Advancing future research on sepsis outcomes in adolescents with SUD: integrating AI, accounting for temporal trends, and enhancing exposure classification.

Ann Intensive Care

Pediatric Critical Care Medicine, Department of Pediatrics, Penn State Hershey Children's Hospital, 500 University Drive, P.O. Box 850, Hershey, PA, 17033-0850, USA.

Published: September 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413348PMC
http://dx.doi.org/10.1186/s13613-025-01556-7DOI Listing

Publication Analysis

Top Keywords

advancing future
4
future sepsis
4
sepsis outcomes
4
outcomes adolescents
4
adolescents sud
4
sud integrating
4
integrating accounting
4
accounting temporal
4
temporal trends
4
trends enhancing
4

Similar Publications

Integrating opinion dynamics and differential game modeling for sustainable groundwater management.

Water Res

September 2025

College of Hydrology and Water Resources, Hohai University, Nanjing 210098, China. Electronic address:

Groundwater overextraction presents persistent challenges due to strategic interdependence among decentralized users. While game-theoretic models have advanced the analysis of individual incentives and collective outcomes, most frameworks assume fully rational agents and neglect the role of cognitive and social factors. This study proposes a coupled model that integrates opinion dynamics with a differential game of groundwater extraction, capturing the interaction between institutional authority and evolving stakeholder preferences.

View Article and Find Full Text PDF

Wearable bioelectronics for skin cancer management.

Biomaterials

August 2025

Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, 90095, USA. Electronic address:

Wearable bioelectronics have transformed modern biomedical applications by enabling seamless integration with biological tissues, providing continuous, comprehensive, and personalized healthcare. Skin cancer, particularly melanoma, poses a significant clinical challenge due to its high metastatic potential and associated mortality. Traditional diagnostic approaches face limitations in accuracy, accessibility, and reproducibility, while existing treatments are often constrained by systemic toxicity and therapeutic resistance.

View Article and Find Full Text PDF

Bioactive Coatings for Cardiovascular Stents: Modulating Immune Response for Enhanced Performance.

ACS Biomater Sci Eng

September 2025

University Center for Research & Development (UCRD), Chandigarh University, NH-05 Chandigarh-Ludhiana Highway, Mohali 140413, Punjab, India.

Cardiovascular disorders remain a leading cause of death worldwide, and the use of contemporary stents is paving the way for a profound shift in the field of cardiology. In the surgical process postimplantation, the graft or stent and host-immune interaction play a significant role in the healing process, thus it is a major challenge in healthcare. To address these challenges, recent advancements have introduced bioactive coatings with specialized modifications in stents to enhance their interaction with surrounding environment.

View Article and Find Full Text PDF

The ability to synthesize lichen symbioses in vitro from pure cultures of transformable symbionts would be a game changer for experiments to identify the metabolic interplay that underpins the success of lichens. However, despite multiple reports of successful lichen resynthesis, no lichen lab model system exists today. We reviewed 150 years of in vitro lichen studies and found that the term resynthesis is applied to many types of fungal-photobiont cocultures that do not resemble lichens.

View Article and Find Full Text PDF

Background: In-hospital cardiac arrest (IHCA) remains a public health conundrum with high morbidity and mortality rates. While early identification of high-risk patients could enable preventive interventions and improve survival, evidence on the effectiveness of current prediction methods remains inconclusive. Limited research exists on patients' prearrest pathophysiological status and predictive and prognostic factors of IHCA, highlighting the need for a comprehensive synthesis of predictive methodologies.

View Article and Find Full Text PDF