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Background: Suboptimal insulin injection is widely used to treat Chinese patients with diabetes, with most patients being treated in primary care institutions. However, research on community nurses' knowledge, attitude, and practice concerning insulin injection in less developed areas of China is extremely scarce.
Objective: To investigate the knowledge, attitude, and practice of community nurses concerning insulin injection in a mountainous area of southwest, Zhejiang, China.
Methods: We employed a cross-sectional study in 30 community healthcare service centers and 1911 randomly selected community nurses between 20th June to 20th July 2023. The Chinese insulin injection knowledge, attitude, and practice questionnaire was used to collect data. Descriptive, correlational, and multivariate linear regression analyses were performed by Stata version 15.0.
Results: In total, 47.7% of nurses had poor insulin injection knowledge, while only 3.7% and 2.5% had poor levels of attitude and practice concerning insulin injection. Sex, location of the institution, working period, marital status, institutional manager, knowledge of the latest guidelines, and undertaking insulin injection training over the last year (all p<0.05) were all identified as independent predictors of insulin injection knowledge. Sex, working period, experience of delivering insulin education to patients, knowledge of the latest guidelines, and undertaking insulin injection training over the previous year (all p<0.05) were identified as independent predictors of insulin injection attitude. Location of the institution, sex, knowledge of the latest guidelines, and undertaking insulin injection training over the last year (all p<0.05) were all independent predictors of insulin injection practice.
Conclusion: Community nurses in this study (Southwest Zhejiang) had relatively good attitudes and practices towards insulin injection, although their specific knowledge was poor. Sex, location of the institution, working period, marital status, knowledge of the guidelines, experience in delivering education, and training experience exhibited significant relationships with the knowledge, attitude, and practice of insulin injection. Therefore, effective tailored, standardized guideline-based training should be recommended to improve the knowledge, attitude, and practice of community nurses regarding insulin injection, especially for married and younger male nurses.
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http://dx.doi.org/10.3389/fendo.2025.1501992 | DOI Listing |
Pharmacol Biochem Behav
September 2025
Departamento de Psicobiología y Metodología de las Ciencias del Comportamiento, Universidad de Málaga (UMA), Málaga, 29010, Spain; Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), Málaga, Spain. Electronic address:
Adolescence is a period of heightened neuroplasticity and vulnerability to environmental insults, including drug exposure. In this study, we investigated the short- and long-term behavioral effects, as well as the long-term hippocampal effects, of chronic cocaine administration during adolescence, along with the potential neuroprotective role of insulin-like growth factor 2 (IGF2) in male C57BL/6J mice. Over 21 days, mice received daily intraperitoneal injections of saline, cocaine, IGF2, or a combination of cocaine and IGF2.
View Article and Find Full Text PDFG Ital Nefrol
August 2025
Infermiere Professionale SSD Nefrologia e Dialisi P.O. Soverato, ASP CZ.
Management of diabetes mellitus in hemodialysis is highly complex due to increased glycemic variability and hypoglycemic risk. The use of technologies applied to diabetes has been shown to improve glycemic control, however data in dialysis patients are limited. To describe the efficacy and safety of the minimed 780G AHCL system in a stable hemodialysis patient and during hospitalization in the Intensive Care Unit (ICU).
View Article and Find Full Text PDFAdv Pharm Bull
July 2025
Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal- 576104, India.
Purpose: The present study aimed to fabricate microneedles (MNs) for transdermal delivery of insulin. Chitosan-conjugated carboxy phenyl boronic acid polymer was synthesized and characterized to load insulin in the form of nanoparticles.
Methods: Optimized insulin nanoparticles (ILN-NPs) were loaded into MN arrays by micromolding, and the resulting MN patches were characterized by scanning electron microscopy (SEM) and mechanical failure tests.
Bone Jt Open
September 2025
Leeds General Infirmary, Leeds, UK.
Aims: The primary outcome was to determine the proportion of patients with adhesive capsulitis who required reintervention following a treatment of hydrodistension. The secondary outcome was to identify predictors of reintervention.
Methods: A total of 712 hydrodistension procedures from six NHS trusts were included for statistical analysis.
Front Endocrinol (Lausanne)
September 2025
Department of Obstetrics and Gynecology, Center for Reproductive Medicine, The Fourth Affiliated Hospital of School of Medicine and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, China.
Background: Obesity is associated with hormonal imbalance, increased oxidative stress, and inflammation in the testis. These conditions adversely affect sperm quality, leading to impaired male fertility. Therefore, therapeutic interventions to counteract the adverse effects of obesity are crucial.
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