric patients with acute diarrhoea, which were then inoculated onto MacConkey agar, xylose lysine deoxycholate agar, and Campylobacter selective media for the isolation of enteric bacteria.

Studies on the pharmacological potential of starfish using acute oral toxicity, anti-nociceptive, locomotor, and cytotoxic activities.

In the present study, starfish () specimens were collected from bycatch trash fish at a fish landing center, and their pharmacological and cytotoxic potentials were evaluated through acute oral toxicity, anti-nociceptive and locomotor assays, as well as cytotoxicity assay. The crude ethanol extract from starfish was purified by liquid-liquid partition chromatography using cyclohexane and n-butanol was used to determine the acute oral toxicity (LD) and a histopathological examination of the rat. In acute oral toxicity studies, an LD value of 33.

Green synthesis of copper hydroxide nanorods using leaf extracts: a promising approach for antimicrobial, antioxidant, and anticancer applications.

Unlabelled: Copper hydroxide nanorods (Cu(OH)₂ NRs) were successfully produced using ethanolic leaf extracts of utilizing a green synthesis technique. UV-Vis, FTIR, XRD, and SEM-EDX analysis revealed the development of orthorhombic, rod-shaped nanoparticles with an average size of ~ 50 nm. Cu(OH)₂ NRs showed significant antibacterial activity, with inhibition zones ranging from 8.

Impact of Hydrothermal Treatment on the Bioactive Compounds of Different Brown Rice Varieties in India.

Hydrothermal processing is known to influence the nutritional and functional properties of cereals; however, its effects on the bioactive metabolite composition of traditional Indian brown rice varieties remain underexplored. In this study, we investigated the impact of hydrothermal treatment on four indigenous rice varieties, Seeraga samba, Kattu ponni, Kuzhiyadichaan, and Poongar, focusing on the compositional changes in lipophilic bioactive compounds. Using GC-MS/MS analysis, we quantified the alterations in fatty acids, phytosterols, triterpenes, and tocopherols before and after processing.

Comparative chloroplast genomics of wild-type Panicum miliaceum cv. ATL1 and its M mutant line: insights for molecular breeding applications.

Background: Proso millet (Panicum miliaceum L.), one of the oldest domesticated crop, remains an underexploited resource with significant potential for nutrition and yield. With evolving breeding perspectives, genomic knowledge is increasingly vital for developing new crop varieties.

Protective effect of hydroalcoholic Crateva religiosa G. Forst. bark extract on oxidative stress, hormonal imbalance and gene expressions (CYP19A1 and PPARγ) in letrozole-induced polycystic ovarian syndrome rats.

Ethnopharmacological Relevance: The bark of Crateva religiosa has been traditionally used in Ayurveda for its anti-inflammatory, cytotoxic, and antiproliferative properties, particularly in treating cysts and inflammation, making it a potential agent in managing Polycystic Ovarian Syndrome (PCOS).

Aim: The present study aims to evaluate the effects of hydroalcoholic C. religiosa bark extract (CRE) on letrozole-induced PCOS rats.

Ecological features of zooplankton (copepods) in the perennial oceanic oxygen minimum zone in the Eastern Arabian Sea.

Copepods are the most abundant metazoan/mesozooplankton in the ocean and are adapted to survive in diverse environmental conditions. Exclusive studies on copepods in the Eastern Arabian Sea (EAS) with emphasis on their composition and ecophysiological characteristics, especially from the perennial oceanic Oxygen Minimum Zone (OMZ), are almost absent. Therefore, this work presents the results of a stratum-wise vertical sampling of mesozooplankton over the mixed layer, thermocline, and OMZ along the Indian west coast in the EAS using a Multiple Plankton Net during the Northeast Monsoon (NEM) and Southwest Monsoon (SWM).

Surface engineering of nano magnesium alloys for orthopedic implants: a systematic review of strategies to mitigate corrosion and promote bone regeneration.

Magnesium (Mg) alloys are transformative candidates for biodegradable orthopedic implants due to their bone-mimetic elastic modulus (10-30 GPa), biocompatibility, and osteogenic properties. However, rapid corrosion (>2 mm/year) and hydrogen gas evolution (0.1-0.

Lumefantrine-doped cerium oxide nanoparticles: investigating their antibacterial and mosquito larvicidal properties.

Silver-doped cerium oxide nanoparticles (Ag-doped CeO₂ NPs) were synthesized using lumefantrine as a capping agent and characterized using UV-Vis, TEM, SEM, EDX, XRD, FTIR, and zeta potential analyses. The nanoparticles exhibited strong larvicidal activity against , with LC₅₀ values of 10.432 µg/mL (third instar) and 12.

Arboviruses and COVID-19: Global Health Challenges and Human Enhancement Technologies.

Currently, there is increasing concern about severe illnesses, particularly those caused by viruses such as SARS-CoV-2 and arboviruses [...

Phyco-Fabricated Zinc Oxide Nanorods From Dictyota dichotoma Seaweed: A Promising Resource for Environmental and Biomedical Applications.

Nanorods (NRs) have extensive applicability across all scientific disciplines due to their distinctive size, varied shape, and elevated surface-to-volume ratio, which confer distinctive advantages. Nanorod substances are capable of solving nearly any difficulty in sciences. The advancement of nanotechnologies has led to the emergence of metallic or metal oxide nanoparticles as potentially exciting resources.

BiAgOTe nanosheets with enhanced photoresponse ability: an experimental and computational study.

Oxychalcogenides containing metals have fascinating physical and chemical properties, making them well-suited for electronic and optoelectronic applications. In the present report, bismuth silver oxytelluride (BiAgOTe) samples synthesized by a microwave (MW) method were characterised for photodetector applications. The synthesized samples exhibited a polycrystalline structure through X-ray diffraction.

Multi-locus genome-wide association studies reveal genomic regions associated with sodicity tolerance in rice.

Rice is a major food crop and serves as the primary food source for over half of the world's population, particularly in Asia. However, its cultivation is constrained by several abiotic stresses, notably sodicity, which significantly reduces productivity and is expected to worsen in the near future. In this study, a genome-wide association study (GWAS) was conducted to identify genomic regions and candidate genes associated with sodicity tolerance in rice.

Upcycling agro-waste as a physical template for synthesizing self-doped FeO and CuO nanoparticles: Assessing textile dye and antibiotics degradation efficiency.

Instituting an environmentally sustainable and industrially viable method for generating photocatalytic nanoparticles (NPs) through green synthesis is highly challenging due to the complexity of the current protocols. The present study thus investigated the utility of banana flower perianth, a non-edible agro-waste with self-assembled microporous architecture, as a physical template to synthesize FeO and CuO NPs through one-pot synthesis. The synthesized NPs were spherical and highly crystalline.