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Context: Cardiovascular protective properties of berries have been reported in numerous studies. Berries and their bioactive compounds may also be effective for improving body composition and anthropometric indices.
Objective: This systematic review and meta-analysis were aimed to investigate the effect of berries on anthropometric markers.
Data Sources: A systematic search for studies published before June 2024 was conducted in 4 electronic databases-PubMed, Scopus, Web of Science and Google Scholar-to find randomized controlled trials that used berries or their extract as the intervention.
Data Extraction: Data from 42 intervention arms from 38 studies were included in the analysis.
Data Analysis: The meta-analysis revealed a statistically significant decrease in body mass index (weighted mean difference [WMD] = -0.13 [95% CI, -0.22 to -0.04]; P = .004) and in body fat percentage (WMD = -0.50 [95% CI, -0.77 to -0.23]; P = .000) and body fat mass (WMD = -0.67 [95% CI, -1.19 to -0.16]; P = .010). No significant changes were observed in weight, waist circumference, hip circumference, waist-to-hip ratio, or fat-free mass.
Conclusion: The results indicate the potential of berries to improve body mass index and body fat percentage; however, due to limited data, more well-designed studies are recommended.
Systematic Review Registration: PROSPERO registration No. CRD42024556011.
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http://dx.doi.org/10.1093/nutrit/nuaf153 | DOI Listing |
Proc Natl Acad Sci U S A
September 2025
Department of Biochemical Pathophysiology, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
Adrenal lipomas are benign tumors containing ectopic adipose tissue in the adrenal gland, an organ that normally lacks both adipocytes and their progenitors. The origin of this ectopic fat remains enigmatic, and the absence of a genetic animal model has hindered its investigation. Phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P], a key signaling lipid that regulates cellular growth and differentiation, is tightly regulated by the lipid phosphatases PTEN (phosphatase and tensin homolog) and SHIP2 (SH2-containing inositol phosphatase 2).
View Article and Find Full Text PDFAbdom Radiol (NY)
September 2025
Department of Gastroenterology department, Bishan Hospital of Chongqing Medical University, Chongqing, China.
Objective: This study aimed to create and validate a nomogram to predict early recurrence (ER) in Colorectal cancer (CRC) patients by combining CT-derived abdominal fat parameters with clinical and pathological characteristics.
Methods: We conducted a retrospective analysis of 206 CRC patients, dividing them into training (n = 146) and validation (n = 60) cohorts. We quantified abdominal fat parameters, including subcutaneous adipose tissue index (SATI) and visceral adipose tissue index (VATI), using semi-automatic software on CT images at the level of the third lumbar vertebra (L3).
Abdom Radiol (NY)
September 2025
Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.
Objectives: The escalating global incidence of obesity, cardiometabolic disease and sarcopenia necessitates reliable body composition measurement tools. MRI-based assessment is the gold standard, with utility in both clinical and drug trial settings. This study aims to validate a new automated volumetric MRI method by comparing with manual ground truth, prior volumetric measurements, and against a new method for semi-automated single-slice area measurements.
View Article and Find Full Text PDFFASEB J
September 2025
Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Severe burns are a major global health concern, and are associated with long-term physical and psychological impairments, multi-organ dysfunction, and substantial morbidity and mortality. While burn injuries in adults trigger systemic immuno-metabolic alterations-characterized by white adipose tissue browning, elevated resting energy expenditure, widespread catabolism, and inflammation-these adaptive responses are considerably impaired in older adults, with molecular mechanisms behind these differences remaining largely unclear. As a key regulator of systemic metabolism, investigating the pathological role of adipose tissue (AT) postburn may reveal novel targets that could potentially improve patient outcomes.
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