952,504 results match your criteria: "Australia; Perron Institute for Neurological and Translational Science[Affiliation]"

Addressing underrepresented homicide and climate data in forensic science: The case for new human taphonomy facilities in tropical regions.

Sci Justice

September 2025

School of Chemistry, University of Leicester, University Road, Leicester LE1 7RH, United Kingdom; Coventry University, School of Science, Coventry CV1 2DS, United Kingdom.

This review explores the geographical distribution of human taphonomy facilities (HTFs) in connection to climate and homicide rates from the 50 most impacted cities worldwide. Existing HTFs depict temperate climates, omitting tropical and arid areas. This underrepresentation impairs accurate post-mortem interval (PMI) estimates and limits the applicability of findings to global contexts.

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DNA transfer events have been well researched in the context of commonly found items at crime scenes. However, whilst animals are a common feature of most households, transfer events involving companion animals have been understudied. Recent research has shown that dogs and cats are a reservoir of human DNA that can transfer to a hand or sterile object after a short contact.

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Prioritizing patterns in evidence: Applying the analysis of competing hypotheses framework to criminal investigations and cold cases.

Sci Justice

September 2025

Researchers in Behaviour Sequence Analysis (ReBSA), Australia; Forensic Linguistics Analysis Group (FLAG), Australia; School of Law and Criminology, Murdoch University, Perth, Australia. Electronic address:

Police investigations often give rise to multiple hypothetical pathways for how the crime was conducted. Investigators may develop several hypotheses, often based on different pieces of evidence. It is often the case that investigators have too many potential hypotheses rather than too few.

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What drives road rage? A systematic review on the psychological correlates of aggressive driving behavior.

J Safety Res

September 2025

MAIC/UniSC Road Safety Research Collaboration, University of the Sunshine Coast, 90 Sippy Downs Drive, Sippy Downs, Queensland 4556, Australia.

Introduction: Despite decades of research and intervention, aggressive driving behavior (ADB) remains a prevalent risk on our roads. This study aimed to systematically review how drivers' personality traits, perceptual tendencies, self-regulatory capacity, and psychological functioning, have been linked to the engagement of ADBs.

Method: Under guidance of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, a literature search was performed in four databases, followed by a manual search in Google Scholar.

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Introduction: Drowsiness is a significant cause of crashes in the various transport industries, including automotive, aviation, and rail. Our previous study investigated the differential induction of drowsiness in drivers caused by specific whole-body vibration (WBV) frequency ranges, with an amplitude of 0.2 m/s r.

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Crafting safety in the storm: An occupational health and safety professionals' job crafting scale.

J Safety Res

September 2025

Department of Human Resource Management & Employment Relations, King's Business School, King's College London, London WC2B 4BG, United Kingdom; Department of Medical Research, China Medical University Hospital, China Medical University, Taiwan 404 Taichung Taiwan.

Introduction: This study aims to develop and validate a job crafting scale designed specifically for occupational health and safety (OHS) professionals working in a crisis environment. Job crafting, defined as the proactive adjustment of job roles to better align with individual preferences and strengths, is recognized as a valuable strategy for enhancing job satisfaction, engagement, and performance in various occupational settings. However, existing job crafting scales primarily focus on general work contexts and cannot fully capture the unique dimensions of job crafting relevant to OHS professionals in a crisis response context.

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A systematic review on the factors associated with the accuracy of self-estimated alcohol intoxication: Implications for drink driving.

J Safety Res

September 2025

MAIC/UniSC Road Safety Research Collaboration, University of the Sunshine Coast, 90 Sippy Downs Dr, Sippy Downs, Queensland 4556, Australia.

Introduction: Drink driving is a dangerous behavior associated with significant road trauma. The ability to estimate one's alcohol plays an important role in the decision to drink and drive. This systematic review aimed to synthesize the evidence regarding what factors are associated with the accuracy of self-estimated blood and breath alcohol concentrations (BAC/BrAC) and discuss relevant implications for drink driving.

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Introduction: Some medical conditions may be associated with increased risks of collision and poor performance while driving. Traffic crashes could result in fatalities and injuries. The Australian national medical guidelines do not provide specific instructions for all medical conditions.

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Self-reported risk taking predicts handrail use on a stepladder in older adults.

J Safety Res

September 2025

Department of Bioengineering, University of Pittsburgh, 301 Schenley Place, 4420 Bayard Street, Pittsburgh, PA 15213, USA.

Objective: Identify individual factors that predict handrail use and quantify the impact of handrail use on balance while using a stepladder.

Background: Ladders are among the riskiest consumer products especially for older adults. Individual factors such as physiological capacity or risk-taking propensity have been found to influence safety behaviors and fall risk.

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Introduction: Despite ongoing efforts to deter drink-driving, it remains a significant contributor to fatal vehicle crashes. This study aimed to investigate the influence of at-risk psychological traits, alcohol-related experiences, and problematic mentalities towards the deterrence of drink-driving.

Method: An online survey was shared with a sample of Australians who use alcohol (N = 597), and the responses were analyzed using cluster, comparative, and correlational-based analyses.

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Safety and Effectiveness of Statins for Primary Prevention in Adults With Type 1 Diabetes: An Emulation.

