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Pipkin Type III is extremely rare and is associated with worse prognosis and several complications. There is still no consensus on the management of injuries and whether these fractures should be treated surgically with ORIF or arthroplasty. Pipkin type III involves a combination of ipsilateral femoral head and neck fractures. Physioanatomical complexity of this fracture is often challenging, with a poorer prognosis than any other subgroups. The most common complications after management of Pipkin Type III are avascular necrosis of the femoral head and post-traumatic osteoarthritis. The treatment modality with open reduction and internal fixation (ORIF) or total hip arthroplasty (THA) varies according to the severity of the fracture, patient age, time to surgery, and intraoperative findings. Reoperation and surgical intervention pose significant economic burden, functional impairment, and quality of life. This comprehensive review on Pipkin type III demonstrates a throughout exploration of the existing research publications and case studies, focusing on current understanding treatment management strategies, outcome associated and decision-making frameworks with algorithms for decision schemes. By incorporating additional references of our institutional experiences, it aims to expand the current body of knowledge on Pipkin III fractures, offering fresh perspectives and crucial insights for surgeons in decision-making processes.
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http://dx.doi.org/10.3389/fsurg.2025.1554603 | DOI Listing |
Front Surg
August 2025
West China School of Medicine, West China Hospital, Sichuan University, Chengdu, China.
Pipkin Type III is extremely rare and is associated with worse prognosis and several complications. There is still no consensus on the management of injuries and whether these fractures should be treated surgically with ORIF or arthroplasty. Pipkin type III involves a combination of ipsilateral femoral head and neck fractures.
View Article and Find Full Text PDFArch Orthop Trauma Surg
August 2025
Center for Musculoskeletal Surgery, Charitè-University Medicine Berlin, Berlin, Germany.
Background: Traumatic hip dislocations are rare but serious injuries, potentially affecting patients' quality of life and mobility. Given the limited understanding of prognostic factors, this study aimed to identify predictors of long-term clinical outcomes.
Materials And Methods: Injury characteristics and computed tomography (CT) of patients following traumatic hip dislocation from two level I trauma centers from 2009 to 2015 were analyzed.
J Orthop Surg Res
August 2025
Health Science Center, Ningbo University, Ningbo, 315211, Zhejiang, China.
Purpose: To evaluate the surgical technique and clinical outcomes of the Universal Self-locking Anatomic Plate for Acetabulum (USAPA).
Methods: A retrospective analysis of 155 patients with complete follow-up data from December 2014 to December 2020 was conducted. The study included 119 males and 36 females, aged 18–82 (mean: 40.
J Phys Chem B
August 2025
School of Applied and Interdisciplinary Sciences, Indian Association for the Cultivation of Science, 2A & 2B Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
The present article describes the creation of uniformly distributed (polyalkylthiophene) (P3AT) networks with various alkyl side chains. Modulations of optical, structural, morphological, and rheological characteristics caused by the alteration of the length of the alkyl side chain in P3AT aggregates have been investigated thoroughly by temperature-dependent UV-visible studies, powder X-ray diffraction, and atomic force microscopy (AFM) studies. At a low polymer concentration, all P3ATs form networks and reveal their rheological properties.
View Article and Find Full Text PDFImmunity
July 2025
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:
Tumor-infiltrating lymphocytes (TILs) with a tissue-resident memory CD8 T cell (Trm) phenotype are associated with improved patient outcomes in solid malignancies. To define programs governing the formation of Trm-like TIL, we performed paired single-cell RNA sequencing and single-cell ATAC sequencing of T cell receptor (TCR)-matched CD8 T cells in models of infection and cancer. Enhancer-driven regulons assembled from multiomic profiling data revealed epigenetic and transcriptional programs regulating the formation of Trm-like TIL in relation to canonical exhausted and memory T cell states.
View Article and Find Full Text PDF