J Am Coll Cardiol

September 2025

Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region of China; Advanced Data Analytics for Medical Science Limited, Hong Kong Special Administrative Region of China

Background: There is no consensus for using statins for primary prevention of cardiovascular disease (CVD) and all-cause mortality in adults with type 1 diabetes mellitus (T1DM), because no randomized controlled trial has exclusively investigated statins in this population.

Objectives: In this study, the authors sought to evaluate the long-term risks and benefits of statins for primary prevention in adults with T1DM.

Methods: We performed a sequential target trial emulation comparing statin initiation vs noninitiation using UK primary care data from the IQVIA Medical Research Data database.

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Effect of an integrated care model on ST-segment elevation myocardial infarction management in China: a prospective, multicentre, non-randomised controlled study.

Heart

September 2025

Department of Cardiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China.

Background: Early reperfusion therapy is critical in patients with ST-segment elevation myocardial infarction (STEMI). However, limitations in resources and patient-level and system-level barriers delay the administration of reperfusion therapy. This study evaluated the impact of an integrated care strategy for STEMI management in China.

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Objective: To report the prevalence of mental health symptoms and influencing factors in retired professional high contact team sport (HCTS) athletes.

Design: Mixed-methods systematic review.

Data Sources: PsycINFO, Embase, Medline, SPORTDiscus and Scopus were searched in July 2023 and March 2025.

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Objectives: To address the lack of accurate and accessible mental health medicines-information resources for children, young people and their parents/guardians using design thinking to co-design free-to-use, video resources tailored to this audience.

Design: A multiphase qualitative case study using the Double Diamond model of Design Thinking: Discover, Define, Develop and Deliver. This included iterative prototyping, thematic analysis and public and patient involvement throughout.

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Nutritionally Relevant Technological Advancements in Professional Cycling.

Int J Sport Nutr Exerc Metab

September 2025

Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, VIC, Australia.

Technological innovations can provide cyclists and their support team additional data. These data have potential to improve understanding of performance determinants and could be used to identify and tailor nutritional strategies to improve cycling performance. This potential, however, is dependent on the quality, interpretation, and practical use of the data generated.

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Cutaneous myiasis in a Serbian traveller returning from Kenya.

Travel Med Infect Dis

September 2025

Department of Veterinary Biosciences, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria 3010, Australia.

Background: Cutaneous myiasis is an ectoparasitic disease caused by fly larvae. In non-endemic regions it is rare, often unfamiliar to clinicians and readily misdiagnosed.

Case Presentation: A 24-year-old Serbian traveller developed painful furuncular lesions on the thigh after returning from Kenya.

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Objective: To examine trends in treatment strategies and perioperative outcomes for intact and ruptured complex abdominal aortic aneurysms (cAAA) across seven countries.

Design: Multinational, registry-based observational study within the VASCUNET framework.

Methods: This study used aggregated data from vascular registries in Australia, Denmark, Finland, New Zealand, Portugal, Sweden, and Switzerland.

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Pediatric bronchiectasis action management plan to improve clinical outcomes: An RCT.

Chest

September 2025

Child and Maternal Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; School of Nursing and Midwifery, Charles Darwin University, Darwin, Northern Territory, Australia.

Background: Managing bronchiectasis exacerbations is a priority for patients/parents/caregivers of children with bronchiectasis, yet evidence-based strategies among the pediatric population remain limited.

Research Question: Does the use of a personalized, written bronchiectasis action management plan (BAMP), compared to standard care, reduce non-scheduled doctor visits among children/adolescents with chronic suppurative lung disease (CSLD)/bronchiectasis?

Study Design And Methods: Our multicenter, double-blind, superiority, randomized controlled trial enrolled children from three Australian respiratory departments between June 2018 and December 2020. Children/adolescents aged <19 years with CSLD/bronchiectasis were randomized to receive a personalized BAMP (intervention) or standard care (controls).

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Modelling challenges to unlock the power of phototrophic systems for wastewater valorization.

Biotechnol Adv

September 2025

Department of Environmental and Resource Engineering, Technical University of Denmark, Bygningstorvet, Bygning 115, 2800 Kgs, Lyngby, Denmark.

Phototrophic microorganisms are gaining prominence for their dual role in wastewater treatment and resource recovery, converting wastewater into valuable bioproducts. However, their effective deployment needs robust modelling frameworks capable of predicting performance across complex, real-world scenarios. Despite significant advances, key challenges hinder the development and application of such models.

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Blood transcriptomic analysis reveals a distinct molecular subtype of treatment resistant depression compared to non-treatment resistant depression.

Brain Behav Immun

September 2025

Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology (BIST), Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Biomedical Research Networking Center for Rare Diseases (CIBERER), Barcelona 08003, Spain.

Treatment-resistant depression (TRD) is a severe condition characterized by chronic and recurrent depressive symptoms, leading to significant morbidity and a considerable socio-economic impact. Genetic and biological studies suggest that TRD is associated with distinct biological characteristics. In this study, we analysed whole-transcriptome differences in 293 patients with major depressive disorder (MDD) to compare TRD (N = 150) vs non-TRD (N = 143) cases.

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Phosphorylation of histone lysine demethylases is an important mechanism by which the cell modulates chromatin dynamics to regulate its response to stress. There is evidence that the Saccharomyces cerevisiae H3K36me2/3 demethylase, Rph1p, is an integrator of many signalling events. However, the regulatory function of most Rph1p phosphosites in stress response pathways remains unknown.

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